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1. 发明申请

WO2005051433A1 METHOD FOR TREATING HUMAN TUMOR CELLS WITH A NEWCASTLE DISEASE VIRUS STRAIN AND A CHEMOTHERAPEUTIC AGENT 审中-公开
标题翻译：用新型流感病毒病毒株和化疗药物治疗人类肿瘤细胞的方法
公开(公告)号：WO2005051433A1
公开(公告)日：2005-06-09
申请号：PCT/US2004/039789
申请日：2004-11-23
申请人： UNITED CANCER RESEARCH INSTITUTE , CSATARY, Laszlo, K. , SZEBERENYI, Joseph , FABIAN, Zsolt
发明人： CSATARY, Laszlo, K. , SZEBERENYI, Joseph , FABIAN, Zsolt
IPC分类号： A61K48/00
CPC分类号： A61K35/768 , A61K31/475 , A61K31/519 , A61K31/655 , A61K33/24 , A61K38/14 , A61K45/06 , C12N2760/18132 , A61K2300/00
摘要： A method for treating human tumor cells to induce apoptotic cell death thereof includes the step of infecting the tumor cells with a combination of the Herefordshire strain of Newcastle Disease Virus and a chemotherapeutic agent. The range of concentrations of chemotherapeutic agent/Herefordshire strain is in the range of 100/1 to 1/1. Illustrative chemotherapeutic agents include cisplatin, methotrexate, vincristine, bleomycin and dacarbazine.
摘要翻译：治疗人肿瘤细胞以诱导其凋亡细胞死亡的方法包括用Herefordshire株新城疫病毒与化学治疗剂的组合感染肿瘤细胞的步骤。化疗剂/赫里福德郡菌株的浓度范围在100/1至1/1的范围内。说明性的化学治疗剂包括顺铂，甲氨蝶呤，长春新碱，博来霉素和达卡巴嗪。

2. 发明申请

WO2003016176A1 INSERTABLE TRAY FOR A MULTIPLE DISC STORAGE CONTAINER 审中-公开
标题翻译：多个托盘存储容器的插入托盘
公开(公告)号：WO2003016176A1
公开(公告)日：2003-02-27
申请号：PCT/US2002/026048
申请日：2002-08-16
申请人： WESTVACO CORPORATION
发明人： RUFO, George, F., Jr. , BOLOGNIA, David, Louis
IPC分类号： B65D85/57
CPC分类号： G11B33/0427 , G11B33/045
摘要： A tray (14) for holding multiple discs within a storage container which, desirably, is a conventional single disc jewel box (12), includes a leaf (42) for mounting discs on opposite sides thereof and a shelf (52) substantially rigidly attached, via attachment plates (51) depending from the shelf, to the jewel box base (16), the leaf (42) being pivotably connected to the shelf (52) via a hinge connection which permits the leaf to pivot thereabout for accessing discs on both sides of the leaf. Flanges (50) cantilevered from the leaf (42) each have an upwardly opening pivot bore (66)for pivotably engaging a pivot pin (54)supported by the shelf (52). Reinforcing plates depending from opposite sides of the shelf are spaced from the shelf attachment plates for rigidly reinforcing the shelf while permitting the shelf attachment plates to flex, as needed, to engage the jewel box base.
摘要翻译：用于将多个盘保持在储存容器内的托盘（14），其理想地是传统的单盘式宝石盒（12），包括用于在相对侧安装盘的叶片（42）和基本上刚性地连接通过从搁架悬挂的附接板（51）到宝石盒基座（16），叶片（42）通过铰链连接件可枢转地连接到搁板（52），该铰链连接件允许叶片在其周围枢转以访问盘叶两边。从叶片（42）悬臂的凸缘（50）各自具有向上开口的枢轴孔（66），用于可枢转地接合由搁架（52）支撑的枢轴销（54）。从搁架的相对侧悬垂的加强板与货架附件板间隔开，以便刚性地加强货架，同时允许货架附件板根据需要弯曲以接合珠宝盒底座。

3. 发明申请

WO2006096545A3 WATERPROOF HYDROTHERAPY LIMB MASSAGER 审中-公开
公开(公告)号：WO2006096545A3
公开(公告)日：2006-09-14
申请号：PCT/US2006/007692
申请日：2006-03-02
申请人： PISANI, Robert, J. , HORTON, James, A.
发明人： PISANI, Robert, J. , HORTON, James, A.
IPC分类号： A61H1/00
摘要： A hydrotherapy massage apparatus for the limbs of a patient having a water-tight chamber and a limb-receiving and surrounding waterproof, flexible sleeve extending longitudinally through an opening in the front wall of the chamber for insertion of the limb to be massaged into the chamber. At least one continuous hollow water head surrounds the sleeve and has opposed, peripherally spaced apart openings facing the sleeve through which water jets may be directed upon peripherally spaced apart portions of the limb within the sleeve.

4. 发明申请

WO2005051330A3 METHOD FOR TREATING HUMAN TUMOR CELLS WITH A NEWCASTLE DISEASE VIRUS STRAIN HAVING A p53 INDEPENDENT ONCOLYTIC EFFECT 审中-公开
公开(公告)号：WO2005051330A3
公开(公告)日：2005-06-09
申请号：PCT/US2004/039853
申请日：2004-11-24
申请人： UNITED CANCER RESEARCH INSTITUTE , CSATARY, Laszlo, K. , SZEBERENYI, Joseph , FABIAN, Zsolt
发明人： CSATARY, Laszlo, K. , SZEBERENYI, Joseph , FABIAN, Zsolt
IPC分类号： C12N7/00
摘要： A method for treating p53-negative human tumor cells to induce apoptotic cell death thereof includes the step of infecting the tumor cells with the Herefordshire strain of Newcastle disease virus. The MOI is in the range of 100/1 to 1/200 cell/infected particle ratio.

5. 发明申请

WO2004070227A2 VIBRATION ABSORBER ASSEMBLY 审中-公开
标题翻译：振动吸收器总成
公开(公告)号：WO2004070227A2
公开(公告)日：2004-08-19
申请号：PCT/US2004/002031
申请日：2004-01-26
申请人： WILLIAMS, Kenneth, A.
发明人： WILLIAMS, Kenneth, A.
IPC分类号： F16F
CPC分类号： F16F15/145 , F16F15/31 , Y10T74/2111 , Y10T74/2128
摘要： A vibration absorber assembly including a disc shaped housing having a central rotational axis and a plurality of radially elongated cavities, and a plurality of movable masses, each movable mass being housed in, and movable within, one of the plurality of radially elongated cavities. The plurality of movable masses are movable in the plurality of radially elongated cavities to absorb torsional vibration, and/or alter moment of inertia of the vibration absorber assembly.
摘要翻译：一种振动吸收器组件，包括具有中心旋转轴线和多个径向细长空腔的盘形壳体，以及多个可移动质量块，每个可移动质量块被容纳在所述多个径向细长空腔中的一个中并可移动。多个可移动质量块可以在多个径向细长的空腔中移动以吸收扭转振动，和/或改变减震器组件的惯性矩。

6. 发明申请

WO2016054174A1 METHOD OF IN VIVO MONITORING OF THE CONDITION OF AN INTERNAL SURGICAL REPAIR 审中-公开
标题翻译：血管内窥镜检查条件监测方法
公开(公告)号：WO2016054174A1
公开(公告)日：2016-04-07
申请号：PCT/US2015/053169
申请日：2015-09-30
申请人： S. JACKSON, INC.
发明人： JACKSON, Janko , JACKSON, Stephen L. , TONEY, Crayton G.
IPC分类号： A61B19/00 , A61L17/06 , A61L17/10
CPC分类号： A61B6/12 , A61B5/055 , A61B5/4851 , A61B5/7246 , A61B6/481 , A61B6/5217 , A61B8/0833 , A61B8/481 , A61B8/5223 , A61B17/06166 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61F2/0063 , A61F2250/0098 , A61L17/04 , A61L17/10 , A61L27/18 , A61L27/50 , A61L27/56 , A61L2400/12 , C08L77/00
摘要： A method of in vivo monitoring the condition of an internal body repair in which a radiopaque repair device has been surgically inserted, including: in vivo sensing of dimensional or chemical characteristics values of said repair device during the post-surgical healing process; comparing the sensed values with a previously developed correlation between said sensed values and the value of said characteristics at which failure occurs of comparable repair devices; wherein said sensed value of said characteristics relative to the repair device's failure value of said characteristics, considered in conjunction with the anticipated time for complete healing of said repair, provides information as to the condition of the repair.
摘要翻译：一种体内监测其中外科手术插入不透射线修复装置的内部身体修复的状况的方法，包括：在手术后愈合过程中体内检测所述修复装置的尺寸或化学特征值; 将感测值与所述感测值之间的先前发展的相关性与可比较的修理装置发生故障的所述特性的值进行比较; 其中所述特征相对于修复装置的所述特性的故障值的所述感测值结合所述修复的完全愈合的预期时间考虑，提供关于修复状况的信息。

7. 发明申请

WO2015179167A1 RADIOPAQUE SUTURE 审中-公开
公开(公告)号：WO2015179167A1
公开(公告)日：2015-11-26
申请号：PCT/US2015/030268
申请日：2015-05-12
申请人： S. JACKSON, INC.
发明人： JACKSON, Janko , JACKSON, Stephen, L. , TONEY, Crayton, G.
IPC分类号： A61B17/06 , A61L17/04 , B29C47/02
CPC分类号： A61B17/06166 , A61B17/06004 , A61B2017/00526 , A61B2017/06019 , A61B2090/3966 , A61L17/00 , A61L17/005 , A61L17/10 , A61L2300/102 , A61L2300/44 , D01D11/06 , D06M15/59 , D06M23/08 , D06M2101/34 , C08L77/00
摘要： A polyamide suture includes an elongate core formed of multiple twisted and beat set filaments formed of a first polyamide material and a sheath forced of a second polyarmde material sorrounding the core along its length, the second polyamide material having dispersed therein non-absorbable radiopaque nanoparticles comprising 15-25% by weight, of the second poiyarnide material. The melting point of the first polyamide material is at least 30° C greater than the melting point of the second polyamide material. The core may also include or be formed of previously extruded bundles of first polyamide filaments overcoated with a second polyamide sheath. The suture is made by coextruding the core arid a molten organic material formed of the second polyamide material and dispersed radiopaque nanoparticles. Desirably, the first polyamide matenal its polyamide 66 and the second polyamide material is polyamide 6.
摘要翻译：聚酰胺缝合线包括由多个由第一聚酰胺材料形成的扭绞和捻合长丝形成的细长芯，以及沿其长度围绕芯沿第二聚甲醛材料强制的护套，第二聚酰胺材料分散有不可吸收的不透射线纳米颗粒，包括 15-25重量％的第二聚亚麻材料。第一聚酰胺材料的熔点比第二聚酰胺材料的熔点高至少30℃。核心还可以包括或由先前挤出的第一聚酰胺长丝束形成，其中第一聚酰胺丝线用第二聚酰胺鞘覆盖。缝合线通过共挤出芯部和由第二聚酰胺材料形成的熔融有机材料和分散的不透射线的纳米颗粒而制成。理想地，第一聚酰胺基聚酰胺66和第二聚酰胺材料是聚酰胺6。

8. 发明申请

WO2005089243A2 ADAPTER FOR DIGITAL MEDIA READER 审中-公开
标题翻译：数位媒体阅读器适配器
公开(公告)号：WO2005089243A2
公开(公告)日：2005-09-29
申请号：PCT/US2005/008294
申请日：2005-03-11
申请人： SCM MICROSYSTEMS (U.S.) INC. , KANGASUNDRAM, Siva, Balan, A. , NEO, Ah, Leen , PISARCZYK, John
发明人： KANGASUNDRAM, Siva, Balan, A. , NEO, Ah, Leen , PISARCZYK, John
IPC分类号： G06K7/06
CPC分类号： G06K7/0047 , H01R31/06
摘要： An adapter for removable insertion into a digital media slot, having the same interface as the adapter, formed in a front panel of a digital media reader, the adapter removably receiving digital media therein instead of directly into the reader, includes a generally rectangular header having a first face defining a plurality of female apertures in a configuration corresponding to the configuration of the reader’s male connector pins and a second face having a plurality of projecting male connector pins in the same configuration as the reader’s male connector pins, guide means corresponding to the reader’s guide structure defining the sides of the header for slidably engaging the guide structure of the reader and a metal plate on the header for discharging electrostatic charge when the adapter is inserted into the reader, the adapter being positioned behind the front panel of the reader when fully inserted into the slot.
摘要翻译：一种用于可拆卸地插入到数字媒体插槽中的适配器，具有与适配器相同的接口，形成在数字媒体读取器的前面板中，适配器可拆卸地在其中可拆卸地接收数字媒体，而不是直接进入读取器，包括大致矩形的头部，第一面，其以对应于读取器的阳连接器针的配置的配置来限定多个阴孔，第二面具有与读取器的阳连接器针相同的配置的多个突出的阳连接器针，对应于读取器的引导结构限定了头部的侧面，用于可滑动地接合读取器的引导结构，并且当适配器被插入到读取器中时，该头部上的金属板用于排放静电电荷，适配器位于读取器的前面板的后面，完全插入插槽。

9. 发明申请

WO2004110906A3 A ROTARY SHEETER HAVING AN IMPROVED VACUUM MEANS FOR CROSS TRIM REMOVAL 审中-公开
公开(公告)号：WO2004110906A3
公开(公告)日：2004-12-23
申请号：PCT/US2004/017628
申请日：2004-06-03
申请人： ADVANCE GRAPHICS EQUIPMENT OF YORK, INC. , SNYDER, Dennis, L.
发明人： SNYDER, Dennis, L.
IPC分类号： B26D7/06
摘要： Apparatus for continuously cutting a web and removing trim strips therefrom, including a pair of circumferentially spaced knives supported on a cutting shaft, the shaft being rotationally mounted for cutting, in a cutting area, the web transverse to its direction of movement for forming trim strips, a cylinder mounted along the underside of the web for rotation about an axis which is generally perpendicular to the direction of the moving web, the cylinder having a hollow bore communicating with a low pressure source and an opening formed in the surface of the cylinder communicating with the bore for providing low pressure at the opening, the cylinder being rotated at a predetermined speed such that the opening is positioned in the cutting area immediately downstream of the knives each time a trim strip is cut from the web and the opening is rotated away from the cutting area immediately thereafter.

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