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1. 发明申请

WO2011132966A3 TRANSDERMAL ABSORPTION PREPARATION 审中-公开
标题翻译：超吸收制剂
公开(公告)号：WO2011132966A3
公开(公告)日：2012-04-12
申请号：PCT/KR2011002887
申请日：2011-04-21
申请人： ICURE PHARMACEUTICAL INC , CHOI YOUNG KWEON , KIM JUNG JU , KIM SEONG SU , LEE JUNG SIK , PARK SEONG MIN
发明人： CHOI YOUNG KWEON , KIM JUNG JU , KIM SEONG SU , LEE JUNG SIK , PARK SEONG MIN
IPC分类号： A61K9/70 , A61K31/404 , A61P25/00
CPC分类号： A61K9/7061 , A61K9/7053 , A61K9/7076 , A61K31/4045
摘要： The present invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallization agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial concentration in blood occurs and the skin penetration effect of the drug is excellent.
摘要翻译：本发明涉及透皮吸收制剂。本发明的透皮吸收制剂包含含药物的粘合剂层，药物保护层和剥离层，其中药物含有层含有罗哌尼罗或其盐，橡胶，赋形树脂，抗氧化剂，和透皮吸收促进剂。另外，本发明提供了含有药物的粘合剂层，药物保护层和剥离层的透皮吸收制剂，其中药物含有层含有罗哌尼罗或其盐，丙烯酸橡胶，抗结晶剂，和透皮吸收促进剂。当本发明的经皮吸收制剂用于治疗帕金森病或不宁腿综合征时，由于血液中初始浓度的增加而引起副作用，药物的皮肤渗透作用优异。

2. 发明申请

WO2009041789A3 NOVEL 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION, THERAPEUTIC AGENT FOR INFLAMMATORY DISEASE INDUCED BY SPC ACTIVITY CONTAINING 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMIN 审中-公开
标题翻译：新的3-氯-5-取代的喹喔啉-2-胺衍生物及其药学上可接受的盐，制备治疗由SPC活性引起的炎性疾病包含3-氯-5-取代的喹喔啉-2-胺的方法
公开(公告)号：WO2009041789A3
公开(公告)日：2009-05-14
申请号：PCT/KR2008005725
申请日：2008-09-26
申请人： KOREA RES INST CHEM TECH , AMOREPACIFIC CORP , GONG YOUNG-DAE , CHO HEEYEONG , JEON MOON-KOOK , LEE TAEHO , CHOI GILDON , KONG JAE-YANG , PARK WOO-KYU , HWANG SOON-HEE , KIM JUNG JU , LEE CHANG-HOON , KO JAEYOUNG , NOH MINSOO , HAN EUN SIL , KIM HYUK , YUN JUN-WON , MOH JOO HYUN , KIM DO HOON
发明人： GONG YOUNG-DAE , CHO HEEYEONG , JEON MOON-KOOK , LEE TAEHO , CHOI GILDON , KONG JAE-YANG , PARK WOO-KYU , HWANG SOON-HEE , KIM JUNG JU , LEE CHANG-HOON , KO JAEYOUNG , NOH MINSOO , HAN EUN SIL , KIM HYUK , YUN JUN-WON , MOH JOO HYUN , KIM DO HOON
IPC分类号： C07D401/12
CPC分类号： C07D401/12
摘要： Provided are a 3-chloro-5-substiuted-quinoxalin-2-amine derivative represented by the following Chemical Formula 1, a pharmaceutically acceptable salt thereof, a method for preparation thereof, and a use thereof as an effective ingredient in a therapeutic agent for inflammatory disease induced by activity of sphingosyl phosphorylcholine (SPC) receptor. The 3-chloro-5-substiuted-quinoxalin-2-amine derivative of the present invention has been confirmed to have superior inhibition activity against SPC receptor in an animal experiment using human-derived endothelial cells and mice. Thus, a therapeutic agent for inflammatory disease containing the 3- chloro-5-substiuted-quinoxalin-2-amine derivative or a pharmaceutically acceptable salt thereof as an effective ingredient may be useful for treating inflammation, itching or skin infection associated with atopic dermatitis or other disease induced by activity of SPC receptor.
摘要翻译：本发明提供由以下化学式1表示的3-氯-5-取代的喹喔啉-2-胺衍生物，其药学上可接受的盐，其制备方法及其作为有效成分在治疗剂中的用途由鞘氨醇磷酸胆碱（SPC）受体活性诱导的炎性疾病。已证实本发明的3-氯-5-取代的喹喔啉-2-胺衍生物在使用源于人的内皮细胞和小鼠的动物实验中对SPC受体具有优异的抑制活性。因此，含有3-氯-5-取代的喹喔啉-2-胺衍生物或其药学上可接受的盐作为有效成分的炎症性疾病治疗剂可用于治疗与特应性皮炎相关的炎症，发痒或皮肤感染或其他由SPC受体活性诱导的疾病。

3. 发明申请

WO2008120833A1 LCD HAVING WINDOW ENDOWED FRONT LIGHT FUNCTION 审中-公开
标题翻译：液晶显示器具有窗口前端的前光功能
公开(公告)号：WO2008120833A1
公开(公告)日：2008-10-09
申请号：PCT/KR2007/001600
申请日：2007-04-02
申请人： NAMOTEK CO., LTD. , HWANG, JANG HWAN , KIM, JUNG JU , HWANG, SEON WOOK , PARK, JUNG WOON
发明人： HWANG, JANG HWAN , KIM, JUNG JU , HWANG, SEON WOOK , PARK, JUNG WOON
IPC分类号： G02F1/1335 , G02F1/13357
CPC分类号： G02B6/0036 , G02B6/0038 , G02F2001/133616
摘要： Disclosed is a liquid crystal display (LCD) having a window endowed with a front light function. The LCD of the present invention comprises a liquid crystal panel; a reflection sheet disposed at a rear side of the liquid crystal panel to reflect light advancing through the liquid crystal panel to the front; and the window disposed in front of the liquid crystal panel and having front light function by including a plurality of reflection lens protrusions on a rear surface thereof for refracting incident light to advance the light nearly perpendicularly to the liquid crystal panel and advancing emitted light to the front.
摘要翻译：公开了具有具有前光功能的窗口的液晶显示器（LCD）。本发明的LCD包括液晶面板; 反射片，设置在所述液晶面板的后侧，以反射通过所述液晶面板前进的光; 并且通过在其后表面上包括多个反射透镜突起而设置在液晶面板的前面并具有前光功能的窗口用于折射入射光以将光近似垂直于液晶面板推进，并将发射的光前进到面前。

4. 发明申请

WO2008082118A1 APPARATUS AND METHOD FOR COMBINING RECEIVED SIGNAL CONSIDERING INTERFERENCE FOR EACH ANTENNA, APPARATUS AND METHOD FOR COMPUTING SYMBOL METRIC USING IT 审中-公开
标题翻译：用于组合接收信号的装置和方法考虑到每个天线的干扰，装置和使用其计算符号度量的方法
公开(公告)号：WO2008082118A1
公开(公告)日：2008-07-10
申请号：PCT/KR2007/006763
申请日：2007-12-21
申请人： POSDATA CO., LTD. , LEE, Dong-Kwan , KIM, Jung-Ju , KIM, Jae-Hyeong
发明人： LEE, Dong-Kwan , KIM, Jung-Ju , KIM, Jae-Hyeong
IPC分类号： H04B7/02
CPC分类号： H04B7/0851 , H04B17/26 , H04B17/345
摘要： Disclosed is an apparatus and method for combining a received signal considering interference for each antenna, and an apparatus and method for computing symbol metric using the same in a wireless communication system equipped with a plurality of transceiver antennas. The symbol metric calculation apparatus considering interference for each antenna comprises a channel estimator for receiving signals from the receive antenna, and estimating a channel by using a pilot signal of each signal received from the receive antenna; a noise and interference power estimator for receiving an output of the channel estimator, and estimating a noise and interference power of each channel; a combining unit for channel-compensating the channels estimated in the channel estimator and the noise and interference power estimated in the noise and interference power estimator, and combining the channel-compensated signals; a variance calculation unit for calculating a variance of data tone by using the ratio of the channel estimated in the channel estimator to a noise and interference estimated in the noise and interference power estimator; and a symbol metric calculation unit for calculates a symbol metric by using the variance calculated in the variance calculation unit and the signals combined in the combining unit.
摘要翻译：公开了一种考虑每个天线的干扰的接收信号的组合的装置和方法，以及一种在配备有多个收发天线的无线通信系统中使用该信号计算符号度量的装置和方法。考虑每个天线的干扰的符号度量计算装置包括用于从接收天线接收信号的信道估计器，并且通过使用从接收天线接收的每个信号的导频信号来估计信道; 噪声和干扰功率估计器，用于接收信道估计器的输出，并估计每个信道的噪声和干扰功率; 用于信道补偿在信道估计器中估计的信道的合成单元和在噪声和干扰功率估计器中估计的噪声和干扰功率，以及组合信道补偿信号; 方差计算单元，用于通过使用在信道估计器中估计的信道的比率与在噪声和干扰功率估计器中估计的噪声和干扰的比率来计算数据音调的方差; 以及符号度量计算单元，用于通过使用在方差计算单元中计算的方差和组合单元中组合的信号来计算符号度量。

5. 发明申请

WO2008082117A1 METHOD AND APPARATUS FOR ESTIMATING CARRIER TO INTERFERENCE AND NOISE RATIO 审中-公开
标题翻译：估计载波干扰和噪声比的方法和装置
公开(公告)号：WO2008082117A1
公开(公告)日：2008-07-10
申请号：PCT/KR2007/006762
申请日：2007-12-21
申请人： POSDATA CO., LTD. , LEE, Dong-Kwan , KIM, Jung-Ju
发明人： LEE, Dong-Kwan , KIM, Jung-Ju
IPC分类号： H04B7/26
CPC分类号： H04L1/206 , H04W24/00 , H04W48/08 , H04W48/16 , H04W52/0245 , Y02D70/146
摘要： The present invention relates to the method and apparatus for estimating a carrier to interference and noise ratio (CINR) in a wireless communication system. The apparatus for estimating a CINR includes a channel power estimator for calculating a channel power for an estimated channel value; a channel power differential calculation unit for calculating a differential power for a difference between a received pilot and the estimated channel value; a first CINR calculation unit for estimating a CINR of a channel by utilizing a ratio of the channel power calculated in the channel power estimator to the differential power calculated in the channel power differential calculation unit, when a signal to noise ratio (SNR) of the channel is smaller than a threshold value; and a second CINR calculation unit for estimating a CINR of the channel by utilizing a ratio of the channel power calculated in the channel power estimator to a value amending the differential power calculated in the channel power differential calculation unit with a residual value using an autocorrelation function, when the SNR is larger than the threshold value.
摘要翻译：本发明涉及无线通信系统中用于估计载波与干扰和噪声比（CINR）的方法和装置。用于估计CINR的装置包括用于计算估计信道值的信道功率的信道功率估计器; 信道功率差分计算单元，用于计算接收导频与估计信道值之差的差分功率; 第一CINR计算单元，用于通过利用在信道功率估计器中计算的信道功率与在信道功率差分计算单元中计算的差分功率的比率来估计信道的CINR，当信道功率估计器的信噪比（SNR）通道小于阈值; 以及第二CINR计算单元，用于通过利用在信道功率估计器中计算的信道功率的比率与修正在信道功率差分计算单元中计算的差分功率的值与使用自相关函数的残差值来估计信道的CINR 当SNR大于阈值时。

6. 发明申请

WO2008048043A1 USE OF SPHINGOSYLPHOSPHORYLCHOLINE MODULATOR FOR INHIBITING EXPRESSION OF CCL27/CTACK 审中-公开
标题翻译：用于抑制CCL27 / CTACK表达的磷脂酰胆碱调节剂的应用
公开(公告)号：WO2008048043A1
公开(公告)日：2008-04-24
申请号：PCT/KR2007/005080
申请日：2007-10-17
申请人： AMOREPACIFIC CORPORATION , KIM, Hyoung June , SUNG, Ki Sa , KIM, Hyuk , NOH, Min Soo , KO, Jae Young , KIM, Dae-Kwon , CHO, Sun A , KIM, Kwang Mi , LEE, Chang-Hoon , KIM, Jung Ju
发明人： KIM, Hyoung June , SUNG, Ki Sa , KIM, Hyuk , NOH, Min Soo , KO, Jae Young , KIM, Dae-Kwon , CHO, Sun A , KIM, Kwang Mi , LEE, Chang-Hoon , KIM, Jung Ju
IPC分类号： A61K31/047
CPC分类号： A61K31/047
摘要： Provided are a method of inhibiting the expression of CCL27/CTACK (cutaneous T-cell attracting chemokine) using a sphingosylphosphorylcholine (SPC) modulator, a use of an SPC modulator for the manufacture of a medicament for inhibiting the expression of CCL27/CTACK, and a method of screening for an SPC modulator candidate by measuring the suppression level of CCL27/CTACK expression for the purpose of curing diseases caused by overexpression of CCL27/CTACK, such as atopic dermatitis, psoriasis, and inflammatory skin diseases.
摘要翻译：提供了使用鞘氨醇磷酰胆碱（SPC）调节剂抑制CCL27 / CTACK（皮肤T细胞吸引趋化因子）表达的方法，SPC调节剂用于制造抑制CCL27 / CTACK表达的药物的用途，以及通过测量CCL27 / CTACK表达的抑制水平来治疗由过度表达CCL27 / CTACK引起的疾病如特应性皮炎，牛皮癣和炎性皮肤疾病的目的，筛选SPC调节剂候选物的方法。

7. 发明申请

WO2008013416A1 PROCESS FOR PREPARING POWDER COMPRISING NANOPARTICLES OF SPARINGLY SOLUBLE DRUG 审中-公开
标题翻译：制备包含可溶性药物纳米颗粒的粉末的方法
公开(公告)号：WO2008013416A1
公开(公告)日：2008-01-31
申请号：PCT/KR2007/003599
申请日：2007-07-26
申请人： AMOREPACIFIC CORPORATION , BAE, Joon Ho , LEE, Jong Hwi , LEE, Hyeok , KIM, Jung Ju
发明人： BAE, Joon Ho , LEE, Jong Hwi , LEE, Hyeok , KIM, Jung Ju
IPC分类号： A61K9/14
CPC分类号： A61K9/5123 , A61K9/0019 , A61K9/0095 , A61K9/145 , A61K9/146 , A61K9/5161 , A61K9/5192
摘要： A powder comprising nanoparticles of a sparingly water-soluble drug prepared in accordance with the present invention exhibits enhanced bioavailability without generating adverse side effects caused by impurities, while the nano-particle size of the drug remains unchanged when administered. Accordingly, the powder can be useful for the development of a formulation of a sparingly water-soluble drug for oral and parenteral administration.
摘要翻译：包含根据本发明制备的微水溶性药物的纳米颗粒的粉末表现出增强的生物利用度，而不产生由杂质引起的不良副作用，而药物的纳米粒度在施用时保持不变。因此，粉末可用于开发用于口服和肠胃外给药的微水溶性药物的制剂。

8. 发明申请

WO2013025061A4 METHOD FOR PREPARING NITROPARAFFIN BY GAS PHASE NITRATION 审中-公开
标题翻译：气相法制备硝酸盐的方法
公开(公告)号：WO2013025061A4
公开(公告)日：2013-07-18
申请号：PCT/KR2012006520
申请日：2012-08-16
申请人： KOREA RES INST CHEM TECH , KOREA KUMHO PETROCHEM CO LTD , KO SANG GIL , KIM JUNG JU , CHANG TAE SUN , KIM JIN EOK , ROH KEE YOON
发明人： KO SANG GIL , KIM JUNG JU , CHANG TAE SUN , KIM JIN EOK , ROH KEE YOON
IPC分类号： C07C201/08 , B01J21/06 , B01J27/199 , C07C205/06
CPC分类号： C07C201/08 , B01J21/063 , B01J21/066 , B01J23/06 , B01J23/10 , B01J23/26 , B01J23/28 , B01J23/30 , B01J27/12 , B01J27/19 , B01J27/199 , B01J37/0201 , C07C205/02
摘要： The present invention relates to a method for preparing nitroparaffin in high yield by reacting a hydrocarbon compound with a gas phase nitration agent using a specific solid acid catalyst, a solid base catalyst or a mixture thereof as a catalyst, wherein the method can: obtain a sufficiently high yield of nitroparaffin although the gas phase nitration is carried out in normal pressure conditions; and carry out the reaction through a continuous process as well as a batch-type process, such that the method is very useful as an industrial production method.
摘要翻译：本发明涉及使用特定固体酸催化剂，固体碱催化剂或其混合物作为催化剂使烃化合物与气相硝化剂反应以高产率制备硝基烷烃的方法，其中所述方法可以：获得尽管气相硝化在常压条件下进行，但是硝基石蜡的产率足够高; 并通过连续过程以及间歇式过程进行反应，使得该方法作为工业生产方法非常有用。

9. 发明申请

WO2009041789A2 NOVEL 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION, THERAPEUTIC AGENT FOR INFLAMMATORY DISEASE INDUCED BY SPC ACTIVITY CONTAINING 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AS AN EFFECTIVE INGREDIENT 审中-公开
标题翻译：新型3-氯代-5-取代的喹喔啉-2-胺衍生物及其药学上可接受的盐，其制备方法，由含有3-氯代 - 喹啉-2-胺的SPC活性诱导的炎症疾病的治疗剂
公开(公告)号：WO2009041789A2
公开(公告)日：2009-04-02
申请号：PCT/KR2008/005725
申请日：2008-09-26
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , AMOREPACIFIC CORPORATION , GONG, Young-Dae , CHO, Heeyeong , JEON, Moon-Kook , LEE, Taeho , CHOI, Gildon , KONG, Jae-Yang , PARK, Woo-Kyu , HWANG, Soon-Hee , KIM, Jung Ju , LEE, Chang-hoon , KO, Jaeyoung , NOH, Minsoo , HAN, Eun Sil , KIM, Hyuk , YUN, Jun-Won , MOH, Joo Hyun , KIM, Do Hoon
发明人： GONG, Young-Dae , CHO, Heeyeong , JEON, Moon-Kook , LEE, Taeho , CHOI, Gildon , KONG, Jae-Yang , PARK, Woo-Kyu , HWANG, Soon-Hee , KIM, Jung Ju , LEE, Chang-hoon , KO, Jaeyoung , NOH, Minsoo , HAN, Eun Sil , KIM, Hyuk , YUN, Jun-Won , MOH, Joo Hyun , KIM, Do Hoon
IPC分类号： C07D401/12
CPC分类号： C07D401/12
摘要： Provided are a 3-chloro-5-substiuted-quinoxalin-2-amine derivative represented by the following Chemical Formula 1, a pharmaceutically acceptable salt thereof, a method for preparation thereof, and a use thereof as an effective ingredient in a therapeutic agent for inflammatory disease induced by activity of sphingosyl phosphorylcholine (SPC) receptor. The 3-chloro-5-substiuted-quinoxalin-2-amine derivative of the present invention has been confirmed to have superior inhibition activity against SPC receptor in an animal experiment using human-derived endothelial cells and mice. Thus, a therapeutic agent for inflammatory disease containing the 3- chloro-5-substiuted-quinoxalin-2-amine derivative or a pharmaceutically acceptable salt thereof as an effective ingredient may be useful for treating inflammation, itching or skin infection associated with atopic dermatitis or other disease induced by activity of SPC receptor.
摘要翻译：本发明提供由以下化学式1表示的3-氯-5-取代喹喔啉-2-胺衍生物，其药学上可接受的盐，其制备方法及其作为治疗剂的有效成分的用途由鞘氨醇磷酰胆碱（SPC）受体活性引起的炎性疾病。在使用人源性内皮细胞和小鼠的动物实验中，已经证实本发明的3-氯-5-取代喹喔啉-2-胺衍生物对SPC受体具有优异的抑制活性。因此，含有3-氯-5-取代的喹喔啉-2-胺衍生物或其药学上可接受的盐作为有效成分的炎性疾病治疗剂可用于治疗与特应性皮炎相关的炎症，瘙痒或皮肤感染或其他由SPC受体活性引起的疾病。

10. 发明申请

WO2008048076A1 A COMPOSITION FOR TREATMENT OF ATOPIC DERMATITIS COMPRISING GLUCOSAMINE AND DERIVATIVES THEREOF AND A METHOD FOR TREATMENT OF ATOPIC DERMATITIS USING THEM 审中-公开
标题翻译：用于治疗包含葡萄糖胺及其衍生物的原发性皮肤病的组合物和使用它们治疗原发性皮肤病的方法
公开(公告)号：WO2008048076A1
公开(公告)日：2008-04-24
申请号：PCT/KR2007/005156
申请日：2007-10-19
申请人： AMOREPACIFIC CORPORATION , KIM, Soo-youl , SUNG, Ki sa , KIM, Hyoung June , KIM, Hyuk , KIM, Dae-kwon , CHO, Sun A , KIM, Kwang Mi , LEE, Chang-hoon , KIM, Jung Ju
发明人： KIM, Soo-youl , SUNG, Ki sa , KIM, Hyoung June , KIM, Hyuk , KIM, Dae-kwon , CHO, Sun A , KIM, Kwang Mi , LEE, Chang-hoon , KIM, Jung Ju
IPC分类号： A61K31/7028
CPC分类号： A61K31/7028
摘要： Disclosed herein is a novel use of glucosamine or a derivative thereof. A pharmaceutical composition for treating atopic dermatitis comprising glucosamine or a derivative thereof and a method of treating atopic dermatitis using the composition are disclosed. The pharmaceutical composition and the method realize the safe treatment of atopic dermatitis without the side effects associated with conventional anti-inflammatory drugs.
摘要翻译：本文公开了葡糖胺或其衍生物的新用途。公开了一种用于治疗包含葡糖胺或其衍生物的特应性皮炎的药物组合物和使用该组合物治疗特应性皮炎的方法。该药物组合物和方法实现了与常规抗炎药相关的副作用的特应性皮炎的安全治疗。

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