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1. 发明申请

WO2010036788A3 METHOD AND APPARATUS FOR GRAFTING OF SKIN TISSUE 审中-公开
公开(公告)号：WO2010036788A3
公开(公告)日：2010-04-01
申请号：PCT/US2009/058194
申请日：2009-09-24
申请人： THE GENERAL HOSPITAL CORPORATION , ASRANI, Falguni , FARINELLI, William, A. , SHAH, Ajay , LIU, Vincent , ANDERSON, R., Rox
发明人： ASRANI, Falguni , FARINELLI, William, A. , SHAH, Ajay , LIU, Vincent , ANDERSON, R., Rox
IPC分类号： A61B17/322 , A61F2/10 , A61B17/00
摘要： Methods and apparatus are provided for affecting an appearance of skin by harvesting small portions of tissue from a donor (first) site and applying them at a recipient (second) site. A plurality of micrografts can be formed from a piece of graft tissue and attached to a dressing material. The dressing material can then be expanded to increase a separation distance between the micrografts, and the dressing material having spaced-apart micrografts attached thereto can be applied to a prepared recipient site. An apparatus can be provided that expands the dressing material using a pressurized fluid. A further method can include providing a suspension of small portions of graft tissue in a solution. The solution can be injected into blisters formed at a recipient (second) site and the tissue portions allowed to attach and proliferate. A method and apparatus can also be provided for forming corresponding blisters at a donor site and at a recipient site. The raised (removed) portions of the blisters can be removed and attached to a dressing material, and the portions from the donor (first) site can be placed onto the exposed blister areas at the recipient site.

2. 发明申请

WO2010036788A2 METHOD AND APPARATUS FOR GRAFTING OF SKIN TISSUE 审中-公开
标题翻译：摄取皮肤组织的方法和装置
公开(公告)号：WO2010036788A2
公开(公告)日：2010-04-01
申请号：PCT/US2009058194
申请日：2009-09-24
申请人： GEN HOSPITAL CORP , ASRANI FALGUNI , FARINELLI WILLIAM A , SHAH AJAY , LIU VINCENT , ANDERSON R ROX
发明人： ASRANI FALGUNI , FARINELLI WILLIAM A , SHAH AJAY , LIU VINCENT , ANDERSON R ROX
IPC分类号： A61B17/322 , A61B17/00 , A61F2/10
CPC分类号： A61B17/322 , A61B2017/00969 , A61B2017/3225 , A61F2/105
摘要： Methods and apparatus are provided for affecting an appearance of skin by harvesting small portions of tissue from a donor (first) site and applying them at a recipient (second) site. A plurality of micrografts can be formed from a piece of graft tissue and attached to a dressing material. The dressing material can then be expanded to increase a separation distance between the micrografts, and the dressing material having spaced-apart micrografts attached thereto can be applied to a prepared recipient site. An apparatus can be provided that expands the dressing material using a pressurized fluid. A further method can include providing a suspension of small portions of graft tissue in a solution. The solution can be injected into blisters formed at a recipient (second) site and the tissue portions allowed to attach and proliferate. A method and apparatus can also be provided for forming corresponding blisters at a donor site and at a recipient site. The raised (removed) portions of the blisters can be removed and attached to a dressing material, and the portions from the donor (first) site can be placed onto the exposed blister areas at the recipient site.
摘要翻译：提供了通过从供体（第一）部位收集少部分组织并将其施用于受体（第二）部位来提供影响皮肤外观的方法和装置。多个微移植物可由一块移植组织形成，并附着于敷料。然后可以将敷料材料膨胀以增加微移植物之间的间隔距离，并且具有连接到其上的间隔开的微移植物的敷料材料可以应用于制备的受体部位。可以提供一种使用加压流体来膨胀敷料材料的装置。另外的方法可以包括提供移植组织的小部分在溶液中的悬浮液。溶液可以注射到在受体（第二）部位形成的水疱中，并且组织部分允许附着和增殖。还可以提供一种方法和装置，用于在施主部位和受体部位处形成相应的水泡。泡罩的隆起（去除）部分可以被去除并附着到敷料材料上，并且来自供体（第一）部位的部分可以被放置在受体部位的暴露的吸塑区域上。

3. 发明申请

WO0242719A3 APPARATUS FOR CONTROLLING LASER PENETRATION DEPTH 审中-公开
标题翻译：用于控制激光穿透深度的装置
公开(公告)号：WO0242719A3
公开(公告)日：2002-08-22
申请号：PCT/US0144008
申请日：2001-11-21
申请人： GEN HOSPITAL , ANDERSON R ROX , DOMANKEVITZ YACOV
发明人： ANDERSON R ROX , DOMANKEVITZ YACOV
IPC分类号： G02B6/42 , A61B18/12 , A61B18/20 , A61B18/22 , A61N5/06 , B23K26/08 , H01S3/00 , H01S3/10
CPC分类号： A61B18/203 , A61B2018/00452 , A61B2018/2277
摘要： The invention features systems and tools for controlling the optical penetration depth (OPD) of laser energy, e.g., when delivering laser energy to target tissue in a patient. The systems and tools control the OPD by controlling the incident angle at which the laser energy (364) is delivered to the target area of the patient. Embodiments of the invention include an optical coupler (368) that permits a user to vary the incident angle and thereby selectably control the OPD of incident laser energy (364). Fabricating the optical coupler (368) to have a refractive index greater than that of the target tissue can enhance the range of selectable OPDs. The laser energy (364), which is delivered to the desired depth, can cause alteration of the target tissue by, e.g., heating, ablation, and/or photochemical reaction.
摘要翻译：本发明的特征在于用于控制激光能量的光穿透深度（OPD）的系统和工具，例如，当将激光能量递送至患者中的目标组织时。系统和工具通过控制激光能量（364）被传递到患者的目标区域的入射角来控制OPD。本发明的实施例包括允许用户改变入射角并由此可选择地控制入射激光能量（OP）的光学耦合器（368）（364）。制造光学耦合器（368）以具有大于目标组织的折射率的折射率可以增强可选择的OPD的范围。传递到期望深度的激光能量（364）可以通过例如加热，消融和/或光化学反应引起靶组织的改变。

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