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1. 发明申请

WO2012164386A3 TRAFFIC CONTROL METHOD AND TRAFFIC CONTROL APPARATUS 审中-公开
公开(公告)号：WO2012164386A3
公开(公告)日：2012-12-06
申请号：PCT/IB2012/001075
申请日：2012-05-22
申请人： ALCATEL LUCENT , LUO, Haibin , QIU, Wei , CUI, Jian
发明人： LUO, Haibin , QIU, Wei , CUI, Jian
IPC分类号： G06F17/30
摘要： The present invention discloses a traffic control method and a traffic control apparatus. The traffic control method comprising the steps of collecting key performance indexes of a system; and determining whether to limit requests entering into the system based on the collected key performance Indexes of the system, and it is determined that the requests entering into the system will be limited when a certain collected key performance Index of the system is inferior to a first threshold for a period of time, According to the invention, traffic control may be effectively, practically and flexibly provided to a system.

2. 发明申请

WO2012121611A3 MEAT HYDROLYSATES 审中-公开
标题翻译：肉类水解物
公开(公告)号：WO2012121611A3
公开(公告)日：2012-11-01
申请号：PCT/NZ2012000026
申请日：2012-03-02
申请人： MEAT BIOLOG RES LTD , DAS SHANTANU , SINGH HARJINDER , MOUGHAN PAUL JAMES , HENARE SHARON JAMES , CUI JIAN , WILKINSON BRIAN HERBERT PATRICK , CHONG ROBERT
发明人： DAS SHANTANU , SINGH HARJINDER , MOUGHAN PAUL JAMES , HENARE SHARON JAMES , CUI JIAN , WILKINSON BRIAN HERBERT PATRICK , CHONG ROBERT
IPC分类号： A23J1/02 , A23J3/34 , A23L1/305
CPC分类号： A23J3/341 , A23L33/18
摘要： This invention relates to a hydrolysate composition isolated from a meat source characterised in that, the hydrolysate contains 60 to 90% w/w protein which has a moisture level of below 20%. The meat source is preferably obtained from lamb and the hydrolysate preferably consists predominantly of peptides of molecular weight less than 1000 Daltons and contains less than 10% w/w of fat.
摘要翻译：本发明涉及从肉源分离的水解产物组合物，其特征在于，水解产物含有水分含量低于20％的60-90％w / w蛋白质。肉源优选地从羊肉获得，并且水解产物优选主要由分子量小于1000道尔顿且含有小于10％w / w脂肪的肽组成。

3. 发明申请

WO2008021896A8 THERAPEUTIC METHODS FOR NEUROPATHIC PAIN 审中-公开
标题翻译：神经性疼痛的治疗方法
公开(公告)号：WO2008021896A8
公开(公告)日：2008-12-18
申请号：PCT/US2007075500
申请日：2007-08-08
申请人： UNIV LOUISIANA STATE , BAZAN NICOLAS G , CUI JIAN-GUO
发明人： BAZAN NICOLAS G , CUI JIAN-GUO
IPC分类号： A61K38/00 , A61K38/17
CPC分类号： A61K38/1709 , G01N33/5058 , G01N2333/4722 , G01N2800/2842
摘要： The agrin protein was shown to be important in preventing the development of neuropathic pain, as well as in treating neuropathic pain. Both agrin protein and gene expression were shown to be down-regulated in mammals with neuropathic pain. Increasing either agrin gene expression or protein resulted in a decrease in the development of neuropathic pain. Agrin protein or the C-terminal agrin fragments can be administered in a number of ways, preferably by intrathecal injection. In addition, agrin can be increased by administering a compound shown to affect agrin gene expression or agrin protein concentration, e.g., SCP-I and SCP-Ml (also known as JMM). Agrin protein decrease was shown to be prevented by administering an NMDA receptor antagonist, e.g., MK801. Agrin and a C-terminal agrin fragment also induced phosphorylation of the NMDA receptor subunit NR1 at the serine residue site which led to suppression of neuropathic pain.
摘要翻译：证明集聚蛋白对于预防神经性疼痛的发展以及治疗神经性疼痛是重要的。在神经性疼痛的哺乳动物中，聚集蛋白蛋白和基因表达都显示出下调。增加集聚蛋白基因表达或蛋白质导致神经性疼痛发展的减少。可以以多种方式施用Agrin蛋白或C端集聚蛋白片段，优选通过鞘内注射。另外，通过施用显示影响集聚蛋白基因表达或集聚蛋白浓度的化合物，例如SCP-1和SCP-M1（也称为JMM），可以增加集聚蛋白。表明通过施用NMDA受体拮抗剂例如MK801可以防止Agrin蛋白减少。 Agrin和C-末端集聚蛋白片段也在丝氨酸残基位点诱导了NMDA受体亚基NR1的磷酸化，导致抑制神经性疼痛。

4. 发明申请

WO2006076415A3 EXO- AND DIASTEREO- SELECTIVE SYNTHESES OF HIMBACINE ANALOGS 审中-公开
标题翻译：乙酰胺类似物的外 - 和二选择性合成
公开(公告)号：WO2006076415A3
公开(公告)日：2006-11-16
申请号：PCT/US2006000954
申请日：2006-01-12
申请人： SCHERING CORP , WU GEORGE G , SUDHAKAR ANANTHA , WANG TAO , XIE JI , CHEN FRANK XING , POIRIER MARC , HUANG MINGSHENG , SABESAN VIJAY , KWOK DAW-LONG , CUI JIAN , YANG XIAOJING , THIRUVENGADAM TIRUVETTIPURAM K , LIAO JING , ZAVIALOV ILIA , NGUYEN HOA N , LIM NGIAP KIE
发明人： WU GEORGE G , SUDHAKAR ANANTHA , WANG TAO , XIE JI , CHEN FRANK XING , POIRIER MARC , HUANG MINGSHENG , SABESAN VIJAY , KWOK DAW-LONG , CUI JIAN , YANG XIAOJING , THIRUVENGADAM TIRUVETTIPURAM K , LIAO JING , ZAVIALOV ILIA , NGUYEN HOA N , LIM NGIAP KIE
IPC分类号： C07D307/92 , C07C69/54 , C07C69/606 , C07C205/44 , C07C205/55 , C07C235/28 , C07C309/08 , C07D235/12 , C07D263/56 , C07D277/64 , C07D405/06 , C07D413/06 , C07D417/06 , C07F9/58
CPC分类号： C07D263/56 , C07C69/606 , C07C69/732 , C07C201/10 , C07C201/12 , C07C205/44 , C07C205/55 , C07C231/10 , C07C231/12 , C07C235/28 , C07C303/32 , C07C309/08 , C07C2601/16 , C07D277/64 , C07D307/92 , C07D333/56 , C07D405/06 , C07D413/06 , C07D417/06 , C07F7/1852 , C07F9/582 , Y02P20/55 , C07C233/28
摘要： The application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by the following. (I)
摘要翻译：本申请公开了一种制备可用作凝血酶受体拮抗剂的烟肼类似物的新方法。该方法部分基于使用手性硝基中心的碱促进的动态差向异构化。本文教导的化学结构可以举例说明如下。（一世）

5. 发明申请

WO2012164386A2 TRAFFIC CONTROL METHOD AND TRAFFIC CONTROL APPARATUS 审中-公开
标题翻译：交通控制方法和交通控制装置
公开(公告)号：WO2012164386A2
公开(公告)日：2012-12-06
申请号：PCT/IB2012001075
申请日：2012-05-22
申请人： ALCATEL LUCENT , LUO HAIBIN , QIU WEI , CUI JIAN
发明人： LUO HAIBIN , QIU WEI , CUI JIAN
CPC分类号： H04L47/822 , H04L47/29 , H04L47/745
摘要： The present invention discloses a traffic control method and a traffic control apparatus. The traffic control method comprising the steps of collecting key performance indexes of a system; and determining whether to limit requests entering into the system based on the collected key performance Indexes of the system, and it is determined that the requests entering into the system will be limited when a certain collected key performance Index of the system is inferior to a first threshold for a period of time, According to the invention, traffic control may be effectively, practically and flexibly provided to a system.
摘要翻译：本发明公开了一种交通控制方法和交通控制装置。所述流量控制方法包括收集系统的关键性能指标的步骤; 并且基于所收集的系统的关键性能指标来确定是否限制进入系统的请求，并且当系统的某个收集的关键性能指标低于第一个时，确定进入系统的请求将受到限制阈值一段时间，根据本发明，可以有效地，实际地和灵活地向业务系统提供业务控制。

6. 发明申请

WO2010028232A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS 审中-公开
标题翻译：合成8 - [{1-（3,5-双 - （三氟甲基）苯基） - 乙基} - 甲基] -8-苯基-1,7-二氮杂螺[4.5]癸-2-醇的方法和中间体一个化合物
公开(公告)号：WO2010028232A1
公开(公告)日：2010-03-11
申请号：PCT/US2009/056020
申请日：2009-09-04
申请人： SCHERING CORPORATION , WU, George, G. , WERNE, Gerald , FU, Xiaoyong , ORR, Robert, K. , CHEN, Frank, Xing , CUI, Jian , SPRAGUE, Victoria, M. , ZHANG, Fucheng , XIE, Ji , ZENG, Liansheng , CASTELLANOS, Louis, Peter , CHEN, Yuyin , POIRIER, Marc , MERGELSBERG, Ingrid
发明人： WU, George, G. , WERNE, Gerald , FU, Xiaoyong , ORR, Robert, K. , CHEN, Frank, Xing , CUI, Jian , SPRAGUE, Victoria, M. , ZHANG, Fucheng , XIE, Ji , ZENG, Liansheng , CASTELLANOS, Louis, Peter , CHEN, Yuyin , POIRIER, Marc , MERGELSBERG, Ingrid
IPC分类号： C07D207/26 , C07D471/10 , C07D498/04
CPC分类号： C07D471/10 , C07C217/46 , C07C217/48 , C07D207/26 , C07D207/267 , C07D207/28 , C07D498/04
摘要： This application discloses a novel process to synthesize 8-[{1-(3,5-Bis- (trifluoromethyl)phenyl)-ethoxy}-nnethyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations intermediates useful in said process, and processes for preparing said intermediates; also disclosed is a process for removal of metals from N-heterocyclic carbine metal complexes. IM=102123
摘要翻译：该申请公开了合成8 - [{1-（3,5-双 - （三氟甲基）苯基） - 乙氧基} - 乙基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸烷-2 一种可用于例如可用于所述方法的药物制剂中间体中的NK-1抑制剂化合物的化合物，以及制备所述中间体的方法; 还公开了从N-杂环卡宾金属络合物中除去金属的方法。 IM = 102123

7. 发明申请

WO2012121611A2 EDIBLE COMPOSITION AND METHOD OF MANUFACTURE 审中-公开
标题翻译：可食用组合物和制造方法
公开(公告)号：WO2012121611A2
公开(公告)日：2012-09-13
申请号：PCT/NZ2012/000026
申请日：2012-03-02
申请人： MEAT BIOLOGICS RESEARCH LIMITED , DAS, Shantanu , SINGH, Harjinder , MOUGHAN, Paul James , HENARE, Sharon James , CUI, Jian , WILKINSON, Brian Herbert Patrick , CHONG, Robert
发明人： DAS, Shantanu , SINGH, Harjinder , MOUGHAN, Paul James , HENARE, Sharon James , CUI, Jian , WILKINSON, Brian Herbert Patrick , CHONG, Robert
IPC分类号： A23J3/34
CPC分类号： A23J3/341 , A23L33/18
摘要： This invention relates to a hydrolysate composition isolated from a meat source characterised in that, the hydrolysate contains 60 to 90% w/w protein which has a moisture level of below 20%.
摘要翻译：本发明涉及从肉源分离的水解产物组合物，其特征在于，水解产物含有水分含量低于20％的60-90％w / w蛋白质。

8. 发明申请

WO2012121613A3 MEAT HYDROLYSATES FOR FOOD FLAVORING AND MEDICAMENTS 审中-公开
标题翻译：食用油脂和药物的水解物
公开(公告)号：WO2012121613A3
公开(公告)日：2012-11-01
申请号：PCT/NZ2012000028
申请日：2012-03-02
申请人： MEAT BIOLOG RES LTD , DAS SHANTANU , SINGH HARJINDER , MOUGHAN PAUL JAMES , HENARE SHARON JAMES , CUI JIAN , WILKINSON BRIAN HERBERT PATRICK , CHONG ROBERT
发明人： DAS SHANTANU , SINGH HARJINDER , MOUGHAN PAUL JAMES , HENARE SHARON JAMES , CUI JIAN , WILKINSON BRIAN HERBERT PATRICK , CHONG ROBERT
IPC分类号： A61K38/01 , A23L1/305 , A23L1/313 , A61K38/06 , A61K38/08
CPC分类号： A61K38/012
摘要： This invention relates to the use of a hydrolysate composition isolated from a meat source and containing 60 to 90% w/w protein, in the manufacture of a medicament, to treat amino acid malnourishment or an associated condition in an animal.
摘要翻译：本发明涉及从肉源分离并含有60-90％w / w蛋白质的水解物组合物在制备药物中用于治疗动物中的氨基酸营养不良或相关病症的用途。

9. 发明申请

WO2012121613A2 USE OF EDIBLE COMPOSITION 审中-公开
标题翻译：食用组合物的使用
公开(公告)号：WO2012121613A2
公开(公告)日：2012-09-13
申请号：PCT/NZ2012/000028
申请日：2012-03-02
申请人： MEAT BIOLOGICS RESEARCH LIMITED , DAS, Shantanu , SINGH, Harjinder , MOUGHAN, Paul James , HENARE, Sharon James , CUI, Jian , WILKINSON, Brian Herbert Patrick , CHONG, Robert
发明人： DAS, Shantanu , SINGH, Harjinder , MOUGHAN, Paul James , HENARE, Sharon James , CUI, Jian , WILKINSON, Brian Herbert Patrick , CHONG, Robert
IPC分类号： A61K38/01
CPC分类号： A61K38/012
摘要： This invention relates to the use of a hydrolysate composition isolated from a meat source and containing 60 to 90% w/w protein, in the manufacture of a medicament, to treat amino acid malnourishment or an associated condition in an animal.
摘要翻译：本发明涉及从肉源分离并含有60-90％w / w蛋白质的水解物组合物在制备药物中用于治疗动物中的氨基酸营养不良或相关病症的用途。

10. 发明申请

WO2012121612A1 METHOD OF MANUFACTURE OF AN EDIBLE COMPOSITION 审中-公开
标题翻译：可食用组合物的制备方法
公开(公告)号：WO2012121612A1
公开(公告)日：2012-09-13
申请号：PCT/NZ2012/000027
申请日：2012-03-02
申请人： MEAT BIOLOGICS RESEARCH LIMITED , DAS, Shantanu , SINGH, Harjinder , MOUGHAN, Paul James , HENARE, Sharon James , CUI, Jian , WILKINSON, Brian Herbert Patrick , CHONG, Robert
发明人： DAS, Shantanu , SINGH, Harjinder , MOUGHAN, Paul James , HENARE, Sharon James , CUI, Jian , WILKINSON, Brian Herbert Patrick , CHONG, Robert
IPC分类号： A23J3/34 , A23J1/02
CPC分类号： A23J3/341 , A23L33/18
摘要： This invention relates to a method of preparing a hydrolysate composition from a meat source, including the steps of: a) hydrolysing at least one type of protein in the meat source, at least partly due to the use of at least one protease. b) restricting the hydrolysis process for a period of between 2 to 5 hours by deactivating the protease to form a hydrolysate mixture, characterised by the further step of c) sourcing the protein from mechanically separated meat.
摘要翻译：本发明涉及从肉源制备水解产物组合物的方法，包括以下步骤：a）至少部分地由于使用至少一种蛋白酶，在肉源中水解至少一种类型的蛋白质。 b）通过使蛋白酶失活来限制水解过程2至5小时以形成水解产物混合物，其特征在于进一步的步骤，c）从机械分离的肉中得到蛋白质。

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