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1. 发明申请

WO2008060877A2 MEDICAL DEVICES AND RELATED METHODS 审中-公开
标题翻译：医疗器械及相关方法
公开(公告)号：WO2008060877A2
公开(公告)日：2008-05-22
申请号：PCT/US2007083573
申请日：2007-11-05
申请人： BOSTON SCIENT SCIMED INC , HOLMAN THOMAS J , SHIPPY III JAMES LEE , ALI AFSAR
发明人： HOLMAN THOMAS J , SHIPPY III JAMES LEE , ALI AFSAR
IPC分类号： A61M25/00 , A61M29/02
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

2. 发明申请

WO2006089115A1 MEDICAL DEVICES 审中-公开
标题翻译：医疗设备
公开(公告)号：WO2006089115A1
公开(公告)日：2006-08-24
申请号：PCT/US2006/005641
申请日：2006-02-16
申请人： BOSTON SCIENTIFIC SCIMED, INC. , KLISCH, Leo, M. , WEBER, Jan , HOLMAN, Thomas, J. , SCHEWE, Scott, R. , ALI, Afsar , NODDIN, Richard, A. , SHIPPY, James Lee, III , JAGGER, Karl , SEPPALA, Jan
发明人： KLISCH, Leo, M. , WEBER, Jan , HOLMAN, Thomas, J. , SCHEWE, Scott, R. , ALI, Afsar , NODDIN, Richard, A. , SHIPPY, James Lee, III , JAGGER, Karl , SEPPALA, Jan
IPC分类号： A61M25/00
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1029 , A61M25/1038 , A61M2025/1031 , A61M2025/1075 , A61M2025/1086 , A61M2025/1088
摘要： Medical devices, for example, those that have balloons, and methods of making the devices are described. In some embodiments, a method includes providing a medical balloon (100) having a first cone portion and a body portion (102), and removing material from an outer surface the body portion of the balloon such that the balloon includes a first region and a second region, the first region (108) being recessed relative to the second region (109).
摘要翻译：描述了医疗设备，例如具有气球的设备，以及制造设备的方法。在一些实施例中，一种方法包括提供具有第一锥形部分和主体部分（102）的医疗气囊（100），以及从气球的主体部分的外表面移除材料，使得气囊包括第一区域和第二区域，第一区域（108）相对于第二区域（109）凹进。

3. 发明申请

WO2009137384A3 INTRAVASCULAR MEDICAL DEVICES HAVING A BIORESORBABLE COATING LAYER WITH A PRE-DETERMINED PATTERN 审中-公开
标题翻译：具有预先确定的图案的具有可生物降解涂层的血管内医疗装置
公开(公告)号：WO2009137384A3
公开(公告)日：2010-08-19
申请号：PCT/US2009042666
申请日：2009-05-04
申请人： BOSTON SCIENT SCIMED INC , EDELMAN PETER , ALI AFSAR
发明人： EDELMAN PETER , ALI AFSAR
IPC分类号： A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61L31/148 , A61L31/10 , A61L31/16 , A61L2300/00
摘要： Intravascular medical devices comprising a coating layer disposed on a substrate associated with the medical device, wherein the coating layer has a pre-determined fragmentation pattern. At least a portion of the coating layer comprises a plurality of discontinuous bioresorbable members, wherein the discontinuous bioresorbable members have a size less than the luminal diameter of an arteriole. The coating layer may be formed by excavating portions of a coating layer (e.g., by laser ablation) to create gaps which define the discontinuous bioresorbable members. In certain embodiments, the coating layer is formed of a heat-bondable material. In such embodiments, the discontinuous bioresorbable members may be adhered to the substrate via heat bonds. Also disclosed are methods of forming a coating layer on medical devices and methods of treating intravascular sites.
摘要翻译：包括设置在与医疗装置相关联的衬底上的涂层的血管内医疗装置，其中所述涂层具有预定的碎裂模式。所述涂层的至少一部分包括多个不连续的生物可再吸收构件，其中所述不连续的生物可再吸收构件的尺寸小于小动脉的管腔直径。可以通过挖掘涂层的部分（例如通过激光烧蚀）来形成涂层以产生限定不连续生物可再吸收构件的间隙。在某些实施方案中，涂层由可热粘合的材料形成。在这样的实施例中，不连续的生物可再吸收构件可以通过热键粘附到基底上。还公开了在医疗装置上形成涂层的方法和治疗血管内部位的方法。

4. 发明申请

WO2008060877A3 MEDICAL DEVICES AND RELATED METHODS 审中-公开
公开(公告)号：WO2008060877A3
公开(公告)日：2008-05-22
申请号：PCT/US2007/083573
申请日：2007-11-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HOLMAN, Thomas J. , SHIPPY, III, James Lee , ALI, Afsar
发明人： HOLMAN, Thomas J. , SHIPPY, III, James Lee , ALI, Afsar
IPC分类号： A61M25/10 , A61M25/00
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.

5. 发明申请

WO2010003003A1 IMPLANTS INCLUDING FRACTAL STRUCTURES 审中-公开
标题翻译：包括断裂结构的植入物
公开(公告)号：WO2010003003A1
公开(公告)日：2010-01-07
申请号：PCT/US2009/049422
申请日：2009-07-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , HOLMAN, Tom , FENG, James Q. , WARNER, Robert W. , ALI, Afsar
发明人： ATANASOSKA, Liliana , HOLMAN, Tom , FENG, James Q. , WARNER, Robert W. , ALI, Afsar
IPC分类号： A61F2/86
CPC分类号： A61F2/86 , A61F2/0077
摘要： An endoprosthesis includes a member having a surface that includes a fractal structure.
摘要翻译：内假体包括具有包括分形结构的表面的构件。

6. 发明申请

WO2005099803A2 BALLOON CATHETERS AND METHODS FOR MANUFACTURING BALLOONS FOR BALLOON CATHETERS 审中-公开
标题翻译：用于制造气球的气球的气泡导管和方法
公开(公告)号：WO2005099803A2
公开(公告)日：2005-10-27
申请号：PCT/US2005/011460
申请日：2005-04-04
申请人： SCIMED LIFE SYSTEMS, INC. , ALI, Afsar , HORN, Daniel, J. , WEBER, Jan , SCHEWE, Scott, R.
发明人： ALI, Afsar , HORN, Daniel, J. , WEBER, Jan , SCHEWE, Scott, R.
IPC分类号： A61M25/00
CPC分类号： A61M25/1027 , A61M2025/1063 , B29C49/00 , B29C2035/0838 , B29C2035/0855 , B29C2049/0089 , B29C2791/001 , B29C2791/009 , B29K2105/258 , B29L2031/7542
摘要： Catheters, balloons, and methods of manufacturing balloons for balloon catheters using lasers are disclosed. A catheter with a shaft sized for use with a .014 inch guide wire includes a polymeric balloon having a body portion with an inflated outer diameter of more than 6 millimeters. An inflatable balloon includes an inflated outer diameter to inner waist diameter ratio of 12.5 to 1. An inflatable polymeric balloon that has a body portion with two regions that have different molecular orientations is also provided. A method of processing an elongate polymeric material includes heating a portion of the polymeric material with a laser while longitudinally stretching the portion of the polymeric material. A method of manufacturing a balloon includes heating and longitudinally stretching a first and second portion of an elongate polymeric tube to form first and second end portion. The remaining body portion is radially expanded to form the balloon.
摘要翻译：公开了使用激光器的球囊导管制造气球的导管，球囊和方法。具有适于与0.014英寸导丝一起使用的轴的导管包括具有膨胀外径大于6毫米的主体部分的聚合气囊。可充气气囊包括膨胀的外径至内腰直径比为12.5:1。还提供具有主体部分的充气聚合球囊，其具有不同分子取向的两个区域。处理细长聚合物材料的方法包括在纵向拉伸聚合物材料的一部分的同时用激光加热聚合材料的一部分。制造球囊的方法包括加热并纵向拉伸细长聚合物管的第一和第二部分以形成第一和第二端部。剩余的主体部分被径向扩张以形成气球。

7. 发明申请

WO2012057855A1 ENERGY STORAGE DEVICE FLUID APERATURE 审中-公开
标题翻译：能源储存装置流体动力学
公开(公告)号：WO2012057855A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/033958
申请日：2011-04-26
申请人： MEDTRONIC, INC. , ALI, Afsar, Mohammad , GUY, David, P. , PAPENFUSS, Jason, T. , MOHAN, Pankaj
发明人： ALI, Afsar, Mohammad , GUY, David, P. , PAPENFUSS, Jason, T. , MOHAN, Pankaj
IPC分类号： H01M2/02 , H01M2/36 , H01M10/04
CPC分类号： H01M2/0202 , H01M2/361 , H01M2/365 , H01M10/0436 , Y10T29/4911
摘要： An energy storage device may include a housing and a fluid access aperture extending through a sidewall of housing that is used to fill the device with electrolytic fluid. In some examples, the fluid access aperture may define a length extending through the housing that is greater than a major width that extends across a cross-sectional area of the fluid access aperture. In some additional examples, the fluid access aperture may be angled relative to an axis that is substantially orthogonal to the housing. Depending on the situation, such example fluid access apertures may prevent electrolytic fluid from escaping from the energy storage device while the fluid access aperture is being sealed.
摘要翻译：能量存储装置可以包括壳体和延伸穿过壳体的侧壁的流体通路孔，其用于将电解液填充到装置中。在一些示例中，流体通道孔可以限定延伸穿过壳体的长度，该长度大于穿过流体通道孔的横截面积延伸的主宽度。在一些另外的例子中，流体通道孔可以相对于基本上垂直于壳体的轴线成角度。根据情况，这种示例的流体通路孔可以防止电解液在密封流体进入孔时从储能装置逸出。

8. 发明申请

WO2009137384A2 MEDICAL DEVICES HAVING A BIORESORBABLE COATING LAYER WITH A PRE-DETERMINED PATTERN FOR FRAGMENTATION 审中-公开
标题翻译：具有预先确定的图案的可生物降解涂层的医疗装置
公开(公告)号：WO2009137384A2
公开(公告)日：2009-11-12
申请号：PCT/US2009/042666
申请日：2009-05-04
申请人： BOSTON SCIENTIFIC SCIMED, INC. , EDELMAN, Peter , ALI, Afsar
发明人： EDELMAN, Peter , ALI, Afsar
IPC分类号： A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61L31/148 , A61L31/10 , A61L31/16 , A61L2300/00
摘要： Intravascular medical devices comprising a coating layer disposed on a substrate associated with the medical device, wherein the coating layer has a pre-determined fragmentation pattern. At least a portion of the coating layer comprises a plurality of discontinuous bioresorbable members, wherein the discontinuous bioresorbable members have a size less than the luminal diameter of an arteriole. The coating layer may be formed by excavating portions of a coating layer (e.g., by laser ablation) to create gaps which define the discontinuous bioresorbable members. In certain embodiments, the coating layer is formed of a heat-bondable material. In such embodiments, the discontinuous bioresorbable members may be adhered to the substrate via heat bonds. Also disclosed are methods of forming a coating layer on medical devices and methods of treating intravascular sites.
摘要翻译：包括设置在与医疗装置相关联的衬底上的涂层的血管内医疗装置，其中所述涂层具有预定的碎裂模式。所述涂层的至少一部分包括多个不连续的生物可再吸收构件，其中所述不连续的生物可再吸收构件的尺寸小于小动脉的管腔直径。可以通过挖掘涂层的部分（例如通过激光烧蚀）来形成涂层以产生限定不连续生物可再吸收构件的间隙。在某些实施方案中，涂层由可热粘合的材料形成。在这样的实施例中，不连续的生物可再吸收构件可以通过热键粘附到基底上。还公开了在医疗装置上形成涂层的方法和治疗血管内部位的方法。

9. 发明申请

WO2005099803A3 BALLOON CATHETERS AND METHODS FOR MANUFACTURING BALLOONS FOR BALLOON CATHETERS 审中-公开
标题翻译：用于制造气球的气球的气泡导管和方法
公开(公告)号：WO2005099803A3
公开(公告)日：2006-04-27
申请号：PCT/US2005011460
申请日：2005-04-04
申请人： SCIMED LIFE SYSTEMS INC , ALI AFSAR , HORN DANIEL J , WEBER JAN , SCHEWE SCOTT R
发明人： ALI AFSAR , HORN DANIEL J , WEBER JAN , SCHEWE SCOTT R
IPC分类号： A61M25/00 , A61F2/958 , B29C35/08 , B29C49/00 , B29C49/14 , B29C49/44 , B29C55/00
CPC分类号： A61M25/1027 , A61M2025/1063 , B29C49/00 , B29C2035/0838 , B29C2035/0855 , B29C2049/0089 , B29C2791/001 , B29C2791/009 , B29K2105/258 , B29L2031/7542
摘要： A catheter (100) with a shaft (103) sized for use with a .014 inch guide wire (110) includes a polymeric balloon (102) having a body portion with an inflated outer diameter of more than 6 millimeters. An inflatable balloon includes an inflated outer diameter to inner waist diameter ratio of 12.5 to 1. An inflatable polymeric balloon that has a body portion with two regions that have different molecular orientations is also provided. A method of processing an elongate polymeric material includes heating a portion of the polymeric material with a laser while longitudinally stretching the portion of the polymeric material. A method of manufacturing a balloon includes heating and longitudinally stretching a first and second portion of an elongate polymeric tube to form first and second end portion. The remaining body portion is radially expanded to form the balloon.
摘要翻译：具有尺寸适于0.014英寸导丝（110）的轴（103）的导管（100）包括具有膨胀外径大于6毫米的主体部分的聚合物气囊（102）。可充气气囊包括膨胀的外径至内腰直径比为12.5:1。还提供具有主体部分的充气聚合球囊，其具有不同分子取向的两个区域。处理细长聚合物材料的方法包括在纵向拉伸聚合物材料的一部分的同时用激光加热聚合材料的一部分。制造球囊的方法包括加热并纵向拉伸细长聚合物管的第一和第二部分以形成第一和第二端部。剩余的主体部分被径向扩张以形成气球。

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