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1. 发明申请

WO2018033920A1 DRUG DELIVERY CATHETER AND METHOD OF USE THEREOF 审中-公开
标题翻译：药物递送导管及其使用方法
公开(公告)号：WO2018033920A1
公开(公告)日：2018-02-22
申请号：PCT/IL2017/050911
申请日：2017-08-17
申请人： ANGIOSLIDE LTD.
发明人： VICKOS, Eran , AVITOV, Lihu , FITZGERALD, Peter J. , HARARI, Eran
IPC分类号： A61M25/10
摘要： A drug delivery catheter includes a shaft, an inflatable inner balloon attached to the shaft. The inflatable balloon has an outer surface coated with a drug or a composition including a drug. The catheter also includes a perforated outer balloon. The perforated outer balloon surrounds the inflatable inner balloon. The perforated balloon has multiple perforations therein. A method of delivering a drug to a treated site using the catheter includes inserting the catheter into a body cavity to dispose the perforated outer balloon in a site to be treated and inflating the inflatable balloon to treat the site and to deliver the drug to at least some regions of the treated site through the multiple perforations. The body cavity may be a blood vessel or any other body cavity.
摘要翻译：药物输送导管包括轴，连接至轴的可膨胀的内部气囊。可膨胀气囊具有涂有药物或包含药物的组合物的外表面。导管还包括穿孔的外部气囊。穿孔的外部气囊围绕可充气的内部气囊。多孔气球在其中具有多个穿孔。使用导管将药物递送至治疗部位的方法包括将导管插入体腔中以将穿孔的外部气囊放置在待治疗的部位中并且使可膨胀的气囊膨胀以治疗该部位并且将药物递送至少治疗部位的一些区域通过多个穿孔。体腔可以是血管或任何其他体腔。

2. 发明申请

WO2010079494A1 BALLOON AND CATHETER SYSTEM AND METHODS FOR MAKING AND USE THEREOF 审中-公开
标题翻译：气体和导管系统及其制造和使用的方法
公开(公告)号：WO2010079494A1
公开(公告)日：2010-07-15
申请号：PCT/IL2010/000025
申请日：2010-01-11
申请人： ANGIOSLIDE LTD. , HARARI, Eran , BESSER, Doron
发明人： HARARI, Eran , BESSER, Doron
IPC分类号： A61M29/00 , A61M31/00 , A61M37/00
CPC分类号： A61M25/1002 , A61M25/1006 , A61M25/10181 , A61M25/10184 , A61M25/1027 , A61M25/1029 , A61M2025/0004 , A61M2025/1068 , A61M2025/1084
摘要： A catheter includes an outer conduit and an inner conduit having at least one movable part movably disposed within the outer conduit. An inflatable balloon has a proximal margin sealingly attached to the distal outer conduit's distal end, and a distal margin sealingly attached to the distal end of the movable part. The balloon includes a proximal portion, a middle portion and a distal portion. The distal balloon portion or the proximal balloon portion is a reinforced portion having at least some reinforced part for increasing the force required to initiate collapse of the reinforced portion. The remaining portion of the balloon is not reinforced. The catheter may also include a moving mechanism for axially moving the movable part of the inner conduit within the outer conduit, a fluid port for the introduction of an expansion fluid and a pressure regulating mechanism for reducing pressure changes within the catheter.
摘要翻译：导管包括外部管道和内部管道，其具有可移动地设置在外部管道内的至少一个可移动部件。可膨胀气囊具有密封地附接到远端外导管的远端的近侧边缘，以及密封地附接到可移动部件的远端的远侧边缘。气囊包括近端部分，中部部分和远端部分。远侧球囊部分或近端球囊部分是具有至少一些加强部分的加强部分，用于增加开始加强部分的塌陷所需的力。气球的剩余部分没有加强。导管还可以包括用于在外导管内轴向移动内管道的可移动部分的移动机构，用于引入膨胀流体的流体端口和用于减小导管内的压力变化的压力调节机构。

3. 发明申请

WO2007042935A3 BALLOON CATHETER 审中-公开
标题翻译：气球导管
公开(公告)号：WO2007042935A3
公开(公告)日：2009-04-16
申请号：PCT/IB2006002955
申请日：2006-10-13
申请人： ANGIOSLIDE LTD , HIRSZOWICZ ERAN , DUBI SHAY
发明人： HIRSZOWICZ ERAN , DUBI SHAY
IPC分类号： A61F2/958 , A61M29/00 , A61M31/00 , A61M37/00
CPC分类号： A61M25/1006 , A61M25/0119 , A61M25/104 , A61M2025/0183 , A61M2025/1015 , A61M2025/1068 , A61M2025/109
摘要： The present invention is primarily directed to a rapid exchange catheter that permits axial movement of an inner conduit within an outer conduit comprising: an outer conduit; an inner conduit, suitable for total or partial passage over a guide wire, wherein said inner conduit is movably disposed within the lumen of said outer conduit, wherein the proximal end of said inner conduit is angled such that it pierces the wall of said outer conduit; means for permitting axial movement of said inner conduit within said outer conduit, such that said movement is not hindered by the passage of the angled proximal part of the inner conduit through said outer conduit; and means, situated at the proximal end of the outer conduit, for causing axial pushing-pulling movements of said inner conduit.
摘要翻译：本发明主要涉及一种快速交换导管，其允许内导管在外导管内的轴向移动，包括：外导管; 内导管，其适于在导线上全部或部分通过，其中所述内导管可移动地设置在所述外导管的内腔中，其中所述内导管的近端成角度，使得其穿透所述外导管的壁 ; 用于允许所述内部管道在所述外部管道内轴向移动的装置，使得所述运动不受所述内部导管的成角度的近端部分通过所述外部导管的阻碍; 以及位于所述外部导管的近端处的用于引起所述内部导管的轴向推动拉动的装置。

4. 发明申请

WO2005102184A1 CATHETER 审中-公开
标题翻译：导管
公开(公告)号：WO2005102184A1
公开(公告)日：2005-11-03
申请号：PCT/IL2005/000420
申请日：2005-04-21
申请人： ANGIOSLIDE LTD. , HIRSZOWICZ, Eran , HIRSZOWICZ, Orit , TURGEMAN, Yoav , MAIRON, Omri
发明人： HIRSZOWICZ, Eran , HIRSZOWICZ, Orit , TURGEMAN, Yoav , MAIRON, Omri
IPC分类号： A61B17/22
CPC分类号： A61B17/22032 , A61B17/221 , A61B2017/22034 , A61B2017/22035 , A61B2017/3435 , A61F2/958 , A61F2002/9528 , A61F2002/9586 , A61M25/10 , A61M2025/006 , A61M2025/1081 , A61M2025/109
摘要： A system comprising a catheter (12) having an expandable element (18), which when expanded, has an annular shape surrounding a passageway. The expandable element in the expanded state is rollable along at least a portion of the shaft of the catheter without slipping. The system may be used for delivering an object to a site in the body, retrieving an object from a body, removing debris and/or other particulate matter from a blood vessel, and distending and/or expanding a pathologically-involved region of a blood vessel wall.
摘要翻译：一种包括具有可膨胀元件（18）的导管（12）的系统，其在膨胀时具有围绕通道的环形形状。处于膨胀状态的可膨胀元件可沿导管的轴的至少一部分滚动，而不会滑动。该系统可以用于将物体递送到身体中的部位，从身体检索物体，从血管中去除碎屑和/或其它颗粒物质，以及膨胀和/或扩张病理学上涉及的血液区域血管壁。

5. 发明申请

WO2014087395A1 BALLOON CATHETER AND METHODS OF USE THEREOF 审中-公开
标题翻译：气球导管及其使用方法
公开(公告)号：WO2014087395A1
公开(公告)日：2014-06-12
申请号：PCT/IL2013/000089
申请日：2013-12-04
申请人： ANGIOSLIDE LTD , FEIG, Roy , MEISTER, Gal , BARASH, Alex , BERNSTEIN, Gil
发明人： FEIG, Roy , MEISTER, Gal , BARASH, Alex , BERNSTEIN, Gil
IPC分类号： A61M25/00 , A61M25/10
CPC分类号： A61M25/104 , A61B17/22031 , A61B17/22032 , A61B17/221 , A61B2017/22035 , A61B2017/22038 , A61B2017/22051 , A61B2017/22052 , A61B2017/22054 , A61B2017/22061 , A61B2017/22065 , A61B2017/22079 , A61B2017/2215 , A61F2/958 , A61F2002/9583 , A61M1/0009 , A61M1/0011 , A61M1/0039 , A61M1/0045 , A61M1/0066 , A61M1/0072 , A61M25/0074 , A61M25/0082 , A61M25/1006 , A61M25/1011 , A61M2025/0004 , A61M2025/0024 , A61M2025/0039 , A61M2025/0183 , A61M2025/1013 , A61M2025/1015 , A61M2025/105 , A61M2025/1052 , A61M2025/1081 , A61M2025/1086 , A61M2025/109 , A61M2025/1093 , A61M2202/0007 , A61M2202/0014 , A61M2205/32
摘要： A balloon catheter including a shaft and an inflatable balloon attached to the shaft, the catheter includes an open sleeve having a proximal end sealingly attached to the catheter shaft and an open distal end. The sleeve surrounds at least part of the balloon. The sleeve and the balloon are arranged such that inflating the balloon expands the sleeve into an expanded state and deflating the balloon when the sleeve is in the expanded state forms an open cavity between the sleeve and the deflated balloon and creates suction to capture and retain debris within the cavity.
摘要翻译：包括轴和可附接到所述轴的可充气气囊的球囊导管，所述导管包括开口套筒，所述开口套筒具有密封地附接到所述导管轴的近端和敞开的远端。套筒围绕气球的至少一部分。套筒和气囊被布置成使得气囊膨胀使套管膨胀成膨胀状态，并且当套筒处于膨胀状态时使气囊膨胀在套管和放气气囊之间形成开放空腔，并产生抽吸以捕获并保持碎屑在腔内。

6. 发明申请

WO2007042935A2 BALLOON CATHETER 审中-公开
标题翻译：气球导管
公开(公告)号：WO2007042935A2
公开(公告)日：2007-04-19
申请号：PCT/IB2006/002955
申请日：2006-10-13
申请人： AngioSlide Ltd. , HIRSZOWICZ, Eran , DUBI, Shay
发明人： HIRSZOWICZ, Eran , DUBI, Shay
IPC分类号： A61M25/14
CPC分类号： A61M25/1006 , A61M25/0119 , A61M25/104 , A61M2025/0183 , A61M2025/1015 , A61M2025/1068 , A61M2025/109
摘要： The present invention is primarily directed to a rapid exchange catheter that permits axial movement of an inner conduit within an outer conduit comprising: • an outer conduit; • an inner conduit, suitable for total or partial passage over a guide wire, wherein said inner conduit is movably disposed within the lumen of said outer conduit, wherein the proximal end of said inner conduit is angled such that it pierces the wall of said outer conduit; • means for permitting axial movement of said inner conduit within said outer conduit, such that said movement is not hindered by the passage of the angled proximal part of the inner conduit through said outer conduit; and • means, situated at the proximal end of the outer conduit, for causing axial pushing-pulling movements of said inner conduit.
摘要翻译：本发明主要涉及一种快速交换导管，其允许内导管在外导管内的轴向移动，包括：外导管; 内导管，其适于在导线上全部或部分通过，其中所述内导管可移动地设置在所述外导管的内腔中，其中所述内导管的近端成角度，使得其穿透所述外导管的壁 ; 用于允许所述内部管道在所述外部管道内轴向移动的装置，使得所述运动不受所述内部导管的成角度的近端部分通过所述外部导管的阻碍; 以及位于所述外部导管的近端处的用于引起所述内部导管的轴向推动拉动的装置。

7. 发明申请

WO2007004221A1 BALLOON CATHETER 审中-公开
标题翻译：气球导管
公开(公告)号：WO2007004221A1
公开(公告)日：2007-01-11
申请号：PCT/IL2006/000770
申请日：2006-07-03
申请人： ANGIOSLIDE LTD. , HIRSZOWICZ, Eran , DUBI, Shay
发明人： HIRSZOWICZ, Eran , DUBI, Shay
IPC分类号： A61M25/10 , A61B17/22
CPC分类号： A61B17/22032 , A61M25/0119 , A61M25/1006
摘要： The present invention is primarily directed to a balloon catheter system comprising outer and inner conduits, wherein said inner conduit is capable of being moved along its longitudinal axis in relation to said outer conduit. An angioplastic balloon is connected between the distal portions of the two conduits, such that the distal and/or proximal end portions of said balloon is/are capable of intussusception upon proximal movement of said inner conduit in relation to said outer conduit. Finally, the system further comprises means for the introduction of an expansion fluid into the annular space formed between the inner surface of the outer conduit and the outer surface of the inner conduit as well as means for preventing pressure changes within said annular space upon axial movement of said inner conduit in relation to said outer conduit.
摘要翻译：本发明主要涉及一种包括外导管和内导管的球囊导管系统，其中所述内导管能够相对于所述外导管沿其纵向轴线移动。血管生成气囊连接在两个管道的远端部分之间，使得所述气囊的远端和/或近端部分能够相对于所述外部管道在所述内部导管的近端移动时能够套叠。最后，该系统还包括用于将膨胀流体引入形成在外管道的内表面和内管道的外表面之间的环形空间的装置，以及用于在轴向移动时防止所述环形空间内的压力变化的装置的所述内导管相对于所述外导管。

8. 发明申请

WO2016199117A1 IMPROVED BALLOON CATHETER AND METHOD OF USE 审中-公开
标题翻译：改进的气泡导管及其使用方法
公开(公告)号：WO2016199117A1
公开(公告)日：2016-12-15
申请号：PCT/IL2015/050582
申请日：2015-06-09
申请人： ANGIOSLIDE LTD
发明人： HARARI, Eran , MEISTER, Gal , BERNSTEIN, Gil , BARASH, Alexander , FEIG, Roy
IPC分类号： A61M25/00
CPC分类号： A61B17/22 , A61B17/320725 , A61B2017/22034 , A61B2017/22051 , A61B2017/22079 , A61B2017/22082 , A61B2017/22084 , A61B2017/22085 , A61B2017/2215 , A61F2/958 , A61M25/0032 , A61M2025/0037 , A61M2025/105 , A61M2025/1081
摘要： A balloon catheter comprising an inflatable balloon at a distal end of a lumen for allowing passage of a fluid to said inflatable balloon for inflating said balloon, the balloon catheter further comprising a bell shaped sleeve covering the balloon of the balloon catheter such that inflation of said balloon causes said sleeve to dilate, whereas subsequent deflation of said balloon by extraction of the fluid, causes the balloon to separate from the dilated bell shaped sleeve, and a bell shaped sleeve having a circumferential wall for covering a balloon with a circumferential wall of a balloon catheter that is inflatable by a lumen; the bell shaped sleeve having a closed proximal end closely surrounding the lumen, and an open distal end, such that inflation of the balloon causes dilation of the bell shaped sleeve, whereas deflation of the balloon separates the wall of the balloon from the dilated bell shaped sleeve.
摘要翻译：一种气球导管，其包括在腔的远端处的可膨胀气囊，用于允许流体通过所述可膨胀气囊以使所述气囊膨胀，所述气囊导管还包括覆盖所述气囊导管的气囊的钟形套筒，气球导致所述套筒膨胀，而随后通过提取流体而使气囊放气，导致气囊与扩张的钟形套筒分离，并且具有圆周壁的钟形套筒具有用于覆盖气球的圆周壁由管腔充气的气囊导管; 钟形套筒具有紧密围绕内腔的封闭近端和敞开的远端，使得气囊的充气引起钟形套筒的膨胀，而气囊的放气将气囊的壁与扩张的钟形分隔开袖。

9. 发明申请

WO2011089599A1 BALLOON CATHETER SYSTEM AND METHODS OF MAKING AND USE THEREOF 审中-公开
标题翻译：气体导管系统及其制造和使用方法
公开(公告)号：WO2011089599A1
公开(公告)日：2011-07-28
申请号：PCT/IL2011/000060
申请日：2011-01-19
申请人： ANGIOSLIDE LTD. , HARARI, Eran , BARASH, Alexander , BERNSTEIN, Gil
发明人： HARARI, Eran , BARASH, Alexander , BERNSTEIN, Gil
IPC分类号： A61M29/00
CPC分类号： A61M25/0097 , A61M25/1006 , A61M25/10181 , A61M25/10182 , A61M25/10184 , A61M25/1027 , A61M2025/0004 , A61M2025/0175 , A61M2025/1065 , Y10T29/49826
摘要： A catheter system having an intussuscepting balloon and a handle for a catheter system. The handle includes a fluidic system for preventing overpressure conditions during balloon intussuscepting and includes a locking mechanism disposed outside of the fluidic system for preventing unintended or accidental movements of a plunger assembly included in the fluidic system. The system includes standard sized components and non-standard sized components. During handle assembly, specific sizes of non-standard sized components are selected to match the length and/or the diameter of a specific selected balloon and are assembled with the standard sized components to form the catheter system.
摘要翻译：导管系统，其具有套叠气囊和用于导管系统的手柄。手柄包括用于防止气囊套叠期间的超压状况的流体系统，并且包括设置在流体系统外部的锁定机构，用于防止包括在流体系统中的柱塞组件的意外或意外移动。该系统包括标准尺寸的组件和非标准尺寸组件。在手柄组件期间，选择特定尺寸的非标尺寸部件以匹配特定选定球囊的长度和/或直径，并与标准尺寸的部件组装以形成导管系统。

10. 发明申请

WO2010001405A1 CORRUGATED BALLOON CATHETER AND METHODS OF USE THEREOF 审中-公开
标题翻译：腐蚀性气泡导管及其使用方法
公开(公告)号：WO2010001405A1
公开(公告)日：2010-01-07
申请号：PCT/IL2009/000668
申请日：2009-07-02
申请人： ANGIOSLIDE LTD. , HARARI, Eran , BESSER, Doron
发明人： HARARI, Eran , BESSER, Doron
IPC分类号： A61B17/22
CPC分类号： A61M25/10182 , A61B17/22032 , A61B17/320725 , A61B2017/22038 , A61M25/1002 , A61M25/1006 , A61M25/10185 , A61M25/10186 , A61M2025/0008 , A61M2025/1068 , A61M2025/1086
摘要： lA balloon catheter including an outer conduit, an inner conduit disposed within the lumen of the outer conduit. The distal tip of the inner conduit extends beyond the distal tip of the outer conduit. The inner conduit is capable of being longitudinally moved within the outer conduit. An inflatable balloon has a proximal margin attached to the outer surface of the outer conduit's distal tip, and a distal margin attached to the outer surface of the portion of inner conduit extending beyond the distal tip of the outer conduit. The balloon has at least one corrugated portion. The distal end portion of the balloon is capable of intussuscepting upon proximal movement of the inner conduit within the outer conduit. The catheter has a fluid port for introducing an inflation fluid into the space formed between the outer conduit and the inner conduit and into the lumen of the balloon.
摘要翻译： l气囊导管，其包括外导管，设置在外导管的内腔内的内导管。内管道的远端延伸超出外导管的远端。内导管能够在外导管内纵向移动。可膨胀气囊具有附接到外导管的远侧末端的外表面的近侧边缘，以及附接到内导管部分的外表面的远侧边缘，其延伸超过外导管的远端。气球具有至少一个波纹部分。球囊的远端部分能够在外导管内部内导管的近端运动时套叠。导管具有用于将充气流体引入形成在外部管道和内部导管之间的空间并进入气囊的内腔的流体端口。

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