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1. 发明申请

WO2007115198A2 COMPLIANT ELECTRICAL STIMULATION LEADS AND METHODS OF FABRICATION 审中-公开
标题翻译：合适的电刺激引线和制造方法
公开(公告)号：WO2007115198A2
公开(公告)日：2007-10-11
申请号：PCT/US2007/065677
申请日：2007-03-30
申请人： ADVANCED NEUROMODULATION SYSTEMS, INC. , DAGLOW, Terry, D. , FRANZ, Brian
发明人： DAGLOW, Terry, D. , FRANZ, Brian
IPC分类号： A61K31/47
CPC分类号： A61N1/0551 , A61N1/0504 , A61N1/0558 , Y10T29/49208
摘要： In one embodiment, a neurostimulation lead (100) for stimulating neural tissue of a patient, comprises: a lead body (106) of insulative material; a plurality of electrodes (110); a plurality of terminals (114); a plurality of conductors (201), wherein the plurality of electrodes are electrically coupled to the plurality of terminals through the plurality of conductors; wherein the plurality of conductors are disposed in a helical manner in a repeating pattern of groups of conductors separated by gaps (204) along a substantial length of the lead body, each gap being larger than an inter-conductor pitch within the groups of conductors; wherein the insulative material is a compliant material permitting elongation of the lead at low stretching forces and the insulative material of the lead body is fused through a substantial volume of the lead body and along a substantial length of the lead body.
摘要翻译：在一个实施例中，用于刺激患者的神经组织的神经刺激引线（100）包括：绝缘材料的引线体（106）; 多个电极（110）; 多个端子（114）; 多个导体（201），其中所述多个电极通过所述多个导体电耦合到所述多个端子; 其中所述多个导体以螺旋方式设置成沿着所述引线体的实质长度由间隙（204）分开的导体组的重复图案，每个间隙大于所述导体组内的导体间间距; 其中所述绝缘材料是允许所述引线在低拉伸力下延伸的顺应性材料，并且所述引线体的绝缘材料通过所述引线体的大体积并沿着所述引线体的相当长度被熔合。

2. 发明申请

WO2005053789A3 DIRECTIONAL STIMULATION LEAD AND ORIENTATION SYSTEM, AND IMPROVED PERCUTANEOUS-INSERTION NEEDLE AND METHOD OF IMPLANTING A LEAD 审中-公开
标题翻译：定向刺激引导和定向系统，以及改进的经皮插入针和植入引线的方法
公开(公告)号：WO2005053789A3
公开(公告)日：2005-08-04
申请号：PCT/US2004039425
申请日：2004-11-24
申请人： ADVANCED NEUROMODULATION SYS , DAGLOW TERRY , FRANZ BRIAN , ERICKSON JOHN H , HOOPER SANDY , JONES TIM
发明人： DAGLOW TERRY , FRANZ BRIAN , ERICKSON JOHN H , HOOPER SANDY , JONES TIM
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/0529
摘要： A lead, method of manufacturing same, and system for stimulation is provided. The lead (10) includes an insulative member or layer (50a, 50b) that masks a portion of the electrode(s) (18) to effectively generate a directional lead that focuses or directs the stimulation to desired location(s). In another embodiment, the lead further includes a marking system (600) to allow a clinician to orient the directional lead, as desired, while the lead is within a body. An improved needle (800) for use in percutaneous insertion of a lead, and method for insertion of same, is provided. The needle includes a flare or lip (812) on the needle heel (814) proximate the needle orifice (808).
摘要翻译：提供了一种引线，制造该引线的方法和用于刺激的系统。引线（10）包括遮蔽一个或多个电极（18）的一部分的绝缘构件或层（50a，50b）以有效地产生定向引线，该定向引线将刺激聚焦或引导至期望位置。在另一个实施例中，引线还包括标记系统（600），以允许临床医生根据需要定向定向引线，同时引线位于身体内。提供了一种用于经皮插入引线的改进的针（800）及其插入方法。针在靠近针孔（808）的针踵（814）上包括喇叭口或唇（812）。

3. 发明申请

WO2011143315A3 TORQUE WRENCH 审中-公开
公开(公告)号：WO2011143315A3
公开(公告)日：2011-11-17
申请号：PCT/US2011/036082
申请日：2011-05-11
申请人： DAGLOW, Terry
发明人： DAGLOW, Terry
IPC分类号： A61B19/00 , B25B21/00 , B25B19/00 , A61F2/00 , A61B17/84
摘要： A torque wrench comprising a shaft with a longitudinal axis; wherein the shaft has a lower end and an upper end, the lower end being configured to engage a fastener. A shaft cam is configured to rotate with the shaft around the longitudinal axis. A groove is defined in the shaft cam, the groove comprising a groove upper surface. A ramp is positioned within the groove at a position below the groove upper surface, wherein the ramp comprises a ramp upper surface that is at an angle with respect to the longitudinal axis. A housing surrounds the shaft and shaft cam. The wrench comprises an outer cam comprising an engaging member extending within the housing, wherein the engaging member is configured to selectively contact ramp upper surface or groove upper surface. The wrench also comprises a spring configured to apply a downward force on the outer cam, such that the outer cam tends to prevent the shaft cam from rotating when the upper surface of the ramp is in contact with the engaging member of the outer cam. A void is defined in the groove between the ramp and a side wall of the groove, the void being configured to allow the engaging member to escape the groove when it is not constrained by the ramp.

4. 发明申请

WO2005053789A2 DIRECTIONAL STIMULATION LEAD AND ORIENTATION SYSTEM, AND IMPROVED PERCUTANEOUS-INSERTION NEEDLE AND METHOD OF IMPLANTING A LEAD 审中-公开
标题翻译：方向刺激引导和定向系统，以及改进的PERCUTANEOUS插入针和引导方法
公开(公告)号：WO2005053789A2
公开(公告)日：2005-06-16
申请号：PCT/US2004/039425
申请日：2004-11-24
申请人： ADVANCED NEUROMODULATION SYSTEMS, INC. , DAGLOW, Terry , FRANZ, Brian , ERICKSON, John, H. , HOOPER, Sandy , JONES, Tim
发明人： DAGLOW, Terry , FRANZ, Brian , ERICKSON, John, H. , HOOPER, Sandy , JONES, Tim
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/0529
摘要： A lead, method of manufacturing same, and system for stimulation is provided. The lead (10) includes an insulative member or layer (50a, 50b) that masks a portion of the electrode(s) (18) to effectively generate a directional lead that focuses or directs the stimulation to desired location(s). In another embodiment, the lead further includes a marking system (600) to allow a clinician to orient the directional lead, as desired, while the lead is within a body. An improved needle (800) for use in percutaneous insertion of a lead, and method for insertion of same, is provided. The needle includes a flare or lip (812) on the needle heel (814) proximate the needle orifice (808).
摘要翻译：提供铅，制造方法和刺激系统。引线（10）包括掩蔽电极（18）的一部分的绝缘部件或层（50a，50b），以有效地产生将刺激聚焦或引导到所需位置的方向引线。在另一个实施例中，引线还包括标记系统（600），以允许临床医生根据需要定向引导线，同时引线在体内。提供了用于经皮插入引线的改进的针（800）及其插入方法。该针包括靠近针孔（808）的针脚跟（814）上的喇叭口或唇缘（812）。

5. 发明申请

WO2006113593A2 ELECTRICAL STIMULATION LEAD, SYSTEM, AND METHOD 审中-公开
标题翻译：电刺激，系统和方法
公开(公告)号：WO2006113593A2
公开(公告)日：2006-10-26
申请号：PCT/US2006/014351
申请日：2006-04-13
申请人： ADVANCED NEUROMODULATION SYSTEMS, INC. , NORTH, Richard, B. , DAGLOW, Terry, D. , GOLDMAN, Stephen, L.
发明人： NORTH, Richard, B. , DAGLOW, Terry, D. , GOLDMAN, Stephen, L.
IPC分类号： A61N1/00
CPC分类号： A61N1/0553 , A61N1/08 , A61N1/36071
摘要： In one embodiment, a paddle lead comprises: a plurality of stimulating electrode contacts disposed, the plurality of stimulation electrode contacts being adapted to allow the stimulation paddle to flex transversely about a longitudinal axis; wherein the plurality of stimulation electrode contacts are arranged in at least first, second, and third rows that are disposed perpendicular to a longitudinal axis of the paddle; the first and third rows respectively having multiple electrode contacts electrically coupled to different conductors of the lead to enable the multiple electrode contacts of the first and third rows to function in independent cathode states, anode states, or high-impedance states; the second row being disposed between the first and third rows, the second row having multiple electrode contacts each electrically coupled to a common conductor to cause the multiple electrode contacts of the second row to function in a common cathode state, anode state, or high-impedance state.
摘要翻译：在一个实施例中，桨引线包括：多个刺激电极触点，所述多个刺激电极触点适于允许刺激桨相对于纵向轴线横向弯曲; 其中所述多个刺激电极触点布置在垂直于所述桨的纵向轴线设置的至少第一，第二和第三行中; 所述第一和第三行分别具有电耦合到所述引线的不同导体的多个电极接触，以使得所述第一和第三行的多个电极接触能够在独立的阴极状态，阳极状态或高阻抗状态下起作用; 第二排布置在第一和第三行之间，第二行具有多个电极接触件，每个电极接触部分电耦合到公共导体，以使第二行的多个电极接触在公共阴极状态，阳极状态或高压状态下起作用，阻抗状态。

6. 发明申请

WO2005016447A3 APPARATUS AND METHOD FOR IMPLANTING AN ELECTRICAL STIMULATION SYSTEM AND A PADDLE STYLE ELECTRICAL STIMULATION LEAD 审中-公开
标题翻译：用于植入电刺激系统和平板式电刺激引线的装置和方法
公开(公告)号：WO2005016447A3
公开(公告)日：2005-12-15
申请号：PCT/US2004024552
申请日：2004-07-28
申请人： ADVANCED NEUROMODULATION SYS , DAGLOW TERRY
发明人： DAGLOW TERRY
IPC分类号： A61N1/05 , A61N1/34
CPC分类号： A61B17/3415 , A61B17/3401 , A61B17/3468 , A61N1/0553 , A61N1/36017 , A61N1/3605
摘要： In one embodiment, an introducer is provided for implanting an electrical stimulation lead to enable electrical stimulation of nerve tissue. The introducer includes an outer sheath and an inner penetrator. The outer sheath is configured to accommodate insertion of the electrical stimulation lead through the outer sheath and may be inserted into a human body near the nerve tissue. The inner penetrator is removably housed within the outer sheath and includes an inner channel configured to accommodate a guide wire. The inner penetrator may be advanced along the guide wire to a desired location relative to the nerve tissue and removed from the outer sheath leaving the outer sheath substantially in position for insertion of the electrical stimulation lead through the outer sheath into position proximate the nerve tissue.
摘要翻译：在一个实施例中，提供导引器用于植入电刺激引线以使电刺激神经组织。引导器包括外护套和内穿透器。外护套构造成适应电刺激引线穿过外护套的插入，并且可以插入神经组织附近的人体内。内穿透器可移除地容纳在外护套内并且包括构造成容纳导丝的内通道。内穿透器可以沿着引导线前进到相对于神经组织的期望位置，并从外护套移除，使外护套基本上位于其中，以将电刺激引线穿过外护套插入靠近神经组织的位置。

7. 发明申请

WO2005016447A2 APPARATUS AND METHOD FOR IMPLANTING AN ELECTRICAL STIMULATION SYSTEM AND A PADDLE STYLE ELECTRICAL STIMULATION LEAD 审中-公开
标题翻译：装置和方法用于植入电刺激系统和平板式电刺激引线
公开(公告)号：WO2005016447A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/024552
申请日：2004-07-28
申请人： ADVANCED NEUROMODULATION SYSTEMS, INC. , DAGLOW, Terry
发明人： DAGLOW, Terry
IPC分类号： A61N1/05
CPC分类号： A61B17/3415 , A61B17/3401 , A61B17/3468 , A61N1/0553 , A61N1/36017 , A61N1/3605
摘要： In one embodiment, an introducer is provided for implanting an electrical stimulation lead to enable electrical stimulation of nerve tissue. The introducer includes an outer sheath and an inner penetrator. The outer sheath is configured to accommodate insertion of the electrical stimulation lead through the outer sheath and may be inserted into a human body near the nerve tissue. The inner penetrator is removably housed within the outer sheath and includes an inner channel configured to accommodate a guide wire. The inner penetrator may be advanced along the guide wire to a desired location relative to the nerve tissue and removed from the outer sheath leaving the outer sheath substantially in position for insertion of the electrical stimulation lead through the outer sheath into position proximate the nerve tissue.
摘要翻译：在一个实施例中，提供导引器用于植入电刺激导线以使得能够电刺激神经组织。导入器包括外部护套和内部穿透器。外护套被构造成适应电刺激引线插入穿过外护套，并且可以被插入神经组织附近的人体中。内部穿透器可移除地容纳在外部护套内并且包括构造成容纳导丝的内部通道。内部穿透器可以沿着导丝前进到相对于神经组织的期望位置并且从外部护套移除，从而使外部护套基本就位，以用于将电刺激导线插入穿过外部护套到接近神经组织的位置中。

8. 发明申请

WO2010019827A1 METHOD AND DEVICE FOR IMPLANTING A MEDICAL IMPLANT TO TREAT HEARING LOSS IN A PATIENT 审中-公开
标题翻译：用于植入医疗植入物以治疗患者听力损失的方法和装置
公开(公告)号：WO2010019827A1
公开(公告)日：2010-02-18
申请号：PCT/US2009/053791
申请日：2009-08-13
申请人： DAGLOW, Terry, D.
发明人： DAGLOW, Terry, D.
IPC分类号： A61N1/00
CPC分类号： A61F2/18 , A61F2002/183 , H04R25/606 , H04R2225/67
摘要： In one embodiment, a method of treating hearing loss in a patient, comprises: creating a first channel in osseous tissue at or immediately adjacent to the promontory of the patient; creating a second channel through the first channel to the scala tympani or the scala vestibuli; and implanting a hearing device in the first channel, the hearing device being in fluid communication with cochlear fluid through the second channel, the hearing device being adapted to drive cochlear fluid to activate auditory receptor cells in the cochlea of the patient.
摘要翻译：在一个实施例中，一种治疗患者的听力损失的方法包括：在患者的海角处或紧邻邻近的骨组织中产生第一通道; 通过第一个渠道创建第二个渠道到Scala鼓掌或scala vestibuli; 以及在所述第一通道中植入听力装置，所述听力装置与通过所述第二通道的耳蜗流体流体连通，所述听力装置适于驱动耳蜗流体以激活所述患者耳蜗中的听觉受体细胞。

9. 发明申请

WO2006113593A3 ELECTRICAL STIMULATION LEAD, SYSTEM, AND METHOD 审中-公开
标题翻译：电刺激，系统和方法
公开(公告)号：WO2006113593A3
公开(公告)日：2007-07-12
申请号：PCT/US2006014351
申请日：2006-04-13
申请人： ADVANCED NEUROMODULATION SYS , NORTH RICHARD B , DAGLOW TERRY D , GOLDMAN STEPHEN L
发明人： NORTH RICHARD B , DAGLOW TERRY D , GOLDMAN STEPHEN L
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/08 , A61N1/36071
摘要： In one embodiment, a paddle lead comprises: a plurality of stimulating electrode contacts disposed, the plurality of stimulation electrode contacts being adapted to allow the stimulation paddle to flex transversely about a longitudinal axis; wherein the plurality of stimulation electrode contacts are arranged in at least first, second, and third rows that are disposed perpendicular to a longitudinal axis of the paddle; the first and third rows respectively having multiple electrode contacts electrically coupled to different conductors of the lead to enable the multiple electrode contacts of the first and third rows to function in independent cathode states, anode states, or high-impedance states; the second row being disposed between the first and third rows, the second row having multiple electrode contacts each electrically coupled to a common conductor to cause the multiple electrode contacts of the second row to function in a common cathode state, anode state, or high-impedance state.
摘要翻译：在一个实施例中，桨引线包括：多个刺激电极触点，所述多个刺激电极触点适于允许刺激桨相对于纵向轴线横向弯曲; 其中所述多个刺激电极触点布置在垂直于所述桨的纵向轴线设置的至少第一，第二和第三行中; 所述第一和第三行分别具有电耦合到所述引线的不同导体的多个电极接触，以使得所述第一和第三行的多个电极接触能够在独立的阴极状态，阳极状态或高阻抗状态下起作用; 第二排布置在第一和第三行之间，第二行具有多个电极接触件，每个电极接触部分电耦合到公共导体，以使第二行的多个电极接触在公共阴极状态，阳极状态或高压状态下起作用，阻抗状态。

10. 发明申请

WO2006119135A2 METHOD AND APPARATUS FOR IMPLANTING AN ELECTRICAL STIMULATION LEAD USING A FLEXIBLE INTRODUCER 审中-公开
标题翻译：使用柔性引导器植入电刺激的方法和装置
公开(公告)号：WO2006119135A2
公开(公告)日：2006-11-09
申请号：PCT/US2006016512
申请日：2006-04-28
申请人： ADVANCED NEUROMODULATION SYS , DAGLOW TERRY D , JONES TIMOTHY S , HEGI PETER B , HICKMAN THOMAS K
发明人： DAGLOW TERRY D , JONES TIMOTHY S , HEGI PETER B , HICKMAN THOMAS K
IPC分类号： A61N1/05 , A61N1/34
CPC分类号： A61N1/0553 , A61B17/3401 , A61B17/3415 , A61B17/3468 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： In one embodiment, an introducer is provided for implanting a paddle style electrical stimulation lead to enable electrical stimulation of nerve tissue. The introducer includes an outer sheath and an inner penetrator. The outer sheath may accommodate insertion of the paddle style electrical stimulation lead and may be inserted into a human body near the nerve tissue. The inner penetrator is removably housed within the outer sheath and includes an inner channel configured to accommodate a guide wire, a tip end having a shape and size substantially conforming to that of the guide wire, a body region having a shape and size substantially conforming to that of the outer sheath, and one or more transition regions substantially connecting the tip end with the body region. The inner penetrator may be advanced along the guide wire to a desired location relative to the nerve tissue and removed from the outer sheath leaving the outer sheath substantially in position for insertion of the paddle style electrical stimulation lead through the outer sheath into position proximate the nerve tissue. At least a portion of the transition regions of the inner penetrator may flex to substantially follow flexures in the guide wire during advancement of the inner penetrator.
摘要翻译：在一个实施例中，提供导引器用于植入桨式电刺激引线以使得能够电刺激神经组织。引导器包括外护套和内穿透器。外护套可以容纳桨式电刺激引线的插入，并且可以插入神经组织附近的人体内。内穿透器可移除地容纳在外护套内并且包括构造成容纳导丝的内通道，其具有基本上与导丝的形状和尺寸基本一致的形状和尺寸的末端，具有基本上符合外护套，以及一个或多个过渡区域基本上将前端与身体区域连接。内穿透器可以沿着引导线前进到相对于神经组织的期望位置，并且从外护套移除，使外护套基本上位于其中，以便将桨式电刺激引线穿过外护套插入靠近神经的位置组织。内穿透器的过渡区域的至少一部分可以在内穿透器的推进期间弯曲以基本上跟随导丝中的弯曲。

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