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1. 发明申请

WO2013187554A1 In GENE FOR CONTROLLING NUMBER OF SEEDS PER POD IN SOYBEAN AND USES THEREOF 审中-公开
标题翻译：用于控制大豆种子数目的基因及其用途
公开(公告)号：WO2013187554A1
公开(公告)日：2013-12-19
申请号：PCT/KR2012/007066
申请日：2012-09-04
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , JEONG, Soon Chun , JEONG, Nam Hee , SUH, Su Jeoung , KIM, Min Hee , MOON, Jung Kyung , KIM, Hyoung Chin
发明人： JEONG, Soon Chun , JEONG, Nam Hee , SUH, Su Jeoung , KIM, Min Hee , MOON, Jung Kyung , KIM, Hyoung Chin
IPC分类号： A01H5/00 , C12N15/29 , C12N15/82
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The present invention relates to ln gene produced by single nucleotide substitution in EAR motif of leaf shape-controlling Ln (broad leaflet) gene from soybean ( Glycine max ), a recombinant vector comprising the ln gene gene, a host cell transformed with recombinant vector, a method of controlling the number of seeds per pod by using the ln gene, a method of producing a plant with controlled number of seeds per pod by using the ln gene, a transformed plant with controlled number of seeds per pod that is produced by the method, seeds thereof, and a composition for controlling the number of seeds per pod in a plant comprising the recombinant vector comprising the ln gene.
摘要翻译：本发明涉及由来自大豆（Glycine max）的叶形状控制Ln（阔叶）基因的EAR基序中的单核苷酸取代产生的ln基因，包含ln基因的重组载体，用重组载体转化的宿主细胞，通过使用ln基因控制每个荚果的种子数量的方法，通过使用ln基因产生具有受控数量的种子的荚果的植物的方法，每个荚果的受控数量的种子的转化植物，其由方法，其种子和用于控制植物中每个荚果种子数目的组合物，其包含含有该ln基因的重组载体。

2. 发明申请

WO2005084141A3 NOVEL ABIETANE DITERPENOID COMPOUND, AND COMPOSITION COMPRISING EXTRACT OF TORREYA NUCIFERA, OR ABIETANE DITERPENOID COMPOUNDS OR TERPENOID COMPOUNDS ISOLATED FROM THEM FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE 审中-公开
标题翻译：新戊酰氨基磷酸酯化合物，以及包含TORREYA NUCIFERA或ABIETANE DITERPENOID化合物的提取物的组合物或其分离自他们的用于预防和治疗心血管疾病的TERPENOID化合物
公开(公告)号：WO2005084141A3
公开(公告)日：2005-11-17
申请号：PCT/KR2005000472
申请日：2005-02-22
申请人： KOREA RES INST OF BIOSCIENCE , JEONG TAE-SOOK , LEE WOO-SONG , KIM HYOUNG-CHIN , CHOI YANG-KYU , KIM JU-RYOUNG , AN SO-JIN , IM KYOUNG-RAN , JANG KI-CHANG , MOON OG-SUNG , SON JUN-SEOCK
发明人： JEONG TAE-SOOK , LEE WOO-SONG , KIM HYOUNG-CHIN , CHOI YANG-KYU , KIM JU-RYOUNG , AN SO-JIN , IM KYOUNG-RAN , JANG KI-CHANG , MOON OG-SUNG , SON JUN-SEOCK
IPC分类号： A61K36/13 , C07C33/38 , C07C37/00 , C07C39/17 , C07C43/315 , C07C45/78 , C07C47/45 , C07C61/35
CPC分类号： C07C33/38 , A61K36/13 , C07C37/004 , C07C39/17 , C07C41/58 , C07C43/315 , C07C45/78 , C07C47/45 , C07C61/35 , C07C2603/26
摘要： The present invention relates to a composition for the prevention and the treatment of cardiovascular disease containing extracts of T. nucifera or abietane diterpenoid compound or terpenoid compound isolated from the same as an effective ingredient. T. nucifera extracts or abietane diterpenoid compound or terpenoid compound isolated from the same of the present invention not only shows excellent anti-oxidative activity to LDL but also effectively inhibits ACAT activity. Further, T. nucifera extracts of the present invention reduce blood LDL cholesterol and total cholesterol. Therefore, the composition of the present invention can be effectively used for the prevention and the treatment of cardiovascular diseases including hyperlipidemia and atherosclerosis caused by the LDL oxidation and the synthesis and accumulation of cholesteryl ester.
摘要翻译：本发明涉及一种用于预防和治疗含有不同于有效成分的不分泌的无花果或非天冬氨酸二萜化合物或萜类化合物的心血管疾病的组合物。从本发明的相同方式分离的无花果提取物或二亚烷基二萜化合物或萜类化合物不仅对LDL显示优异的抗氧化活性，而且还有效抑制ACAT活性。此外，本发明的美洲黑提取物降低血液中的低密度脂蛋白胆固醇和总胆固醇。因此，本发明的组合物可以有效地用于预防和治疗由LDL氧化和胆固醇酯的合成和积累引起的高脂血症和动脉粥样硬化的心血管疾病。

3. 发明申请

WO2012064096A2 NOVEL STRAIN OF BACILLUS SUBTILIS, AND USE THEREOF FOR PREVENTING ROOT ROT DISEASE IN PLANTS 审中-公开
标题翻译：新鲜菌丝芽孢杆菌及其用于预防植物根系疾病的用途
公开(公告)号：WO2012064096A2
公开(公告)日：2012-05-18
申请号：PCT/KR2011008496
申请日：2011-11-09
申请人： KOREA RES INST OF BIOSCIENCE , KIM YOUNG KOOK , KIM JOONG SU , KIM HYOUNG CHIN , BAE KYUNG SOOK
发明人： KIM YOUNG KOOK , KIM JOONG SU , KIM HYOUNG CHIN , BAE KYUNG SOOK
IPC分类号： C12N1/20 , A01N63/02 , C12R1/125
CPC分类号： C12R1/125 , A01N63/00
摘要： The present invention relates to a novel strain of Bacillus subtilis, and more particularly, to the B-5604 strain of Bacillus subtilis, which inhibits the growth of root rot pathogens, to a composition containing said strain or the culture medium thereof for controlling root rot pathogens, to a method for controlling ginseng root rot pathogens using said composition, and to a method for inhibiting the growth of Cylindrocarpon destructans or Fusarium solani using said strain. The microorganisms having antagonistic activity developed according to the present invention are not harmful to water and soil, and thus does not cause environmental pollution, and particularly, the microorganisms having antagonistic activity according to the present invention may not only reduce root rot pathogens in farmland in which ginseng is repeatedly cultivated or recultivated, but also alleviate root rot disease in ginseng being cultivated, thus significantly contributing to ginseng cultivation.
摘要翻译：本发明涉及一种新的枯草芽孢杆菌菌株，更具体地说，涉及一种抑制根腐病原体生长的枯草芽孢杆菌B-5604菌株，所述组合物含有所述菌株或其培养基用于控制根腐病病原体，使用所述组合物控制人参根腐病病原体的方法，以及使用所述菌株抑制茄子根腐病菌或茄病镰刀菌生长的方法。根据本发明开发的具有拮抗活性的微生物对水和土壤无害，因此不会引起环境污染，特别是根据本发明的具有拮抗活性的微生物不仅可以减少农田的根腐病原体人参多次栽培或重新种植，也可减轻人参中的根腐病，从而大大促进了人参的培育。

4. 发明申请

WO2005084141A2 NOVEL ABIETANE DITERPENOID COMPOUND, AND COMPOSITION COMPRISING EXTRACT OF TORREYA NUCIFERA, OR ABIETANE DITERPENOID COMPOUNDS OR TERPENOID COMPOUNDS ISOLATED FROM THEM FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE 审中-公开
标题翻译：新的ABIETANE二萜类化合物以及包含虎杖提取物或者脱乙基二萜类化合物或其类萜烯化合物的组合物用于预防和治疗心血管疾病
公开(公告)号：WO2005084141A2
公开(公告)日：2005-09-15
申请号：PCT/KR2005/000472
申请日：2005-02-22
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , JEONG, Tae-Sook , LEE, Woo-Song , KIM, Hyoung-Chin , CHOI, Yang-Kyu , KIM, Ju-Ryoung , AN, So-Jin , IM, Kyoung-Ran , JANG, Ki-Chang , MOON, Og-Sung , SON, Jun-Seock
发明人： JEONG, Tae-Sook , LEE, Woo-Song , KIM, Hyoung-Chin , CHOI, Yang-Kyu , KIM, Ju-Ryoung , AN, So-Jin , IM, Kyoung-Ran , JANG, Ki-Chang , MOON, Og-Sung , SON, Jun-Seock
IPC分类号： A61K36/13 , C07C33/38 , C07C37/00 , C07C39/17 , C07C43/315 , C07C45/78 , C07C47/45 , C07C61/35
CPC分类号： C07C33/38 , A61K36/13 , C07C37/004 , C07C39/17 , C07C41/58 , C07C43/315 , C07C45/78 , C07C47/45 , C07C61/35 , C07C2603/26
摘要： The present invention relates to a composition for the prevention and the treatment of cardiovascular disease containing extracts of T. nucifera or abietane diterpenoid compound or terpenoid compound isolated from the same as an effective ingredient. T. nucifera extracts or abietane diterpenoid compound or terpenoid compound isolated from the same of the present invention not only shows excellent anti-oxidative activity to LDL but also effectively inhibits ACAT activity. Further, T. nucifera extracts of the present invention reduce blood LDL cholesterol and total cholesterol. Therefore, the composition of the present invention can be effectively used for the prevention and the treatment of cardiovascular diseases including hyperlipidemia and atherosclerosis caused by the LDL oxidation and the synthesis and accumulation of cholesteryl ester.
摘要翻译：本发明涉及用于预防和治疗含有T的提取物的心血管疾病的组合物。 nucifera或松香二萜类化合物或从其中分离的萜类化合物作为有效成分。从本发明提取的植物提取物或松香二萜类化合物或萜类化合物不仅对LDL显示出优异的抗氧化活性，而且还有效地抑制ACAT活性。此外，T。本发明的胡桃提取物可降低血液中的LDL胆固醇和总胆固醇。因此，本发明的组合物可以有效地用于预防和治疗心血管疾病，包括LDL氧化引起的高脂血症和动脉粥样硬化以及胆固醇酯的合成和积累。

5. 发明申请

WO2002085350A1 PRODIGIOSIN COMPOSITION FOR THE TREATMENT OF RHEUMATIC ARTHRITIS 审中-公开
标题翻译：用于治疗感染性ARTHRITIS的原料药组合物
公开(公告)号：WO2002085350A1
公开(公告)日：2002-10-31
申请号：PCT/KR2002/000509
申请日：2002-03-25
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , KIM, Hwan-Mook , HAN, Sang-Bae , LEE, Chang-Woo , LEE, Ki-Hoon , PARK, Se-Hyung , KIM, Hyoung-Chin , KIM, Young-Kook
发明人： KIM, Hwan-Mook , HAN, Sang-Bae , LEE, Chang-Woo , LEE, Ki-Hoon , PARK, Se-Hyung , KIM, Hyoung-Chin , KIM, Young-Kook
IPC分类号： A61K31/4025
CPC分类号： A61K31/4025
摘要： The present invention relates to novel use of prodigiosin for the treatment of Rheumatic arthritis and can provide excellent treatment effect to Rheumatic arthritis by treating composition including prodigiosin isolated from Serratia marcescence as an active principle to DBA-1 mouse of collagen-induced Rheumatic arthritis animal model and thereby inhibiting production of internal cytokine which is a important pathogen of Rheumatic arthritis.
摘要翻译：本发明涉及生殖细胞因子用于治疗风湿性关节炎的新用途，并且可以通过将组合物（包括从沙雷氏菌属分离得到的生殖细胞）作为活性成分处理组合物来提供对风湿性关节炎的优异治疗作用，以DBA-1小鼠胶原诱导的风湿性关节炎动物模型，从而抑制作为风湿性关节炎重要病原体的内部细胞因子的产生。

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