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    • 4. 发明申请
    • DEVICE, KIT AND METHOD FOR CLOSURE OF A BODY LUMEN PUNCTURE
    • 装置,套件和方法,用于关闭身体灯泡
    • WO2011027003A1
    • 2011-03-10
    • PCT/EP2010/063135
    • 2010-09-07
    • JÖNSSON, Anders
    • JÖNSSON, Anders
    • A61B17/00A61F2/82A61F2/84
    • A61B17/0057A61B2017/00579A61B2017/00597A61B2017/00637A61B2017/00659A61B2017/00889A61B2017/00893
    • A medical device and method for closure of a puncture in a body lumen are disclosed. The device has an aggregate (10) of a support structure (20) and a substantially fluid tight patch member (30) attached thereto at an attachment unit (40). The aggregate has a first, temporary delivery shape,for delivery to an interior of said body lumen and to be subsequently subjected to a change of shape to a second shape, which is a tubular shape. When delivered in said body lumen, the patch member is arranged radially outside of said tubular support structure and arranged towards an inner tissue wall of the body lumen. The aggregate is the detached from a delivery device and said puncture is intraluminally closed in a leakage tight manner, advantageously supported by a physiological pressure of a body fluid in said body lumen. The device may biodegrade over time.
    • 公开了一种用于封闭体腔中的穿刺的医疗装置和方法。 该装置具有支撑结构(20)的集合体(10)和在附接单元(40))附接到其上的基本上流体密封的贴片构件(30)。 聚集体具有第一临时输送形状,用于输送到所述体腔的内部,并随后经受形状变化为管状形状的第二形状。 当递送在所述体腔中时,补片部件设置在所述管状支撑结构的径向外侧并且朝向体腔的内部组织壁布置。 聚集体是从输送装置分离出来的,并且所述穿刺以泄漏密封的方式内腔闭合,有利地由所述体腔内的体液的生理压力支撑。 该设备可能随时间生物降解。
    • 6. 发明申请
    • ENDOLUMINAL MEDICAL ACCESS DEVICE
    • 内镜医疗访问装置
    • WO2009124990A1
    • 2009-10-15
    • PCT/EP2009/054273
    • 2009-04-08
    • Karolinska Institutet Innovations ABHOLMIN, StaffanJONSSON, StefanLUNDBERG, Johan
    • HOLMIN, StaffanJONSSON, StefanLUNDBERG, Johan
    • A61M25/00A61M25/06
    • A61B17/3423A61B10/04A61B17/3494A61B2017/3425A61B2017/3492A61B2018/1892A61M25/0068A61M25/0069A61M25/0082A61M25/0084A61M25/06A61M2025/0042A61N1/05
    • An endoluminal medical access device (1) is disclosed that is devised for endoluminal delivery to an extravascular target site (5) at a vasculature site of a human or animal body vasculature, such as the microvasculature. The device (1 ) comprises a hollow body (112) arranged around a continuous channel (113) that ends in a distal end (100) and comprises a distal penetration portion (102) that is devised to extend across a tissue wall of said microvasculature said microvasculature site (4) at an extravascular target site in said body to provide communication with said extravascular target site through said channel (113) and devised for at least partly apposition to said tissue wall, and a proximal connection section (101 ), which proximally adjoins said penetration portion (102), and optionally comprises an intrusion depth limit unit (116, 118) and/or a hollow separation section (115) devised to provide a controllable separation of the penetration portion (102) from a connected proximal portion (110) of the hollow body.
    • 公开了一种管腔内医疗进入装置(1),其被设计用于在诸如微血管系统的人或动物体脉管系统的脉管系统部位处的血管内递送到血管外靶点部位(5)。 装置(1)包括围绕连续通道(113)布置的中空本体(112),其终止于远端(100)并且包括远端穿透部分(102),其设计成延伸穿过所述微血管的组织壁 所述微血管系统位点(4)位于所述体内的血管外靶点部位,以通过所述通道(113)提供与所述血管外靶点部位的连通性,并设计用于至少部分地与所述组织壁连接;以及近端连接部分(101) 近端邻接所述穿透部分(102),并且可选地包括入侵深度限制单元(116,118)和/或空心分离部分(115),其设计成提供穿透部分(102)与连接的近端部分 (110)。
    • 7. 发明申请
    • TOPICAL TERMAL DELIVERY DEVICE FOR NITRIC OXIDE DELIVERY
    • 用于氮氧化物输送的局部输送装置
    • WO2008116497A1
    • 2008-10-02
    • PCT/EP2007/052923
    • 2007-03-27
    • NOLabs ABLINDGREN, LarsMÅRLIND, LindaTHORSEN, Rikard
    • LINDGREN, LarsMÅRLIND, LindaTHORSEN, Rikard
    • A61K9/70A61L15/44A61K33/00
    • A61K9/703A61F2013/00646A61K9/7084A61K33/00A61L15/44A61L2300/114A61L2300/602A61M35/00
    • A topical dermal delivery device, such as a patch, for topical delivery of nitric oxide (NO) to treatment sites of mammals is disclosed. In an embodiment the patch has three layers; a backing with an activation window, a absorbent core as a reservoir and an NO permeable membrane with an adhesive layer towards the skin. The NO donor is applied into the device as a solution prior to application through the activation window. The window is closed after activation and the lid and backing is non-permeable for NO in order to increase the partial pressure of NO and thus the concentration of dissolved NO. The patch is fixated on the area to be treated with an adhesive layer that also assures sufficient contact throughout the treatment. The generated NO moves within the patch and can escape through the NO permeable membrane towards the area to be treated. Depending on therapy needed, the patch release curve differs and is chosen accordingly.
    • 公开了用于将一氧化氮(NO)局部递送到哺乳动物的处理部位的局部皮肤递送装置,例如贴片。 在一个实施例中,贴片具有三层; 具有活化窗的背衬,作为储存器的吸收芯和具有朝向皮肤的粘合剂层的NO可渗透膜。 NO供体在通过激活窗口施加之前作为解决方案施加到设备中。 活化后窗口关闭,盖子和背衬对于NO是不可渗透的,以增加NO的分压,从而增加溶解NO的浓度。 该贴片固定在待处理的区域上,该粘合剂层在整个治疗过程中也保证足够的接触。 所产生的NO在贴片内移动,并且可以通过NO渗透膜向待处理的区域逸出。 根据需要的治疗,补片释放曲线不同,并相应地选择。
    • 8. 发明申请
    • METHOD AND APPARATUS FOR COLLECTION OF WASTE ANESTHETIC GASES
    • 用于收集废气麻醉气体的方法和装置
    • WO2008104218A1
    • 2008-09-04
    • PCT/EP2007/051838
    • 2007-02-27
    • MAQUET CRITICAL CARE ABAHLMÉN, ChristerBROBORG, Stefan
    • AHLMÉN, ChristerBROBORG, Stefan
    • A61M16/00
    • A61M16/009A61M16/0093A61M2016/003G01F1/26
    • An apparatus (200) for collection of waste anesthetic gases, and a method of using such an apparatus are disclosed. The apparatus (200) has a gas collection chamber (60) with an input port (51, 61) to be connected to an exhaust of an anesthesia delivery system (4) for receiving a first gas flow (70) therefrom which includes a waste anesthetic gas component; an output port (62) from the gas collection chamber (60) to be connected to a vacuum system (8) for evacuation of an evacuation gas flow (71) from the gas collection chamber (60); and a bidirectional port (63) to and from the gas collection chamber (60), which has an adsorbing unit (21) connecting the gas collection chamber (60) with an ambient environment surrounding the gas collection chamber (60). The apparatus (200) provides for safe prevention of discharge of exhaled anesthetic gases into an ambient atmosphere surrounding the apparatus (200).
    • 公开了一种用于收集废麻醉气体的装置(200)以及使用这种装置的方法。 该设备(200)具有一个具有输入端口(51,61)的气体收集室(60),该输入端口连接到麻醉输送系统(4)的排气口,用于从其中接收包括废物的第一气流 麻醉气体成分; 来自气体收集室(60)的输出端口(62)连接到用于从气体收集室(60)排出抽空气体流(71)的真空系统(8)。 以及与气体收集室(60)的双向口(63),其具有将气体收集室(60)与围绕气体收集室(60)的周围环境连接的吸附单元(21)。 装置(200)提供安全防止将呼出的麻醉气体排放到设备(200)周围的环境大气中。