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1. 发明申请

WO03000373A9 SYSTEMS AND METHODS USING A SOLVENT FOR THE REMOVAL OF LIPIDS FROM FLUIDS 审中-公开
标题翻译：使用溶剂从流体中去除脂肪的系统和方法
公开(公告)号：WO03000373A9
公开(公告)日：2004-02-12
申请号：PCT/US0219643
申请日：2002-06-21
申请人： LIPID SCIENCES INC , BOMBERGER DAVID C , CHAVEZ BRYAN , GARCIA PABLO E , HEGWER ERIC , LOW THOMAS P , MALHOLTRA RIPUDAMAN , SHIMON JEFFREY J
发明人： BOMBERGER DAVID C , CHAVEZ BRYAN , GARCIA PABLO E , HEGWER ERIC , LOW THOMAS P , MALHOLTRA RIPUDAMAN , SHIMON JEFFREY J
IPC分类号： A61M1/16 , A61M1/18 , A61M1/34 , B01D11/04 , B01D61/14 , B01D61/36 , B01D11/00 , B01D61/00 , B01D63/02 , B01D63/04
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/50
摘要： Systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. A fluid is combined with at least one extraction solvent, which causes the lipids to separate from the fluid or from lipid-containing organisms. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to an acceptable concentration enabling the delipidated fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or stored for later use.
摘要翻译：用于从流体（例如血浆）或从含脂质生物体中除去脂质的系统和方法。流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。将分离的脂质从流体中除去。将萃取溶剂从流体中除去或至少降低到可接受的浓度，使得能够将脱脂流体施用于患者，而不会使患者经历不期望的后果。一旦流体被处理，流体可以被给予捐赠流体的患者给不同的患者，或者存储以供以后使用。

2. 发明申请

WO03000372A3 SYSTEMS AND METHODS USING MULTIPLE SOLVENTS FOR THE REMOVAL OF LIPIDS FROM FLUIDS 审中-公开
标题翻译：使用多种溶剂从流体中去除脂肪的系统和方法
公开(公告)号：WO03000372A3
公开(公告)日：2003-05-08
申请号：PCT/US0219726
申请日：2002-06-21
申请人： LIPID SCIENCES INC , BOMBERGER DAVID C , CHAVEZ BRYAN , GARCIA PABLO E , HEGWER ERIC , LOW THOMAS P , MALHOLTRA RIPUDAMAN , SHIMON JEFFREY J , VENTURELLI ANNE
发明人： BOMBERGER DAVID C , CHAVEZ BRYAN , GARCIA PABLO E , HEGWER ERIC , LOW THOMAS P , MALHOLTRA RIPUDAMAN , SHIMON JEFFREY J , VENTURELLI ANNE
IPC分类号： A61M1/34 , B01D61/36 , B01D33/21 , A61M1/14 , A61M1/36 , A61M37/00 , B01D11/00 , B01D11/04 , B01D15/00 , B01D61/00 , B01D61/02 , B01D61/24 , C02F1/26 , C02F1/44 , C02F9/00
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
摘要翻译：本发明涉及从流体或诸如血浆的流体中从含脂质生物体中除去脂质的系统和方法。这些系统将流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。将分离的脂质从流体中除去。将至少一种提取溶剂从流体中除去或者至少减少到使得能够向患者施用流体的浓度，而不会产生不期望的后果。一旦流体被处理，流体可以被施用给捐赠流体的患者或不同的患者进行治疗。

3. 发明申请

WO2003000372A2 SYSTEMS AND METHODS USING MULTIPLE SOLVENTS FOR THE REMOVAL OF LIPIDS FROM FLUIDS 审中-公开
标题翻译：用多种溶剂除去流体中脂质的系统和方法
公开(公告)号：WO2003000372A2
公开(公告)日：2003-01-03
申请号：PCT/US2002/019726
申请日：2002-06-21
申请人： LIPID SCIENCES, INC. , BOMBERGER, David C., , CHAVEZ, Bryan , GARCIA, Pablo E., , HEGWER, Eric , LOW, Thomas P., , MALHOLTRA, Ripudaman , SHIMON, Jeffrey J., , VENTURELLI, Anne
发明人： BOMBERGER, David C., , CHAVEZ, Bryan , GARCIA, Pablo E., , HEGWER, Eric , LOW, Thomas P., , MALHOLTRA, Ripudaman , SHIMON, Jeffrey J., , VENTURELLI, Anne
IPC分类号： B01D
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
摘要翻译：本发明涉及用于从流体（例如血浆）中从流体或含脂质生物中去除脂质的系统和方法。这些系统将流体与至少一种提取溶剂结合，其使得脂质与流体或含脂生物体分离。分离的脂质从流体中除去。将至少一种提取溶剂从流体中除去或者至少降低到能够将流体给予患者的浓度而没有不希望的后果。一旦流体已经被处理，流体可以被施用给捐献流体的患者或不同的患者以进行治疗。

4. 发明申请

WO2003000373A1 SYSTEMS AND METHODS USING A SOLVENT FOR THE REMOVAL OF LIPIDS FROM FLUIDS 审中-公开
标题翻译：使用溶剂从流体中去除脂肪的系统和方法
公开(公告)号：WO2003000373A1
公开(公告)日：2003-01-03
申请号：PCT/US2002/019643
申请日：2002-06-21
申请人： LIPID SCIENCES, INC. , BOMBERGER, David C., , CHAVEZ, Bryan , GARCIA, Pablo, E. , HEGWER, Eric , LOW, Thomas, p. , MALHOLTRA, Ripudaman , SHIMON, Jeffrey, j.
发明人： BOMBERGER, David C., , CHAVEZ, Bryan , GARCIA, Pablo, E. , HEGWER, Eric , LOW, Thomas, p. , MALHOLTRA, Ripudaman , SHIMON, Jeffrey, j.
IPC分类号： B01D11/00
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/50
摘要： Systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. A fluid is combined with at least one extraction solvent, which causes the lipids to separate from the fluid or from lipid-containing organisms. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to an acceptable concentration enabling the delipidated fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or stored for later use.
摘要翻译：用于从流体（例如血浆）或从含脂质生物体中除去脂质的系统和方法。流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。将分离的脂质从流体中除去。将萃取溶剂从流体中除去或至少降低到可接受的浓度，使得能够将脱脂流体施用于患者，而不会使患者经历不期望的后果。一旦流体被处理，流体可以被给予捐赠流体的患者给不同的患者，或者存储以供以后使用。

5. 发明申请

WO1997034660A1 METHOD FOR HOT AND SUPERCRITICAL WATER OXIDATION OF MATERIAL USING SPECIFIC REACTANTS 审中-公开
标题翻译：使用特定反应物的材料的热超临界水氧化方法
公开(公告)号：WO1997034660A1
公开(公告)日：1997-09-25
申请号：PCT/US1997004443
申请日：1997-03-19
申请人： SRI INTERNATIONAL , ROSS, David, S. , JAYAWEERA, Indira , BOMBERGER, David, C. , LEIF, Roald, N.
发明人： SRI INTERNATIONAL
IPC分类号： A62D03/00
CPC分类号： A62D3/20 , A62D2101/22 , A62D2101/28 , C02F1/722 , C02F11/086 , C02F2101/36 , Y10S210/908 , Y10S210/909 , Y10S210/915
摘要： This invention relates to a process for the decomposition of material selected from halogenated organic compounds, to compounds which are environmentally acceptable, or are amenable to further degradation by conventional disposal systems to produce environmentally acceptable products, which process comprises: (a) conveying an aqueous solution or an aqueous slurry of material into a reaction zone capable of withstanding the temperatures and pressures of decomposition of the material; (b) contacting the material in the reaction zone with aqueous sodium carbonate as a reactant in an amount effective to decompose the material under hydrothermal oxidation conditions of between about 300 and 600 DEG C and a pressure of between about 10 and 400 atmospheres for between 0.01 and 120 min wherein the specific reactant, a carbonate such as sodium carbonate, at the reaction conditions is present at about 10 % or less as a water-soluble salt as compared to the solubility of the salt at ambient conditions wherein the specific reactant is essentially present as a solid and the oxidation occurs under heterogeneous conditions, wherein the process occurs in the presence of a gaseous oxidant wherein said oxidant is present in an amount of between about 0.01 and 50 % by weight of the material; (c) producing about 99 % or greater of the decomposition of the material, or 99 % or greater conversion of the material to compounds which are environmentally acceptable or to compounds which are amendable to further degradation; and (d) optionally degrading further the compounds produced in step (c) by reaction to environmentally acceptable products. Preferably, the specific reactant is sodium carbonate and the oxidant is oxygen or air. Preferably, the halogenated organic compound is selected from polychlorobiphenyl, polybromobiphenyl mono-chlorobenzodioxin or poly-chlorobenzodioxin compounds.
摘要翻译：本发明涉及一种将选自卤代有机化合物的材料分解成环境可接受的化合物或通过常规处理系统进一步降解以生产环境可接受的产品的方法，该方法包括：（a）输送水性溶液或材料的水性浆料进入能够承受材料分解的温度和压力的反应区; （b）使反应区中的材料与碳酸钠水溶液作为反应物接触，其量可以有效地在约300-600℃的水热氧化条件下分解该材料，在约10-400个大气压之间压力为0.01 和120分钟，其中在反应条件下的特定反应物碳酸酯如碳酸钠在水溶性盐中的存在量为约10％或更少，与盐在环境条件下的溶解度相比，其中特定反应物基本上是作为固体存在并且氧化发生在非均相条件下，其中该方法在气态氧化剂存在下进行，其中所述氧化剂的存在量为所述材料重量的约0.01％至50％; （c）产生约99％或更多的材料分解，或99％或更多的材料转化为环境可接受的化合物或可修饰为进一步降解的化合物; 和（d）通过与环境可接受的产物反应，任选进一步降解步骤（c）中产生的化合物。优选地，特定反应物是碳酸钠，氧化剂是氧气或空气。优选地，卤代有机化合物选自聚氯联苯，聚溴联苯一氯代二氯苯或聚氯苯并二恶英化合物。

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