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1. 发明申请

WO2012021895A3 SYSTEMS AND METHODS FOR OPTIMIZING PARAMETERS OF ORTHOPAEDIC PROCEDURES 审中-公开
公开(公告)号：WO2012021895A3
公开(公告)日：2012-02-16
申请号：PCT/US2011/047784
申请日：2011-08-15
申请人： SMITH & NEPHEW, INC. , MC KINNON, Brian, W. , MARINESCU TANASOCA, Ruxandra, Cristiana , WINEBARGER, Randy , BOWERS, William, L. , WIEBE, James, B. , LENZ, Nathaniel, M. , WILKINSON, Zachary, C. , HADDOCK, Sean, M. , LANDON, Ryan, L.
发明人： MC KINNON, Brian, W. , MARINESCU TANASOCA, Ruxandra, Cristiana , WINEBARGER, Randy , BOWERS, William, L. , WIEBE, James, B. , LENZ, Nathaniel, M. , WILKINSON, Zachary, C. , HADDOCK, Sean, M. , LANDON, Ryan, L.
IPC分类号： A61F2/46 , A61B5/107 , G06F17/50 , A61F2/30
摘要： Systems and methods for optimizing parameters of an orthopaedic procedure for a particular patient, including parameters relating to the anatomic and biomechanic fit of an implant or implant system implanted into the patient's joint. These systems and methods may utilize patient-specific information gathered pre-operatively in conjunction with optimization algorithms to determine an optimal implant design and an optimal position and orientation for implantation of the implant into the particular patient's joint.

2. 发明申请

WO2012021895A2 SYSTEMS AND METHODS FOR OPTIMIZING PARAMETERS OF ORTHOPAEDIC PROCEDURES 审中-公开
标题翻译：优化方法参数的系统和方法
公开(公告)号：WO2012021895A2
公开(公告)日：2012-02-16
申请号：PCT/US2011047784
申请日：2011-08-15
申请人： SMITH & NEPHEW INC , MC KINNON BRIAN W , MARINESCU TANASOCA RUXANDRA CRISTIANA , WINEBARGER RANDY , BOWERS WILLIAM L , WIEBE JAMES B , LENZ NATHANIEL M , WILKINSON ZACHARY C , HADDOCK SEAN M , LANDON RYAN L
发明人： MC KINNON BRIAN W , MARINESCU TANASOCA RUXANDRA CRISTIANA , WINEBARGER RANDY , BOWERS WILLIAM L , WIEBE JAMES B , LENZ NATHANIEL M , WILKINSON ZACHARY C , HADDOCK SEAN M , LANDON RYAN L
IPC分类号： A61F2/46 , A61B5/107 , A61F2/30 , G06F17/50
CPC分类号： A61B34/10 , A61B5/107 , A61F2/38 , A61F2/44 , A61F2/46 , A61F2002/30616 , A61F2002/4633 , G06F17/50 , G09B23/28
摘要： Systems and methods for optimizing parameters of an orthopaedic procedure for a particular patient, including parameters relating to the anatomic and biomechanic fit of an implant or implant system implanted into the patient's joint. These systems and methods may utilize patient-specific information gathered pre-operatively in conjunction with optimization algorithms to determine an optimal implant design and an optimal position and orientation for implantation of the implant into the particular patient's joint.
摘要翻译：用于优化特定患者的矫形程序的参数的系统和方法，包括与植入患者关节中的植入物或植入物系统的解剖和生物力学拟合有关的参数。这些系统和方法可以利用与优化算法相结合的术前收集的患者特定信息来确定最佳植入物设计以及将植入物植入特定患者关节中的最佳位置和取向。

3. 发明申请

WO2008036580A3 COMPRESSION MOLDING METHOD FOR MAKING BIOMATERIAL COMPOSITES 审中-公开
标题翻译：用于制备生物材料复合材料的压缩成型方法
公开(公告)号：WO2008036580A3
公开(公告)日：2009-04-30
申请号：PCT/US2007078606
申请日：2007-09-17
申请人： WARSAW ORTHOPEDIC INC , HADDOCK SEAN M , KINNANE KEITH M , GROSS JEFFREY M , LYU SUPING , LOY BRIAN A , HOBOT CHRISTOPHER M , SPARER RANDALL V
发明人： HADDOCK SEAN M , KINNANE KEITH M , GROSS JEFFREY M , LYU SUPING , LOY BRIAN A , HOBOT CHRISTOPHER M , SPARER RANDALL V
IPC分类号： B29C43/00 , A61L27/36 , A61L27/40 , A61L27/46 , A61L27/54 , B29C45/00
CPC分类号： A61L27/3608 , A61L27/18 , A61L27/3683 , A61L27/58 , C08L67/04
摘要： A process for making an implantable material comprising a composite of a biocompatible polymer and a bioactive agent. The composite combines desirable mechanical properties of polymers and the bioactivity of tissue or one or more component of tissue. More particularly, but not exclusively, the invention relates to methods for the manufacture of implantable materials, devices and components via a powder molding process.
摘要翻译：一种用于制造可植入材料的方法，其包括生物相容性聚合物和生物活性剂的复合物。该复合物结合聚合物的所需机械性能和组织的生物活性或组织的一种或多种组分。更具体地但不排他地，本发明涉及通过粉末成型工艺制造可植入材料，装置和部件的方法。

4. 发明申请

WO2008027797A2 HYGROSCOPIC TREATMENT FOR DEGENERATING DISCS 审中-公开
标题翻译：用于退化斑块的水解处理
公开(公告)号：WO2008027797A2
公开(公告)日：2008-03-06
申请号：PCT/US2007/076707
申请日：2007-08-24
申请人： WARSAW ORTHOPEDIC, INC , DRAPEAU, Susan, J. , HADDOCK, Sean, M. , ROY, Josee , MARX, Jeffery, C., MD
发明人： DRAPEAU, Susan, J. , HADDOCK, Sean, M. , ROY, Josee , MARX, Jeffery, C., MD
IPC分类号： A61L27/14 , A61L27/50
CPC分类号： A61L27/50 , A61F2002/30075 , A61F2002/444 , A61F2210/0061 , A61L27/14 , A61L2430/38
摘要： Early treatment for a degenerated disc includes identifying a non-ruptured, dehydrated disc. A hygroscopic agent is then selected. This agent should pull water towards itself and have a hygroscopic compound with a molecular weight of at least 400 Daltons. Additionally, it may be desirable to selected hygroscopic compounds that are anionic or electrically neutral. The hygroscopic agent is then injected into the nucleus pulposus of the disc without any prior removal of the nucleus pulposus material. Because the surrounding disc structure allows for the passive diffusion of water into the nucleus pulposus, the hygroscopic agent will draw water into the nucleus pulposus, thus promoting tissue hydration within the disc. The hygroscopic agent may also include a biological agent and/or an imaging agent.
摘要翻译：退化椎间盘的早期治疗包括鉴定未破裂的脱水椎间盘。然后选择吸湿剂。该试剂应将水拉向自身并具有分子量至少为400道尔顿的吸湿性化合物。另外，可能需要选择阴离子或电中性的吸湿化合物。然后将吸湿剂注射到盘的髓核中，而无需先前去除髓核成分材料。因为周围的圆盘结构允许水被钝化地扩散到髓核中，吸湿剂会将水吸入髓核，从而促进椎间盘内的组织水合作用。吸湿剂还可以包括生物制剂和/或成像剂。

5. 发明申请

WO2007130891A1 RETRACTABLE TROCAR AND CANNULA COMBINATION 审中-公开
标题翻译：可收缩的锁和肛门组合
公开(公告)号：WO2007130891A1
公开(公告)日：2007-11-15
申请号：PCT/US2007/067737
申请日：2007-04-30
申请人： WARSAW ORTHOPEDIC, INC , HADDOCK, Sean M. , JUSTIS, Jeff R. , SIMONTON, T. Andrew
发明人： JUSTIS, Jeff R. , SIMONTON, T. Andrew
IPC分类号： A61B17/34
CPC分类号： A61B17/16 , A61B17/1671 , A61B17/3417 , A61B17/3421 , A61B17/7061 , A61B17/8819 , A61B2017/00261 , A61B2017/0046 , A61B2017/00477
摘要： A surgical instrument for insertion into human tissue comprises an outer sleeve (100); a middle sleeve (200) sized and configured to be inserted into said outer sleeve, at least a portion of said middle sleeve being configured to extend beyond said outer sleeve; a trocar (300) sized and configured to be inserted into said middle sleeve, at least a portion of said trocar being configured to extend beyond said outer sleeve; and a handle (18) having a passage coaxial with the passages of said outer sleeve and said middle sleeve and the axis of said trocar. Said handle is adapted to be removably coupled to said outer sleeve, and includes a release mechanism having a first position for holding said trocar, said middle sleeve, and said outer sleeve in fixed relationship to said handle, a second position for holding said middle sleeve and said outer sleeve in fixed relationship to said handle, and a third position for holding said outer sleeve in fixed relationship to said handle.
摘要翻译：用于插入人体组织的手术器械包括外套筒（100）; 尺寸和构造成插入所述外套筒的中间套筒（200），所述中间套筒的至少一部分构造成延伸超过所述外套筒; 套管针（300）的尺寸和构造被插入到所述中间套筒中，所述套管针的至少一部分构造成延伸超过所述外套筒; 以及手柄（18），其具有与所述外套筒和所述中套筒的通道同轴的通道和所述套管针的轴线。所述手柄适于可拆卸地联接到所述外套筒，并且包括具有第一位置的释放机构，所述第一位置用于将所述套管针，所述中间套筒和所述外套筒固定在所述手柄上，第二位置用于保持所述中间套筒并且所述外套筒与所述手柄固定，并且第三位置用于将所述外套筒固定在所述手柄上。

6. 发明申请

WO2007127655A2 DILATING STYLET AND CANNULA 审中-公开
标题翻译： DILATING STYLET和CANNULA
公开(公告)号：WO2007127655A2
公开(公告)日：2007-11-08
申请号：PCT/US2007066917
申请日：2007-04-19
申请人： WARSAW ORTHOPEDIC INC , SIMONTON THOMAS A , JUSTIS JEFF R , HADDOCK SEAN M , KINNANE KEITH M
发明人： SIMONTON THOMAS A , JUSTIS JEFF R , HADDOCK SEAN M , KINNANE KEITH M
IPC分类号： A61B17/34 , A61B17/16 , A61B19/00
CPC分类号： A61B17/3472 , A61B17/1604 , A61B17/1671 , A61B17/3423 , A61B17/8811 , A61B17/8819 , A61B2017/349 , A61B2090/034 , A61M25/0102 , A61M2210/02
摘要： An instrument set is provided that has a tapered configuration that facilitates the insertion of the instrument set into a patient.
摘要翻译：提供了一种具有锥形结构的仪器组，其有助于将仪器组插入患者体内。

7. 发明申请

WO2005072659A2 SYSTEMS AND TECHNIQUES FOR RESTORING AND MAINTAINING INTERVERTEBRAL ANATOMY 审中-公开
标题翻译：恢复和维持椎间融合术的系统和技术
公开(公告)号：WO2005072659A2
公开(公告)日：2005-08-11
申请号：PCT/US2005/001478
申请日：2005-01-19
申请人： SDGI HOLDINGS, INC. , FOLEY, Kevin, T. , MOORE, Jeffrey, D. , DUNCAN, James, P. , HADDOCK, Sean, M. , SIMONTON, Thomas, A.
发明人： FOLEY, Kevin, T. , MOORE, Jeffrey, D. , DUNCAN, James, P. , HADDOCK, Sean, M. , SIMONTON, Thomas, A.
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61B17/025 , A61B2017/0256 , A61F2/28 , A61F2/30965 , A61F2/442 , A61F2/447 , A61F2/4611 , A61F2/4684 , A61F2002/2817 , A61F2002/2835 , A61F2002/3008 , A61F2002/30092 , A61F2002/30112 , A61F2002/30266 , A61F2002/30354 , A61F2002/30382 , A61F2002/30383 , A61F2002/30616 , A61F2002/30772 , A61F2002/308 , A61F2002/30813 , A61F2002/3082 , A61F2002/30904 , A61F2002/30975 , A61F2002/4475 , A61F2002/4623 , A61F2002/4624 , A61F2002/4627 , A61F2002/4628 , A61F2002/4629 , A61F2002/4635 , A61F2002/4681 , A61F2210/0014 , A61F2220/0025 , A61F2220/0033 , A61F2230/0004 , A61F2230/0082 , A61F2250/0064 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00293 , A61F2310/00329 , A61F2310/00359
摘要： Techniques and systems for distracting a spinal disc space and supporting adjacent vertebrae are provided. Trial instruments are insertable into the disc space to determine a desired disc space height and to select a corresponding implant. Implants can be also be self-distracting and the implant providing the desired disc space height can be implanted in the spinal disc space.
摘要翻译：提供了用于分散脊椎盘空间并支撑相邻椎骨的技术和系统。试验仪器可插入椎间盘空间以确定期望的椎间盘高度并选择相应的植入物。植入物也可以是自分散的，并且提供期望的椎间盘高度的植入物可以植入脊椎盘空间中。

8. 发明申请

WO2011094697A2 VARIABLE OPENING DELIVERY SYSTEM FOR INTERVERTEBRAL DISC THERAPIES 审中-公开
标题翻译：用于椎间盘治疗的可变开放输送系统
公开(公告)号：WO2011094697A2
公开(公告)日：2011-08-04
申请号：PCT/US2011/023194
申请日：2011-01-31
申请人： WARSAW ORTHOPEDIC, INC. , HADDOCK, Sean, M. , DRAPEAU, Susan, J. , SIMONTON, Thomas, A.
发明人： HADDOCK, Sean, M. , DRAPEAU, Susan, J. , SIMONTON, Thomas, A.
IPC分类号： A61B17/34 , A61M5/158 , A61M29/02 , A61B17/70
CPC分类号： A61B1/32 , A61B17/0218 , A61B17/34 , A61B17/3439 , A61B2017/00261 , A61B2017/00473 , A61B2017/0256 , A61M5/158 , A61M2025/0024
摘要： The disclosure is directed to a needle system configured to enlarge an access path in a patient without further cutting into the tissue of the patient so as to reduce recovery time and trauma to the patient. Also provided are methods of using the needle system provided.
摘要翻译：本公开涉及一种针系统，该针系统构造成放大患者中的进入路径而不进一步切入患者的组织中，从而减少患者的恢复时间和创伤。还提供了使用所提供的针系统的方法。

9. 发明申请

WO2010051383A4 A DEVICE AND METHOD FOR DELIVERY OF A DRUG DEPOT 审中-公开
标题翻译：用于递送药物的装置和方法
公开(公告)号：WO2010051383A4
公开(公告)日：2010-10-14
申请号：PCT/US2009062612
申请日：2009-10-29
申请人： WARSAW ORTHOPEDIC INC , SIMONTON THOMAS A , MCKAY WILLIAM F , HADDOCK SEAN M , ZANELLA JOHN MYERS
发明人： SIMONTON THOMAS A , MCKAY WILLIAM F , HADDOCK SEAN M , ZANELLA JOHN MYERS
IPC分类号： A61M5/178 , A61M5/00
CPC分类号： A61M25/00 , A61B5/04001 , A61B5/4893 , A61M25/007 , A61M25/0084
摘要： Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.
摘要翻译：提供药物库递送装置和方法用于将一个或多个药物储存器递送到具有或不具有重新定位插管的患者皮肤下方的一个或多个部位。该装置具有能够插入到患者皮肤下方的部位的插管和用于递送药物库的一个或多个侧口开口。侧端口与钝头间隔开一段距离，这将允许使用者以距离神经一定距离植入。该装置还可以包括用于检测套管尖端与神经的接近的电子监视器。在一些实施方案中，通过检测神经并将药物贮存库输送到神经中或附近来提供递送药物库的方法。

10. 发明申请

WO2010051383A3 A DEVICE AND METHOD FOR DELIVERY OF A DRUG DEPOT 审中-公开
标题翻译：一种用于递送药物库的设备和方法
公开(公告)号：WO2010051383A3
公开(公告)日：2010-08-26
申请号：PCT/US2009062612
申请日：2009-10-29
申请人： WARSAW ORTHOPEDIC INC , SIMONTON THOMAS A , MCKAY WILLIAM F , HADDOCK SEAN M , ZANELLA JOHN MYERS
发明人： SIMONTON THOMAS A , MCKAY WILLIAM F , HADDOCK SEAN M , ZANELLA JOHN MYERS
IPC分类号： A61M5/178 , A61M5/00
CPC分类号： A61M25/00 , A61B5/04001 , A61B5/4893 , A61M25/007 , A61M25/0084
摘要： Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.
摘要翻译：提供药物贮库递送装置和方法，用于在将套管重新定位或不重新定位的情况下将一个或多个药物贮库递送至患者皮肤下方的一个或多个部位。该装置具有能够插入患者皮肤下方部位的套管和用于输送药物仓库的一个或多个侧口开口。侧端口开口与钝头间隔开一定距离，这将允许使用者在离神经设定的距离处植入。该装置还可以包括用于检测套管的尖端与神经的接近程度的电子监视器。在一些实施方案中，通过检测神经并在神经处或神经附近递送药物贮库来提供递送药物长效制剂的方法。

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