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1. 发明申请

WO2010097479A3 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS 审中-公开
标题翻译： CYCLOHEXYL碳酸酯化合物作为活性抗细胞成分
公开(公告)号：WO2010097479A3
公开(公告)日：2011-04-14
申请号：PCT/EP2010057112
申请日：2010-05-25
申请人： SYMRISE AG , MEYER IMKE , OERTLING HEIKO , HILLEBRAND NADINE , GOEMANN CLAUDIA , BRODHAGE RAHIM
发明人： MEYER IMKE , OERTLING HEIKO , HILLEBRAND NADINE , GOEMANN CLAUDIA , BRODHAGE RAHIM
IPC分类号： A61K8/42 , A61Q19/06
CPC分类号： A61K8/44 , A61K31/00 , A61K31/27 , A61Q19/06
摘要： The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I) wherein A denotes (II), wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR1R2, wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.
摘要翻译：本发明涉及以下给出的某些式（I）环己基氨基甲酸酯化合物的化妆品，皮肤病学或治疗用途，优选作为抗脂肪团活性物质。本发明还涉及包含这样的式（I）化合物的组合物和化妆品，皮肤病学或治疗产品，其优选适用于预防（预防）和化妆品处理（抗击）人体中的脂肪团，相应的方法和新的化合物式（I）其中A表示（II），其中X，Y和Z彼此独立地表示氢，C1-C4-烷基或C2-C4-烯基，其中任选地两个基团X，Y和Z共价键合在这样的双环体系中，基团X，Y和Z中的两个一起优选形成具有1至4个碳原子的基团，优选地具有1至3个碳原子的烃基，B 表示NR 1 R 2，其中R 1表示氢或具有1至14个碳原子的有机基团，R 2表示具有1至14个碳原子的有机基团，并且其中任选地R 1和R 2彼此共价键合，优选为该B为3至8元环。

2. 发明申请

WO2010097479A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS 审中-公开
标题翻译： CYCLOHEXYL碳酸酯化合物作为活性抗细胞成分
公开(公告)号：WO2010097479A2
公开(公告)日：2010-09-02
申请号：PCT/EP2010/057112
申请日：2010-05-25
申请人： SYMRISE GMBH & CO. KG , MEYER, Imke , OERTLING, Heiko , HILLEBRAND, Nadine , GÖMANN, Claudia , BRODHAGE, Rahim
发明人： MEYER, Imke , OERTLING, Heiko , HILLEBRAND, Nadine , GÖMANN, Claudia , BRODHAGE, Rahim
CPC分类号： A61K8/44 , A61K31/00 , A61K31/27 , A61Q19/06
摘要： The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I) wherein A denotes (II), wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR 1 R 2 , wherein R 1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R 2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R 1 and R 2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.
摘要翻译：本发明涉及以下给出的某些式（I）环己基氨基甲酸酯化合物的化妆品，皮肤病学或治疗用途，优选作为抗脂肪团活性物质。本发明还涉及包含这样的式（I）化合物的组合物和化妆品，皮肤病学或治疗产品，其优选适用于预防（预防）和化妆品处理（抗击）人体中的脂肪团，相应的方法和新的化合物式（I）其中A表示（II），其中X，Y和Z彼此独立地表示氢，C1-C4-烷基或C2-C4-烯基，其中任选地两个基团X，Y和Z共价键合在这样的双环体系中，基团X，Y和Z中的两个一起优选形成具有1至4个碳原子的基团，优选地具有1至3个碳原子的烃基，B 表示NR 1 R 2，其中R 1表示氢或具有1至14个碳原子的有机基团，R 2表示具有1至14个碳原子的有机基团，并且其中任选地R 1和R 2彼此共价键合，优选为该B为3至8元环。

3. 发明申请

WO2010089421A2 MENTHYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS 审中-公开
标题翻译：戊烯碳酸酯化合物作为活性抗细胞成分
公开(公告)号：WO2010089421A2
公开(公告)日：2010-08-12
申请号：PCT/EP2010/057117
申请日：2010-05-25
申请人： SYMRISE GMBH & CO. KG , MEYER, Imke , OERTLING, Heiko , HILLEBRAND, Nadine , GÖMANN, Claudia , BRODHAGE, Rahim
发明人： MEYER, Imke , OERTLING, Heiko , HILLEBRAND, Nadine , GÖMANN, Claudia , BRODHAGE, Rahim
CPC分类号： A61K8/42 , A61K8/4973 , A61Q19/06 , C07C271/34 , C07C271/36 , C07C271/38 , C07C2601/14 , C07D307/14 , C07D317/58
摘要： The present invention relates to the cosmetic, dermatological or therapeutic use of certain menthyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and to certain novel compounds of formula (I) wherein R 1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R 2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R 1 and R 2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed.
摘要翻译：本发明涉及以下给出的某些式（I）的薄荷基氨基甲酸酯化合物的化妆品，皮肤病学或治疗用途，优选作为抗脂肪团活性成分。本发明还涉及包含这样的式（I）化合物的组合物和化妆品，皮肤病学或治疗产品，其优选适用于预防（预防）和化妆品处理（抗击）人体中的脂肪团，相应的方法和某些新颖的其中R 1表示氢或具有1至14个碳原子的有机基团的式（I）化合物，R 2表示具有1至14个碳原子的有机基团，并且其中任选地R 1和R 2彼此共价键合，优选使得形成3〜8元环。

4. 发明申请

WO2010089421A3 MENTHYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS 审中-公开
标题翻译：戊烯碳酸酯化合物作为活性抗细胞成分
公开(公告)号：WO2010089421A3
公开(公告)日：2011-04-14
申请号：PCT/EP2010057117
申请日：2010-05-25
申请人： SYMRISE AG , MEYER IMKE , OERTLING HEIKO , HILLEBRAND NADINE , GOEMANN CLAUDIA , BRODHAGE RAHIM
发明人： MEYER IMKE , OERTLING HEIKO , HILLEBRAND NADINE , GOEMANN CLAUDIA , BRODHAGE RAHIM
IPC分类号： A61K8/42 , A61Q19/06
CPC分类号： A61K8/42 , A61K8/4973 , A61Q19/06 , C07C271/34 , C07C271/36 , C07C271/38 , C07C2601/14 , C07D307/14 , C07D317/58
摘要： The present invention relates to the cosmetic, dermatological or therapeutic use of certain menthyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and to certain novel compounds of formula (I) wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed.
摘要翻译：本发明涉及以下给出的某些式（I）的薄荷基氨基甲酸酯化合物的化妆品，皮肤病学或治疗用途，优选作为抗脂肪团活性成分。本发明还涉及包含这样的式（I）化合物的组合物和化妆品，皮肤病学或治疗产品，其优选适用于预防（预防）和化妆品处理（抗击）人体中的脂肪团，相应的方法和某些新颖的其中R 1表示氢或具有1至14个碳原子的有机基团的式（I）化合物，R 2表示具有1至14个碳原子的有机基团，并且其中任选地R 1和R 2彼此共价键合，优选使得形成3〜8元环。

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