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1. 发明申请

WO2013181585A3 METHODS RELATED TO ADALIMUMAB 审中-公开
标题翻译：与ADALIMUMAB相关的方法
公开(公告)号：WO2013181585A3
公开(公告)日：2014-03-06
申请号：PCT/US2013043693
申请日：2013-05-31
申请人： MOMENTA PHARMACEUTICALS INC , COLLINS BRIAN EDWARD
发明人： COLLINS BRIAN EDWARD , ROBBLEE JOHN , KAUNDINYA GANESH , BOSQUES CARLOS J
IPC分类号： C40B30/04 , C12P21/06 , C40B20/08
CPC分类号： C07K16/241 , C07K2317/21 , G01N33/577 , G01N33/6854 , G01N2333/4728 , G01N2333/525 , G01N2440/38
摘要： Production and bioanalytical characterization of determinative parameters of adalimumab is presented.
摘要翻译：提出了阿达木单抗的确定参数的生产和生物分析。

2. 发明申请

WO2012162160A1 MODIFIED GLYCOPROTEINS 审中-公开
标题翻译：改性糖蛋白
公开(公告)号：WO2012162160A1
公开(公告)日：2012-11-29
申请号：PCT/US2012/038628
申请日：2012-05-18
申请人： MOMENTA PHARMACEUTICALS, INC. , BULIK, Dorota, A. , BOSQUES, Carlos, J. , COLLINS, Brian, Edward , HAINS, Maurice, Gaston , WASHBURN, Nathaniel, J. , MEADOR, James , SMITH, Sean , BHATNAGAR, Naveen
发明人： BULIK, Dorota, A. , BOSQUES, Carlos, J. , COLLINS, Brian, Edward , HAINS, Maurice, Gaston , WASHBURN, Nathaniel, J. , MEADOR, James , SMITH, Sean , BHATNAGAR, Naveen
IPC分类号： C07K16/00 , C12P21/08
CPC分类号： C07K14/70521 , C07K16/00 , C07K2317/41 , C07K2319/30 , C07K2319/40 , C07K2319/74 , C07K2319/91
摘要： Sulfated glycoproteins, and methods of making and using such sulfated glycoproteins, are described.
摘要翻译：描述了硫酸化糖蛋白，以及制备和使用这些硫酸化糖蛋白的方法。

3. 发明申请

WO2011130862A1 METHOD AND DEVICES FOR ROUTING IN A SATELLITE-BASED COMMUNICATION SYSTEM 审中-公开
标题翻译：用于在基于卫星通信系统中路由的方法和设备
公开(公告)号：WO2011130862A1
公开(公告)日：2011-10-27
申请号：PCT/CH2010/000107
申请日：2010-04-20
申请人： ABBEY TECHNOLOGY GMBH , COLLINS, Brian , DZIEDZIC, Claude
发明人： COLLINS, Brian , DZIEDZIC, Claude
IPC分类号： H04B7/185
CPC分类号： H04B7/18508 , H04B7/1856 , H04L12/4612 , H04W40/00 , H04W40/02
摘要： A satellite-based communication system (1) comprises a router system (6) which receives from a switching unit (3) via a satellite system (4) network addressing information associated with communication terminals (2) connected to the switching unit (3). The network addressing information of the communication terminals (2) are stored in the router system (6) assigned to telephone numbers associated with the communication terminals (2). For enabling an exchange unit (7) to route via the satellite link (40) received data to the communication terminal (2), the router system (6) transmits to the exchange unit (7) the network addressing information associated with the communication terminals (2) connected to the switching unit (3). Hence, data can be routed flexibly in the satellite-based communication system (1) between communication terminals (2, 2') which are not configured for satellite communication and which are used by mobile users who may move in areas covered by different satellites (43).
摘要翻译：基于卫星的通信系统（1）包括路由器系统（6），其经由卫星系统（4）从交换单元（3）接收与连接到交换单元（3）的通信终端（2）相关联的网络寻址信息，。通信终端（2）的网络寻址信息存储在分配给与通信终端（2）相关联的电话号码的路由器系统（6）中。为了使交换单元（7）经由卫星链路（40）将接收到的数据路由到通信终端（2），路由器系统（6）向交换单元（7）发送与通信终端相关联的网络寻址信息（2）连接到开关单元（3）。因此，数据可以灵活地路由在通信终端（2,2'）之间的基于卫星的通信系统（1）中，这些通信终端（2，2'）未被配置用于卫星通信，并且由移动用户使用，移动用户可以在不同卫星覆盖的区域中移动 43）。

4. 发明申请

WO2011127322A1 HIGH MANNOSE GLYCANS 审中-公开
标题翻译：高曼诺糖果
公开(公告)号：WO2011127322A1
公开(公告)日：2011-10-13
申请号：PCT/US2011/031637
申请日：2011-04-07
申请人： MOMENTA PHARMACEUTICALS, INC. , COLLINS, Brian, E. , DUFFNER, Jay , BOSQUES, Carlos, J. , BULIK, Dorota, A. , MYETTE, James
发明人： COLLINS, Brian, E. , DUFFNER, Jay , BOSQUES, Carlos, J. , BULIK, Dorota, A. , MYETTE, James
IPC分类号： C12Q1/00 , C12P21/06 , H01J49/00
CPC分类号： G01N33/5005 , C07K2319/30 , C12P21/005 , C12Q1/34 , C12Y302/01096 , C12Y302/01113 , G01N33/6803 , G01N33/6854 , G01N2333/924 , G01N2440/38 , H01J49/00
摘要： Methods and compositions related to high mannose glycans are described.
摘要翻译：描述了与高甘露糖聚糖相关的方法和组合物。

5. 发明申请

WO2011112494A1 METHODS OF FORMING WARM WHITE LIGHT EMITTING DEVICES HAVING HIGH COLOR RENDERING INDEX VALUES AND RELATED LIGHT EMITTING DEVICES 审中-公开
标题翻译：形成具有高色彩渲染指数值的白光发光装置的方法和相关的发光装置
公开(公告)号：WO2011112494A1
公开(公告)日：2011-09-15
申请号：PCT/US2011/027362
申请日：2011-03-07
申请人： CREE, INC. , COLLINS, Brian Thomas , CABALU, Jasper , DONOFRIO, Matthew , CANNON, Nathaniel O.
发明人： COLLINS, Brian Thomas , CABALU, Jasper , DONOFRIO, Matthew , CANNON, Nathaniel O.
IPC分类号： H01J1/62
CPC分类号： H01L33/504 , H01L25/0753 , H01L33/486 , H01L33/501 , H01L33/507 , H01L2224/48091 , H01L2224/8592 , H01L2933/0041 , H01L2924/00014
摘要： Methods of forming a light emitting device are provided in which a solid state lighting source is heated and a luminescent solution is applied to the heated solid state lighting source to form the light emitting device. The luminescent solution includes a first material that down-converts the radiation emitted by the solid state lighting source to radiation that has a peak wavelength in the green color range and that has a full width half maximum emission bandwidth that extends into the cyan color range, and at least one additional material that down-converts the radiation emitted by the solid state lighting source to radiation having a peak wavelength in another color range.
摘要翻译：提供形成发光器件的方法，其中加热固态光源并且将发光溶液施加到加热的固态光源以形成发光器件。发光溶液包括将由固态光源发射的辐射降频转换为具有绿色范围内的峰值波长并且具有延伸到青色范围的全宽度半最大发射带宽的辐射的第一材料，以及至少一种附加材料，其将由固态照明源发射的辐射下变频成具有另一颜色范围中的峰值波长的辐射。

6. 发明申请

WO2011021027A3 ANTENNAS WITH MULTIPLE FEED CIRCUITS 审中-公开
标题翻译：天线与多馈电路
公开(公告)号：WO2011021027A3
公开(公告)日：2011-05-26
申请号：PCT/GB2010051335
申请日：2010-08-12
申请人： ANTENOVA LTD , COLLINS BRIAN , HARPER MARC
发明人： COLLINS BRIAN , HARPER MARC
IPC分类号： H01Q1/24 , H01Q5/00 , H01Q7/00
CPC分类号： H01Q1/242 , H01Q7/00 , H01Q9/145
摘要： There is disclosed an antenna arrangement comprising an electrically conductive radiating element (20) having first and second ends, an electrically conductive ground plane or ground member (11), and an input terminal (27). The radiating element has a plurality of separate feed points (22, 23) at different locations between its first and second ends, and the input terminal is provided with a switch (26). Each feed point (22, 23) is electrically connected to the switch (26) by way of a separate electrical pathway, the switch (26) being configured to allow the separate feed points (22, 23) to be connected individually or in predetermined combinations to the input terminal (27) by selecting between a plurality of selectable contacts. At least one of the electrical pathways includes a capacitive circuit component (29) connected in series, and at least one other of the electrical pathways includes an inductive circuit component (28) connected in series. The antenna arrangement allows for a high degree of customization and improved matching, and enables good multi-band performance.
摘要翻译：公开了一种天线装置，其包括具有第一和第二端的导电辐射元件（20），导电接地平面或接地构件（11）和输入端子（27）。辐射元件在其第一和第二端之间的不同位置处具有多个单独的馈送点（22,23），并且输入端子设置有开关（26）。每个馈电点（22,23）通过单独的电路径与开关（26）电连接，开关（26）构造成允许单独的馈电点（22,23）被单独地或以预定的方式连接通过在多个可选择的触点之间进行选择来将输入端（27）组合到输入端。电路中的至少一个包括串联连接的电容电路部件（29），并且至少另一个电路径包括串联连接的电感电路部件（28）。天线布置允许高度的定制和改进的匹配，并且实现良好的多频带性能。

7. 发明申请

WO2010141855A1 METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS 审中-公开
标题翻译：调节GLYCOPROTEIN的纤维蛋白原的方法
公开(公告)号：WO2010141855A1
公开(公告)日：2010-12-09
申请号：PCT/US2010/037454
申请日：2010-06-04
申请人： MOMENTA PHARMACEUTICALS, INC. , COLLINS, Brian, Edward , THIRUNEELAKANTAPILLAI, Lakshmanan , BULIK, Dorota, A. , MILLEA, Kevin
发明人： COLLINS, Brian, Edward , THIRUNEELAKANTAPILLAI, Lakshmanan , BULIK, Dorota, A. , MILLEA, Kevin
IPC分类号： C12P21/04
CPC分类号： C12P21/005
摘要： The present invention provides methods and materials useful for monitoring and regulating the glycosylation of glycoproteins that are recombinantly produced from cells. In particular, methods are provided for monitoring and regulating levels of cellular indicators which affect the level of fucosylation produced by cells.
摘要翻译：本发明提供了用于监测和调节从细胞重组产生的糖蛋白糖基化的方法和材料。特别地，提供了用于监测和调节影响细胞产生的岩藻糖基化水平的细胞指标水平的方法。

8. 发明申请

WO2010138502A2 PRODUCTION OF GLYCOPROTEINS 审中-公开
标题翻译：生产糖蛋白
公开(公告)号：WO2010138502A2
公开(公告)日：2010-12-02
申请号：PCT/US2010036058
申请日：2010-05-25
申请人： MOMENTA PHARMACEUTICALS INC , COLLINS BRIAN , GUO TIFFANY , THIRUNEELAKANTAPILLAI LAKSHMANAN , MILLEA KEVIN , BULIK DOROTA
发明人： COLLINS BRIAN , GUO TIFFANY , THIRUNEELAKANTAPILLAI LAKSHMANAN , MILLEA KEVIN , BULIK DOROTA
IPC分类号： C12P21/06
CPC分类号： C12P21/005 , C12N9/14 , G01N2400/12 , G01N2400/38
摘要： The present invention provides methods and materials by which glycosylation of glycoproteins can be regulated. Methods include the monitoring and regulation of parameters such that a glycoprotein having a desired product quality is obtained.
摘要翻译：本发明提供可调节糖蛋白糖基化的方法和材料。方法包括监测和调节参数，使得获得具有所需产品质量的糖蛋白。

9. 发明申请

WO2010126592A1 LED PACKAGE WITH INCREASED FEATURE SIZES 审中-公开
标题翻译： LED包装具有增加的特征尺寸
公开(公告)号：WO2010126592A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/001255
申请日：2010-04-27
申请人： CREE, INC. , EMERSON, David , KELLER, Bernd , HUSSELL, Christopher , SALTER, Amber , COLLINS, Brian , BERGMANN, Michael , EDMOND, John , TARSA, Eric , ANDREWS, Peter
发明人： EMERSON, David , KELLER, Bernd , HUSSELL, Christopher , SALTER, Amber , COLLINS, Brian , BERGMANN, Michael , EDMOND, John , TARSA, Eric , ANDREWS, Peter
IPC分类号： H01L33/58 , H01L33/64 , H01L33/20
CPC分类号： H01L33/58 , H01L33/20 , H01L33/486 , H01L33/54 , H01L33/62 , H01L33/641 , H01L2224/48091 , H01L2924/01019 , H01L2924/01087 , H01L2924/00014
摘要： A light emitting diode (LED) package (30) having increased feature sizes for improved luminous flux and efficacy. A LED chip (34) is disposed on a submount (32) with a lens (70) that covers the LED chip. In some cases, the ratio of the width of the light LED chip to the width of said lens in a given direction is 0.5 or greater. Increased feature sizes allow the package to • emit light more efficiently. Some packages, include submounts having dimensions greater than 3.5 mm per 3.5 mm used in conjunction with larger LED chips. Materials having high thermal conductivities are used to fabricate the submounts, such as APN, providing the package with better thermal management.
摘要翻译：一种发光二极管（LED）封装（30），其具有增加的特征尺寸以改善光通量和功效。 LED芯片（34）设置在具有覆盖LED芯片的透镜（70）的底座（32）上。在一些情况下，光LED芯片的宽度与所述透镜在给定方向上的宽度的比率为0.5或更大。增加的特征尺寸可使包装更有效地发光。一些包装，包括尺寸大于3.5 mm / 3.5 mm的底座，与较大的LED芯片结合使用。使用具有高导热性的材料来制造诸如APN的底座，为封装提供更好的热管理。

10. 发明申请

WO2010070320A1 SEMICONDUCTOR DEVICE WITH INTEGRATED ANTENNA AND MANUFACTURING METHOD THEREFOR 审中-公开
标题翻译：具有集成天线的半导体器件及其制造方法
公开(公告)号：WO2010070320A1
公开(公告)日：2010-06-24
申请号：PCT/GB2009/051667
申请日：2009-12-08
申请人： ANTENOVA LIMITED , GAYNOR, Michael , COLLINS, Brian
发明人： GAYNOR, Michael , COLLINS, Brian
IPC分类号： H01L21/56 , H01L23/31 , H01L23/66 , H01Q1/22
CPC分类号： H01L23/66 , H01L21/565 , H01L23/3107 , H01L2223/6677 , H01L2924/0002 , H01L2924/09701 , H01L2924/19041 , H01Q1/2283 , H01L2924/00
摘要： There is disclosed a package comprising at least an integrated circuit embedded in an electrically non-conductive moulded material. The moulded material includes at least one moulded pattern on at least one surface thereof, and at least one electrically conductive track in the pattern. There is further provided at least one capacitive, inductive or galvanic component electrically connecting between at least two parts of the at least one electrically conductive track. The conductive track can be configured as an antenna, and the capacitive, inductive or galvanic component is used to adjust tuning and other characteristics of the antenna.
摘要翻译：公开了至少包括嵌入在非导电模制材料中的集成电路的封装。模制材料在其至少一个表面上包括至少一个模制图案，以及图案中的至少一个导电轨迹。还提供了电连接至少一个导电轨道的至少两个部分之间的至少一个电容，电感或电流元件。导电轨道可以配置为天线，电容，电感或电流分量用于调整天线的调谐和其他特性。

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