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    • 7. 发明申请
    • EDIBLE COMPOSITIONS CAPABLE OF REMOVING ORAL BIOFILM
    • 可食用组合物可以去除口腔生物膜
    • WO2003059302A1
    • 2003-07-24
    • PCT/IL2003/000001
    • 2003-01-01
    • YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEMSTEINBERG, DoronKAMYSHNY, AlexanderMAGDASSI, Shlomo
    • STEINBERG, DoronKAMYSHNY, AlexanderMAGDASSI, Shlomo
    • A61K7/16
    • A23G1/44A23G1/325A23G1/40A23G3/362A23G3/42A23G3/44A23G4/064A23G4/10A23G4/14A23G9/325A23G9/34A23G9/38A61K8/73A61K8/731A61K8/732A61K8/733A61K8/736A61K2800/5424A61Q11/00
    • An edible and/or chewable article of manufacture containing at least one food grade substance having adsorption affinity towards at least one dental plaque (biofilm) constituent and capable of reducing and/or removing the oral biofilm while present in the mouth. Particular articles of manufacture are chewing gums, sweets, candies, candy- and other nutritional bars, ice creams, chocolates, confectionery and bakery/pastry products, honey, dairy products and beverages, and oral hygiene products such as tooth pastes, oral gels and mouthwashes.A chewing gum comprises a conventional gum base and at least one food grade active substance having adsorption affinity towards at least one dental plaque (biofilm) constituent (bacteria and proteins and bacterial cell-free enzymes) and capable of reducing and/or removing the oral biofilm while present in the mouth.Typical active substances are polysaccharides and non-toxic salts thereof, such as alginates, chitosan, carboxymethylcellulose, agar and carrageenan, inorganic substances such as silica, hydroxyapatite and calcium carbonate and proteins, particularly gelatin and lectin.The chewing gum and other articles of manufacture are particularly intended for removing and/or for preventing or reducing dental plaque (biofilm), and controlling oral, dental and periodontal diseases.
    • 包含至少一种对至少一种牙菌斑(生物膜)成分具有吸附亲和力的食品级物质,并且能够在口腔中同时还原和/或除去口腔生物膜的食用和/或咀嚼制品。 特殊的制品是口香糖,糖果,糖果,糖果和其他营养棒,冰淇淋,巧克力,糖果和面包/糕点产品,蜂蜜,乳制品和饮料,以及口腔卫生产品如牙膏,口腔凝胶和 咀嚼口香糖包括常规胶基和至少一种对至少一种牙菌斑(生物膜)组分(细菌和蛋白质和细菌无细胞酶)具有吸附亲和力并且能够还原和/或去除的食品级活性物质 口腔生物膜同时存在于口腔中。典型活性物质是多糖和无毒盐,如藻酸盐,壳聚糖,羧甲基纤维素,琼脂和角叉菜胶,无机物质如二氧化硅,羟基磷灰石和碳酸钙和蛋白质,特别是明胶和凝血素 口香糖和其他制品特别用于去除和/或预防或减少牙齿p laque(生物膜),并控制口腔,牙科和牙周病。