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1. 发明申请

WO2011008504A2 COMPOSITIONS AND METHODS FOR PRODUCING HYDROCARBONS 审中-公开
标题翻译：用于生产烃类的组合物和方法
公开(公告)号：WO2011008504A2
公开(公告)日：2011-01-20
申请号：PCT/US2010/040257
申请日：2010-06-28
申请人： AMBROZEA, INC. , DAVID, Peter, R.
发明人： DAVID, Peter, R.
IPC分类号： C12P5/00 , C12P7/10 , C12P7/64
CPC分类号： C12P7/08 , C07C1/24 , C07C41/09 , C07C2529/06 , C07C2529/40 , C10G3/49 , C10G2300/1014 , C10G2400/02 , C10G2400/04 , C10G2400/08 , C10L1/02 , C10L1/08 , Y02E50/13 , Y02E50/16 , Y02T50/678 , C07C11/04 , C07C43/06
摘要： The invention involves the conversion of ethanol to a hydrocarbon suitable for use as a fuel. In some embodiments, the ethanol is purified and converted to diethyl ether, which is then converted into a hydrocarbon suitable for use as a fuel.
摘要翻译：本发明涉及将乙醇转化为适合用作燃料的烃。在一些实施方案中，将乙醇纯化并转化为二乙醚，然后将其转化为适合用作燃料的烃。

2. 发明申请

WO2007121100A2 COMPOSITIONS AND METHODS FOR PRODUCING FERMENTATION PRODUCTS AND RESIDUALS 审中-公开
标题翻译：用于生产发酵产品和残留物的组合物和方法
公开(公告)号：WO2007121100A2
公开(公告)日：2007-10-25
申请号：PCT/US2007/066024
申请日：2007-04-05
申请人： AMBROZEA, INC. , DAVID, Peter, R.
发明人： DAVID, Peter, R.
IPC分类号： A61K35/74 , C12P21/06 , C12N1/20
CPC分类号： C12P13/04 , C12N1/18 , C12N1/20 , C12P21/06 , G06Q99/00 , Y02E50/17
摘要： The present invention provides compositions and methods designed to increase value output of a fermentation reaction that yields a first product, intended for commercialization, such as ethanol, and a fermentation residual used, for example, as animal feed. The methods involve using microorganisms in the fermentation process that have been modified so as to yield a residual having greater value that a residual produced in the process by a microorganism not so modified. In particular, the present invention contemplates using microorganisms in a fermentation process that have been modified to increase production of a nutrient, such as an essential amino acid, thereby reducing the need to supplement the nutrient in the animal's diet. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microorganism.
摘要翻译：本发明提供组合物和方法，其设计用于增加产生用于商业化的第一产物（例如乙醇）的发酵反应的价值产物，以及例如用作动物饲料的发酵残余物。所述方法涉及在发酵过程中使用微生物进行修饰，从而产生具有较大值的残留物，即微生物在该过程中产生的残留物未被修饰。特别地，本发明考虑在发酵过程中使用微生物，所述发酵过程已被修饰以增加营养素如必需氨基酸的产量，从而减少补充动物饮食中营养物质的需要。本发明还提供了具有较高商业价值的改性发酵残渣。本发明还提供了完整的动物饲料，包含受试者发酵残留物的营养补充剂。本发明还提供一种进行发酵的方法，改良的发酵微生物和用于修饰这种微生物的遗传载体。

3. 发明申请

WO2002091287A3 DETERMINING STRUCTURES BY PERFORMING COMPARISONS BETWEEN MOLECULAR REPLACEMENT RESULTS FOR MULTIPLE DIFFERENT BIOMOLECULES 审中-公开
公开(公告)号：WO2002091287A3
公开(公告)日：2002-11-14
申请号：PCT/US2002/013988
申请日：2002-05-03
申请人： SYRRX, INC. , MCREE, Duncan , DAVID, Peter, R. , VON DELFT, Frank , RAMMELKAMP, John , ABOLA, Enrique
发明人： MCREE, Duncan , DAVID, Peter, R. , VON DELFT, Frank , RAMMELKAMP, John , ABOLA, Enrique
IPC分类号： G06K9/00
摘要： A method is provided for identifying a search model to use in molecular replacement for determining a structure of a target biomolecule where a group of different biomolecule, such as a protein, From X-ray diffraction data, the method comprising: employing computer executable logic to perform multiple molecular replacement searches on X-ray diffraction data of the target biomolecule where a group of different biomolecule structures are used as search models for the multiple molecular replacement searches; and employing computer executable logic to compare solutions from the multiple molecular replacement searches, the comparison producing data from which biomolecule structures can be identified as having superior structural identity with the target biomolecule as compared to the other biomolecule structures in the group.

4. 发明申请

WO2011008504A3 COMPOSITIONS AND METHODS FOR PRODUCING HYDROCARBONS 审中-公开
标题翻译：用于生产烃的组合物和方法
公开(公告)号：WO2011008504A3
公开(公告)日：2011-05-26
申请号：PCT/US2010040257
申请日：2010-06-28
申请人： AMBROZEA INC , DAVID PETER R
发明人： DAVID PETER R
IPC分类号： C12P5/00 , C12P7/10 , C12P7/64
CPC分类号： C12P7/08 , C07C1/24 , C07C41/09 , C07C2529/06 , C07C2529/40 , C10G3/49 , C10G2300/1014 , C10G2400/02 , C10G2400/04 , C10G2400/08 , C10L1/02 , C10L1/08 , Y02E50/13 , Y02E50/16 , Y02T50/678 , C07C11/04 , C07C43/06
摘要： The invention involves the conversion of ethanol to a hydrocarbon suitable for use as a fuel. In some embodiments, the ethanol is purified and converted to diethyl ether, which is then converted into a hydrocarbon suitable for use as a fuel.
摘要翻译：本发明涉及将乙醇转化为适合用作燃料的烃。在一些实施方案中，乙醇被纯化并转化为乙醚，然后乙醚转化为适合用作燃料的烃。

5. 发明申请

WO2007121100A3 COMPOSITIONS AND METHODS FOR PRODUCING FERMENTATION PRODUCTS AND RESIDUALS 审中-公开
标题翻译：用于生产发酵产品和残留物的组合物和方法
公开(公告)号：WO2007121100A3
公开(公告)日：2008-06-19
申请号：PCT/US2007066024
申请日：2007-04-05
申请人： AMBROZEA INC , DAVID PETER R
发明人： DAVID PETER R
IPC分类号： A61K35/74 , A23K10/38 , C12N1/20 , C12P21/06
CPC分类号： C12P13/04 , C12N1/18 , C12N1/20 , C12P21/06 , G06Q99/00 , Y02E50/17
摘要： The present invention provides compositions and methods designed to increase value output of a fermentation reaction that yields a first product, intended for commercialization, such as ethanol, and a fermentation residual used, for example, as animal feed. The methods involve using microorganisms in the fermentation process that have been modified so as to yield a residual having greater value that a residual produced in the process by a microorganism not so modified. In particular, the present invention contemplates using microorganisms in a fermentation process that have been modified to increase production of a nutrient, such as an essential amino acid, thereby reducing the need to supplement the nutrient in the animal's diet. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microorganism.
摘要翻译：本发明提供组合物和方法，其设计用于增加产生用于商业化的第一产物（例如乙醇）的发酵反应的价值产物，以及例如用作动物饲料的发酵残余物。所述方法涉及在发酵过程中使用微生物进行修饰，从而得到具有较大值的残留物，即微生物在该过程中产生的残留物未被修饰。特别地，本发明考虑在发酵过程中使用微生物，所述发酵过程已被修饰以增加营养素如必需氨基酸的产量，从而减少补充动物饮食中营养物质的需要。本发明还提供了具有较高商业价值的改性发酵残渣。本发明还提供了完整的动物饲料，包含受试者发酵残留物的营养补充剂。本发明还提供一种进行发酵的方法，改良的发酵微生物和用于修饰这种微生物的遗传载体。

6. 发明申请

WO2002101127A1 IN SITU CRYSTAL GROWTH AND ANALYSIS 审中-公开
标题翻译：在现代水晶生长和分析
公开(公告)号：WO2002101127A1
公开(公告)日：2002-12-19
申请号：PCT/US2002/018210
申请日：2002-06-05
申请人： SYRRX, INC. , DAVID, Peter, R. , DAVID, Nathaniel, E.
发明人： DAVID, Peter, R. , DAVID, Nathaniel, E.
IPC分类号： C30B29/58
CPC分类号： G01N25/147 , B01J2219/00274 , C30B7/00 , C30B29/58
摘要： Methods and devices are provided for performing crystallization experiments and analyzing the results of the crystallization experiments in microfluidic devices including a method that comprises: taking a plurality of different crystallization samples in an enclosed microvolume, the plurality of crystallization samples comprising a material to be crystallized and crystallization conditions which vary among the plurality of crystallization samples; allowing crystals of the material to form in the plurality of crystallization sample; and identifying which of the plurality of crystallization samples comprise a precipitate or a crystal of the material.
摘要翻译：提供了用于进行结晶实验和分析微流体装置中的结晶实验的结果的方法和装置，包括包括：在封闭微量体积中取多个不同的结晶样品的方法，所述多个结晶样品包括待结晶的材料，在多个结晶样品中变化的结晶条件; 允许在多个结晶样品中形成材料的晶体; 并且识别多个结晶样品中的哪一个包含材料的沉淀物或晶体。

7. 发明申请

WO2002091287A2 DETERMINING STRUCTURES BY PERFORMING COMPARISONS BETWEEN MOLECULAR REPLACEMENT RESULTS FOR MULTIPLE DIFFERENT BIOMOLECULES 审中-公开
标题翻译：通过在多种不同生物分子的分子结构替代结果之间进行比较来确定结构
公开(公告)号：WO2002091287A2
公开(公告)日：2002-11-14
申请号：PCT/US2002/013988
申请日：2002-05-03
申请人： SYRRX, INC. , MCREE, Duncan , DAVID, Peter, R. , VON DELFT, Frank , RAMMELKAMP, John , ABOLA, Enrique
发明人： MCREE, Duncan , DAVID, Peter, R. , VON DELFT, Frank , RAMMELKAMP, John , ABOLA, Enrique
IPC分类号： G06K9/00
CPC分类号： G06F19/16
摘要： A method is provided for identifying a search model to use in molecular replacement for determining a structure of a target biomolecule where a group of different biomolecule, such as a protein, From X-ray diffraction data, the method comprising: employing computer executable logic to perform multiple molecular replacement searches on X-ray diffraction data of the target biomolecule where a group of different biomolecule structures are used as search models for the multiple molecular replacement searches; and employing computer executable logic to compare solutions from the multiple molecular replacement searches, the comparison producing data from which biomolecule structures can be identified as having superior structural identity with the target biomolecule as compared to the other biomolecule structures in the group.
摘要翻译：提供了一种用于鉴定用于分子替代的用于确定靶生物分子的结构的搜索模型的方法，其中一组不同的生物分子，例如蛋白质，从X射线衍射数据，所述方法包括：使用计算机可执行逻辑对目标生物分子的X射线衍射数据进行多个分子替代搜索，其中使用一组不同的生物分子结构作为多分子替代搜索的搜索模型; 并且使用计算机可执行逻辑来比较来自多个分子替代搜索的解决方案，比较产生生物分子结构与生物分子组织中的其它生物分子结构相比可以被鉴定为具有与靶生物分子具有优异结构同一性的数据。

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