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1. 发明申请

WO2012094251A2 DEVICE AND METHOD FOR SAMPLING BODILY FLUID FOR MEDICAL ANALYTES IN ULTRA LOW CONCENTRATIONS 审中-公开
标题翻译：用于超声波浓度的医用分析仪采集体液的装置和方法
公开(公告)号：WO2012094251A2
公开(公告)日：2012-07-12
申请号：PCT/US2011/068165
申请日：2011-12-30
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , LAHEY CLINIC FOUNDATION, INC. , CIMA, Michael, J. , EKCHIAN, Gregory, J. , VASSILIOU, Christophoros, C. , LIU, Vincent, H. , WALD, Christoph, Wald , FLACKE, Sebastian , GORDON, Fredric, D.
发明人： CIMA, Michael, J. , EKCHIAN, Gregory, J. , VASSILIOU, Christophoros, C. , LIU, Vincent, H. , WALD, Christoph, Wald , FLACKE, Sebastian , GORDON, Fredric, D.
IPC分类号： A61F2/01 , G01N33/53 , G01N33/543
CPC分类号： G01N1/34 , A61F2/01 , G01N33/5302 , G01N33/5306 , G01N33/54313 , G01N33/56983
摘要： Trapping devices and methods are provided for capturing a medical analyte, in blood or another biological fluid. The device may include a structural substrate and a binding agent, such as an antibody, affixed to the structural substrate, wherein the binding agent is capable of binding or attaching with a medical analyte, such as a viral particle, and the device is configured for placement in a biological cavity or vessel (containing a biological fluid) in a patient. The trapping device, which may be in a twisted coil shape, is configured to trap at least some of the medical analyte, such a viral particle, present in the biological fluid. The method may include deploying a trapping device into the patient's blood vessel; after a period following the deployment, removing the Uapping device from the biological cavity or blood vessel; and then analyzing the trapping device for the presence of the medical analyte.
摘要翻译：提供捕获装置和方法用于捕获血液或其它生物流体中的医学分析物。该装置可以包括结构底物和粘附到结构底物上的结合剂，例如抗体，其中结合剂能够与医学分析物例如病毒颗粒结合或附着，并且该装置被配置用于放置在患者体内的生物腔或血管（含有生物流体）中。可以处于扭曲线圈形状的捕获装置构造成捕获存在于生物流体中的至少一些医学分析物（例如病毒颗粒）。该方法可以包括将捕获装置部署到患者的血管中; 在部署之后经过一段时间后，从生物腔或血管中取出打击装置; 然后分析捕获装置是否存在医用分析物。

2. 发明申请

WO2011140193A1 IMPLANTABLE DISSOLVED OXYGEN SENSOR AND METHODS OF USE 审中-公开
标题翻译：可剥离氧化物传感器及其使用方法
公开(公告)号：WO2011140193A1
公开(公告)日：2011-11-10
申请号：PCT/US2011/035146
申请日：2011-05-04
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , LIU, Vincent, Hok , VASSILIOU, Christophoros, Christou , LING, Yibo , CIMA, Michael, J.
发明人： LIU, Vincent, Hok , VASSILIOU, Christophoros, Christou , LING, Yibo , CIMA, Michael, J.
IPC分类号： A61B5/145 , A61B5/055 , A61K49/06
CPC分类号： A61B5/14503 , A61B5/055 , A61B5/415 , A61B5/418 , A61K49/10 , G01R33/448 , G01R33/5601
摘要： A sensor is provided for measuring a dissolved oxygen concentration in vivo when implanted at a tissue site and in ex vivo applications. The sensor includes an article comprising a sensing medium retained within the implantable article by an oxygen- permeable material. The sensing medium comprises an MR contrast agent for oxygen. The sensor is configured to indicate the dissolved oxygen concentration of a fluid, e.g., in vivo at the tissue site, when subjected to an MR-based method.
摘要翻译：提供了一种传感器，用于在植入组织部位和离体应用时测量体内溶解氧浓度。传感器包括通过透氧材料包含保持在可植入物品内的传感介质的制品。感测介质包括用于氧气的MR造影剂。该传感器被配置为当经历基于MR的方法时，指示流体的溶解氧浓度，例如在组织部位的体内溶解氧浓度。

3. 发明申请

WO0225950A3 LOAD BALANCING AND MODE SELECTION IN A MULTI-PROCESSOR VIDEO TRANSCODER 审中-公开
标题翻译：多处理器视频转换器中的负载平衡和模式选择
公开(公告)号：WO0225950A3
公开(公告)日：2003-08-28
申请号：PCT/US0125878
申请日：2001-08-20
申请人： GEN INSTRUMENT CORP , LIU VINCENT , NEMIROFF ROBERT S , WU SIU-WAI , LUTHRA AJAY , WANG LIMIN
发明人： LIU VINCENT , NEMIROFF ROBERT S , WU SIU-WAI , LUTHRA AJAY , WANG LIMIN
IPC分类号： H04N7/26 , H04N7/50
CPC分类号： H04N19/40 , H04N19/156 , H04N19/42 , H04N19/436 , H04N19/61
摘要： An efficient processing system, such as for transcoding video data. In an embodiment that is suitable for single or multiple processor embodiments, a processing mode is set for each input video frame, e.g., as a full transcode mode (740), which uses motion compensation, a requantization mode (755), which avoids motion compensation, or a bypass mode (750). The processing mode selection is based on a number or processing cycles that are available to process a frame, and an expected processing requirement of the frame. The bypass or requantization modes are selected to avoid a buffer overflow of the processor.
摘要翻译：一种高效的处理系统，例如用于对视频数据进行代码转换。在适用于单个或多个处理器实施例的实施例中，为每个输入视频帧设置处理模式，例如，使用运动补偿的全代码转换模式（740），避免运动的重新排序模式（755）补偿或旁路模式（750）。处理模式选择基于可用于处理帧的数量或处理周期以及帧的预期处理要求。选择旁路或再量化模式以避免处理器的缓冲区溢出。

4. 发明申请

WO0228108A3 STATISTICAL REMULTIPLEXING WITH BANDWIDTH ALLOCATION AMONG DIFFERENT TRANSCODING CHANNELS 审中-公开
标题翻译：带有不同转码通道的带宽分配的统计重新映射
公开(公告)号：WO0228108A3
公开(公告)日：2002-10-31
申请号：PCT/US0127243
申请日：2001-09-04
申请人： GEN INSTRUMENT CORP , WU SIU-WAI , NEMIROFF ROBERT S , LIU VINCENT , LUTHRA AJAY
发明人： WU SIU-WAI , NEMIROFF ROBERT S , LIU VINCENT , LUTHRA AJAY
IPC分类号： H04N7/26 , H04N7/50 , H04N21/236 , H04N21/2365 , H04N7/24
CPC分类号： H04N21/23608 , H04N19/115 , H04N19/126 , H04N19/15 , H04N19/152 , H04N19/176 , H04N19/196 , H04N19/197 , H04N19/40 , H04N19/61 , H04N21/23655
摘要： An efficient statistical remultiplexer for processing a number of channels that include video data. In one aspect, transcoding of the video data is delayed while statistical information is obtained from the data. Bit rate need parameters for the data are determined based on the statistical information, and the video data is transcoded (110, 112, 200, 300) based on the respective bit rate need parameters following the delay. In another aspect, a transcoding bit rate for video frames is updated a plurality of times at successive intervals to allow a closer monitoring of the bit rate. Minimum and maximum bounds for the transcoding bit rate, e.g., for buffer overflow and underflow protection, are also updated in each interval. In another aspect, the pre-transcoding quantization scales of the macroblocks in a frame are scaled to provide corresponding new quantization scales of the macroblocks in a frame are scaled to provide corresponding new quantization scales for transcoding based on a ratio of pre-transcoding amount of data in the frame and a target, post-transcoding amount of data for the frame. The quantization scales are adjusted for different poritons of the frame as transcoding progresses to ensure that a minimum amount of transcoding bandwidth is allocated to each macroblock.
摘要翻译：一种高效的统计再复用器，用于处理包含视频数据的多个通道。在一个方面，视频数据的转码被延迟，同时从数据获得统计信息。基于统计信息确定数据的比特率需求参数，并且基于延迟之后的相应比特率需要参数对视频数据进行代码转换（110,112,200,300）。在另一方面，用于视频帧的转码比特率以连续的间隔多次更新以允许对比特率进行更密切的监视。转码比特率的最小和最大范围（例如，用于缓冲区溢出和下溢保护）也在每个间隔中更新。另一方面，缩放帧中宏块的预代码转换量化比例以提供帧中宏块的对应新量化比例，以基于预编码转换量的比率来缩放以提供用于转码的对应新量化比例帧和目标中的数据，帧的转码后数据量。量化比例随着代码转换的进行而针对帧的不同区域进行调整，以确保将最小量的代码转换带宽分配给每个宏块。

5. 发明申请

WO2002081060A2 VERFAHREN ZUR ABSORPTIVEN AUSSCHLEUSUNG VON AMMONIAK UND METHAN AUS SYNTHESEGAS 审中-公开
标题翻译：方法吸收性排放氨和甲烷气体来合成
公开(公告)号：WO2002081060A2
公开(公告)日：2002-10-17
申请号：PCT/EP2002/003812
申请日：2002-04-05
申请人： UHDE GMBH , WYSCHOFSKY, Michael , LIU, Vincent
发明人： WYSCHOFSKY, Michael , LIU, Vincent
IPC分类号： B01D53/00
CPC分类号： C01B3/501 , B01D53/1425 , B01D53/1493 , B01D53/229 , C01B3/025 , C01B3/52 , C01B2203/0405 , C01B2203/0415 , C01B2203/0465 , C01B2203/048 , C01B2203/146 , C01C1/0476 , Y02C20/20 , Y02P20/129 , Y02P20/52
摘要： Die Erfindung betrifft ein Verfahren zur absorptiven Ausschleusung von NH 3 und CH 4 aus einem Gas unter hohem Druck, welches zumindest NH 3 , H 2 und CH 4 enthält, mittels eines schwersiedenden, physikalisch wirkenden und regenerierbaren Lösungsmittels, welches Homologe der Alkylenglykol-alkyl-ether enthält und auch Wasser enthalten kann wobei die absorbierten Komponenten NH 3 , H 2 , N 2 und CH 4 in mindestens zwei weiteren Verfahrensschritten bei unterschiedlichen Drucken aus dem beladenen Lösungsmittel wieder abgetrieben werden, wobei mindestens eine NH 3 -reiche und mindestens eine CH 4 -reiche Gasfraktion aus dem Lösungsmittel abgezogen werden. Das Verfahren eignet sich besonders als Teil einer Anlage zur Herstellung von Ammoniak.
摘要翻译：本发明涉及用于从气体在高压下的NH 3和CH 4的吸收排放，其中含有至少NH3 H2和CH4，由高沸点的，物理作用和再生的溶剂含有亚烷基二醇烷基醚和水的同系物的装置的方法可以包含从溶剂中吸收的组分的NH 3，H 2，N 2和CH 4被从加载的溶剂再次驱除在至少两个另外的工艺步骤在不同的压力，至少一个NH3-丰富和至少一个CH4富含气体馏分被剥离。该方法特别适合作为用于生产氨的工厂的一部分。

6. 发明申请

WO2010036788A2 METHOD AND APPARATUS FOR GRAFTING OF SKIN TISSUE 审中-公开
标题翻译：摄取皮肤组织的方法和装置
公开(公告)号：WO2010036788A2
公开(公告)日：2010-04-01
申请号：PCT/US2009058194
申请日：2009-09-24
申请人： GEN HOSPITAL CORP , ASRANI FALGUNI , FARINELLI WILLIAM A , SHAH AJAY , LIU VINCENT , ANDERSON R ROX
发明人： ASRANI FALGUNI , FARINELLI WILLIAM A , SHAH AJAY , LIU VINCENT , ANDERSON R ROX
IPC分类号： A61B17/322 , A61B17/00 , A61F2/10
CPC分类号： A61B17/322 , A61B2017/00969 , A61B2017/3225 , A61F2/105
摘要： Methods and apparatus are provided for affecting an appearance of skin by harvesting small portions of tissue from a donor (first) site and applying them at a recipient (second) site. A plurality of micrografts can be formed from a piece of graft tissue and attached to a dressing material. The dressing material can then be expanded to increase a separation distance between the micrografts, and the dressing material having spaced-apart micrografts attached thereto can be applied to a prepared recipient site. An apparatus can be provided that expands the dressing material using a pressurized fluid. A further method can include providing a suspension of small portions of graft tissue in a solution. The solution can be injected into blisters formed at a recipient (second) site and the tissue portions allowed to attach and proliferate. A method and apparatus can also be provided for forming corresponding blisters at a donor site and at a recipient site. The raised (removed) portions of the blisters can be removed and attached to a dressing material, and the portions from the donor (first) site can be placed onto the exposed blister areas at the recipient site.
摘要翻译：提供了通过从供体（第一）部位收集少部分组织并将其施用于受体（第二）部位来提供影响皮肤外观的方法和装置。多个微移植物可由一块移植组织形成，并附着于敷料。然后可以将敷料材料膨胀以增加微移植物之间的间隔距离，并且具有连接到其上的间隔开的微移植物的敷料材料可以应用于制备的受体部位。可以提供一种使用加压流体来膨胀敷料材料的装置。另外的方法可以包括提供移植组织的小部分在溶液中的悬浮液。溶液可以注射到在受体（第二）部位形成的水疱中，并且组织部分允许附着和增殖。还可以提供一种方法和装置，用于在施主部位和受体部位处形成相应的水泡。泡罩的隆起（去除）部分可以被去除并附着到敷料材料上，并且来自供体（第一）部位的部分可以被放置在受体部位的暴露的吸塑区域上。

7. 发明申请

WO0225952A3 REGENERATION OF PROGRAM CLOCK REFERENCE DATA FOR MPEG TRANSPORT STREAMS 审中-公开
标题翻译： MPEG运输流程序时钟参考数据的再生
公开(公告)号：WO0225952A3
公开(公告)日：2002-07-04
申请号：PCT/US0127191
申请日：2001-08-31
申请人： GEN INSTRUMENT CORP , NEMIROFF ROBERT S , LIU VINCENT , WU SIU-WAI
发明人： NEMIROFF ROBERT S , LIU VINCENT , WU SIU-WAI
IPC分类号： H04N7/26 , H04N21/2343 , H04N21/236 , H04N21/2365 , H04N7/24 , H04N7/58
CPC分类号： H04N21/2365 , H04N19/40 , H04N21/2343 , H04N21/23608
摘要： A system for providing an accurate time reference for multiple input and output digital video signals of a transcoder (100) that is particularly suited for use with MPEG data. The multiple streams are synchronized with a single master system time clock (155) at the transcoder (100). Timing data from the master clock is compared to timing data from packets that are input to the transcoder to determine an offset (120, 130). In particular, timing data, such as a program clock reference (PCR) field, is recovered from packets (104) of different channels that are input to the transcoder (122, 132). For each channel, timing data is then provided for packets (106) that are output from the transcoder based on the offset and timing data of the master clock (155) at the respective output times. In particular, the adjusted timing data is determined as a sum of the offset and an associated hardware error, less a delay (PcrSysDla) associated with the transcoder, which includes a lookahead delay and a buffer delay. The associated hardware error represents an error of the master clock and/or a system time clock of an encoder that encoded the particular channel.
摘要翻译：一种用于为特别适合于与MPEG数据一起使用的代码转换器（100）的多个输入和输出数字视频信号提供准确的时间基准的系统。多个流与代码转换器（100）处的单个主系统时钟（155）同步。将来自主时钟的定时数据与来自输入到代码转换器的分组的定时数据进行比较以确定偏移（120,130）。具体地，诸如节目时钟参考（PCR）字段的定时数据从输入到代码转换器（122,132）的不同信道的分组（104）中恢复。对于每个通道，随后基于在相应输出时间的主时钟（155）的偏移和定时数据从代码转换器输出的分组（106）提供定时数据。特别地，调整的定时数据被确定为偏移量和相关联的硬件错误之和，减去与代码转换器相关联的延迟（PcrSysDla），其包括前瞻延迟和缓冲延迟。相关联的硬件错误表示编码特定信道的编码器的主时钟和/或系统时钟的错误。

8. 发明申请

WO0225951A2 METHOD AND APPARATUS FOR DETERMINING A TRANSMISSION BIT RATE IN A STATISTICAL MULTIPLEXER 审中-公开
标题翻译：用于确定统计多路复用器中的传输比率的方法和设备
公开(公告)号：WO0225951A2
公开(公告)日：2002-03-28
申请号：PCT/US0127171
申请日：2001-08-31
申请人： GEN INSTRUMENT CORP , LIU VINCENT , WU SIU WAI , CASTELOES MICHAEL , STONE ROBERT J , LAM REBECCA
发明人： LIU VINCENT , WU SIU-WAI , CASTELOES MICHAEL , STONE ROBERT J , LAM REBECCA
IPC分类号： H04N7/26 , H04N21/234 , H04N21/2365 , H04N21/434 , H04N21/44 , H04N7/24
CPC分类号： H04N21/23655 , H04N19/15 , H04N21/2401
摘要： A statistical multiplexer for coding and multiplexing multiple channels of digital television data, or multiple panels of HDTV digital television data. A bit rate need parameter is determined (102, 104, 106) for each encoder (112, 114, 116) in a stat mux group, and an encoding bit rate is allocated to each channel based on its need parameter. A transmission bit rate is allocated to each channel as a time-lagged version of its need parameter to minimize a rate mismatch between the output and the input of a decoder buffer (184). A packet processor (250, 350) checks for impending decoder buffer overflow or underflow events to set minimum and maximum limits on the transmission bit rate. Moreover, these limits are set based on whether a new transmission bit rate can be implemented before the decoding time stamp (DTS) of the current or next frame.
摘要翻译：用于编码和多路复用数字电视数据的多个通道或多个HDTV数字电视数据面板的统计多路复用器。确定静态多路复用组中的每个编码器（112,114,116）的比特率需求参数（102,104,106），并且基于其需要参数将编码比特率分配给每个信道。传输比特率作为其需要参数的时滞版本分配给每个信道，以最小化解码器缓冲器（184）的输出和输入之间的速率失配。分组处理器（250,350）检查即将发生的解码器缓冲器溢出或下溢事件，以设置传输比特率的最小和最大限制。此外，根据在当前帧或下一帧的解码时间戳（DTS）之前是否可以实现新的传输比特率来设置这些限制。

9. 发明申请

WO2003017677A3 VIDEO ENCODING METHOD 审中-公开
公开(公告)号：WO2003017677A3
公开(公告)日：2003-02-27
申请号：PCT/US2002/025296
申请日：2002-08-09
申请人： GENERAL INSTRUMENT CORPORATION , WU, Siu-Wai , LIU, Vincent
发明人： WU, Siu-Wai , LIU, Vincent
IPC分类号： H04N7/26
摘要： The invention relates to an improved system and method for encoding digital images within frames for digital television transmission. Every anchor frame in a first pass encoder is encoded as a P-frame. Groups of macroblocks, such as slices in the P-frame, are alternately encoded as I-slices and P-slices. This allows both I and P encoding complexity to be computed in a single pass, without having to encode the same frame twice. Accordingly, the I-frame decision can be made at a second pass encoder instead of at the first pass encoder, thus taking advantage of a look-ahead pipeline architecture to more effectively align the I-frames with scene changes.

10. 发明申请

WO02100110A2 SPLICING OF DIGITAL VIDEO TRANSPORT STREAMS 审中-公开
标题翻译：数字视频传输流的分布
公开(公告)号：WO02100110A2
公开(公告)日：2002-12-12
申请号：PCT/US0215499
申请日：2002-05-14
申请人： GEN INSTRUMENT CORP , LIU VINCENT , NEMIROFF ROBERT S , WU SIU-WAI
发明人： LIU VINCENT , NEMIROFF ROBERT S , WU SIU-WAI
IPC分类号： H04N21/234 , H04N21/236 , H04N21/81 , H04N7/24
CPC分类号： H04N21/23608 , H04N21/23424 , H04N21/812
摘要： A mechanism for splicing advertisements, local programming and the like into a digital video transport stream is provided. In order to achieve proper splicing, an appropriate number of frames is inserted between bitstream to properly close a GOP of the first bistream into which a second bitstream carrying the spliced content is inserted. Program clock references (PCRS) of the bitstreams are adjusted as necessary in order to force continuity between the bistreams. For inserting advertisements, the PCR of the program stream and ad stream can be tracked, and the PCR of the program stream can be used both before and after splicing. For local program insertion (which are typically substantially longer than advertisements), the PCR of the local program can be used, after adjustment thereof with an offset to maintain continuity at the splice point. The PTS an/or DTS of the inserted bistream can be modified to keep them continuous at the splice point for both video and audio streams. The spliced bitstream is transcoded to maintain a desired output bit rate, and to provide overflow/underflow protection of the video buffers.
摘要翻译：提供了一种用于将广告，本地编程等拼接成数字视频传输流的机制。为了实现适当的拼接，在比特流之间插入适当数量的帧以恰当地关闭插入了拼接内容的第二比特流的第一双向流的GOP。根据需要调整比特流的编程时钟参考（PCRS），以便强制双向传送器之间的连续性。为了插入广告，可以跟踪节目流和广播流的PCR，并且可以在拼接之前和之后使用节目流的PCR。对于本地程序插入（其通常比广告更长），可以使用本地程序的PCR进行调整之后使用偏移量来保持拼接点的连续性。可以修改插入的双向流的PTS a /或DTS，以使它们在视频和音频流的拼接点处保持连续。拼接的比特流被转码以保持期望的输出比特率，并提供视频缓冲器的溢出/下溢保护。

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