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1. 发明申请

WO2012163413A1 CATHETER FOR DIRECTING BILIOPANCREATIC SECRETIONS 审中-公开
标题翻译：导管双歧杆菌分泌物导管
公开(公告)号：WO2012163413A1
公开(公告)日：2012-12-06
申请号：PCT/EP2011/058981
申请日：2011-05-31
申请人： ETHICON ENDO-SURGERY, INC. , D'ARCANGELO, Michele , ORTIZ, Mark Steven , PASTORELLI, Alessandro , DALESSANDRO, David A. , CONTILIANO, Joseph Henry , DAVE, Vipul Bhupendra
发明人： D'ARCANGELO, Michele , ORTIZ, Mark Steven , PASTORELLI, Alessandro , DALESSANDRO, David A. , CONTILIANO, Joseph Henry , DAVE, Vipul Bhupendra
IPC分类号： A61M25/00 , A61F2/04 , A61F5/00 , A61M27/00
CPC分类号： A61F5/0076 , A61F5/0013 , A61F2002/045 , A61L29/085 , A61L29/148 , A61L2420/04 , A61L2420/08 , A61M25/0045 , A61M27/002 , A61M2025/0019 , C08L67/04
摘要： A catheter (11) for directing biliopancreatic secretions comprises an elongate tubular wall (16) extending between a proximal end portion (12) and a distal end portion (13), the tubular wall (16) having an outer layer (17) and at least one inner coating (18) forming an internal surface (19) which defines a fluid passage channel (20) of the catheter (11), wherein the inner coating (18) is degradable and adapted to detach from the tubular wall (16) together with possible depositions thereon.
摘要翻译：用于引导胰腺分泌物的导管（11）包括在近端部分（12）和远端部分（13）之间延伸的细长管状壁（16），所述管状壁（16）具有外层（17）至少一个内部涂层（18），其形成限定所述导管（11）的流体通道（20）的内表面（19），其中所述内部涂层（18）是可降解的且适于从所述管状壁（16）脱离，以及可能的沉积。

2. 发明申请

WO2009059055A2 METHOD OF MAKING A VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：制造血管闭合装置的方法
公开(公告)号：WO2009059055A2
公开(公告)日：2009-05-07
申请号：PCT/US2008/081867
申请日：2008-10-30
申请人： CORDIS CORPORATION , DAVE, Vipul Bhupendra , SCALZO, Howard , FISHER, Jerry
发明人： DAVE, Vipul Bhupendra , SCALZO, Howard , FISHER, Jerry
IPC分类号： A61L31/04 , A61L31/14 , A61L31/16 , D01F8/04 , D04H3/00
CPC分类号： A61F2/02 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00004 , A61L31/041 , A61L31/141 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/43 , A61L2430/36 , D01D5/34 , D01F1/10 , D01F1/103 , D04H1/42 , Y10T442/2525 , Y10T442/3146 , Y10T442/3154 , Y10T442/3163 , Y10T442/3171 , Y10T442/637 , Y10T442/638 , Y10T442/64 , Y10T442/641 , Y10T442/642 , C08L75/04 , C08L67/04
摘要： A method of making a biocompatible, implantable medical device, including a vascular closure device is disclosed. The method includes forming a biocompatible polymer into at least one fiber and randomly orienting the at least one fiber into a fibrous structure having at least one interstitial spaces. Polymeric materials may be utilized to fabricate any of these devices. The polymeric materials may include additives such as drugs or other bioactive agents as well as antibacterial agents. In such instances, at least one agent, in therapeutic dosage, is incorporated into at least one of the fibrous structure and the at least one fiber.
摘要翻译：公开了制造生物相容性可植入医疗装置的方法，包括血管闭合装置。该方法包括将生物相容性聚合物形成至少一种纤维，并将至少一种纤维随机定向成具有至少一个间隙的纤维结构。可以使用聚合材料来制造任何这些装置。聚合物材料可以包括添加剂如药物或其他生物活性剂以及抗菌剂。在这种情况下，将治疗剂量中的至少一种试剂并入纤维结构和至少一种纤维中的至少一种。

3. 发明申请

WO2009058990A2 VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：血管闭合装置
公开(公告)号：WO2009058990A2
公开(公告)日：2009-05-07
申请号：PCT/US2008/081770
申请日：2008-10-30
申请人： CORDIS CORPORATION , DAVE, Vipul Bhupendra , CHIN-CHEN, Chao
发明人： DAVE, Vipul Bhupendra , CHIN-CHEN, Chao
IPC分类号： A61L31/04 , A61L31/16 , A61L31/14 , D01F8/04 , D04H3/00
CPC分类号： A61F2/02 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00004 , A61L31/041 , A61L31/141 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/43 , A61L2430/36 , D01D5/34 , D01F1/10 , D01F1/103 , D04H1/42 , Y10T442/2525 , Y10T442/3146 , Y10T442/3154 , Y10T442/3163 , Y10T442/3171 , Y10T442/637 , Y10T442/638 , Y10T442/64 , Y10T442/641 , Y10T442/642 , C08L75/04 , C08L67/04
摘要： A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.
摘要翻译：生物相容性材料可以被配置成任何数量的可植入医疗装置，包括血管闭合装置。血管闭合装置包括由至少一个随机取向的纤维形成的纤维结构，所述随机取向的纤维包含至少一种聚合物，以及至少一种治疗剂量的药剂，其结合到至少一种纤维结构中，并且至少一个随机取向的纤维。

4. 发明申请

WO2007134222A3 BALOON EXPANDABLE BIOABSORBABLE DRUG ELUTING STENT 审中-公开
标题翻译： BALOON可扩展的生物可溶性药物涂抹器
公开(公告)号：WO2007134222A3
公开(公告)日：2008-03-06
申请号：PCT/US2007068754
申请日：2007-05-11
申请人： CORDIS CORP , BURGERMEISTER ROBERT , DAVE VIPUL BHUPENDRA , OVERAKER DAVID , MARREY RAMESH
发明人： BURGERMEISTER ROBERT , DAVE VIPUL BHUPENDRA , OVERAKER DAVID , MARREY RAMESH
IPC分类号： A61F2/90
CPC分类号： A61F2/915 , A61F2/82 , A61F2002/825 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2210/0004 , A61F2220/0008 , A61F2220/0075 , A61F2230/0013 , A61F2250/0018 , A61F2250/0028 , A61F2250/0029 , A61F2250/0036 , A61F2250/0062 , A61F2250/0067 , A61F2250/0098 , A61L31/04 , A61L31/16 , A61L31/18 , A61L2300/416
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stent (1000) has a plurality of hoop components (1002) interconnected by a plurality of flexible connectors (1004). The hoop components are formed as a continuous series of substantially longitudinally or axially oriented radial strut members (1006) and alternating substantially circumferentially oriented radial arc members (1008). The geometry of the struts and arcs is such that when the stent is expanded, it has very high strains within a relatively small region (1020). This strain localization results in what is often referred to as "hinging", where the hinge is the small region within which the strains are very high.
摘要翻译：生物相容性材料可以被配置成任何数量的可植入医疗装置，包括腔内支架。聚合材料可用于制造包括支架在内的任何这些装置。支架（1000）具有通过多个柔性连接器（1004）互连的多个环部件（1002）。环形部件形成为基本纵向或轴向定向的径向支柱构件（1006）和交替的基本上周向定向的径向弧形构件（1008）的连续系列。支柱和弧的几何形状使得当支架膨胀时，其在相对小的区域（1020）内具有非常高的应变。这种应变定位导致通常被称为“铰接”，其中铰链是应变非常高的小区域。

5. 发明申请

WO2007070765A3 SELF-EXPANDING STENT DELIVERY SYSTEM 审中-公开
标题翻译：自扩展支架输送系统
公开(公告)号：WO2007070765A3
公开(公告)日：2007-10-25
申请号：PCT/US2006061758
申请日：2006-12-07
申请人： CORDIS CORP , DAVE VIPUL BHUPENDRA , SANCHEZ DIANA MARGARITA
发明人： DAVE VIPUL BHUPENDRA , SANCHEZ DIANA MARGARITA
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/9665
摘要： Self-expanding stent delivery systems and methods having an introducer that receives a delivery catheter. The delivery catheter includes an outer body, an inner body and a stent loaded onto a stent bed within the inner body. At least one anchoring mechanism provided on the inner body helps maintain the undeployed loaded stent appropriately in the stent bed during deployment. The at least one anchoring mechanism can include radiopaque material to increase fluoroscopic visualization of the stent during deployment, and the self-expanding stent can be a bio-absorbable material including drugs or other bio-active agents incorporated therein or provided thereon. After deployment of the stent at the intended treatment site, removal of the inner body and outer body of the delivery catheter and of the introducer occurs.
摘要翻译：自膨式支架输送系统和方法，具有接收输送导管的导引器。输送导管包括外主体，内主体和装载在内主体内的支架床上的支架。设置在内部主体上的至少一个锚固机构有助于在展开期间将未展开的加载支架适当地保持在支架床中。所述至少一个锚定机构可以包括不透射线材料以增加展开期间支架的荧光镜观察，并且自膨胀支架可以是生物可吸收材料，包括掺入其中或提供在其中的药物或其他生物活性剂。在目标治疗部位展开支架后，发生输送导管和导引器的内部主体和外部主体的移除。

6. 发明申请

WO2009058990A3 VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：血管闭合装置
公开(公告)号：WO2009058990A3
公开(公告)日：2010-04-15
申请号：PCT/US2008081770
申请日：2008-10-30
申请人： CORDIS CORP , DAVE VIPUL BHUPENDRA , CHIN-CHEN CHAO
发明人： DAVE VIPUL BHUPENDRA , CHIN-CHEN CHAO
IPC分类号： A61L31/04 , A61L31/14 , A61L31/16 , D01F8/04 , D04H3/00
CPC分类号： A61F2/02 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00004 , A61L31/041 , A61L31/141 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/43 , A61L2430/36 , D01D5/34 , D01F1/10 , D01F1/103 , D04H1/42 , Y10T442/2525 , Y10T442/3146 , Y10T442/3154 , Y10T442/3163 , Y10T442/3171 , Y10T442/637 , Y10T442/638 , Y10T442/64 , Y10T442/641 , Y10T442/642 , C08L75/04 , C08L67/04
摘要： A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.
摘要翻译：生物相容性材料可以被配置成任何数量的可植入医疗装置，包括血管闭合装置。血管闭合装置包括由至少一个随机取向的纤维形成的纤维结构，所述随机取向的纤维包含至少一种聚合物，以及至少一种治疗剂量的药剂，其结合到至少一种纤维结构中，并且至少一个随机取向的纤维。

7. 发明申请

WO2007081621A3 LASER CUT INTRALUMINAL MEDICAL DEVICES 审中-公开
标题翻译：激光切割内科医疗器械
公开(公告)号：WO2007081621A3
公开(公告)日：2008-01-31
申请号：PCT/US2006061668
申请日：2006-12-06
申请人： CORDIS CORP , DAVE VIPUL BHUPENDRA
发明人： DAVE VIPUL BHUPENDRA
IPC分类号： B23K26/36 , B23K26/08
CPC分类号： B23K26/0823 , B23K26/064 , B23K26/0648 , B23K26/066 , B23K26/08 , B23K26/123 , B23K2201/04 , B23K2203/42 , B23K2203/50
摘要： Laser cut bioabsorbable intraluminal devices or stents and methods for forming such an intraluminal device or stent. A precursor sheet (100) or tube (200) of bioabsorbable material is laser cut in the presence of an inert gas to form an intraluminal medical device or stent having a desired geometry or pattern. The device or stent may comprise a helical, or other shape, having the laser cut geometry or pattern imparted thereon. The device or stent may further comprise drugs or bio-active agents incorporated into or onto the device or stent in greater percentages than conventional devices or stents. Radiopaque materials may be incorporated into, or coated onto, the intraluminal device or stent. Precise geometries or patterns are simply and readily achievable using the laser cutting methods in the presence of an inert gas while minimizing damage to the precursor materials.
摘要翻译：激光切割生物可吸收的管腔内装置或支架以及用于形成这种管腔内装置或支架的方法。在惰性气体的存在下激光切割生物可吸收材料的前体片（100）或管（200），以形成具有期望的几何形状或图案的管腔内医疗装置或支架。装置或支架可以包括螺旋形或其它形状，其具有赋予其上的激光切割几何形状或图案。装置或支架可以进一步包含以比传统装置或支架更大的百分比掺入装置或支架中或其上的药物或生物活性剂。不透射线的材料可以并入或涂覆在腔内装置或支架上。使用激光切割方法在存在惰性气体同时最小化对前体材料的损害的情况下，可以简单且容易地实现精确的几何形状或图案。

8. 发明申请

WO2007134222A2 BALOON EXPANDABLE BIOABSORBABLE DRUG ELUTING STENT 审中-公开
标题翻译： BALOON可扩展的生物可溶性药物涂抹器
公开(公告)号：WO2007134222A2
公开(公告)日：2007-11-22
申请号：PCT/US2007/068754
申请日：2007-05-11
申请人： CORDIS CORPORATION , BURGERMEISTER, Robert , DAVE, Vipul Bhupendra , OVERAKER, David , MARREY, Ramesh
发明人： BURGERMEISTER, Robert , DAVE, Vipul Bhupendra , OVERAKER, David , MARREY, Ramesh
IPC分类号： A61F2/90
CPC分类号： A61F2/915 , A61F2/82 , A61F2002/825 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2210/0004 , A61F2220/0008 , A61F2220/0075 , A61F2230/0013 , A61F2250/0018 , A61F2250/0028 , A61F2250/0029 , A61F2250/0036 , A61F2250/0062 , A61F2250/0067 , A61F2250/0098 , A61L31/04 , A61L31/16 , A61L31/18 , A61L2300/416
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stent has a plurality of hoop components interconnected by a plurality of flexible connectors. The hoop components are formed as a continuous series of substantially longitudinally or axially oriented radial strut members and alternating substantially circumferentially oriented radial arc members. The geometry of the struts and arcs is such that when the stent is expanded, it has very high strains within a relatively small region. This strain localization results in what is often referred to as "hinging", where the hinge is the small region within which the strains are very high.
摘要翻译：生物相容性材料可以配置成任何数量的可植入医疗装置，包括腔内支架。可以使用聚合材料来制造包括支架在内的任何这些装置。支架具有通过多个柔性连接器互连的多个环部件。环形部件形成为基本纵向或轴向定向的径向支柱构件和交替的基本上周向定向的径向弧形构件的连续系列。支柱和弧的几何形状使得当支架膨胀时，其在相对小的区域内具有非常高的应变。这种应变定位导致通常被称为“铰接”，其中铰链是应变非常高的小区域。

9. 发明申请

WO2009059055A3 METHOD OF MAKING A VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：制造血管闭合装置的方法
公开(公告)号：WO2009059055A3
公开(公告)日：2010-04-15
申请号：PCT/US2008081867
申请日：2008-10-30
申请人： CORDIS CORP , DAVE VIPUL BHUPENDRA , SCALZO HOWARD , FISHER JERRY
发明人： DAVE VIPUL BHUPENDRA , SCALZO HOWARD , FISHER JERRY
IPC分类号： A61L31/04 , A61L31/14 , A61L31/16 , D01F8/04 , D04H3/00
CPC分类号： A61F2/02 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00004 , A61L31/041 , A61L31/141 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/43 , A61L2430/36 , D01D5/34 , D01F1/10 , D01F1/103 , D04H1/42 , Y10T442/2525 , Y10T442/3146 , Y10T442/3154 , Y10T442/3163 , Y10T442/3171 , Y10T442/637 , Y10T442/638 , Y10T442/64 , Y10T442/641 , Y10T442/642 , C08L75/04 , C08L67/04
摘要： A method of making a biocompatible, implantable medical device, including a vascular closure device is disclosed. The method includes forming a biocompatible polymer into at least one fiber and randomly orienting the at least one fiber into a fibrous structure having at least one interstitial spaces. Polymeric materials may be utilized to fabricate any of these devices. The polymeric materials may include additives such as drugs or other bioactive agents as well as antibacterial agents. In such instances, at least one agent, in therapeutic dosage, is incorporated into at least one of the fibrous structure and the at least one fiber.
摘要翻译：公开了制造生物相容性可植入医疗装置的方法，包括血管闭合装置。该方法包括将生物相容性聚合物形成至少一种纤维，并将至少一种纤维随机定向成具有至少一个间隙的纤维结构。可以使用聚合材料来制造任何这些装置。聚合物材料可以包括添加剂如药物或其他生物活性剂以及抗菌剂。在这种情况下，将治疗剂量中的至少一种试剂并入纤维结构和至少一种纤维中的至少一种。

10. 发明申请

WO2007082186A3 BIOABSORBABLE DRUG DELIVERY DEVICES 审中-公开
标题翻译：可生物药物递送设备
公开(公告)号：WO2007082186A3
公开(公告)日：2008-10-09
申请号：PCT/US2007060237
申请日：2007-01-08
申请人： CORDIS CORP , DAVE VIPUL BHUPENDRA
发明人： DAVE VIPUL BHUPENDRA
IPC分类号： A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61L31/16 , A61L31/10 , A61L31/148 , A61L31/18 , A61L2300/00
摘要： A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, whereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. Radiopaque markers may also be incorporated into, or onto, the devices. The devices may be generally tubular helical stents comprised of a solid ladder or an open lattice configuration, or a hybrid combination thereof. The tubular helical stents are generally formed from precursor fibers, films or tubes.
摘要翻译：生物吸收性药物输送装置及其制造方法。该装置优选由使用低温制造方法的生物可吸收材料形成，由此将药物或其它生物活性剂掺入到装置中或装置上，并且在加工过程中药物或其它试剂的降解最小化。不透射线的标记也可以并入设备中或装入设备中。这些装置可以是通常为管状螺旋支架，其由固体梯子或开放晶格构型组成，或其混合组合。管状螺旋支架通常由前体纤维，膜或管形成。

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