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1. 发明申请

WO2004047914A1 PELVIC DISORDER TREATMENT DEVICE 审中-公开
标题翻译：病毒治疗装置
公开(公告)号：WO2004047914A1
公开(公告)日：2004-06-10
申请号：PCT/IL2002/000963
申请日：2002-11-28
申请人： BIOCONTROL MEDICAL LTD. , COHEN, Ehud , GROSS, Yossi , NISSENKORN, Israel
发明人： COHEN, Ehud , GROSS, Yossi , NISSENKORN, Israel
IPC分类号： A61N1/08
CPC分类号： A61N1/36007 , A61B5/0031 , A61B5/0215 , A61B5/0488 , A61B5/145 , A61B5/202 , A61B5/204 , A61B5/205 , A61B5/227 , A61B5/4047 , A61B5/6874 , A61B8/12 , A61B8/4472 , A61B2560/0209 , A61B2562/0219
摘要： A device (20) for treating a medical condition is provided, and a surgical procedure for implanting the device is disclosed. The device (20) includes a sensor (44), which is adapted to generate a signal responsive to a state of a patient, and at least one electrode (27), which is adapted to be coupled to a pelvic site of the patient. A control unit (22) is adapted to receive the signal, to analyze the signal so as to distinguish between an imminent stress incontinence event and an imminent urge event, and, responsive to analyzing the signal, to apply an electrical waveform to the at least one electrode (27). In various configurations, the device (20) may be used alternatively or additionally to treat fecal incontinence, interstitial cystitis, chronic pelvic pain, or urine retention.
摘要翻译：提供了用于治疗医疗状况的装置（20），并且公开了用于植入该装置的外科手术。所述装置（20）包括传感器（44），所述传感器适于产生响应于患者状态的信号，以及至少一个电极（27），所述至少一个电极适于联接到患者的骨盆部位。控制单元（22）适于接收信号，分析信号以便区分即将发生的压力性尿失禁事件和迫在眉睫事件，并且响应于分析信号，将电波形施加到至少一个电极（27）。在各种构造中，装置（20）可以替代地或另外地用于治疗大便失禁，间质性膀胱炎，慢性盆腔疼痛或尿滞留。

2. 发明申请

WO2004110549A2 APPLICATIONS OF VAGAL STIMULATION 审中-公开
标题翻译： VAGAL刺激的应用
公开(公告)号：WO2004110549A2
公开(公告)日：2004-12-23
申请号：PCT/IL2004/000495
申请日：2004-06-10
申请人： BIOCONTROL MEDICAL LTD. , BEN EZRA, Omry , COHEN, Ehud , BEN DAVID, Tamir , DABBY, Ron
发明人： BEN EZRA, Omry , COHEN, Ehud , BEN DAVID, Tamir , DABBY, Ron
IPC分类号： A61N
CPC分类号： A61N1/36114 , A61N1/36117 , A61N1/3621 , A61N1/395 , A61N1/3962
摘要： A method is provided for treating a subject (30) suffering from atrial fibrillation (AF), including administering a drug for treating the AF to the subject (30); applying a current to a site of the subject selected from the list consisting of: a vagus nerve (24) of the subject (30), an epicardial fat pad of the subject (30), a pulmonary vein of the subject (30), a carotid artery of the subject (30), a carotid sinus of the subject (30), a vena cava vein of the subject (30), and an internal jugular vein of the subject (30); and configuring the current to increase vagal tone of the subject (30), so as to treat the AF. For some applications, configuring the current includes configuring the current so as to enhance an efficacy of the drug.
摘要翻译：提供一种治疗患有房颤（AF）的受试者（30）的方法，包括给予对象（30）治疗AF的药物; 对从所述受试者（30）的迷走神经（24），所述受试者（30）的心外膜脂肪垫，所述受试者（30）的肺静脉构成的列表中应用电流，受试者（30）的颈动脉，受试者（30）的颈动脉窦，受试者（30）的腔静脉和受试者（30）的颈内静脉; 以及配置电流以增加受试者（30）的迷走神经张力，以便治疗房颤。对于一些应用，配置电流包括配置电流以提高药物的功效。

3. 发明申请

WO2004028624A3 NERVE STIMULATION FOR TREATING SPASTICITY, TREMOR, MUSCLE WEAKNESS, AND OTHER MOTOR DISORDERS 审中-公开
标题翻译：神经刺激治疗弹性，有力，肌肉无力和其他运动障碍
公开(公告)号：WO2004028624A3
公开(公告)日：2004-04-29
申请号：PCT/IL0300765
申请日：2003-09-24
申请人： BIOCONTROL MEDICAL LTD , AYAL SHAI , COHEN EHUD , DABBY RON
发明人： AYAL SHAI , COHEN EHUD , DABBY RON
IPC分类号： A61N1/18 , A61N1/34 , A61N1/36 , A61N1/372
CPC分类号： A61N1/36021 , A61N1/36003 , A61N1/36007 , A61N1/36067 , A61N1/36071 , A61N1/37205
摘要： A method for treating spasticity of a subject is provided, including driving a current into a nerve of the subject that includes one or more sensory fibers, and configuring the current so as to inhibit propagation of action potentials in one or more of the sensory fibers, so as to treat the spasticity. In a preferred embodiment, the sensory fibers include one or more Ia sensory fibers, and configuring the current includes configuring the current so as to inhibit propagation of the action potentials in at least one of the Ia sensory fibers.
摘要翻译：提供了用于治疗受试者痉挛状态的方法，包括将电流驱入包括一种或多种感觉纤维的受试者的神经中，并且配置电流以抑制动作电位在一种或多种感觉纤维中的传播，以治疗痉挛。在优选实施方案中，感觉纤维包括一种或多种Ia感觉纤维，并且配置电流包括配置电流以抑制动作电位在至少一种Ia感觉纤维中的传播。

4. 发明申请

WO2003094693A3 LOW POWER CONSUMPTION IMPLANTABLE PRESSURE SENSOR 审中-公开
公开(公告)号：WO2003094693A3
公开(公告)日：2003-11-20
申请号：PCT/IL2002/000962
申请日：2002-11-28
申请人： BIOCONTROL MEDICAL LTD. , COHEN, Ehud , VAINGAST, Shai, Moshe , BETSER, Nir , GROSS, Yossi
发明人： COHEN, Ehud , VAINGAST, Shai, Moshe , BETSER, Nir , GROSS, Yossi
IPC分类号： A61B5/02
摘要： Pressure-measuring apparatus (100) is provided, including a battery (118) and a pressure transducer (114). The pressure transducer (114) is adapted to be placed in a patient, and has a characteristic mechanical response bandwidth f, and a corresponding mechanical response period p equal to 1/f. A control unit (102) is adapted to actuate the battery (118) to drive current through the pressure transducer (114) for a current-driving time period less than 0.5 p, and to sense an electrical characteristic of the pressure transducer (114) during the current-driving time period.

5. 发明申请

WO2002087683A3 ACTUATION AND CONTROL OF LIMBS THROUGH MOTOR NERVE STIMULATION 审中-公开
公开(公告)号：WO2002087683A3
公开(公告)日：2002-11-07
申请号：PCT/IL2002/000331
申请日：2002-04-26
申请人： BIOCONTROL MEDICAL LTD. , COHEN, Ehud , GROSS, Yossi
发明人： COHEN, Ehud , GROSS, Yossi
IPC分类号： A61N1/18
摘要： Apparatus (20) for actuating a skeletal muscle of a patient is provided. The apparatus typically includes a plurality of electrodes (24), which are adapted to be placed in a vicinity of a motor nerve that innervates the skeletal muscle. A control unit (22), is preferably adapted to drive a current between two or more of the plurality of electrodes, and to configure the current such that a first subset of axons in the nerve is excited by the current and such that a second subset of axons in the nerve is not excited by the current.

6. 发明申请

WO2008041233A2 TECHNIQUES FOR GALL BLADDER STIMULATION 审中-公开
标题翻译： GALL BLADDER刺激技术
公开(公告)号：WO2008041233A2
公开(公告)日：2008-04-10
申请号：PCT/IL2007/001204
申请日：2007-10-07
申请人： BIOCONTROL MEDICAL LTD.
发明人： BEN-EZRA, Omry , BEN-DAVID, Tamir , COHEN, Ehud
IPC分类号： A61B17/24
CPC分类号： A61N1/36007
摘要： Apparatus (10) for treating a patient (24) is provided, including an electrode device (20), which is configured to be placed in a vicinity of at least one gall bladder site of the patient (24) selected from the group consisting of: a gall bladder (22), a neck (32) of the gall bladder, a cystic duct (34), a hepatic duct, a common hepatic duct, a bile duct, a common bile duct, sensory fibers of the gall bladder, and a hepatic port. The apparatus (10) further includes a control unit (30), which is configured to drive the electrode device (20) to apply a current to the site, and to configure the current to induce weight loss of the patient (24). Other embodiments are also described.
摘要翻译：提供了一种用于治疗患者（24）的装置（10），包括电极装置（20），其被配置为放置在患者（24）的至少一个胆囊部位附近，所述胆囊部位选自：胆囊（22），胆囊的颈部（32），胆囊管（34），肝管，肝胆管，胆管，胆总管，胆囊感觉纤维，和肝端口。所述装置（10）还包括控制单元（30），其被配置为驱动所述电极装置（20）向所述现场施加电流，并且配置所述电流以引起所述患者（24）的体重减轻。还描述了其它实施例。

7. 发明申请

WO2004110549A3 APPLICATIONS OF VAGAL STIMULATION 审中-公开
标题翻译： VAGAL刺激的应用
公开(公告)号：WO2004110549A3
公开(公告)日：2005-03-31
申请号：PCT/IL2004000495
申请日：2004-06-10
申请人： BIOCONTROL MEDICAL LTD , BEN EZRA OMRY , COHEN EHUD , BEN DAVID TAMIR , DABBY RON
发明人： BEN EZRA OMRY , COHEN EHUD , BEN DAVID TAMIR , DABBY RON
IPC分类号： A61N20060101 , A61N1/18 , A61N1/36 , A61N1/362 , A61N1/365 , A61N1/39
CPC分类号： A61N1/36114 , A61N1/36117 , A61N1/3621 , A61N1/395 , A61N1/3962
摘要： A method is provided for treating a subject (30) suffering from atrial fibrillation (AF), including administering a drug for treating the AF to the subject (30); applying a current to a site of the subject selected from the list consisting of: a vagus nerve (24) of the subject (30), an epicardial fat pad of the subject (30), a pulmonary vein of the subject (30), a carotid artery of the subject (30), a carotid sinus of the subject (30), a vena cava vein of the subject (30), and an internal jugular vein of the subject (30); and configuring the current to increase vagal tone of the subject (30), so as to treat the AF. For some applications, configuring the current includes configuring the current so as to enhance an efficacy of the drug.
摘要翻译：提供一种治疗患有房颤（AF）的受试者（30）的方法，包括给予对象（30）治疗AF的药物; 对从所述受试者（30）的迷走神经（24），所述受试者（30）的心外膜脂肪垫，所述受试者（30）的肺静脉构成的列表中应用电流，受试者（30）的颈动脉，受试者（30）的颈动脉窦，受试者（30）的腔静脉和受试者（30）的颈内静脉; 以及配置电流以增加受试者（30）的迷走神经张力，以便治疗房颤。对于一些应用，配置电流包括配置电流以提高药物的功效。

8. 发明申请

WO2003094693A2 LOW POWER CONSUMPTION IMPLANTABLE PRESSURE SENSOR 审中-公开
标题翻译：低功耗可压式压力传感器
公开(公告)号：WO2003094693A2
公开(公告)日：2003-11-20
申请号：PCT/IL2002/000962
申请日：2002-11-28
申请人： BIOCONTROL MEDICAL LTD. , COHEN, Ehud , VAINGAST, Shai, Moshe , BETSER, Nir , GROSS, Yossi
发明人： COHEN, Ehud , VAINGAST, Shai, Moshe , BETSER, Nir , GROSS, Yossi
IPC分类号： A61B
CPC分类号： A61B5/0215 , A61B5/0031 , A61B5/145 , A61B5/205 , A61B5/6874
摘要： Pressure-measuring apparatus (100) is provided, including a battery (118) and a pressure transducer (114). The pressure transducer (114) is adapted to be placed in a patient, and has a characteristic mechanical response bandwidth f, and a corresponding mechanical response period p equal to 1/f. A control unit (102) is adapted to actuate the battery (118) to drive current through the pressure transducer (114) for a current-driving time period less than 0.5 p, and to sense an electrical characteristic of the pressure transducer (114) during the current-driving time period.
摘要翻译：提供了包括电池（118）和压力传感器（114）的压力测量装置（100）。压力换能器（114）适于放置在患者身上，并且具有特征性机械响应带宽f和对应于1 / f的机械响应周期p。控制单元（102）适于致动电池（118）以驱动通过压力传感器（114）的电流达到小于0.5p的电流驱动时间段，并且感测压力传感器（114）的电特性，在当前行车期间。

9. 发明申请

WO2002087683A2 ACTUATION AND CONTROL OF LIMBS THROUGH MOTOR NERVE STIMULATION 审中-公开
标题翻译：通过电动神经刺激实施和控制
公开(公告)号：WO2002087683A2
公开(公告)日：2002-11-07
申请号：PCT/IL2002/000331
申请日：2002-04-26
申请人： BIOCONTROL MEDICAL LTD. , COHEN, Ehud , GROSS, Yossi
发明人： COHEN, Ehud , GROSS, Yossi
IPC分类号： A61N
CPC分类号： A61N1/36003 , A61N1/37205
摘要： Apparatus (20) for actuating a skeletal muscle of a patient is provided. The apparatus typically includes a plurality of electrodes (24), which are adapted to be placed in a vicinity of a motor nerve that innervates the skeletal muscle. A control unit (22), is preferably adapted to drive a current between two or more of the plurality of electrodes, and to configure the current such that a first subset of axons in the nerve is excited by the current and such that a second subset of axons in the nerve is not excited by the current.
摘要翻译：提供用于致动患者骨骼肌的装置（20）。该装置通常包括多个电极（24），其适于放置在支配骨骼肌的运动神经附近。控制单元（22）优选地适于驱动多个电极中的两个或更多个之间的电流，并且配置电流，使得神经中的轴突的第一子集被电流激发，并且使得第二子集神经中的轴突不受现在的兴奋。

10. 发明申请

WO2008041233A3 TECHNIQUES FOR GALL BLADDER STIMULATION 审中-公开
标题翻译： GALL BLADDER刺激技术
公开(公告)号：WO2008041233A3
公开(公告)日：2016-06-09
申请号：PCT/IL2007001204
申请日：2007-10-07
申请人： BIOCONTROL MEDICAL LTD
发明人： BEN-EZRA OMRY , BEN-DAVID TAMIR , COHEN EHUD
IPC分类号： A61N1/05
CPC分类号： A61N1/36007
摘要： Apparatus (10) for treating a patient (24) is provided, including an electrode device (20), which is configured to be placed in a vicinity of at least one gall bladder site of the patient (24) selected from the group consisting of: a gall bladder (22), a neck (32) of the gall bladder, a cystic duct (34), a hepatic duct, a common hepatic duct, a bile duct, a common bile duct, sensory fibers of the gall bladder, and a hepatic port. The apparatus (10) further includes a control unit (30), which is configured to drive the electrode device (20) to apply a current to the site, and to configure the current to induce weight loss of the patient (24). Other embodiments are also described.
摘要翻译：提供了一种用于治疗患者（24）的装置（10），其包括电极装置（20），其被配置为放置在患者（24）的至少一个胆囊部位附近，所述胆囊部位选自：胆囊（22），胆囊的颈部（32），胆囊管（34），肝管，肝胆管，胆管，胆总管，胆囊感觉纤维，和肝端口。所述装置（10）还包括控制单元（30），其被配置为驱动所述电极装置（20）向所述现场施加电流，并且配置所述电流以引起所述患者（24）的体重减轻。还描述了其它实施例。

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