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1. 发明申请

WO1987005225A2 PRESSURE-MEASUREMENT FLOW CONTROL SYSTEM 审中-公开
标题翻译：压力测量流量控制系统
公开(公告)号：WO1987005225A2
公开(公告)日：1987-09-11
申请号：PCT/US1987000515
申请日：1987-03-04
申请人： KAMEN, Dean, L.
IPC分类号： A61M05/14
CPC分类号： F16K31/005 , A61M5/16809 , A61M5/16813 , A61M5/16859 , A61M5/365 , A61M39/26 , A61M2005/1403 , A61M2205/15 , F04B43/043 , G01F11/086 , G01P13/0066 , Y10S128/12 , Y10S128/13 , Y10T137/7782 , Y10T137/7796 , Y10T137/88005
摘要： A system for controlling flow of a first fluid through a line (14). Dispensing means (131, 132, 141) isolates a region (141) of the first fluid in the line (14) from effects of pressure in the line (14) outside of the region (141). The dispensing means (131, 132, 141) repetitively dispenses increments of first fluid into and out of the region (141). Measurement fluid is housed (13) in communication with the region (141) such that the dispensing of increments of first fluid into or out of the region (141) causes a change in the measurement fluid pressure. Displacement means (161, 162) displaces a predetermined volume increment of measurement fluid into and out of the measurement fluid housing (13), such that displacement of the predetermined volume increment causes a change in the measurement fluid pressure when the region is isolated by the dispensing means (131, 132, 141). Pressure measurement means (15) changes in the measurement fluid pressure. Control means (81) in communication with the pressure measurement means (15), the displacement means (161, 162), and the dispensing means (131, 132, 141), causes the dispensing means (131, 132, 141) to dispense first fluid in increments based on data from the pressure measurement means (15), such that at least one one of the predetermined volume increments of measurement fluid displaced serves as a reference for the volume increments of first fluid outputted.
摘要翻译：一种用于控制通过管线（14）的第一流体的流动的系统。分配装置（131,132,141）将管线（14）中的第一流体的区域（141）与区域（141）外部的管线（14）中的压力的影响隔离。分配装置（131,132,141）重复地分配进入和离开区域（141）的第一流体的增量。测量流体被容纳（13）与区域（141）连通，使得将第一流体的增量分配到区域（141）中或从区域（141）中分配导致测量流体压力的变化。位移装置（161,162）将测量流体的预定体积增量移入和移出测量流体壳体（13），使得当该区域被隔离区域时，预定体积增量的位移导致测量流体压力的变化分配装置（131,132,141）。压力测量装置（15）改变了测量流体的压力。与压力测量装置（15），移动装置（161,162）和分配装置（131,132,141）连通的控制装置（81）使得分配装置（131,132,141）分配基于来自压力测量装置（15）的数据的第一流体以增量计量，使得所测量流体的预定体积增量中的至少一个位移用作输出的第一流体的体积增量的参考。

2. 发明申请

WO1987005223A1 INTRAVENOUS LINE VALVING SYSTEM 审中-公开
标题翻译：内部线性阀门系统
公开(公告)号：WO1987005223A1
公开(公告)日：1987-09-11
申请号：PCT/US1987000511
申请日：1987-03-03
申请人： KAMEN, Dean, L.
IPC分类号： A61M05/14
CPC分类号： F16K31/005 , A61M5/16809 , A61M5/16813 , A61M5/16859 , A61M5/365 , A61M39/26 , A61M2005/1403 , A61M2205/15 , F04B43/043 , G01F11/086 , G01P13/0066 , Y10S128/12 , Y10S128/13 , Y10T137/7782 , Y10T137/7796 , Y10T137/88005
摘要： An intravenous line valving system. A fitting (75) for attaching an intravenous line to a drip chamber (71) is equipped with an aperture (61) through the exterior of the fitting permitting communication with the intravenous fluid path. A fluidtight member over the aperture prevents leakage of intravenous fluid and means are provided for compressing the flexible member against the interior surface of the fitting so as to regulate the flow of intravenous fluid through the line. In a preferred embodiment, the flexible member is compressed by an actuating pin on a medical infusion controller. In a further preferred embodiment, the compression of the membrane is accomplished by advancing a screw (73) in a removable screw holder (72) that seats snugly around the fitting proximate to the aperture.
摘要翻译：一种静脉注管系统。用于将静脉内管线附接到滴水室（71）的配件（75）配备有通过允许与静脉内流体路径连通的配件的外部的孔（61）。孔上面的流体密封构件防止静脉内流体的泄漏，并且提供用于将柔性构件压靠在配件的内表面上的装置，以便调节通过管线的静脉内流体的流动。在优选实施例中，柔性构件由医用输注控制器上的致动销压缩。在另一优选实施例中，膜的压缩通过将螺钉（73）推进在靠近孔径的靠近配件的可移除螺钉保持器（72）中来实现。

3. 发明申请

WO1987005224A1 INFILTRATION DETECTION SYSTEM USING PRESSURE MEASUREMENT 审中-公开
标题翻译：使用压力测量的渗透检测系统
公开(公告)号：WO1987005224A1
公开(公告)日：1987-09-11
申请号：PCT/US1987000514
申请日：1987-03-04
申请人： KAMEN, Dean, L.
IPC分类号： A61M05/14
CPC分类号： F16K31/005 , A61M5/16809 , A61M5/16813 , A61M5/16859 , A61M5/365 , A61M39/26 , A61M2005/1403 , A61M2205/15 , F04B43/043 , G01F11/086 , G01P13/0066 , Y10S128/12 , Y10S128/13 , Y10T137/7782 , Y10T137/7796 , Y10T137/88005
摘要： A system for detecting the presence of infiltration of fluid being delivered through a line (14) to a patient (12). Stepping means (161, 163, 162, 17) subjects the fluid in the line (14) to a negative pressure step. Pressure monitoring means (15) monitors fluid pressure in the line (14). Processing means (18), in communication with the pressure monitoring means (15) and the stepping means (161, 162, 163, 17) activates the stepping means (161, 162, 163, 17) and determines whether the function of line pressure over time in response to the occurence of a negative pressure step (21, 22) exhibits a relatively slow return (22) to the pre-step pressure, such relatively slow return (22) being characteristic of the presence of infiltration.
摘要翻译：一种用于检测通过管线（14）输送到患者（12）的流体的渗透的存在的系统。步进装置（161,163,162,17）使管线（14）中的流体承受负压步骤。压力监测装置（15）监测管线（14）中的流体压力。与压力监测装置（15）和步进装置（161,162,163,17）连通的处理装置（18）启动步进装置（161,162,163,17），并确定线路压力的功能响应于负压步骤（21,22）的发生，随着时间的推移表现出相对较慢的返回（22）到前置压力，这种相对较慢的返回（22）是存在渗透的特征。

4. 发明申请

WO1982003554A1 FLUID FLOW CONTROL SYSTEM 审中-公开
标题翻译：流体流量控制系统
公开(公告)号：WO1982003554A1
公开(公告)日：1982-10-28
申请号：PCT/US1982000436
申请日：1982-04-09
申请人： KAMEN DEAN L
IPC分类号： A61M05/00
CPC分类号： G05D7/0635 , A61M5/16895 , G01G17/06 , Y10S128/13
摘要： A fluid flow control system includes a weight detector (12), for generating a weight measurement signal that is indicative of the weight of fluid in a reservoir (11); an adjustable reference generator (14) for generating a weight reference signal that is indicative of the desired rate of decrease in weight of the fluid in the reservoir (11); and a comparator (13) that produces an output indicative of the dissimilarity between the weight measurement and the weight reference signals. In a preferred embodiment, a drop counter (21) is placed in the line of flow (16) from the reservoir (11). The drop counter (21) produces an actual drop rate signal. There is also provided a device (22) that generates a programmed drop rate signal. The programmed drop rate signal is modified by the previously described comparator's output to produce a corrected drop rate signal. The actual and the corrected drop rate signals are directed to a second comparator (23) that operates on a flow controller (15).
摘要翻译：流体流量控制系统包括重量检测器（12），用于产生指示储存器（11）中流体重量的重量测量信号; 可调参考发生器（14），用于产生指示所述储存器（11）中流体的所需减重速度的重量参考信号; 以及比较器（13），其产生指示所述权重测量和所述权重参考信号之间的不相似性的输出。在优选实施例中，液滴计数器（21）从储存器（11）放置在流动线（16）中。液滴计数器（21）产生实际的液滴率信号。还提供了一种产生编程的丢失率信号的装置（22）。通过前述比较器的输出修改编程的丢弃率信号，以产生校正的丢弃率信号。实际和校正的丢失率信号被引导到在流量控制器（15）上操作的第二比较器（23）。

5. 发明申请

WO1989001795A1 ENHANCED PRESSURE MEASUREMENT FLOW CONTROL SYSTEM 审中-公开
标题翻译：增强压力测量流量控制系统
公开(公告)号：WO1989001795A1
公开(公告)日：1989-03-09
申请号：PCT/US1988003079
申请日：1988-09-01
申请人： KAMEN, Dean, L.
IPC分类号： A61M05/00
CPC分类号： A61M5/16813 , A61M5/16809 , A61M5/16859 , A61M5/365 , A61M39/26 , A61M2005/1403 , A61M2205/15 , F04B43/043 , F16K31/005 , G01F1/34 , G01P13/0066 , Y10S128/13
摘要： The present invention provides a system for measuring flow of a fluid through a line. In the system, a region (15) of fluid along the line is isolated from pressure effects outside of the region. A source region (12) contains a measurement gas in communication with the isolated region, such that the source means and the isolated region together define a fixed volume, and such that a change in volume of fluid in the isolated region produces a complementary change in the volume of the source means with a resulting change in the pressure of the measurement gas contained in the source region. Further provided is a reservoir (11) in communication with the source means for containing a known volume of measurement gas, and means (25) for pumping measurement gas from the reservoir. The pressure of the measurement gas in the reservoir and the source region is monitored. This pressure data is then analyzed to determine the volume of fluid in the isolated region.
摘要翻译：本发明提供一种用于测量通过管线的流体流动的系统。在该系统中，沿该线的流体区域（15）与该区域外的压力效应隔离。源区域（12）包含与隔离区域连通的测量气体，使得源装置和隔离区域一起限定固定体积，并且使得隔离区域中的流体的体积变化产生互补变化源的体积意味着源区域中包含的测量气体的压力的变化。还提供了一种与源装置连通的用于容纳已知体积的测量气体的储存器（11），以及用于从储存器抽取测量气体的装置（25）。监测储层和源区中测量气体的压力。然后分析该压力数据以确定分离区域中的流体体积。

6. 发明申请

WO1987007161A1 DROP DETECTION HOUSING WITH POSITIVE TACTILE SIGNALING 审中-公开
标题翻译：具有正向触觉信号的检测外壳
公开(公告)号：WO1987007161A1
公开(公告)日：1987-12-03
申请号：PCT/US1987001207
申请日：1987-05-28
申请人： KAMEN, Dean, L.
IPC分类号： A61M05/16
CPC分类号： A61M5/1689 , A61M2205/6036
摘要： A system is provided for the automatic, self-checking switching of a medical infusion controller among a plurality of modes of operation. A medical infusion controller has a plurality of pressure-sensitive switches (37, 38), each of which corresponds to a different mode of operation. A drip chamber (11) is provided with nub elements (14) in one of a variety of possible configurations each of which correspond to one of the pressure-sensitive switches (37, 38) on the controller. When the drip chamber (11) is placed in the controller, the nub configuration activates the corresponding switch (37, 38). If the controller detects an incorrect number of nubs (14), it delivers an error message.
摘要翻译：提供了一种用于在多种操作模式中的医用输液控制器的自动，自检切换的系统。医用输液控制器具有多个压敏开关（37,38），每个压敏开关对应于不同的操作模式。滴水室（11）设置有多个可能构造中的一种，其中的多个元件（14）对应于控制器上的压敏开关（37,38）之一。当滴水室（11）放置在控制器中时，母线配置激活相应的开关（37,38）。如果控制器检测到不正确的数组（14），则会传递错误消息。

7. 发明申请

WO8705225A3 PRESSURE-MEASUREMENT FLOW CONTROL SYSTEM 审中-公开
标题翻译：压力测量流量控制系统
公开(公告)号：WO8705225A3
公开(公告)日：1987-11-19
申请号：PCT/US8700515
申请日：1987-03-04
申请人： KAMEN DEAN L
发明人： KAMEN DEAN L
IPC分类号： A61M5/00 , A61M5/14 , A61M5/168 , A61M5/36 , A61M39/26 , F04B43/02 , F04B43/04 , F04B43/067 , F04B49/06 , F16K31/00 , G01P13/00
CPC分类号： F16K31/005 , A61M5/16809 , A61M5/16813 , A61M5/16859 , A61M5/365 , A61M39/26 , A61M2005/1403 , A61M2205/15 , F04B43/043 , G01F11/086 , G01P13/0066 , Y10S128/12 , Y10S128/13 , Y10T137/7782 , Y10T137/7796 , Y10T137/88005
摘要： A system for controlling flow of a first fluid through a line (14). Dispensing means (131, 132, 141) isolates a region (141) of the first fluid in the line (14) from effects of pressure in the line (14) outside of the region (141). The dispensing means (131, 132, 141) repetitively dispenses increments of first fluid into and out of the region (141). Measurement fluid is housed (13) in communication with the region (141) such that the dispensing of increments of first fluid into or out of the region (141) causes a change in the measurement fluid pressure. Displacement means (161, 162) displaces a predetermined volume increment of measurement fluid into and out of the measurement fluid housing (13), such that displacement of the predetermined volume increment causes a change in the measurement fluid pressure when the region is isolated by the dispensing means (131, 132, 141). Pressure measurement means (15) changes in the measurement fluid pressure. Control means (81) in communication with the pressure measurement means (15), the displacement means (161, 162), and the dispensing means (131, 132, 141), causes the dispensing means (131, 132, 141) to dispense first fluid in increments based on data from the pressure measurement means (15), such that at least one one of the predetermined volume increments of measurement fluid displaced serves as a reference for the volume increments of first fluid outputted.

8. 发明申请

WO1985002774A1 CATHETER STABILIZATION PAD 审中-公开
标题翻译：过滤器稳定垫
公开(公告)号：WO1985002774A1
公开(公告)日：1985-07-04
申请号：PCT/US1984001852
申请日：1984-11-08
申请人： KAMEN, Dean, L.
IPC分类号： A61M05/00
CPC分类号： G11C5/145 , A61M5/158 , A61M25/02 , A61M2025/0213 , A61M2025/0286 , Y10S128/26
摘要： A unitary sheet device (1) for removably securing a catheter (6) to the skin of a patient includes a pair of flaps (3) for being affixed to the skin and a central portion (4) preformed in a contour conforming to the catheter hub. When affixed, the central portion (4) and the patient's skin together form a receptacle for securely holding the catheter against movement. The central portion (4) may be a tapered conical sheet and the flaps (3) may have adhesive for ease of attachment. A detent (8, 21) is provided, which may include a hole (8) through the central portion (4) of the sheet for engaging a protruding hub (21) from the catheter hub. Flexing of the sheet disengages the detent elements (8, 21). A non-adhesive tab (5) on one flap (3) aids in removing the device (1).

9. 发明申请

WO1985002256A1 VOLUMETRIC PUMP WITH REPLACEABLE RESERVOIR ASSEMBLY 审中-公开
标题翻译：具有可更换储存器组件的容积泵
公开(公告)号：WO1985002256A1
公开(公告)日：1985-05-23
申请号：PCT/US1984001841
申请日：1984-11-08
申请人： KAMEN, Dean, L.
IPC分类号： G01N01/14
CPC分类号： A61M5/1456 , A61M2005/14573 , Y10S128/12
摘要： An infusion pump has a removable reservoir including a piston (13) and drive member (12). The drive member is an internally threaded elongated portion of the piston. A motor rotates a short drive screw (14), which engages the threads of the drive member to displace the piston in the reservoir (11). In one embodiment the piston (13) is attached to the drive member (12) by a severable central stem (131) which breaks away to allow engagement with the drive screw. With the stem severed, the piston (13) cannot be retracted, or the reservoir (11) refilled. Other safety features are shown for locking the displaced piston (13) in the reservoir (11). A digital metering system has a safety circuit to prevent dangerous failure modes of the rotation sensor and motor drive systems.

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