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    • 1. 发明申请
    • NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS
    • 萘普生异佛胺异构体杀虫剂控制剂
    • WO2009002809A3
    • 2009-03-19
    • PCT/US2008067576
    • 2008-06-20
    • DU PONTLAHM GEORGE PHILIPLONG JEFFREY KEITHXU MING
    • LAHM GEORGE PHILIPLONG JEFFREY KEITHXU MING
    • C07D261/04A01N43/80
    • A01N43/80C07D261/04
    • Disclosed are compounds of Formula (I), wherein R1 is halogen, C1-C2 haloalkyl or C1-C2 haloalkoxy; R2 is H, halogen or cyano; R3 is H, halogen or CF3; R4 is H, C2-C7 alkylcarbonyl or C2-C7 alkoxycarbonyl; and R5 is C1-C6 alkyl or C1-C6 haloalkyl, each substituted with one substituent independently selected from hydroxy, C1-C6 alkoxy, C1-C6 alkylthio, C1-C6 alkylsulfinyl, C1-C6 alkylsulfonyl, C2-C7 alkylaminocarbonyl, C3-C9 dialkylaminocarbonyl, C2-C7 haloalkylaminocarbonyl and C3-C9 halodialkylaminocarbonyl. Also disclosed are compositions containing the compounds of Formula (I) and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.
    • 公开了式(I)的化合物,其中R 1是卤素,C 1 -C 2卤代烷基或C 1 -C 2卤代烷氧基; R2是H,卤素或氰基; R3是H,卤素或CF3; R4是H,C2-C7烷基羰基或C2-C7烷氧基羰基; 并且R 5是被一个独立地选自羟基,C 1 -C 6烷氧基,C 1 -C 6烷硫基,C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基磺酰基,C 2 -C 7烷基氨基羰基,C 3 -C 6烷基氨基羰基, C 9二烷基氨基羰基,C 2 -C 7卤代烷基氨基羰基和C 3 -C 9卤代二烷基氨基羰基。 还公开了含有式(I)化合物和控制无脊椎动物害虫的方法的组合物,其包括使无脊椎害虫或其环境与生物有效量的本发明化合物或组合物接触。
    • 3. 发明申请
    • 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS
    • 用于控制反相胶束的5-ARYL ISOXAZOLINES
    • WO2007075459A2
    • 2007-07-05
    • PCT/US2006/047999
    • 2006-12-15
    • E. I. DU PONT DE NEMOURS AND COMPANYLAHM, George, PhilipPATEL, Kanu, MaganbhaiPAHUTSKI, Thomas, Francis, Jr.,SMITH, Benjamin, Kenneth
    • LAHM, George, PhilipPATEL, Kanu, MaganbhaiPAHUTSKI, Thomas, Francis, Jr.,SMITH, Benjamin, Kenneth
    • C07D413/14A01N43/80C07D261/04C07D413/04C07D413/10C07D413/12C07D417/10C07D417/14
    • Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N -oxides, and salts thereof, wherein A 1 , A 2 and A 3 are independently selected from the group consisting of CR 3 and N; B 1 B 2 and B 3 are independently selected from the group consisting of CR 2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -CN, -NO 2 , -N(R 4 )R 5 , -C(W)N(R4)R 5 , -C(O)OR 5 and R 8 ; or -S(O) 2 N(R 2I )R 22 , -S(O) p R 25 or -S(O)(=NR 28 )R 29 ; and R l , R 2 , R 3 , R 4 , R 5 , R 8 , R 21 , R 22 , R 25 , R 28 , R 29 ; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition' of the invention.
    • 公开了式1的化合物,包括所有几何和立体异构体,N-氧化物及其盐,其中A 1,A 2和A 3 >独立地选自CR 3和N; B 1,B 2,B 3和B 3独立地选自CR 2和N; Q是苯环或5或6元饱和或不饱和杂环,每个环任选地被一个或多个独立地选自卤素,C 1 -C 6 - C 1 -C 6烷基,C 1 -C 6卤代烷基,C 3 -C 6环烷基,C 1 -C 6烷基, C 3 -C 6卤代环烷基,C 1 -C 6烷氧基,C 1 -C 6烷基,C 1 -C 6烷基, C 1 -C 6卤代烷氧基,C 1 -C 6烷硫基,C 1 -C 6卤代烷硫基 C 1 -C 6烷基亚磺酰基,C 1 -C 6卤代烷基亚磺酰基,C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基亚磺酰基, C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基,-CN,-NO 2 - , - N(R 4)R 5,-C(W)N(R 4)R 5,-C(O)OR 5< 8>; 或-S(O)2 N(R 2 2)R 22,-S(O)p R 或-S(O)(= NR 28)R 29; 和R 1,R 2,R 3,R 4,R 5, R 8,R 21,R 22,R 25,R 28, R 29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物,其包括使无脊椎害虫或其环境与生物有效量的本发明的化合物或组合物接触。
    • 4. 发明申请
    • ANTHRANILAMIDE INSECTICIDES
    • 蒽威杀虫剂
    • WO2006055922A2
    • 2006-05-26
    • PCT/US2005042196
    • 2005-11-18
    • DU PONTLAHM GEORGE PHILIPSELBY THOMAS PAULSTEVENSON THOMAS MARTINTAGGI ANDREW EDMUNDBEREZNAK JAMES FRANCIS
    • LAHM GEORGE PHILIPSELBY THOMAS PAULSTEVENSON THOMAS MARTINTAGGI ANDREW EDMUNDBEREZNAK JAMES FRANCIS
    • C07D231/16A01N43/56C07D401/04C07D405/12C07D405/14A01N51/00A01N47/40A01N2300/00
    • Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein J is a phenyl optionally substituted with one to four substituents independently selected from R 5 ; or J is a heterocyclic ring selected from the group consisting of J-1 to J-8; R 4 is C 4 -C 12 alkylcycloalkyl, C 5 -C 12 alkenylcycloalkyl, C 5 -C 12 alkynylcycloalkyl, C 4 -C 12 cycloalkylalkyl, C 5 -C 12 cycloalkylalkenyl, C 5 -C 12 cycloalkylalkynyl, C 4 -C 12 cycloalkenylalkyl or C 4 -C 12 alkylcycloalkenyl; each optionally substituted with one to six substituents selected from CH 3 and halogen; or R 4 is C 3 -C 5 oxiranylalkyl, C 3 -C 5 thiiranylalkyl, C 4 -C 6 oxetanylalkyl, C 4 -C 6 thietanylalkyl, 3-oxetanyl or 3-thietanyl, each optionally substituted with one to five substituents independently selected from C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, halogen, CN, C 2 -C 4 alkoxycarbonyl and C 2 -C 4 haloalkoxycarbonyl; or R 4 is C 3 -C 5 aziridinylalkyl, C 4 -C 6 azetidinylalkyl or 3-azetidinyl, each with R 10 attached to the nitrogen atom, and optionally substituted on carbon atoms with one to five substituents independently selected from C l -C 3 alkyl, C 1 -C 3 haloalkyl, halogen, CN, C 2 -C 4 alkoxycarbonyl and C 2 -C 4 haloalkoxycarbonyl; and R la
    • 公开了式1的化合物,包括所有几何和立体异构体,N-氧化物及其盐,其中J是任选被独立选自R 5的一至四个取代基取代的苯基; 或J是选自J-1至J-8的杂环; R 4是C 4 -C 12烷基环烷基,C 5 -C 12烷基,C 5 -C 12芳基, 烯基环烷基,C 5 -C 12炔基环烷基,C 4 -C 12环烷基烷基,C 5 -C 10环烷基烷基, C 12环烷基链烯基,C 5 -C 12环烷基炔基,C 4 -C 12环烷基炔基, 12环烯基烷基或C 4 -C 12烷基环烯基; 各自任选被1至6个选自CH 3和卤素的取代基取代; 或R 4是C 3 -C 5环氧乙烷基烷基,C 3 -C 5 S >噻吩基烷基,C 4 -C 6氧杂环丁基烷基,C 4 -C 6硫杂环丁基烷基,3-氧杂环丁烷基或3-氧杂环丁烷基 - 各自任选被1至5个独立选自以下的取代基取代:-C 1 -C 3烷基,C 1 -C 3烷基, 卤代烷基,CN,C 2 -C 4烷氧基羰基和C 2 -C 4烷基, 卤代烷; 或R 4是C 3 -C 5的氮丙啶基烷基,C 4 -C 6的 1
    • 6. 发明申请
    • ANTHRANILAMIDE INSECTICIDES
    • WO2004033468A1
    • 2004-04-22
    • PCT/US2003/031677
    • 2003-10-01
    • E.I. DU PONT DE NEMOURS AND COMPANYLAHM, George, PhilipSELBY, Thomas, PaulSTEVENSON, Thomas, Martin
    • LAHM, George, PhilipSELBY, Thomas, PaulSTEVENSON, Thomas, Martin
    • C07F7/08
    • A01N55/00C07F7/0812
    • This invention provides compounds of Formula I, N-oxides and suitable salts thereof (INSERT FORMULA I HERE) wherein A is O or S(O)?m#191;J is a phenyl or heterocyclic ring as defined herein; andR 1 through R 12 , n, m and r are as defined in the disclosure.Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula I, an N -oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula I, an N -oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.
    • 本发明提供式I化合物,N-氧化物及其合适的盐(其中A为O或S(O)m = 191; J为如本文所定义的苯基或杂环; 并且R> 1 12 <,n,m和r如本公开中所定义。还公开了用于控制无脊椎害虫的方法,包括使无脊椎害虫或其环境与生物有效量的式I化合物 ,其N-氧化物或该化合物的合适盐(例如,作为本文所述的组合物)。 本发明还涉及用于控制无脊椎害虫的组合物,其包含生物有效量的式I化合物,其N-氧化物或该化合物的合适盐和至少一种选自表面活性剂 ,固体稀释剂和液体稀释剂。
    • 7. 发明申请
    • ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS
    • 用于控制反相胶束的OROO-杂环取代的芳基
    • WO2003016304A1
    • 2003-02-27
    • PCT/US2002/026968
    • 2002-08-12
    • E. I. DU PONT DE NEMOURS AND COMPANYCLARK, David, AlanFINKELSTEIN, Bruce, LawrenceLAHM, George, PhilipSELBY, Tom, PaulSTEVENSON, Thomas, Martin
    • CLARK, David, AlanFINKELSTEIN, Bruce, LawrenceLAHM, George, PhilipSELBY, Tom, PaulSTEVENSON, Thomas, Martin
    • C07D401/14
    • C07D401/12A01N43/56A01N43/76C07D401/14C07D403/12C07D413/14
    • This invention pertains to compounds of Formula I, their N-oxides and suitable salts (Formula I) wherein A is O or S; G is a 5- or 6-membered heteroaromatic ring or a 5- or 6-membered nonaromatic heterocyclic ring optionally including one or two ring members selected from the group consisting of C(=O), SO or S(O) 2 , each ring optionally substituted with from one to four R 2 ; each J is independently a phenyl ring, a 5- or 6-membered heteroaromatic ring or an aromatic 8-, 9- or 10-membered fused carbobicyclic or heterobicyclic ring system, wherein each ring or ring system is optionally substituted with from one to four R 3 ; and R 1 , R 2 , R 3 , R 4 and n are as defined in the disclosure.Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula I, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula I, an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid diluents.
    • 本发明涉及式I化合物,其N-氧化物和适宜的盐(式I),其中A为O或S; G是5-或6-元杂芳环或5或6元非芳族杂环,任选地包括选自C(= O),SO或S(O)2)的一个或两个环成员, 任选被一至四个R 2取代的环; 每个J独立地是苯环,5或6元杂芳族环或芳族8,9-或10元稠合的碳双环或杂双环系统,其中每个环或环系统任选被一至四个 [R <3>; R 1,R 2,R 3,R 4和n如本公开所定义。还公开了控制无脊椎害虫的方法,包括使无脊椎害虫或其环境与生物有效的 量的式I化合物,其N-氧化物或该化合物的合适盐(例如,作为本文所述的组合物)。 本发明还涉及用于控制无脊椎害虫的组合物,其包含生物有效量的式I化合物,其N-氧化物或该化合物的合适盐,以及至少一种选自表面活性剂, 固体稀释剂和液体稀释剂。
    • 10. 发明申请
    • ANIMAL PEST CONTROL METHOD
    • 动物虫控制方法
    • WO2009003075A1
    • 2008-12-31
    • PCT/US2008/068268
    • 2008-06-26
    • E.I. DU PONT DE NEMOURS AND COMPANYLAHM, George, PhilipLONG, Jeffrey, KeithXU, Ming
    • LAHM, George, PhilipLONG, Jeffrey, KeithXU, Ming
    • A61K31/42A61P33/00
    • A61K31/4439A01N43/80A61K9/0019A61K9/0053A61K31/42
    • Disclosed is a method for protecting an animal from a parasitic invertebrate pest comprising treating an animal orally or by injection with a pesticidally effective amount of a compound of Formula: (1), wherein R 1 is halogen, C 1 -C 3 haloalkyl or C 1 -C 3 haloalkoxy; R 2 is H, halogen, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl or cyano; R 3 is H, halogen, C 1 -C 3 haloalkyl or C 1 -C 3 haloalkoxy; R 4 is halogen, C 1 -C 3 alkyl, C1-C3 haloalkyl or C 1 -C 3 haloalkoxy; R 5 is H, CH 3 , C 2 -C 4 alkylcarbonyl, C 2 -C 4 haloalkylcarbonyl, C 2 -C 5 alkoxycarbonyl or CH 2 O(C 1 -C 3 alkyl); R 6 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl or C 3 -C 6 halocycloalkyl, each group substituted with one R 7 ; or R 6 is (CH 2 ) m Q; and Q, R 7 , R 8a and R 8b are as defined in the disclosure.
    • 公开了一种保护动物免受寄生的无脊椎害虫的方法,包括用杀虫有效量的式(1)化合物口服或注射处理动物:其中R1是卤素,C1-C3卤代烷基或C1-C3卤代烷氧基 ; R2是H,卤素,C1-C3烷基,C1-C3卤代烷基或氰基; R3是H,卤素,C1-C3卤代烷基或C1-C3卤代烷氧基; R4是卤素,C1-C3烷基,C1-C3卤代烷基或C1-C3卤代烷氧基; R5是H,CH3,C2-C4烷基羰基,C2-C4卤代烷基羰基,C2-C5烷氧基羰基或CH2O(C1-C3烷基); R6是C1-C6烷基,C1-C6卤代烷基,C3-C6环烷基或C3-C6卤代环烷基,每个基团被一个R7取代; 或R6是(CH2)mQ; 并且Q,R7,R8a和R8b如本公开所定义。