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1. 发明申请

WO2011145909A3 NOVEL USE OF PANDURATIN DERIVATIVES OR AN EXTRACT OF BOESENBERGIA PANDURATA FOR PROMOTING MUSCLE MASS GROWTH, FIGHTING FATIGUE, AND ENHANCING EXERCISE PERFORMANCE CAPABILITY 审中-公开
标题翻译：潘多拉汀衍生物的新用途或提取物，用于促进肌肉大量生长，消除疲劳和增强锻炼性能能力
公开(公告)号：WO2011145909A3
公开(公告)日：2012-03-29
申请号：PCT/KR2011003735
申请日：2011-05-20
申请人： BIOCARE CO LTD , NEWTREE CO LTD , HWANG JAE-KWAN , KIM DO UN
发明人： HWANG JAE-KWAN , KIM DO UN
IPC分类号： A61K31/05 , A61K36/906 , A61P21/00 , A61P43/00
CPC分类号： A61K36/906 , A23L33/105 , A61K31/12 , A61K36/00
摘要： The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for promoting muscle mass growth, fighting fatigue, and enhancing exercise performance capability. More particularly, the present invention relates to a composition for enhancing exercise performance capability, promoting muscle mass growth, and fighting fatigue, which comprises panduratin derivatives or salts thereof, or an extract of Boesenbergia pandurata, as active ingredients, and which promotes muscle mass growth and recovery from fatigue to improve mobility. The present invention also relates to a method for improving exercise performance capability, promoting muscle mass growth, and fighting fatigue, which involves injecting panduratin derivatives or salts thereof, or an extract of Boesenbergia pandurata, into an individual requiring same. The panduratin derivatives or the extract of Boesenbergia pandurata of the present invention can be used safely with no adverse effects, and increases the expression of PPAR d in the muscles, thus exhibiting excellent effects in promoting muscle mass growth, recovery from fatigue, and an enhancement in exercise performance capability such as an enhancement in mobility.
摘要翻译：本发明涉及潘多蛋白衍生物或泛黄柏提取物的新用途，用于促进肌肉生长，抗疲劳，提高运动能力。更具体地，本发明涉及一种用于增强运动性能能力，促进肌肉量增长和抗疲劳的组合物，其包含潘多汀衍生物或其盐，或作为活性成分的Boesenbergia pandurata的提取物，并且其促进肌肉质量生长并从疲劳中恢复，提高流动性。本发明还涉及一种用于提高运动能力，促进肌肉量增长和抗疲劳的方法，其包括将潘多蛋白衍生物或其盐，或Boesenbergia pandurata的提取物注射到需要相同的个体中。可以安全地使用本发明的潘氏白藜芦素衍生物或提取物，没有副作用，并且增加肌肉中PPAR d的表达，因此在促进肌肉量生长，疲劳恢复和增强方面表现出优异的效果在运动表现能力，如增加流动性。

2. 发明申请

WO2008156345A3 USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT 审中-公开
标题翻译： LIGNAN化合物用于抗皱治疗的用途
公开(公告)号：WO2008156345A3
公开(公告)日：2009-03-12
申请号：PCT/KR2008003547
申请日：2008-06-20
申请人： BIOCARE CO LTD , HWANG JAE-KWAN , LEE HAE JI , LEE JAE YOUNG , SHIM JAE-SEOK , KIM JEONG HWAN
发明人： HWANG JAE-KWAN , LEE HAE JI , LEE JAE YOUNG , SHIM JAE-SEOK , KIM JEONG HWAN
IPC分类号： A61K8/34
CPC分类号： A61K8/97 , A61K8/347 , A61K8/498 , A61Q19/08
摘要： The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme- 1(MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.
摘要翻译：本发明涉及木糖素化合物的新用途，其从肉豆蔻或肉豆蔻的肠道中分离和纯化用于抗皱，更具体地，本发明涉及用于抗皱的提取物的抗皱纹的新用途肉豆蔻或肉豆蔻，fragrin A，奥维菌素7，licarin E和肉豆蔻衣木脂的提取物。本发明的提取物和木脂素化合物具有抑制胶原降解酶-1（MMP-1，基质金属蛋白酶-1）和新型胶原（1型前胶原）的形成的作用，从而具有抑制由光老化。因此，本发明的提取物和木酚素化合物可用于预防或治疗由光老化引起的皱纹。

3. 发明申请

WO2006104369A1 NOVEL USE OF LIGNAN COMPOUNDS 审中-公开
标题翻译：使用LIGNAN化合物的新用途
公开(公告)号：WO2006104369A1
公开(公告)日：2006-10-05
申请号：PCT/KR2006/001212
申请日：2006-03-31
申请人： INJE UNIVERSITY , HWANG, Jae-Kwan , HAN, Jung-Soo , LIM, Chol-Seung , JIN, Daqing , LEE, Sun-Hee , HAN, Kyu-Lee
发明人： HWANG, Jae-Kwan , HAN, Jung-Soo , LIM, Chol-Seung , JIN, Daqing , LEE, Sun-Hee , HAN, Kyu-Lee
IPC分类号： A61K31/357
CPC分类号： A61K36/185 , A61K31/357
摘要： The present invention relates to the novel use of lignan compounds represented by Formula I. More particularly, the present invention relates to a pharmaceutical composition for treating or preventing a brain disease, comprising a lignan compound represented by Formula I or a Myristica fragrans extract as an active ingredient, as well as the method and use for treating or preventing a brain disease using the lignan compound. The lignan compound represented by Formula I has the effects of antioxidation, brain cell protection and antiinflammation. Accordingly, said lignan compound will be highly useful for treating or preventing a brain disease.
摘要翻译：本发明涉及由式I表示的木酚素化合物的新用途。更具体地，本发明涉及用于治疗或预防脑疾病的药物组合物，其包含由式I表示的木酚素化合物或肉豆蔻酸提取物作为活性成分，以及用于使用木脂素化合物治疗或预防脑部疾病的方法和用途。由式I表示的木酚素化合物具有抗氧化，脑细胞保护和抗炎的作用。因此，所述木脂素化合物对于治疗或预防脑部疾病是非常有用的。

4. 发明申请

WO03097000A8 COMPOSITION FOR ENHANCING ORAL HEALTH 审中-公开
标题翻译：用于增强口腔健康的组合物
公开(公告)号：WO03097000A8
公开(公告)日：2005-07-21
申请号：PCT/KR0300979
申请日：2003-05-16
申请人： LG HOUSEHOLD & HEALTH CARE LTD , HWANG JAE KWAN , KIM HYUNG-JIN , KIM SANG-NYUN , KIM HOO-DEOK , KIM YOUNG-HO , KIM MOON-MOO , PARK HYOUNG-KOOK
发明人： KIM HYUNG-JIN , KIM SANG-NYUN , KIM HOO-DEOK , KIM YOUNG-HO , KIM MOON-MOO , PARK HYOUNG-KOOK
IPC分类号： A61K8/00 , A61K8/34 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/97 , A61K36/9066 , A61K45/06 , A61Q11/00 , A61K7/16
CPC分类号： A61K8/97 , A61K8/347 , A61K8/42 , A61K8/44 , A61K8/463 , A61K8/466 , A61K36/9066 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要： Disclosed is composition for enhancing oral health, which includes 0.0001~10 wt % of Xanthorrhizol on the basis of the total weight of the composition, and 0.01~10 wt % of at least one antibacterial activity enhancer selected form the group consisting of alkyl sodium sulfate, sodium lauroyl sarcocinate and sodium methylcocoyltaurate. The antibacterial activity enhancer contained in the composition more effectively enhances antibacterial activity of Xanthorrhizol against causative bacterial of a decayed tooth or a peridental disease existing in the mouth, so the composition is very helpful for enhancing the oral health, for example the prevention or relief of a decayed tooth or a peridental disease or the restraint of foul breath.
摘要翻译：公开了用于提高口腔健康的组合物，其包含基于组合物总重量的0.0001〜10重量％的Xanthorrhizol，以及选自烷基硫酸钠的0.01〜10重量％的至少一种抗菌活性增强剂月桂酰肌氨酸钠和甲基胆甾烯酸月桂酸钠。组合物中所含的抗菌活性增强剂更有效地增加了Xanthorrhizol对口腔中存在的腐烂性牙齿或外来疾病的致病菌的抗菌活性，因此该组合物对于提高口腔健康有非常有益的作用，例如预防或缓解蛀牙或外伤性疾病或窒息呼吸的限制。

5. 发明申请

WO2003097000A1 COMPOSITION FOR ENHANCING ORAL HEALTH 审中-公开
标题翻译：用于增强口腔健康的组合物
公开(公告)号：WO2003097000A1
公开(公告)日：2003-11-27
申请号：PCT/KR2003/000979
申请日：2003-05-16
申请人： LG HOUSEHOLD & HEALTHCARE CO., LTD. , HWANG, Jae-Kwan , KIM, Hyung-Jin , KIM, Sang-Nyun , KIM, Hoo-Deok , KIM, Young-Ho , KIM, Moon-Moo , PARK, Hyoung-Kook
发明人： KIM, Hoo-Deok , KIM, Young-Ho , KIM, Moon-Moo , PARK, Hyoung-Kook
IPC分类号： A61K7/16
CPC分类号： A61K8/97 , A61K8/347 , A61K8/42 , A61K8/44 , A61K8/463 , A61K8/466 , A61K36/9066 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要： Disclosed is composition for enhancing oral health, which includes 0.0001∼10 wt % of Xanthorrhizol on the basis of the total weight of the composition, and 0.01∼10 wt % of at least one antibacterial activity enhancer selected form the group consisting of alkyl sodium sulfate, sodium lauroyl sarcocinate and sodium methylcocoyltaurate. The antibacterial activity enhancer contained in the composition more effectively enhances antibacterial activity of Xanthorrhizol against causative bacterial of a decayed tooth or a peridental disease existing in the mouth, so the composition is very helpful for enhancing the oral health, for example the prevention or relief of a decayed tooth or a peridental disease or the restraint of foul breath.
摘要翻译：公开了用于提高口腔健康的组合物，其包含基于组合物总重量的0.0001〜10重量％的Xanthorrhizol，以及选自烷基硫酸钠的0.01〜10重量％的至少一种抗菌活性增强剂月桂酰肌氨酸钠和甲基胆甾烯酸月桂酸钠。组合物中所含的抗菌活性增强剂更有效地提高了Xanthorrhizol对存在于口腔中的腐烂性牙齿或外来疾病的致病菌的抗菌活性，因此该组合物对于提高口腔健康状况非常有帮助，例如预防或缓解蛀牙或外伤性疾病或窒息呼吸的限制。

6. 发明申请

WO2012099449A3 NOVEL USE OF FLAVONE-BASED COMPOUND 审中-公开
标题翻译：使用基于FLAVONE的化合物的新用途
公开(公告)号：WO2012099449A3
公开(公告)日：2012-12-06
申请号：PCT/KR2012000601
申请日：2012-01-25
申请人： INDUSTRY ACADEMIC COOPERATION , HWANG JAE-KWAN , KIM JAEKYUNG
发明人： HWANG JAE-KWAN , KIM JAEKYUNG
IPC分类号： A61K8/49 , A61K8/97 , A61K31/352 , A61Q19/00
CPC分类号： A61K8/498 , A23G3/48 , A23G4/068 , A23L2/52 , A23L33/105 , A61K8/97 , A61K31/352 , A61Q19/007 , A61Q19/08
摘要： The present invention relates to a novel use of a flavone-based compound or Kaempferia parviflora extract, and more particularly, to a composition for anti-wrinkle, anti-aging and improvement of skin elasticity, comprising a flavone-based compound or Kaempferia parviflora extract, as an active ingredient. The composition of the present invention has superior effects of inhibiting collagenases and promoting collagen production, and therefore, may be effective in preventing skin wrinkles and aging and improving skin elasticity, and has superior effects of inhibiting loss of skin moisture and thus is effective in skin moisturizing.
摘要翻译：本发明涉及一种黄酮类化合物或小叶草提取物的新用途，更具体地说，涉及一种抗皱，抗衰老，改善皮肤弹性的组合物，其含有黄酮类化合物或小叶草（Kaempferia parviflora extract），作为活性成分。本发明的组合物具有抑制胶原酶和促进胶原蛋白生成的优异效果，因此可以有效地防止皮肤皱纹和老化并改善皮肤弹性，并且具有抑制皮肤水分损失的优异效果，因此在皮肤中有效保湿。

7. 发明申请

WO2009107896A1 COMPOSITIONS CONTAINING KAEMPFERIA PANDURATA EXTRACT FOR PREVENTING OR TREATMENT SKIN DISEASE 审中-公开
标题翻译：含有KAEMPFERIA PANDURATA提取物的组合物，用于预防或治疗皮肤疾病
公开(公告)号：WO2009107896A1
公开(公告)日：2009-09-03
申请号：PCT/KR2008/002006
申请日：2008-04-10
申请人： AMOREPACIFIC CORPORATION , HWANG, Jae Kwan , LEE, Chan Woo , KIM, Han Sung , KWACK, Il Young , SONG, Xian Li , KIM, Jin Wong , KIM, Han Kon , SHIM, Jae Seok
发明人： HWANG, Jae Kwan , LEE, Chan Woo , KIM, Han Sung , KWACK, Il Young , SONG, Xian Li , KIM, Jin Wong , KIM, Han Kon , SHIM, Jae Seok
IPC分类号： A61K8/97
CPC分类号： A61K8/97 , A61K2800/75 , A61Q7/00 , A61Q19/00
摘要： The present invention relates to a composition effective in preventing or treating skin diseases, more particularly to a composition comprising Kaempferia pandurata extract and effective in preventing or treating skin diseases associated with sebum and skin diseases caused by skin irritation or inflammation. The composition comprising the Kaempferia pandurata extract is effective in preventing or treating skin diseases, for example, skin diseases associated with sebum and skin diseases caused by skin irritation or inflammation.
摘要翻译：本发明涉及一种有效预防或治疗皮肤疾病的组合物，更具体地说涉及一种包含山茶提取物的组合物，其有效预防或治疗由皮肤刺激或炎症引起的与皮脂和皮肤疾病有关的皮肤病。包含高山羊皮提取物的组合物可有效预防或治疗皮肤疾病，例如与由皮肤刺激或炎症引起的皮脂和皮肤疾病相关的皮肤疾病。

8. 发明申请

WO2008156345A2 USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT 审中-公开
标题翻译： LIGNAN化合物用于抗皱治疗的用途
公开(公告)号：WO2008156345A2
公开(公告)日：2008-12-24
申请号：PCT/KR2008/003547
申请日：2008-06-20
申请人： BIOCARE CO., LTD. , HWANG, Jae-Kwan , LEE, Hae Ji , LEE, Jae Young , SHIM, Jae-Seok , KIM, Jeong Hwan
发明人： HWANG, Jae-Kwan , LEE, Hae Ji , LEE, Jae Young , SHIM, Jae-Seok , KIM, Jeong Hwan
IPC分类号： A61K8/34
CPC分类号： A61K8/97 , A61K8/347 , A61K8/498 , A61Q19/08
摘要： The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme- 1(MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.
摘要翻译：本发明涉及木糖素化合物的新用途，其从肉豆蔻或肉豆蔻的肠道中分离和纯化用于抗皱，更具体地，本发明涉及用于抗皱的提取物的抗皱纹的新用途肉豆蔻或肉豆蔻，fragrin A，奥维菌素7，licarin E和肉豆蔻衣木脂的提取物。本发明的提取物和木脂素化合物具有抑制胶原降解酶-1（MMP-1，基质金属蛋白酶-1）和新型胶原（1型前胶原）的形成的作用，从而具有抑制由光老化。因此，本发明的提取物和木酚素化合物可用于预防或治疗由光老化引起的皱纹。

9. 发明申请

WO2006135197A1 IMMUNOSTIMULATING POLYSACCHARIDES ISOLATED FROM CURCUMA XANTHORRHIZA AND MANUFACTURING METHOD THEREOF 审中-公开
标题翻译：免疫球蛋白分离多糖和其制备方法
公开(公告)号：WO2006135197A1
公开(公告)日：2006-12-21
申请号：PCT/KR2006/002282
申请日：2006-06-14
申请人： HWANG, Jae-Kwan , KIM, Ah-Jin , SOHN, Jong-Hee , HAN, Kyu-Lee , LEE, Sun-Hee , CHOO, Jeong-Han
发明人： HWANG, Jae-Kwan , KIM, Ah-Jin , SOHN, Jong-Hee , HAN, Kyu-Lee , LEE, Sun-Hee , CHOO, Jeong-Han
IPC分类号： C08B37/00
CPC分类号： C08B37/006 , C12P19/04
摘要： The present invention provides a method for manufacturing polysaccharides isolated from Curcuma xanthorrhiza , including steps of: (S1) preparing a powder of Curcuma xanthorrhiza Roxb .; (S2) extracting the powder with an organic solvent, and then filtering or centrifuging to obtain a residue; (S3) extracting the residue to prepare a solution containing polysaccharides; (S4) removing starch by adding starch-hydrolyzing enzyme to the polysaccharides-containing solution; (S5) precipitating the polysaccharides after the step (S4); and (S6) purifying the polysaccharides after the step (S5), polysaccharides obtained according to the manufacturing method, and a pharmaceutical composition in eluding the polysaccharides as effective component. The polysaccharides according to the present invention may be very effectively used in drugs and functional foods for stimulating macrophage activity, preventing and treating immunological diseases including cancer, and enhancing immunity after the treatment of the immunological diseases.
摘要翻译：本发明提供了从姜黄分离的多糖的制造方法，包括以下步骤：（S1）制备姜黄黄酮粉末; （S2）用有机溶剂萃取粉末，然后过滤或离心得到残留物; （S3）提取残渣以制备含有多糖的溶液; （S4）通过向含多糖溶液中加入淀粉水解酶除去淀粉; （S5）在步骤（S4）后沉淀多糖; 和（S6）步骤（S5）后的多糖的纯化，根据制造方法得到的多糖，以及除了多糖作为有效成分的药物组合物。本发明的多糖可以非常有效地用于药物和功能性食品中，用于刺激巨噬细胞活性，预防和治疗免疫疾病，包括癌症，以及增强免疫疾病治疗后的免疫力。

10. 发明申请

WO2005072691A1 COMPOSITION FOR INHIBITING HALITOSIS 审中-公开
标题翻译：用于抑制麻痹症的组合物
公开(公告)号：WO2005072691A1
公开(公告)日：2005-08-11
申请号：PCT/KR2005/000312
申请日：2005-02-02
申请人： LG HOUSEHOLD & HEALTH CARE LTD. , HWANG, Jae-Kwan , KIM, Hyung-Jin , KIM, Seung-Jin , KIM, Jong-Il , KANG, Taek-Kyun , KANG, Sang-Jin , CHO, Wan-Goo , KIM, Sang-Nyun
发明人： HWANG, Jae-Kwan , KIM, Hyung-Jin , KIM, Seung-Jin , KIM, Jong-Il , KANG, Taek-Kyun , KANG, Sang-Jin , CHO, Wan-Goo , KIM, Sang-Nyun
IPC分类号： A61K7/16
CPC分类号： A61K31/30 , A61K8/19 , A61K8/347 , A61K31/05 , A61K33/34 , A61Q11/00 , A61K2300/00
摘要： Disclosed is a composition for inhibiting halitosis, which includes 0.01. 5 wt% of xanthorrhizol; and 0.0001 - 1 wt% of copper compound on the basis of total weight of the composition. The composition for inhibiting halitosis according to the present invention exhibits strong effects in inhibiting halitosis by effective halitosis-inhibiting system due to synergy between xanthorrhizol and copper compound in the composition.
摘要翻译：公开了用于抑制口臭的组合物，其包括0.01。 5％（重量）的黄嘌呤; 和基于组合物总重量的0.0001-1重量％的铜化合物。根据本发明的用于抑制口臭的组合物由于在组合物中的黄嘌呤和铜化合物之间的协同作用而显示出有效的口臭抑制体系抑制口臭的效果。

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