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    • 2. 发明申请
    • COLOUR MANAGEMENT FOR BIOLOGICAL SAMPLES
    • 生物样本的颜色管理
    • WO2010046821A1
    • 2010-04-29
    • PCT/IB2009/054557
    • 2009-10-16
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.VAN HERPEN, Maarten, M.J.W.VOSSEN, Dirk, L.J.STALLINGA, SjoerdHENDRIKS, Bernardus, H.W.VAN DIJK, Erik, M.H.P.
    • VAN HERPEN, Maarten, M.J.W.VOSSEN, Dirk, L.J.STALLINGA, SjoerdHENDRIKS, Bernardus, H.W.VAN DIJK, Erik, M.H.P.
    • G01N33/52G01N33/569G01N33/58
    • G06T11/001H04N1/62
    • A method of determining a colour transformation for images of biological material comprises - preparing a first set (100) of biological test objects (101–105) using a first preparation method, the set comprising at least one test object; - preparing a second set (130) of biological test objects (131–135) using a second preparation method, each test object (131) in the second set of test objects corresponding to a counterpart test object (101) in the first set of test objects, the test object and its counterpart being of the same biological type of material; - for each test object (101) in the first set of test objects, determining a colour (111) of the test object, thereby generating a first set (110) of colours (111–115); - for each test object (131) in the second set of test objects, determining a colour (121) of the test object, thereby generating a second set (120) of colours (121–125), - generating a conversion table (140) indicating a mapping between the colours in the first set (110) of colours and the corresponding colours in the second set (120) of colours. The first preparation method and the second preparation method may comprise a first staining method and a second staining method, respectively. In a related aspect, an image file comprises - a digital image of a sample containing biological material, the sample having been prepared by a first method, and - a conversion table (140) indicating a mapping between a set of colours associated with the first method and a set of colours associated with a second method of preparing a sample.
    • 确定生物材料的图像的颜色变换的方法包括:使用第一制备方法制备生物测试对象(101-105)的第一组(100),所述组包括至少一个测试对象; - 使用第二准备方法准备生物测试对象(131-135)的第二组(130),所述第二组测试对象中的每个测试对象(131)对应于所述第一组中的对应测试对象(101) 测试对象,测试对象及其对应物具有相同的生物类型的材料; - 对于第一组测试对象中的每个测试对象(101),确定测试对象的颜色(111),从而生成颜色(111-115)的第一组(110); - 对于第二组测试对象中的每个测试对象(131),确定测试对象的颜色(121),由此产生颜色的第二组(120)(120-125), - 生成转换表(140 )指示第一组颜色(110)中的颜色与第二组(120)颜色中的相应颜色之间的映射。 第一制备方法和第二制备方法可以分别包括第一染色方法和第二染色方法。 在相关方面,图像文件包括 - 包含生物材料的样品的数字图像,已经通过第一种方法制备的样本,以及 - 转换表(140),其指示与第一种相关联的一组颜色之间的映射 方法和与准备样品的第二种方法相关联的一组颜色。