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1. 发明申请

WO2009149880A1 LACTOBACILLUS HELVETICUS STRAINS FOR PRODUCING HYPOTENSIVE PEPTIDES 审中-公开
标题翻译： Lactobacillus HELVETICUS菌株用于生产低温肽
公开(公告)号：WO2009149880A1
公开(公告)日：2009-12-17
申请号：PCT/EP2009/004092
申请日：2009-06-08
申请人： NESTEC S.A. , GRIGOROV, Martin , GERMOND, Jacques-Edouard , TOURNADE, Sylvie , AFFOLTER, Michael
发明人： GRIGOROV, Martin , GERMOND, Jacques-Edouard , TOURNADE, Sylvie , AFFOLTER, Michael
IPC分类号： A23C9/123 , A23C9/13 , A23L1/305 , C07K5/08 , A61P9/12
CPC分类号： A23C9/1234 , A23C9/1322 , A23L33/18 , A23Y2220/39 , C07K5/0808
摘要： The present invention relates to novel strains of Lactobacillus helveticus that can produce high amounts of hypotensive peptides, in particular IPP, VPP and LPP. It also relates to a fermented milk product containing a mixture of tripeptides IPP-VPP-LPP and a strain of L. helveticus. The invention further relates to the specific peptide mixture consisting of tripeptides IPP, VPP and LPP and the use of the fermented product or mixture of peptides in food products, food supplement or pharmaceutical compositions for reducing or preventing hypertension.
摘要翻译：本发明涉及可产生大量降血压肽，特别是IPP，VPP和LPP的新型瑞士乳杆菌菌株。它还涉及含有三肽IPP-VPP-LPP和瑞士乳杆菌菌株的混合物的发酵乳制品。本发明还涉及由三肽IPP，VPP和LPP组成的特定肽混合物，以及食品中的发酵产物或肽混合物的用途，用于降低或预防高血压的食品补充剂或药物组合物。

2. 发明申请

WO2006037655A2 BIOACTIVE COMPOSITIONS, NATURAL METHODS OF PRODUCING THEM AND COMPUTATIONAL METHODS FOR DESIGNING NATURAL PRODUCTION PROCESSES 审中-公开
标题翻译：生物组合物，自然生产方法和设计自然生产过程的计算方法
公开(公告)号：WO2006037655A2
公开(公告)日：2006-04-13
申请号：PCT/EP2005010837
申请日：2005-10-07
申请人： NESTEC SA , GRIGOROV MARTIN , VAN BLADEREN PETER , ZACHARIAE ULRICH , KOCHHAR SUNIL , FAY LAURENT-BERNARD , CORTHESY-THEULAZ IRENE , JUILLERAT MARCEL-ALEXANDRE , AFFOLTER MICHAEL
发明人： GRIGOROV MARTIN , VAN BLADEREN PETER , ZACHARIAE ULRICH , KOCHHAR SUNIL , FAY LAURENT-BERNARD , CORTHESY-THEULAZ IRENE , JUILLERAT MARCEL-ALEXANDRE , AFFOLTER MICHAEL
IPC分类号： C12P21/00 , C07K14/575 , C07K14/72
CPC分类号： A61K36/74 , A23L33/18 , A61K36/48 , A61K36/81 , A61K36/899 , A61K38/168 , A61K2300/00
摘要： The present invention is directed to procedures for the controlled natural bioprocessing of naturally occurring biological molecules by processing activities present in select organisms, extracts of such organisms or other natural processing agents. The invention also covers the methods for developing these procedures and compositions prepared by the procedures.
摘要翻译：本发明涉及通过加工选择生物体中存在的活性，这种生物体的提取物或其它天然加工剂来控制天然存在的生物分子的天然生物处理的方法。本发明还包括用于开发这些方法和通过该方法制备的组合物的方法。

3. 发明申请

WO2006037655A3 BIOACTIVE COMPOSITIONS, NATURAL METHODS OF PRODUCING THEM AND COMPUTATIONAL METHODS FOR DESIGNING NATURAL PRODUCTION PROCESSES 审中-公开
公开(公告)号：WO2006037655A3
公开(公告)日：2006-04-13
申请号：PCT/EP2005/010837
申请日：2005-10-07
申请人： NESTEC S.A. , GRIGOROV, Martin , VAN BLADEREN, Peter , ZACHARIAE, Ulrich , KOCHHAR, Sunil , FAY, Laurent-Bernard , CORTHESY-THEULAZ, Irène , JUILLERAT, Marcel-Alexandre , AFFOLTER, Michael
发明人： GRIGOROV, Martin , VAN BLADEREN, Peter , ZACHARIAE, Ulrich , KOCHHAR, Sunil , FAY, Laurent-Bernard , CORTHESY-THEULAZ, Irène , JUILLERAT, Marcel-Alexandre , AFFOLTER, Michael
IPC分类号： C12P21/06 , A23J3/34 , C07K14/575 , C07K14/72
摘要： The present invention is directed to procedures for the controlled natural bioprocessing of naturally occurring biological molecules by processing activities present in select organisms, extracts of such organisms or other natural processing agents. The invention also covers the methods for developing these procedures and compositions prepared by the procedures.

4. 发明申请

WO2004081018A1 PYRIDINIUM-BETAIN COMPOUNDS AND THEIR USE 审中-公开
标题翻译：吡啶鎓化合物及其用途
公开(公告)号：WO2004081018A1
公开(公告)日：2004-09-23
申请号：PCT/EP2003/002594
申请日：2003-03-10
申请人： NESTEC S.A. , BLANK, Imre , GRIGOROV, Martin , HOFMANN, Thomas
发明人： BLANK, Imre , GRIGOROV, Martin , HOFMANN, Thomas
IPC分类号： C07F9/6558
CPC分类号： C07H13/00 , A23L27/2056 , C07F9/65586
摘要： The present invention concerns Pyridinium-Betain compounds of the following general formula (A) R 1 is H; R 2 is a chemical group formed by a sugar pentose or hexose ring, substituted at C5or C6, respectively, with an acid residue taken from the group - photosphoryl, sulfonyl, or carboxyl, and R 2 is connected to the pyridaine ring either at C1 or C2 positions; R 3 is taken from the group consisting of OH, including the ionised form O - , R 4 is an aliphatic chain (CH 2 ) n , where n is the chain length in the range from n=0 to n=4, R 5 is taken from the group consisting of residues - hydroxy, methoxy, ethoxy, methyl, ethyl, furfurylthio and derivatives, and wherein the counter-ion is taken from the group consisting of sodium, potassium, ammonium, calcium, chloride, carbonate, sulphate, phosphate, and the like.
摘要翻译：本发明涉及以下通式（A）的吡啶鎓 - 甜菜碱化合物：R1为H; R2是由分别在C5或C6取代的糖戊糖或己糖环形成的化学基团，其中酸残基取自基团 - 酰基，磺酰基或羧基，R2与C1或C2连接在吡啶环上位置; R3取自OH，包括电离形式O - ，R4是脂族链（CH2）n，其中n是从n = 0到n = 4的范围内的链长，取R5 由羟基，甲氧基，乙氧基，甲基，乙基，糠基硫代和衍生物组成的组中，所述抗衡离子取自钠，钾，铵，钙，氯化物，碳酸盐，硫酸盐，磷酸盐，等等。

5. 发明申请

WO2003088768A1 FLAVOURING COMPOSITIONS CONTAINING N-ACETYLGLYSINE 审中-公开
标题翻译：含有N-乙酰胆碱的挥发性组合物
公开(公告)号：WO2003088768A1
公开(公告)日：2003-10-30
申请号：PCT/EP2003/003662
申请日：2003-04-08
申请人： SOCIETE DES PRODUITS NESTLE S.A. , GRIGOROV, Martin , SCHLICHTHERLE-CERNY, Hedwig , AFFOLTER, Michael , KOCHHAR, Sunil , JUILLERAT, Marcel, Alexandre
发明人： GRIGOROV, Martin , SCHLICHTHERLE-CERNY, Hedwig , AFFOLTER, Michael , KOCHHAR, Sunil , JUILLERAT, Marcel, Alexandre
IPC分类号： A23L1/226
CPC分类号： A23L27/21
摘要： The present invention relates to flavouring compositions and use of such compositions containing N-acetylglycine as taste enhancer in order to impart umami taste to food-stuffs.
摘要翻译：本发明涉及调味组合物以及含有N-乙酰甘氨酸作为增味剂的这种组合物的用途，以便将食味赋予鲜味。

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