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1. 发明申请

WO2007146767A3 BACTERIAL GLUTAMINE SYNTHETASES AND METHODS OF USE 审中-公开
标题翻译：细菌谷氨酰胺合成酶及其使用方法
公开(公告)号：WO2007146767A3
公开(公告)日：2008-04-17
申请号：PCT/US2007070690
申请日：2007-06-08
申请人： ATHENIX CORP , DUCK NICHOLAS B , HINSON TODD K , BEILINSON VADIM , SCHOUTEN LAURA COOPER , TOMSO DANIEL JOHN
发明人： DUCK NICHOLAS B , HINSON TODD K , BEILINSON VADIM , SCHOUTEN LAURA COOPER , TOMSO DANIEL JOHN
IPC分类号： A01H5/00 , C12N9/00 , C12N15/52 , C12N15/82
CPC分类号： C12N15/8277 , C12N9/93
摘要： Compositions and methods for conferring herbicide resistance to and improving nitrogen utilization of bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to herbicidal glutamine synthetase inhibitors are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides corresponding to herbicidal glutamine synthetase inhibitor-resistant polynucleotides are provided. Additionally, polypeptides corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides comprising a variant of SEQ ID NO: 1, wherein the variant polynucleotide encodes a polypeptide that is resistant to inhibition by herbicidal glutamine synthetase inhibitor.
摘要翻译：提供了赋予除草剂抵抗和改善细菌，植物，植物细胞，组织和种子的氮利用的组合物和方法。提供了包含赋予除草谷氨酰胺合成酶抑制剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了对应于除草谷氨酰胺合成酶抑制剂抗性多核苷酸的分离的多核苷酸。另外，包括对应于多核苷酸的多肽。特别地，本发明提供了包含SEQ ID NO：1的变体的分离的多核苷酸，其中所述变体多核苷酸编码对除草谷氨酰胺合成酶抑制剂具有抑制作用的多肽。

2. 发明申请

WO2007146767A8 BACTERIAL GLUTAMINE SYNTHETASES AND METHODS OF USE 审中-公开
标题翻译：细菌谷氨酰胺合成酶及其使用方法
公开(公告)号：WO2007146767A8
公开(公告)日：2008-02-14
申请号：PCT/US2007070690
申请日：2007-06-08
申请人： ATHENIX CORP , DUCK NICHOLAS B , HINSON TODD K , BEILINSON VADIM , SCHOUTEN LAURA COOPER , TOMSO DANIEL JOHN
发明人： DUCK NICHOLAS B , HINSON TODD K , BEILINSON VADIM , SCHOUTEN LAURA COOPER , TOMSO DANIEL JOHN
IPC分类号： C12N9/00 , A01H5/00 , C12N15/52 , C12N15/82
CPC分类号： C12N15/8277 , C12N9/93
摘要： Compositions and methods for conferring herbicide resistance to and improving nitrogen utilization of bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to herbicidal glutamine synthetase inhibitors are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides corresponding to herbicidal glutamine synthetase inhibitor-resistant polynucleotides are provided. Additionally, polypeptides corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides comprising a variant of SEQ ID NO: 1, wherein the variant polynucleotide encodes a polypeptide that is resistant to inhibition by herbicidal glutamine synthetase inhibitor.
摘要翻译：提供了赋予除草剂抗性并改善细菌，植物，植物细胞，组织和种子的氮利用的组合物和方法。提供了包含赋予对除草谷氨酰胺合成酶抑制剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可以用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包含转化的细菌，植物，植物细胞，组织和种子。具体而言，提供了对应于除草谷氨酰胺合成酶抑制剂抗性多核苷酸的分离的多核苷酸。另外，包含对应于多核苷酸的多肽。具体而言，本发明提供了包含SEQ ID NO：1的变体的分离的多核苷酸，其中所述变体多核苷酸编码抗除草谷氨酰胺合成酶抑制剂抑制的多肽。

3. 发明申请

WO2006110188A9 GENES CONFERRING HERBICIDE RESISTANCE 审中-公开
标题翻译：基因决定抗药性
公开(公告)号：WO2006110188A9
公开(公告)日：2006-12-07
申请号：PCT/US2005046608
申请日：2005-12-22
申请人： ATHENIX CORP , HAMMER PHILIP E , HINSON TODD K
发明人： HAMMER PHILIP E , HINSON TODD K
IPC分类号： C12N15/82 , A01H5/00 , C12N9/10
CPC分类号： C12N9/1092 , C07K14/195 , C12N15/8275
摘要： Compositions and methods for conferring herbicide resistance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to glyphosate herbicides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated nucleic acid molecules corresponding to glyphosate resistant nucleic acid sequences are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3 or the nucleotide sequence set forth in SEQ ID NO:1 or 2.
摘要翻译：提供了赋予除草剂对细菌，植物，植物细胞，组织和种子的抗性的组合物和方法。提供了包含赋予对草甘膦除草剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了对应于草甘膦抗性核酸序列的分离的核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了包含编码SEQ ID NO：3所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或2所示的核苷酸序列的分离的核酸分子。

4. 发明申请

WO2008100353A2 IMPROVED GRG23 EPSP SYNTHASES: COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译：改进的GRG23 EPSP合成：组合物和使用方法
公开(公告)号：WO2008100353A2
公开(公告)日：2008-08-21
申请号：PCT/US2007085164
申请日：2007-11-20
申请人： ATHENIX CORP , SCHOUTEN LAURA COOPER , PETERS CHERYL , VANDE BERG BRIAN , HINSON TODD
发明人： SCHOUTEN LAURA COOPER , PETERS CHERYL , VANDE BERG BRIAN , HINSON TODD
IPC分类号： C12N15/82
CPC分类号： C12N15/8275 , C12N9/1085 , C12N9/1092
摘要： Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds.. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, or 35, or the nucleotide sequence set forth in SEQ ID NO:6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, or 34.
摘要翻译：提供了赋予除草剂抗性或对细菌，植物，植物细胞，组织和种子的耐受性的组合物和方法。组合物包括编码除草剂抗性或耐受性多肽的多核苷酸，包含那些多核苷酸的载体和包含载体的宿主细胞。本发明的核苷酸序列可用于DNA构建体或表达盒中用于在生物体（包括微生物和植物）中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供编码抗草甘膦或多肽的分离的多核苷酸。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了分离的多核苷酸，其含有编码SEQ ID NO：9,11,13,15,17,19,21,23,25,27,29,31,33，或35，或SEQ ID NO：6,8,10,12,14,16,18,20,22,24,26,28,30,32或34所示的核苷酸序列。

5. 发明申请

WO2007146767A2 BACTERIAL GLUTAMINE SYNTHETASES AND METHODS OF USE 审中-公开
标题翻译：细菌谷氨酰胺合成酶及其使用方法
公开(公告)号：WO2007146767A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/070690
申请日：2007-06-08
申请人： ATHENIX CORPORATION , DUCK, Nicholas, B. , HINSON, Todd, K. , BEILINSON, Vadim , SCHOUTEN, Laura, Cooper , TOMSO, Daniel, John
发明人： DUCK, Nicholas, B. , HINSON, Todd, K. , BEILINSON, Vadim , SCHOUTEN, Laura, Cooper , TOMSO, Daniel, John
IPC分类号： C12N9/00 , C12N15/52 , C12N15/82 , A01H5/00
CPC分类号： C12N15/8277 , C12N9/93
摘要： Compositions and methods for conferring herbicide resistance to and improving nitrogen utilization of bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to herbicidal glutamine synthetase inhibitors are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides corresponding to herbicidal glutamine synthetase inhibitor-resistant polynucleotides are provided. Additionally, polypeptides corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides comprising a variant of SEQ ID NO: 1, wherein the variant polynucleotide encodes a polypeptide that is resistant to inhibition by herbicidal glutamine synthetase inhibitor.
摘要翻译：提供了赋予除草剂对细菌，植物，植物细胞，组织和种子的氮利用的抗性和改善的组合物和方法。提供了包含赋予除草谷氨酰胺合成酶抑制剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了对应于除草谷氨酰胺合成酶抑制剂抗性多核苷酸的分离的多核苷酸。另外，包括对应于多核苷酸的多肽。特别地，本发明提供了包含SEQ ID NO：1的变体的分离的多核苷酸，其中所述变体多核苷酸编码对除草谷氨酰胺合成酶抑制剂具有抑制作用的多肽。

6. 发明申请

WO2004111245A3 GDC-2 GENES CONFERRING HERBICIDE RESISTANCE 审中-公开
标题翻译： GDC-2基因对抗药性的抵抗
公开(公告)号：WO2004111245A3
公开(公告)日：2005-05-06
申请号：PCT/US2004007326
申请日：2004-03-10
申请人： ATHENIX CORP , HAMMER PHILIP E , HINSON TODD K , DUCK NICHOLAS B
发明人： HAMMER PHILIP E , HINSON TODD K , DUCK NICHOLAS B
IPC分类号： C12N9/88 , C12N15/82 , A01H5/00 , A01H5/10 , C12N5/10
CPC分类号： C12N9/88 , C12N15/8275 , C12N15/8278
摘要： Compositions and methods for conferring herbicide resistance to plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to glyphosate herbicides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed plants, plant cells, tissues, and seeds. In particular, isolated nucleic acid molecules corresponding to glyphosate resistant nucleic acid sequences are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3 or the nucleotide sequences set forth in SEQ ID NOS: 1 and 2.
摘要翻译：提供了赋予对植物，植物细胞，组织和种子的除草剂抗性的组合物和方法。提供了包含赋予对草甘膦除草剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包括转化的植物，植物细胞，组织和种子。特别地，提供了对应于草甘膦抗性核酸序列的分离的核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：3所示的氨基酸序列的核苷酸序列或SEQ ID NO：1和2所示的核苷酸序列。

7. 发明申请

WO2004097013A1 GDC-1 GENES CONFERRING HERBICIDE RESISTANCE 审中-公开
标题翻译： GDC-1基因抑制抗药性
公开(公告)号：WO2004097013A1
公开(公告)日：2004-11-11
申请号：PCT/US2004/007180
申请日：2004-03-10
申请人： ATHENIX CORPORATION , HAMMER, Philip, E. , HINSON, Todd, K. , CARR, Brian , DUCK, Nicholas, B.
发明人： HAMMER, Philip, E. , HINSON, Todd, K. , CARR, Brian , DUCK, Nicholas, B.
IPC分类号： C12N9/88
CPC分类号： C12N15/8275 , C12N9/88
摘要： Compositions and methods for conferring herbicide resistance to plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to glyphosate herbicides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed plants, plant cells, tissues, and seeds. In particular, isolated nucleic acid molecules corresponding to glyphosate resistant nucleic acid sequences are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding an amino acid sequence shown in SEQ ID NO:3, 6, 8, 11, 19, or 21, or a nucleotide sequence set forth in SEQ ID NO:1, 2, 4, 5, 7, 9, 10, 18, or 20, as well as variants and fragments thereof.
摘要翻译：提供了赋予对植物，植物细胞，组织和种子的除草剂抗性的组合物和方法。提供了包含赋予对草甘膦除草剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包括转化的植物，植物细胞，组织和种子。特别地，提供了对应于草甘膦抗性核酸序列的分离的核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：3,6,8,11,19或21所示氨基酸序列的核苷酸序列或SEQ ID NO： 1，2，4，5，7，9，10，18或20，以及其变体和片段。

8. 发明申请

WO2007082269B1 EPSP SYNTHASE ENZYME DOMAINS CONFERRING GLYPHOSATE RESISTANCE 审中-公开
标题翻译： EPSP SYNTHASE ENZYME域保留谷氨酸电阻
公开(公告)号：WO2007082269B1
公开(公告)日：2008-05-08
申请号：PCT/US2007060396
申请日：2007-01-11
申请人： ATHENIX CORP , CARR BRIAN , HAMMER PHILIP E , HINSON TODD K , VANDE BERG BRIAN
发明人： CARR BRIAN , HAMMER PHILIP E , HINSON TODD K , VANDE BERG BRIAN
IPC分类号： C12N15/82 , A01H5/10 , C12N9/10 , C12N15/54
CPC分类号： C12N15/8275 , C12N9/1092
摘要： Compositions and methods for conferring tolerance to glyphosate in bacteria, plants, plant cells, tissues and seeds are provided. Compositions include novel EPSP synthase enzymes and nucleic acid molecules encoding such enzymes, vectors comprising those nucleic acid molecules, and host cells comprising the vectors. The novel proteins comprise at least one sequence domain selected from the domains provided herein. These sequence domains can be used to identify EPSP synthases with glyphosate resistance activity.
摘要翻译：提供了在细菌，植物，植物细胞，组织和种子中赋予草甘膦耐受性的组合物和方法。组合物包括新型EPSP合成酶和编码这种酶的核酸分子，包含那些核酸分子的载体和包含载体的宿主细胞。新型蛋白质包含选自本文提供的结构域的至少一个序列结构域。这些序列结构域可用于鉴定具有草甘膦抗性活性的EPSP合成酶。

9. 发明申请

WO2007082269A2 EPSP SYNTHASE ENZYME DOMAINS CONFERRING GLYPHOSATE RESISTANCE 审中-公开
标题翻译： EPSP SYNTHASE ENZYME域保留谷氨酸电阻
公开(公告)号：WO2007082269A2
公开(公告)日：2007-07-19
申请号：PCT/US2007060396
申请日：2007-01-11
申请人： ATHENIX CORP , CARR BRIAN , HAMMER PHILIP E , HINSON TODD K , VANDE BERG BRIAN
发明人： CARR BRIAN , HAMMER PHILIP E , HINSON TODD K , VANDE BERG BRIAN
IPC分类号： C07K14/435
CPC分类号： C12N15/8275 , C12N9/1092
摘要： Compositions and methods for conferring tolerance to glyphosate in bacteria, plants, plant cells, tissues and seeds are provided. Compositions include novel EPSP synthase enzymes and nucleic acid molecules encoding such enzymes, vectors comprising those nucleic acid molecules, and host cells comprising the vectors. The novel proteins comprise at least one sequence domain selected from the domains provided herein. These sequence domains can be used to identify EPSP synthases with glyphosate resistance activity.
摘要翻译：提供了在细菌，植物，植物细胞，组织和种子中赋予草甘膦耐受性的组合物和方法。组合物包括新型EPSP合成酶和编码这种酶的核酸分子，包含那些核酸分子的载体和包含载体的宿主细胞。新型蛋白质包含选自本文提供的结构域的至少一个序列结构域。这些序列结构域可用于鉴定具有草甘膦抗性活性的EPSP合成酶。

10. 发明申请

WO2006110188A3 GENES CONFERRING HERBICIDE RESISTANCE 审中-公开
标题翻译：基因决定抗药性
公开(公告)号：WO2006110188A3
公开(公告)日：2007-03-01
申请号：PCT/US2005046608
申请日：2005-12-22
申请人： ATHENIX CORP , HAMMER PHILIP E , HINSON TODD K
发明人： HAMMER PHILIP E , HINSON TODD K
IPC分类号： C12N15/82 , A01H5/00 , C12N9/10
CPC分类号： C12N9/1092 , C07K14/195 , C12N15/8275
摘要： Compositions and methods for conferring herbicide resistance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to glyphosate herbicides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated nucleic acid molecules corresponding to glyphosate resistant nucleic acid sequences are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3 or the nucleotide sequence set forth in SEQ ID NO:1 or 2.
摘要翻译：提供了赋予除草剂对细菌，植物，植物细胞，组织和种子的抗性的组合物和方法。提供了包含赋予对草甘膦除草剂的抗性或耐受性的多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了对应于草甘膦抗性核酸序列的分离的核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了包含编码SEQ ID NO：3所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或2所示的核苷酸序列的分离的核酸分子。

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