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1. 发明申请

WO2009114925A1 ELECTROCHEMICAL PROCESS FOR THE RECOVERY OF METALLIC IRON AND CHLORINE VALUES FROM IRON-RICH METAL CHLORIDE WASTES 审中-公开
标题翻译：从金属氯化物废物中回收金属铁和氯离子值的电化学工艺
公开(公告)号：WO2009114925A1
公开(公告)日：2009-09-24
申请号：PCT/CA2008/000544
申请日：2008-03-20
申请人： QIT-FER & TITANE INC. , CARDARELLI, François , LEFEBVRE, Sylvain , TOUSIGNANT, Claude , HUDON, Guillaume
发明人： CARDARELLI, François , LEFEBVRE, Sylvain , TOUSIGNANT, Claude , HUDON, Guillaume
IPC分类号： C25C1/06 , C22B3/20 , C25B1/26 , C25B11/04 , C25C7/02
CPC分类号： C25C1/06 , C22B3/045 , C22B7/007 , C25B1/26 , C25B11/04 , C25C7/02 , Y02P10/234
摘要： An electrochemical process for the concurrent recovery of iron metal and chlorine gas from an iron-rich metal chloride solution, comprising electrolysing the iron-rich metal chloride solution in an electrolyser comprising a cathodic compartment equipped with a cathode having a hydrogen overpotential higher than that of iron and containing a catholyte having a pH below about 2, an anodic compartment equipped with an anode and containing an anolyte, and a separator allowing for anion passage, the electrolysing step comprising circulating the iron-rich metal chloride solution in a non-anodic compartment of the electrolyser, thereby causing iron to be electrodeposited at the cathode and chlorine gas to evolve at the anode, and leaving an iron-depleted solution, which is recirculated, at least in part, to the iron-rich metal chloride solution. The iron-rich metal chloride solution may originate from carbo-chlorination wastes, spent acid leaching liquors or pickling liquors.
摘要翻译：一种用于从富铁金属氯化物溶液中同时回收铁金属和氯气的电化学方法，包括在电解槽中电解富铁金属氯化物溶液，该电解槽包括阴极室，该阴极室装备有具有高于铁，并含有pH值低于约2的阴极电解液，装有阳极并含有阳极电解液的阳极室和允许阴离子通过的隔膜，所述电解步骤包括将富铁金属氯化物溶液循环在非阳极室的电解液，从而使铁电解沉积在阴极，氯气在阳极放出，留下一种贫铁溶液，其至少部分地再循环到富铁金属氯化物溶液中。富含铁的金属氯化物溶液可来自碳氯化废物，废酸浸液或酸洗液。

2. 发明申请

WO2009103166A1 TREATMENT OF NEURAL DISEASES OR CONDITIONS 审中-公开
标题翻译：治疗神经疾病或病症
公开(公告)号：WO2009103166A1
公开(公告)日：2009-08-27
申请号：PCT/CA2009/000208
申请日：2009-02-20
申请人： THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY , RADZIOCH, Danuta , DAVID, Samuel , LOPEZ-VALES, Ruben , SKINNER, Thomas
发明人： RADZIOCH, Danuta , DAVID, Samuel , LOPEZ-VALES, Ruben , SKINNER, Thomas
IPC分类号： A61K31/167 , A61K45/00 , A61K47/48 , A61P25/28
CPC分类号： A61K31/167 , A61K45/06 , A61K49/0008
摘要： Compounds, methods, uses, compositions, kits and packages for the prevention and/or treatment of neural injury or a neurodegenerative disease, based on the use of a retinoic acid derivative, such as fenretinide, and/or analogs, derivatives, prodrugs, precursors thereof, and/or salts thereof, are described.
摘要翻译：基于视黄酸衍生物如芬维A胺和/或类似物，衍生物，前药，前体的用途，用于预防和/或治疗神经损伤或神经变性疾病的化合物，方法，用途，组合物，试剂盒和包装和/或其盐。

3. 发明申请

WO2009015487A1 CONNECTOR WITH INSULATION PIERCING CONTACT 审中-公开
标题翻译：带绝缘接头的连接器
公开(公告)号：WO2009015487A1
公开(公告)日：2009-02-05
申请号：PCT/CA2008/001418
申请日：2008-08-01
申请人： BELDEN CDT CANADA INC. , MILETTE, Luc , BEAUREGARD, François , DEMERS, Yannick , SIEV, Virak , ST-LOUIS, Patrick
发明人： MILETTE, Luc , BEAUREGARD, François , DEMERS, Yannick , SIEV, Virak , ST-LOUIS, Patrick
IPC分类号： H01R4/24 , H01R13/512 , H01R24/04
CPC分类号： H01R24/64 , H01R4/2404 , H01R13/6463
摘要： There is disclosed a connector and method for terminating a cable comprised twisted pairs of conductors. One major drawback of the prior art is that, as the point of insertion of individual conductors into the connectors is arranged along a parallel line, unwanted cross-talk and the like may arise, thus reducing the connectors' performance, especially at high frequencies. Moreover, the separation between the conductors of a twisted pair is not rigorously maintained. In one aspect of the invention the connector (10) comprises a wire lead guide (16) for arranging the twisted pairs of conductors (70) and a plurality of piercing contacts (40) which interconnect with respective ones of the twisted pairs of conductors when the wire guide is secured to the module. In a further aspect of the invention the wire lead guide is secured to the module. In a further aspect of the invention the wire lead guide (16) ensures that the spacing between the conductors of a particular twisted pair (70) is maintained, thereby improving the performance of the subsequent assembly.
摘要翻译：公开了一种用于端接包括双绞导线的电缆的连接器和方法。现有技术的一个主要缺点是，由于单个导体插入连接器的点沿着平行线布置，所以可能会出现不想要的串扰等，从而降低连接器的性能，特别是在高频下。此外，双绞线的导体之间的分离不是严格保持的。在本发明的一个方面，连接器（10）包括用于布置双绞线导体（70）的导线引导件（16）和与导体的双绞线互连的多个穿孔触头（40）电线导轨固定在模块上。在本发明的另一方面，导线引导件固定到模块。在本发明的另一方面，导线引导件（16）确保了特定双绞线（70）的导体之间的间隔被保持，由此提高随后组件的性能。

4. 发明申请

WO2009003284A1 NOVEL PEPTIDES, USE THEREOF IN COSMETIC AND COSMECEUTIC APPLICATIONS, AND COMPOSITIONS COMPRISING SAME 审中-公开
标题翻译：新型肽，其在化妆品和成膜应用中的应用，以及包含其的组合物
公开(公告)号：WO2009003284A1
公开(公告)日：2009-01-08
申请号：PCT/CA2008/001227
申请日：2008-06-30
申请人： LES BIOTECHNOLOGIES OCEANOVA INC. , HOCQUAUX, Michel , LOING, Estelle , BEDOS, Philippe
发明人： HOCQUAUX, Michel , LOING, Estelle , BEDOS, Philippe
IPC分类号： C07K7/06 , A61K38/06 , A61K38/07 , A61K38/08 , A61K8/64 , A61P17/00 , A61P29/00 , A61Q19/10 , C07K5/083 , C07K5/11 , C07K5/117
CPC分类号： C07K5/1019 , A61K8/64 , A61K38/00 , A61Q17/04 , A61Q19/08 , C07K5/0806 , Y02P20/55
摘要： A peptide of formula I (SEQ ID NO: 1): Lip-A-Gly-His-B-R (I) wherein: Lip is a lipoyl residue of R or S configuration; A is absent or is a lysine residue of configuration L or D; GIy is a glycine residue; His is a histidine residue of configuration L or D; B is a lysine residue of configuration L or D, or a lysine residue of configuration L or D in which the NH2 group of the side chain comprises a modification, wherein said modification is (i) a replacement with a hydrogen or (ii) a modification with a protecting group selected from the group consisting of acetyl, benzoyl, tosyl, sulfonyl benzene, benzyloxycarbonyle and palmitoyl; wherein R is O(Z) or N(Z')(Z"), and wherein Z, Z' and Z" are independently of each other a hydrogen or a protecting group selected from the group consisting of methyl, ethyl, propyl, phenyl, hexyl, decyl and hexadecyl, or a racemate, an enantiomer or a diastereomer thereof, or a mixture thereof, or a salt thereof. A peptide of formula Il (SEQ ID NO: 2): Lip-A-His-B-C-Trp-R (II) wherein: Lip is a lipoyl residue of configuration R or S; His is a histidine residue of configuration L; Trp is a tryptophane residue of configuration L; A is absent, is an amino acid residue of configuration L or D selected from the group consisting of a lysine residue, an alanine residue, a glutamic acid residue and a glycine residue, or is a spacer of formula : NH-(CH2)n-CO- wherein n is an integer comprised between 2 and 14; B is an aromatic amino acid residue of configuration D selected from the group consisting of a phenylalanine residue, a homophenylalanine residue, a tryptophane residue, a β-(1-Naphthyl)-alanine residue, a β-(2-Naphthyl)-alanine residue and a phenylglycine residue; C is a basic amino acid residue of configuration L selected from the group consisting of an arginine residue, a lysine residue, an ornithine residue and a homoarginine residue; wherein R is O(Z) or N(Z')(Z"), and wherein Z, Z' and Z" are independently of each other a hydrogen or a protecting group selected from the group consisting of methyl, ethyl, propyl, phenyl, hexyl, decyl and hexadecyl, or a racemate, an enantiomer or a diastereomer thereof, or a mixture thereof, or a salt thereof.
摘要翻译：式I的肽（SEQ ID NO：1）：Lip-A-Gly-His-B-R（I）其中：Lip是R或S构型的脂酰基残基; A不存在或是L或D构型的赖氨酸残基; Gly是甘氨酸残基; His是构型L或D的组氨酸残基; B是构型L或D的赖氨酸残基或其中侧链的NH 2基团包含修饰的构型L或D的赖氨酸残基，其中所述修饰是（i）用氢取代或（ii）用选自乙酰基，苯甲酰基，甲苯磺酰基，磺酰基苯，苄氧基羰基和棕榈酰基的保护基改性; 其中R是O（Z）或N（Z'）（Z“），并且其中Z，Z'和Z”彼此独立地是氢或选自甲基，乙基，丙基，苯基，己基，癸基和十六烷基，或其外消旋物，对映异构体或非对映体，或其混合物，或其盐。式II（SEQ ID NO：2）的肽：Lip-A-His-B-C-Trp-R（II）其中：Lip是R或S构型的脂酰基残基; His是构型L的组氨酸残基; Trp是配置L的色氨酸残基; A不存在，是选自赖氨酸残基，丙氨酸残基，谷氨酸残基和甘氨酸残基的构型L或D的氨基酸残基，或者是下式的间隔基：NH-（CH 2）n -CO-，其中n是2至14之间的整数; B是配置D的芳族氨基酸残基，选自苯丙氨酸残基，高苯丙氨酸残基，色氨酸残基，β-（1-萘基） - 丙氨酸残基，β-（2-萘基） - 丙氨酸残基和苯基甘氨酸残基; C是选自精氨酸残基，赖氨酸残基，鸟氨酸残基和高精氨酸残基的构型L的碱性氨基酸残基; 其中R是O（Z）或N（Z'）（Z“），并且其中Z，Z'和Z”彼此独立地是氢或选自甲基，乙基，丙基，苯基，己基，癸基和十六烷基，或其外消旋物，对映异构体或非对映体，或其混合物，或其盐。

5. 发明申请

WO2008154752A1 HYBRID ELECTRIC PROPULSION SYSTEM 审中-公开
标题翻译：混合电动推进系统
公开(公告)号：WO2008154752A1
公开(公告)日：2008-12-24
申请号：PCT/CA2008/001223
申请日：2008-06-23
申请人： DESHAIES, Raymond , CHARTRAND, Marcel
发明人： DESHAIES, Raymond , CHARTRAND, Marcel
IPC分类号： B60K6/30 , F16F15/31
CPC分类号： B60W20/00 , B60K1/02 , B60K6/105 , B60K6/26 , B60K6/38 , B60K6/46 , B60L11/123 , B60L11/16 , B60L11/1816 , B60L2270/44 , B60W10/06 , B60W10/08 , B60W10/24 , Y02T10/6204 , Y02T10/6217 , Y02T10/6269 , Y02T10/6282 , Y02T10/6286 , Y02T10/7005 , Y02T10/7027 , Y02T10/7033 , Y02T10/7072 , Y02T10/7077 , Y02T90/14 , Y10T74/2119
摘要： A hybrid electric propulsion system for a vehicle. The system includes an internal combustion engine (12); a flywheel (14) operatively connected to the engine (12), the flywheel (14) having a horizontal rotation axis parallel to a rotation axis of the wheels of the vehicle, the flywheel (14) having a main disk being rotatable in an opposite direction (R FES ) with respect to a rotation of the wheels (R T ) of the vehicle when the vehicle is travelling forward so as to inhibit a rollover effect of the vehicle when the vehicle is turning; an electric generator (18) operatively connected to the flywheel (14); an electric motor (22) operatively connected to the electric generator (18); and a controller for controlling operation of the engine (12), the flywheel (14), the electric generator (18) and the electric motor (22).
摘要翻译：一种用于车辆的混合动力电动推进系统。该系统包括内燃机（12）; 飞轮（14），其可操作地连接到所述发动机（12），所述飞轮（14）具有平行于所述车辆的车轮的旋转轴线的水平旋转轴线，所述飞轮（14）具有主盘，当车辆向前行进时相对于车辆的车轮（RT）的旋转方向（RFES），以便当车辆转弯时阻止车辆的翻车效果; 可操作地连接到飞轮（14）的发电机（18）; 可操作地连接到所述发电机（18）的电动机（22）; 以及用于控制发动机（12），飞轮（14），发电机（18）和电动机（22）的操作的控制器。

6. 发明申请

WO2008154739A1 CO-CATALYSTS FOR HYBRID CATALYSTS, HYBRID CATALYSTS COMPRISING SAME, MONOCOMPONENT CATALYSTS, METHODS OF MANUFACTURE AND USES THEREOF 审中-公开
标题翻译：用于混合催化剂的CO催化剂，包含其的混合催化剂，单组分催化剂，其制备方法及其用途
公开(公告)号：WO2008154739A1
公开(公告)日：2008-12-24
申请号：PCT/CA2008/001163
申请日：2008-06-17
申请人： VALORBEC Societe en Commandite , LE VAN MAO, Raymond
发明人： LE VAN MAO, Raymond
IPC分类号： B01J23/883 , B01J21/02 , B01J37/04 , C10G11/04
CPC分类号： B01J23/83 , B01J21/04 , B01J23/10 , B01J23/28 , B01J23/755 , B01J23/8871 , B01J23/8896 , B01J23/892 , B01J29/40 , B01J29/46 , B01J29/48 , B01J35/0006 , B01J35/002 , B01J35/1019 , B01J37/0009 , B01J37/0201 , B01J37/033 , B01J37/04 , B01J2229/42 , C10G11/05
摘要： Co-catalysts comprising yttria-stabilized aluminum oxide having nickel oxide loaded thereon, their uses and methods of preparing are described. Also, hybrid catalysts comprising these co-catalysts along with main catalyst components, and their uses and methods of preparing are described. Monocomponent catalysts having nickel oxide loaded thereon, their uses and methods of preparing are also described.
摘要翻译：描述了包含其中负载有氧化镍的氧化钇稳定的氧化铝的助催化剂，其用途和制备方法。此外，描述了包含这些助催化剂以及主要催化剂组分的混合催化剂及其用途和制备方法。还描述了其中负载有氧化镍的单组分催化剂，其用途和制备方法。

7. 发明申请

WO2008138131A4 BONE TARGETED ALKALINE PHOSPHATASE, KITS AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2008138131A4
公开(公告)日：2008-11-20
申请号：PCT/CA2008/000923
申请日：2008-05-12
申请人： ENOBIA PHARMA INC. , CRINE, Philippe , BOILEAU, Guy , LOISEL, Thomas, P. , LEMIRE, Isabelle , LEONARD, Pierre , HEFT, Robert , LANDY, Hal
发明人： CRINE, Philippe , BOILEAU, Guy , LOISEL, Thomas, P. , LEMIRE, Isabelle , LEONARD, Pierre , HEFT, Robert , LANDY, Hal
IPC分类号： C12N15/55 , A61K38/46 , A61P19/08 , C12N15/85 , C12N5/10 , C12N9/16
摘要： A bone targeted alkaline phosphatase comprising a polypeptide having the structure : Z-sALP-Y-spacer-X-W n -V, wherein sALP is the extracellular domain of the alkaline phosphatase; wherein V is absent or is an amino acid sequence of at least one amino acid; X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and W n is a polyaspartate or a polyglutamate wherein n = 10 to 16. Kits and methods of use thereof.

8. 发明申请

WO2008131547A1 "TRIAZINE DERIVATIVES, COMPOSITIONS CONTAINING SUCH DERIVATIVES, AND METHODS OF TREATMENT OF CANCER AND AUTOIMMUNE DISEASES USING SUCH DERIVATIVES" 审中-公开
标题翻译： “TRIAZINE衍生物，含有这些衍生物的组合物，以及使用这种衍生物治疗癌症和自身免疫疾病的方法”
公开(公告)号：WO2008131547A1
公开(公告)日：2008-11-06
申请号：PCT/CA2008/000796
申请日：2008-04-25
申请人： PROMETIC BIOSCIENCES INC. , ZACHARIE, Boulos , PENNEY, Christopher , GAGNON, Lyne , GROUIX, Brigitte , GEERTS, Lilianne , ABBOTT, Shaun, D.
发明人： ZACHARIE, Boulos , PENNEY, Christopher , GAGNON, Lyne , GROUIX, Brigitte , GEERTS, Lilianne , ABBOTT, Shaun, D.
IPC分类号： C07D251/70 , A61K31/53 , A61P35/00 , A61P37/00 , C07D251/18
CPC分类号： C07D251/18 , C07D251/70
摘要： We describe compounds of the following general formula (I): wherein X is fluorine or chlorine; Y is oxygen, sulfur, or an amino group; R is an amino, hydroxyl, sulfonamide, or carboxamide group or an N-monomethyl or N-dimethyl analog thereof; m is an integer from 2 to 6, and n is an integer from 0 to 2. The compounds may be used for treating certain cancers and autoimmune diseases.
摘要翻译：我们描述下列通式（I）的化合物：其中X是氟或氯; Y是氧，硫或氨基; R是氨基，羟基，磺酰胺或甲酰胺基团或其N-甲基或N-二甲基类似物; m为2〜6的整数，n为0〜2的整数。该化合物可用于治疗某些癌症和自身免疫性疾病。

9. 发明申请

WO2008128334A1 WEAR-RESISTANT CASTINGS AND METHOD OF FABRICATION THEREOF 审中-公开
标题翻译：耐磨铸件及其制造方法
公开(公告)号：WO2008128334A1
公开(公告)日：2008-10-30
申请号：PCT/CA2008/000720
申请日：2008-04-18
申请人： IGRAM TECHNOLOGIES INC. , TSYPINE, Igor , PERLIN, Rafael
发明人： TSYPINE, Igor , PERLIN, Rafael
IPC分类号： B22D19/00 , B22D19/16 , B22D25/06 , C22C37/06 , C22C37/10
CPC分类号： B22D19/00 , B22D25/06 , C22C37/06 , C22C37/10 , Y10T428/12389 , Y10T428/12493 , Y10T428/12951 , Y10T428/12972
摘要： A wear resistant casting and method of fabrication thereof, the casting comprising inserts embedded in a matrix; each insert having a form such that a ratio A/B in any mutually perpendicular section that passes through the centre of mass of the insert is comprised between 0,4 and 2,5, and a distance C between two insert is at least two times smaller that a width thereof; the inserts forming at least one grid.
摘要翻译：一种耐磨铸件及其制造方法，所述铸件包括嵌入基体中的嵌入件; 每个插入件具有使得穿过插入件的质心的任何相互垂直的部分中的比率A / B在0.4和2.5之间的形式，并且两个插入件之间的距离C是至少两倍小于其宽度; 所述插入件形成至少一个栅格。

10. 发明申请

WO2008122118A1 PHARMACEUTICAL FORMULATIONS OF GHRH MOLECULES 审中-公开
标题翻译： GHRH分子的药物制剂
公开(公告)号：WO2008122118A1
公开(公告)日：2008-10-16
申请号：PCT/CA2008/000637
申请日：2008-04-04
申请人： THERATECHNOLOGIES INC. , LOUGHREY, Helen , CHANG, Byeong
发明人： LOUGHREY, Helen , CHANG, Byeong
IPC分类号： A61K38/25 , A61K9/08 , A61K9/19
CPC分类号： A61K38/25 , A61K9/0019 , A61K9/19
摘要： Stabilized solid and liquid pharmaceutical formulations comprising a GHRH molecules as active ingredient, and more particularly GHRH analogs including [trans-3-hexenoyl]hGHRH (1-44) amide, are disclosed. The formulation comprises an anionic surfactant and a non-reducing sugar, and has a pH of about 4.0 to about 7.5. Also disclosed is the use of the formulation for the treatment of various conditions, methods of preparing the formulation, as well as kits containing it.
摘要翻译：公开了包含GHRH分子作为活性成分的稳定的固体和液体药物制剂，更具体地，包括[反式-3-己烯酰基] hGHRH（1-44）酰胺）的GHRH类似物。制剂包含阴离子表面活性剂和非还原糖，并且具有约4.0至约7.5的pH。还公开了用于治疗各种病症的制剂的用途，制备制剂的方法，以及含有它的试剂盒。

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