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1. 发明申请

WO2009134881A1 OPTIMIZING THERAPY OUTCOMES FOR PERITONEAL DIALYSIS 审中-公开
标题翻译：优化腹膜透析治疗结果
公开(公告)号：WO2009134881A1
公开(公告)日：2009-11-05
申请号：PCT/US2009/042106
申请日：2009-04-29
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , LO, Ying-cheng , AKONUR, Alp , MARTIS, Isaac
发明人： LO, Ying-cheng , AKONUR, Alp , MARTIS, Isaac
IPC分类号： A61M1/28 , G06F19/00
CPC分类号： G06F19/3481 , A61M1/28 , A61M1/281 , A61M1/282 , A61M2205/3569 , A61M2205/52 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , G06F19/00
摘要： Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient.
摘要翻译：已使用动力学建模计算透析患者腹膜腔中腹膜透析液的各种停留时间的腹膜透析治疗结果。每个患者的停留时间不应该相同，但应根据患者的状况和需要而有所不同。一些患者有可能在透析液中表达更大的超滤液，并且这些患者可以从更长的停留时间获益，而其他潜力较低的患者不会从更长的停留时间获益。观察每个腹膜透析治疗结果的最佳时间或高峰时间，例如超滤液体积速率，尿素清除率（Kt / V）和肌酸酐清除率，同时使碳氢化合物吸收最小化。这些数值和输入参数可用于为每位患者量身定制腹膜透析停留时间，估计峰值停留时间，从而为每位患者产生最佳治疗结果。

2. 发明申请

WO2009058727A1 DIALYSIS SYSTEM HAVING INTEGRATED PNEUMATIC MANIFOLD 审中-公开
标题翻译：具有集成气动歧管的透析系统
公开(公告)号：WO2009058727A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/081315
申请日：2008-10-27
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , CHAPMAN, Paul , CHILDERS, Robert , HECHT, Gideon , WELLINGS, Anders
发明人： CHAPMAN, Paul , CHILDERS, Robert , HECHT, Gideon , WELLINGS, Anders
IPC分类号： A61M1/28
CPC分类号： A61M1/1008 , A61M1/1037 , A61M1/1087 , A61M1/14 , A61M1/1621 , A61M1/1649 , A61M1/28 , A61M1/281 , A61M1/30 , A61M1/3624 , A61M2205/12 , A61M2205/128 , A61M2205/42 , B01J2219/00396 , B01J2219/00398 , B01J2219/00409 , B01J2219/00412 , F15B1/02 , F15B1/021 , F15B13/0807 , F15B13/0814 , F15B13/0817 , F15B13/0821 , F15B13/0825 , F15B13/0828 , F15B13/0832 , F15B13/0835 , F15B13/0842 , F15B21/006 , F15B21/008 , F16K99/0042 , F16K2099/0082 , F16K2099/0086 , Y10T137/86027
摘要： A dialysis machine valve manifold assembly (100) includes a plurality of pneumatic valves (120); a plate including a first side and a second side, the plurality of pneumatic valves mounted to the first side of the plate, the second side of the plate defining a plurality of pneumatic flow paths (138); and a port header (108) mounted removably to the plate, the port header including a plurality of ports (114) configured to connect sealingly to pneumatic tubing, wherein the ports are in fluid communication with the pneumatic valves via the pneumatic flow paths defined in the plate.
摘要翻译：透析机阀歧管组件（100）包括多个气动阀（120）; 包括第一侧和第二侧的板，所述多个气动阀安装在所述板的第一侧上，所述板的第二侧限定多个气动流路（138）; 以及可拆卸地安装到所述板的端口集管（108），所述端口集管包括被配置为密封地连接到气动管道的多个端口（114），其中所述端口经由所述气动阀流经所述气动流动路径碟子。

3. 发明申请

WO2009006504A2 DIALYSIS CASSETTE HAVING MULTIPLE OUTLET VALVE 审中-公开
标题翻译：具有多出口阀的透析盒
公开(公告)号：WO2009006504A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/068974
申请日：2008-07-02
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , STECK, John , REITZ, Douglas
发明人： STECK, John , REITZ, Douglas
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M2205/128
摘要： A disposable pumping cassette in one embodiment includes a pump chamber; and a valve chamber in communication with the pump chamber, the valve chamber including an inlet and first and second outlets. A disposable pumping cassette in another embodiment includes a first valve chamber including an inlet and first and second outlets; and a second valve chamber including an inlet and an outlet, the second valve chamber openable to allow dialysis fluid to flow through one of the first and second outlets of the first valve chamber, through the outlet of the second valve chamber. A disposable pumping cassette in a further embodiment includes a valve chamber including a fluid inlet and first and second fluid outlets; and a flexible sheet openable to open and close only one of the first and second outlets.
摘要翻译：在一个实施例中的一次性泵送盒包括泵室; 以及与泵室连通的阀室，该阀室包括入口以及第一和第二出口。在另一个实施例中的一次性泵送盒包括：第一阀室，其包括入口以及第一和第二出口; 以及包括入口和出口的第二阀室，第二阀室可打开以允许透析流体通过第二阀室的出口流过第一阀室的第一和第二出口中的一个。在另一个实施例中的一次性泵送盒包括阀室，该阀室包括流体入口以及第一和第二流体出口; 以及可打开以仅打开和关闭第一和第二出口中的一个的柔性片。

4. 发明申请

WO2009006502A2 DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE AND HEATED CASSETTE INTERFACE 审中-公开
标题翻译：具有一次性盒和加热盒接口的透析系统
公开(公告)号：WO2009006502A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/068969
申请日：2008-07-02
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , CHILDERS, Robert , HUITT, Bruce
发明人： CHILDERS, Robert , HUITT, Bruce
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M1/284 , A61M1/288 , A61M2205/128 , A61M2205/3396 , A61M2209/084
摘要： A dialysis fluid flow control system includes a pumping cassette interface including a pump area operable with a pump chamber of a disposable cassette; the cassette interface further including a volumetric reference chamber used in a volumetric control of a dialysis fluid pumped pneumatically into and out of the pump chamber of the disposable cassette; a heater connected operably to the cassette interface; and a controller connected operably to the heater so as to cause the heater to heat at least a portion of the cassette interface to a desired temperature.
摘要翻译：透析液流量控制系统包括：泵送盒接口，其包括可与一次性盒的泵室一起操作的泵区; 所述盒接口进一步包括容积参考腔室，所述容积参考腔室用于对通过所述一次性盒子的所述泵腔室气动地泵入和泵出的透析流体的容积控制; 可操作地连接到盒接口的加热器; 以及与加热器可操作地连接的控制器，以使加热器将盒接口的至少一部分加热到期望的温度。

5. 发明申请

WO2009006491A2 "RADIO FREQUENCY AUTO-IDENTIFICATION SYSTEM" 审中-公开
标题翻译： “无线电频率自动识别系统”
公开(公告)号：WO2009006491A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/068950
申请日：2008-07-02
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , KNEIP, Daniel , WEST, David , CUMMINGS, David , LEE, Patrick , MURPHY, Randy
发明人： KNEIP, Daniel , WEST, David , CUMMINGS, David , LEE, Patrick , MURPHY, Randy
IPC分类号： A61M1/16
CPC分类号： G06K7/0008 , A61M1/28 , A61M2205/12 , A61M2205/3569 , A61M2205/3592 , A61M2205/6054 , G06K7/10316
摘要： A medical fluid delivery system includes a dialysis instrument; a disposable pumping cassette operable with a pumping actuator of the dialysis instrument, the disposable cassette including or connected fluidly to a plurality of first connectors; a plurality of second connectors configured to interface with the first connectors, each second connector associated with a radio frequency ("RFID") tag; and electronics configured to read the RFID tags via a plurality of antennae and to identify that each of the second connectors is positioned properly with respect to a proper one of the first connectors.
摘要翻译：药液输送系统包括透析仪器; 一次性抽吸盒，其可与所述透析仪器的泵送致动器一起操作，所述一次性盒包括流体地连接到多个第一连接器; 多个第二连接器，被配置为与第一连接器接口，每个第二连接器与射频（“RFID”）标签相关联; 以及经配置以经由多个天线读取RFID标签并且识别每个第二连接器相对于适当的第一连接器正确定位的电子器件。

6. 发明申请

WO2008100983A2 "DIALYSIS SYSTEM HAVING VIDEO DISPLAY WITH AMBIENT LIGHT ADJUSTMENT" 审中-公开
标题翻译： “具有环境亮度调整的视频显示的分析系统”
公开(公告)号：WO2008100983A2
公开(公告)日：2008-08-21
申请号：PCT/US2008/053796
申请日：2008-02-13
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , ALBERTI, James, J. , GILBERT, Rick , HOPPING, Pete , BEDINGFIELD, John
发明人： ALBERTI, James, J. , GILBERT, Rick , HOPPING, Pete , BEDINGFIELD, John
IPC分类号： A61M1/28 , G09G3/34
CPC分类号： G09G3/3406 , A61M1/1621 , A61M1/28 , A61M1/284 , A61M1/288 , A61M2205/12 , A61M2205/33 , A61M2205/502 , A61M2205/505 , A61M2205/587 , G09G2320/0626 , G09G2360/144
摘要： A medical therapy machine includes: an enclosure; a medical therapy machine component located inside the enclosure; a video monitor supported by the enclosure and displaying at least one of information and indicia relating to the medical therapy; an ambient light sensor positioned with respect to the enclosure so as to be able to sense a level of ambient light impinging the enclosure; and a logic implementor configured to control a level of backlight brightness for the video monitor based on the level of ambient light sensed by the sensor.
摘要翻译：医疗治疗机包括：外壳; 位于外壳内的医疗机构部件; 由所述外壳支持的视频监视器，并且显示与所述医学治疗相关的信息和标记中的至少一个; 相对于外壳定位的环境光传感器，以便能够感测撞击外壳的环境光的水平; 以及逻辑实现器，被配置为基于由所述传感器感测的环境光的水平来控制所述视频监视器的背光亮度的水平。

7. 发明申请

WO2008100981A1 "DIALYSIS SYSTEM HAVING INDUCTIVE HEATING" 审中-公开
标题翻译： “具有感应加热的透析系统”
公开(公告)号：WO2008100981A1
公开(公告)日：2008-08-21
申请号：PCT/US2008/053791
申请日：2008-02-13
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , PRISCO, Michael, R. , DING, Yuanpang, S. , CHOU, Tan-Cheng , JOHNSON, Tom
发明人： PRISCO, Michael, R. , DING, Yuanpang, S. , CHOU, Tan-Cheng , JOHNSON, Tom
IPC分类号： A61M1/16 , A61M5/44 , A61M5/14 , A61M1/36
CPC分类号： A61M5/44 , A61M1/16 , A61M1/1605 , A61M2205/127 , A61M2205/3368 , A61M2205/3653 , A61M2205/50
摘要： A medical fluid machine includes (i) a pump that pumps a medical fluid and (ii) a heater that heats the medical fluid, the heater including an electrically insulative housing, at least one flat sheet of electrically conductive material suitable for contacting the medical fluid, the sheet disposed within the insulative housing, the sheet defining a flow path for the medical fluid in which the medical fluid changes direction at least one time, a primary coil of a transformer located outside the insulative housing, the primary coil configured to induce a current into the at least one conductive sheet, creating heat that may be transferred to the medical fluid.
摘要翻译：医疗流体机器包括（i）泵送医疗流体的泵和（ii）加热医疗流体的加热器，加热器包括电绝缘壳体，至少一个电的平板适于接触医用流体的导电材料，设置在绝缘外壳内的片材，限定用于医疗流体的流动路径的片材，其中医用流体至少一次改变方向，变压器的初级线圈位于绝缘外壳的外部，所述初级线圈被配置为将电流引入所述至少一个导电片中，产生可传递至所述医用流体的热量。

8. 发明申请

WO2008100978A2 DIALYSIS SYSTEM HAVING DISPLAY WITH ELECTROMAGNETIC COMPLIANCE ("EMC") SEAL 审中-公开
标题翻译：具有电磁兼容性（“EMC”）密封的显示器的透析系统
公开(公告)号：WO2008100978A2
公开(公告)日：2008-08-21
申请号：PCT/US2008/053786
申请日：2008-02-13
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , BEDINGFIELD, John
发明人： BEDINGFIELD, John
IPC分类号： H05K9/00 , A61M1/00
CPC分类号： H05K9/0096 , H05K9/0094
摘要： A medical machine includes: an enclosure defining an opening, at least a portion of the enclosure being electrically conductive and acting as a first capacitor plate; a medical device component located inside the enclosure; a window placed adjacent to the opening; a video display with an at least partially conductive case acting as a second capacitor plate; and a dielectric member placed between the first and second capacitor plates, the plates and dielectric member forming a capacitor configured to prevent leakage of electromagnetic energy from the enclosure.
摘要翻译：医疗机器包括：限定开口的外壳，所述外壳的至少一部分是导电的并且用作第一电容器板; 位于外壳内的医疗器械部件; 邻近开口放置的窗户; 视频显示器，其具有用作第二电容器板的至少部分导电的外壳; 以及放置在第一和第二电容器板之间的电介质构件，所述板和电介质构件形成电容器，其构造成防止电磁能量从外壳泄漏。

9. 发明申请

WO2004016313A1 USER-FRIENDLY CATHETER CONNECTION ADAPTERS FOR OPTIMIZED CONNECTION TO MULTIPLE LUMEN CATHETERS 审中-公开
标题翻译：用户友好的导管连接适配器，用于优化连接到多个灯罩
公开(公告)号：WO2004016313A1
公开(公告)日：2004-02-26
申请号：PCT/US2003/025223
申请日：2003-08-13
申请人： BAXTER INTERNATIONAL, INC. , BAXTER HEALTHCARE S.A.
发明人： SEESE, Timothy, M. , GRISWOLD, William , RUDDELL, Scott
IPC分类号： A61M39/12
CPC分类号： A61M39/10 , A61M1/285 , A61M25/0014 , A61M25/0032 , A61M39/1011 , A61M39/105 , A61M39/12 , A61M2025/0031 , A61M2039/1027 , A61M2039/1072 , A61M2039/1077 , A61M2039/1094 , A61M2205/6045
摘要： A catheter connection adapter (10) is provided which allows for a user-friendly and mistake-proof connection of a multiple lumen catheter from a dialysis patient to a source of dialysis fluid. The connection adapter contains at least two ports (14, 16), e.g., one for inflow and one for outflow, and may have a tapered gap (12) between the ports so that an interference fit is made when the ports are inserted into the catheter. In addition, the ports may have a unique key and lock configuration with the catheter such that a fit can only be made when the catheter lumens and the ports are in proper alignment, and the ports may be unconnected to one another so as to provide separate fluid paths for inflow or outflow. The connection adapters are advantageous in that they will allow a multiple lumen catheter to be manually connected to other dialysis equipment following implantation in a patient.
摘要翻译：提供导管连接适配器（10），其允许多腔导管从透析患者到透析液源的用户友好且防错误的连接。连接适配器包含至少两个端口（14,16），例如一个用于流入，一个用于流出，并且可以在端口之间具有锥形间隙（12），使得当端口插入到端口时进行过盈配合导管。此外，端口可以具有与导管相关的独特的键和锁定配置，使得仅当导管腔和端口正确对准时才能进行配合，并且端口可以彼此不连接，以便提供单独的用于流入或流出的流体路径。连接适配器是有利的，因为它们将允许在植入患者体内后将多内腔导管手动连接到其它透析设备。

10. 发明申请

WO2003105944A1 LUER-ACTUATED CONNECTOR WITH MEMBRANE AND CONTAINER USING THE CONNECTOR 审中-公开
标题翻译：带连接器的带膜和容器的致动连接器
公开(公告)号：WO2003105944A1
公开(公告)日：2003-12-24
申请号：PCT/US2003/017619
申请日：2003-05-28
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A.
发明人： ANDERSON, Keith M.K. , CASTELLANOS, Raf , HURST, Bill , LING, Michael T.K. , MARCQUENSKI, Dan , SCHARF, Michael W. , MASEK, Jennifer L. , MARN, Gregory Thomas
IPC分类号： A61M39/10
CPC分类号： A61J1/10 , A61M39/18 , A61M2039/1027 , A61M2205/58 , A61M2205/581 , A61M2205/582 , Y10T137/1632 , Y10T137/1767
摘要： A connector, a container (10) using the connector and a method for establishing fluid communication with a container. The connector may include a first coupling member (14) and a second coupling member (28). The container may attach to the first coupling member. The first coupling member (14) may have a first passageway (16) with a spike (62) and a membrane (68) located therein. The second coupling member may have a second passageway. The first coupling member may engage the second coupling member and may further pierce the membrane with the spike (62). The first coupling member may further have a female end (42) of a luer-lock, and the second coupling member may have a male end (44) of a luer-lock. The first coupling member and the second coupling member may be engaged by twisting the male end and the female end of the coupling members to form the connector and establish fluid communication with the container.
摘要翻译：连接器，使用连接器的容器（10）和用于与容器建立流体连通的方法。连接器可以包括第一联接构件（14）和第二联接构件（28）。容器可以附接到第一联接构件。第一联接构件（14）可以具有第一通道（16），其具有钉（62）和位于其中的隔膜（68）。第二联接构件可以具有第二通道。第一联接构件可以接合第二联接构件并且可以用尖钉（62）进一步刺穿膜。第一联接构件还可以具有鲁尔锁的阴端（42），并且第二联接构件可以具有鲁尔锁的阳端（44）。第一联接构件和第二联接构件可以通过扭转联接构件的阳端和阴端而形成连接器并与容器建立流体连通。

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