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1. 发明申请

WO2012067995A2 OPTOFLUIDIC PHOTOBIOREACTOR APPARATUS, METHOD, AND APPLICATIONS 审中-公开
标题翻译：光流式光生物反应器装置，方法和应用
公开(公告)号：WO2012067995A2
公开(公告)日：2012-05-24
申请号：PCT/US2011/060557
申请日：2011-11-14
申请人： CORNELL UNIVERSITY , ERICKSON, David , SINTON, David
发明人： ERICKSON, David , SINTON, David
IPC分类号： C12M1/42 , C12M3/00 , C12N1/12 , C12P7/00 , C12P5/02 , C10L1/02 , C12R1/89
CPC分类号： C12M31/08 , C10L1/02 , C12M21/02 , C12M31/02 , C12N1/12 , C12N1/20 , C12P7/24
摘要： An optofluidic photobioreactor including an optical waveguide having an input, characterized by an evanescent optical field confined along an outer surface of the optical waveguide produced by radiation propagating in the optical waveguide, means for inputting light to the input of the optical waveguide, and a selected photosynthetic microorganism disposed substantially within the evanescent field. A method for optically exciting a photosynthetic microorganism for generating a biofuel, a biofuel pre-cursor, or a biomass from the optically-excited photosynthetic microorganism involves irradiating the photosynthetic microorganism attached to the surface of the waveguide with an evanescent optical field from optical radiation propagating in the optical waveguide, and driving photosynthesis in the microorganism by the evanescent optical field.
摘要翻译：一种光流控光生物反应器，包括具有输入的光波导，其特征在于沿着光波导的外表面限定的渐逝光场，该渐变光场由在光波导中传播的辐射产生，用于将光输入到输入以及基本上设置在瞬逝场内的选择的光合微生物。用于从光学激励光合微生物中光学激发用于生成生物燃料，生物燃料前体或生物质的光合微生物的方法涉及用来自光辐射传播的渐逝光场照射附着于波导表面的光合微生物在光波导中，并通过瞬逝光场驱动微生物中的光合作用。

2. 发明申请

WO2010045357A2 ENHANCED ON-CHIP SERS BASED BIOMOLECULAR DETECTION USING ELECTROKINETICALLY ACTIVE MICROWELLS 审中-公开
标题翻译：使用电动活性微球增强基于片上SERS的生物分子检测
公开(公告)号：WO2010045357A2
公开(公告)日：2010-04-22
申请号：PCT/US2009/060675
申请日：2009-10-14
申请人： CORNELL UNIVERSITY , ERICKSON, David , HUH, Yun Suk , BATT, Carl A. , LOWE, Adam Joseph
发明人： ERICKSON, David , HUH, Yun Suk , BATT, Carl A. , LOWE, Adam Joseph
IPC分类号： G01N33/483
CPC分类号： C12Q1/6827 , B01F13/0076 , B01L3/50273 , B01L3/502761 , B01L2300/0636 , B01L2300/0654 , B01L2300/0809 , B01L2300/0829 , B01L2300/0887 , B01L2400/0415 , B01L2400/0424 , C12Q1/6862 , C12Q2565/632 , G01N21/658 , C12Q2563/137 , C12Q2531/137
摘要： A method for detecting target nucleic acids such as SNPs is provided. The method comprises performing a ligase detection reaction (LDR), performing surface enhanced Raman scattering (SERS) on the LDR, and analyzing the outcome of the LDR using analysis and/or quantification of the SERS by detecting an emitted Raman signature. The LDR-SERS method can be used for sensitive and specific detection of any nucleic acid sequence of interest. A microfluidic SERS detection device is also provided. The device comprises electrokinetically active microwells for mixing and concentrating analytes and in which analytes can be quantified. The device can be used for performing the LDR-SERS method in optofluidic chip format.
摘要翻译：提供了检测目标核酸如SNP的方法。该方法包括在LDR上进行连接酶检测反应（LDR），进行表面增强拉曼散射（SERS），并通过检测发射的拉曼特征来分析和/或定量SERS来分析LDR的结果。 LDR-SERS方法可用于感兴趣的任何核酸序列的敏感和特异性检测。还提供了微流体SERS检测装置。该装置包括用于混合和浓缩分析物的电动活性微孔，并且其中可分析物被量化。该器件可用于以光流体芯片格式执行LDR-SERS方法。

3. 发明申请

WO2010030939A1 OPTICAL FORCE BASED BIOMOLECULAR ANALYSIS IN SLOT WAVEGUIDES 审中-公开
标题翻译：光波导中基于光的力分析生物分析
公开(公告)号：WO2010030939A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/056731
申请日：2009-09-11
申请人： ERICKSON, David , LIPSON, Michal , YANG, Allen , SCHMIDT, Brad , MOORE, Sean
发明人： ERICKSON, David , LIPSON, Michal , YANG, Allen , SCHMIDT, Brad , MOORE, Sean
IPC分类号： G02B6/26
CPC分类号： G02B6/122 , G02B6/12007 , G02B6/125 , G02B2006/12061 , G02B2006/12147
摘要： An architecture for the handling and transport of nanoscopic matter in lab on a chip devices using optical forces. A slot waveguide is used to focus and harness optical energy to trap and transport nanoscale objects. The slot waveguide is a unique structure that has several advantageous features, such as high optical confinement, and enables nanoparticles to interact fully with a propagating optical mode.
摘要翻译：在实验室中使用光学力量处理和运输纳米镜物质的芯片器件的架构。狭缝波导用于聚焦和利用光能以捕获和传输纳米级物体。狭缝波导是具有几个有利特征的独特结构，例如高光学限制，并且使得纳米颗粒能够与传播的光学模式完全相互作用。

4. 发明申请

WO2009100405A3 METHODS AND SYSTEMS FOR FAST SCAN LOCATION IDENTIFICATION 审中-公开
标题翻译：用于快速扫描位置识别的方法和系统
公开(公告)号：WO2009100405A3
公开(公告)日：2009-10-08
申请号：PCT/US2009033494
申请日：2009-02-06
申请人： ICONTROL INC , ERICKSON DAVID LEE
发明人： ERICKSON DAVID LEE
IPC分类号： G06F9/44 , G06F3/00
CPC分类号： G06F17/30 , G06Q10/025 , G06Q10/087
摘要： An unknown named territory encloses a known physical target location that is specified by a target longitude and a target latitude. An operation is performed to identify a number of rectangular-shaped terrestrial areas that each enclose both the target longitude and the target latitude. Each of the identified rectangular-shaped terrestrial areas respectively encloses a polygonal-shaped named territory. Each polygonal-shaped named territory is defined by a respective circumscribing set of contiguously positioned vectors. An operation is performed to evaluate the circumscribing sets of contiguously positioned vectors of the polygonal-shaped named territories to determine if a given polygonal-shaped named territory includes both the target longitude and the target latitude. When both the target longitude and the target latitude are found to reside within a given polygonal-shaped named territory, the identity of the given polygonal-shaped named territory is conveyed.
摘要翻译：未知的命名区域包围由目标经度和目标纬度指定的已知物理目标位置。执行操作以识别各自围绕目标经度和目标纬度两者的矩形地面区域的数目。所标识的矩形地面区域中的每一个分别包围多边形形状的指定区域。每个多边形形状的命名区域由相应外接的一组连续定位的矢量定义。执行操作以评估多边形形状命名区域的相邻定位向量的外接集合，以确定给定多边形形状的命名区域是否包括目标经度和目标纬度。当目标经度和目标纬度都被发现存在于一个给定的多边形形状的指定区域内时，传达给定的多边形形状的指定区域的身份。

5. 发明申请

WO2009100259A3 METHODS AND SYSTEMS FOR SHORTENED HASH AUTHENTICATION AND IMPLICIT SESSION KEY AGREEMENT 审中-公开
公开(公告)号：WO2009100259A3
公开(公告)日：2009-08-13
申请号：PCT/US2009/033281
申请日：2009-02-05
申请人： ICONTROL, INC. , ERICKSON, David, Lee
发明人： ERICKSON, David, Lee
IPC分类号： H04L9/32 , H04L9/00
摘要： Secure communication between a client and a server is often required in modern telecommunication systems. Communication security involves identifying and authentication of a client to a server. In general networking systems, complex identification and authentication methods may be deployed. However, such complex security methods typically require substantial computing and power resources on both the client side and server side, as well as substantial communication bandwidth to convey identification and authentication credentials, which may be lengthy. In situations where one or both of the client and server systems are limited on computing and/or power resources, or where a limited communication bandwidth exists between the client and server systems, it is desirable to have a strong identification and authentication security capability that does not compromise system or network operability.

6. 发明申请

WO2009029957A1 NANOSCALE OPTOFLUIDIC DEVICES FOR MOLECULAR DETECTION 审中-公开
标题翻译：用于分子检测的纳米光滑液体装置
公开(公告)号：WO2009029957A1
公开(公告)日：2009-03-05
申请号：PCT/US2008/075066
申请日：2008-09-02
申请人： CORNELL UNIVERSITY , ERICKSON, David , MANDAL, Sudeep
发明人： ERICKSON, David , MANDAL, Sudeep
IPC分类号： G01B9/02
CPC分类号： G01N21/7746 , B01L3/5027 , B82Y20/00 , G01N21/774 , G01N21/78 , G01N2021/7776 , G01N2021/7789 , G02B6/12007 , G02B6/1225 , G02B2006/12061 , G02B2006/1213 , G02B2006/12138
摘要： An optofluidic architecture for label free, highly parallel, detection of molecular interactions is based on the use of optically resonant devices whose resonant wavelength is shifted due to a local change in refractive index caused by a positive binding event between a surface bound molecule and its solution phase target. These devices have an extremely low limit of detection and are compatible with aqueous environments. The device combines the sensitivity (limit of detection) of nanosensor technology with the parallelity of the microarray type format.
摘要翻译：用于无标记，高度平行，分子相互作用检测的光流体结构基于使用光学谐振装置，其谐振波长由于表面结合分子与其溶液之间的正结合事件引起的折射率的局部变化而偏移阶段目标。这些装置具有极低的检测限，并且与水性环境兼容。该器件将纳米传感器技术的灵敏度（检测限）与微阵列型格式的并行性相结合。

7. 发明申请

WO2009014548A1 ELECTRONIC REGISTRATION AND TRANSACTION SYSTEM 审中-公开
标题翻译：电子注册和交易系统
公开(公告)号：WO2009014548A1
公开(公告)日：2009-01-29
申请号：PCT/US2007/082304
申请日：2007-10-23
申请人： ERICKSON, David
发明人： ERICKSON, David
IPC分类号： G06F7/00
CPC分类号： G06Q30/0603 , G06Q20/40 , G06Q40/00
摘要： One preferred embodiment provides mobile device based registrations and transactions by providing an aggregator, in the form of a server connected to the internet for collecting and selectively distributing user data. The aggregator may obtain the user data through the mobile network operator, a third party data source (e.g., a credit reporting bureau), or from one-time user input with the aggregator. The user can selectively transmit their user data quickly (e.g., with the selection of a single link) via their mobile device between the aggregator and a third party content provider (e.g., a gambling site, adult content site, banking site, etc.).
摘要翻译：一个优选实施例通过提供以连接到互联网的服务器的形式的聚合器提供基于移动设备的注册和交易来收集和选择性地分发用户数据。聚合器可以通过移动网络运营商，第三方数据源（例如，信用报告局）或从具有聚合器的一次性用户输入获得用户数据。用户可以通过他们的移动设备在聚合器和第三方内容提供商（例如，赌博站点，成人内容站点，银行站点等）之间快速地（例如，通过选择单个链接）来选择性地发送他们的用户数据，。

8. 发明申请

WO2008097700A3 CHEMICAL ANALYZER FOR INDUSTRIAL PROCESS CONTROL 审中-公开
标题翻译：用于工业过程控制的化学分析仪
公开(公告)号：WO2008097700A3
公开(公告)日：2008-11-20
申请号：PCT/US2008051259
申请日：2008-01-17
申请人： CAMBRIUS INC , BROWN GORDON C , BURKA MICHAEL , CRANTON BRIAN , ERICKSON DAVID , GRASSI JAMES , HAMMOND MATTHEW PATRICK , SHAFFER MAXIMILLAN BEN , VILLENEUVE PIERRE
发明人： BROWN GORDON C , BURKA MICHAEL , CRANTON BRIAN , ERICKSON DAVID , GRASSI JAMES , HAMMOND MATTHEW PATRICK , SHAFFER MAXIMILLAN BEN , VILLENEUVE PIERRE
IPC分类号： G01N21/65 , G01J3/44
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0208 , G01J3/0262 , G01J3/0286 , G01J3/0291 , G01J3/10 , G01J3/26 , G01J3/36 , G01J3/44 , G01J2003/1269 , G01N2021/1793 , G01N2021/8416 , G01N2201/0245 , G01N2201/067
摘要： An optical apparatus for measurement of industrial chemical processes. The analyzer uses Raman scattering and performs measurement of chemical concentrations in continuous or batch processes. The analyzer operates at a standoff distance from the analyte (or analytes) and can measure concentrations through an optical port, facilitating continuous, non-destructive, and non-invasive analysis without extracting the analyte or analytes from the process. The analyzer can measure one or several solid, liquid, or gaseous analytes, or a mixture thereof.
摘要翻译：用于测量工业化学过程的光学设备。该分析仪使用拉曼散射并在连续或间歇过程中执行化学浓度的测量。分析仪与分析物（或多个分析物）隔开一定的距离运行，并可通过光学端口测量浓度，促进连续，非破坏性和非侵入性分析，无需从过程中提取分析物或分析物。分析仪可以测量一种或几种固体，液体或气体分析物或其混合物。

9. 发明申请

WO2008130848A1 METHODS AND APPARATUS FOR TREATMENT OF ANEURYSMS ADJACENT TO BRANCH ARTERIES 审中-公开
标题翻译：用于治疗与分支机构相关的神经元的方法和装置
公开(公告)号：WO2008130848A1
公开(公告)日：2008-10-30
申请号：PCT/US2008/059780
申请日：2008-04-09
申请人： MEDTRONIC VASCULAR INC. , CHU, Jack , ERICKSON, David R. , MORRIS, Jonathan , GANESAN, Prema , HANSON, Curtis , RUST, Matthew , THOMAS, Charles , MACHEK, James
发明人： CHU, Jack , ERICKSON, David R. , MORRIS, Jonathan , GANESAN, Prema , HANSON, Curtis , RUST, Matthew , THOMAS, Charles , MACHEK, James
IPC分类号： A61F2/06
CPC分类号： A61F2/962 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2/954 , A61F2002/061 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/9511 , A61F2220/005 , A61F2220/0075
摘要： A stent graft includes at least one aperture extending through the main body thereof, into which an extension portion may be deployed for positioning within an adjacent branch flow lumen. The extension portions include self biasing features, wherein the extension is biased into engagement with the main body to seal the interface thereof. Additionally, the extension portion may be configured for tortuous or deviated anatomy, to enable sealing of the extension portion with the body while extending the extension portion in a substantially non-radial direction from the main body.
摘要翻译：支架移植物包括延伸穿过其主体的至少一个孔，延伸部分可以布置在其中以便在相邻的分支流动腔内定位。延伸部分包括自偏压特征，其中延伸部被偏置成与主体接合以密封其接口。另外，延伸部分可以被构造成用于曲折或偏离解剖结构，以使得延伸部分能够与本体密封，同时使延伸部分在基本上非径向方向上从主体延伸。

10. 发明申请

WO2007127845A3 RADIOLUCENT BONE PLATE SYSTEMS AND METHODS OF USE 审中-公开
标题翻译：放射性骨板系统及其使用方法
公开(公告)号：WO2007127845A3
公开(公告)日：2008-03-20
申请号：PCT/US2007067500
申请日：2007-04-26
申请人： WARSAW ORTHOPEDIC INC , COMPANIONI WILDER , ERICKSON DAVID R , OI NELSON
发明人： COMPANIONI WILDER , ERICKSON DAVID R , OI NELSON
IPC分类号： A61B17/80
CPC分类号： A61B17/7059 , A61B17/8042 , A61B17/866 , A61B17/8685 , A61B90/39 , A61B2017/00004 , A61B2017/00911
摘要： Apparatus, systems and methods for making, using, implanting, and visualizing portions of a medical implant are provided. One such implant includes a bone plate (30) comprising a radiolucent material having at least one aperture. The implant includes a fastener (32) comprising a radiolucent material adapted to extend through the aperture. The fastener has a distal end and a proximal end, with at least a portion of the proximal end comprising a radiopaque material. A fastener lock (34) is included, adapted to engage the fastener proximal end to maintain the fastener position relative to the bone plate. At least a portion of the fastener lock comprises a radiopaque material. In this manner, at least a portion of the implant is adapted to be visible on a radiographic image.
摘要翻译：提供了用于制造，使用，植入和可视化医疗植入物的部分的装置，系统和方法。一种这样的植入物包括骨板（30），其包括具有至少一个孔的射线可透过材料。植入物包括紧固件（32），其包括适于延伸穿过孔的射线可透过材料。紧固件具有远端和近端，近端的至少一部分包括不透射线材料。包括紧固件锁（34），其适于接合紧固件近端以相对于骨板保持紧固件的位置。紧固件锁的至少一部分包括不透射线的材料。以这种方式，植入物的至少一部分适于在放射照相图像上可见。

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