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81. 发明申请

WO02000278A2 METHOD AND APPARATUS FOR TREATING ISCHEMIC TISSUE 审中-公开
标题翻译：用于治疗缺血性织物的方法和装置
公开(公告)号：WO02000278A2
公开(公告)日：2002-01-03
申请号：PCT/US2001/041149
申请日：2001-06-26
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32 , A61B18/14 , A61B18/24 , A61B19/00 , A61M5/32 , A61M25/00 , A61M17/00
CPC分类号： A61B17/3207 , A61B17/3203 , A61B17/320758 , A61B18/1477 , A61B18/24 , A61B2017/00247 , A61B2017/003 , A61B2017/22077 , A61B2018/00392 , A61B2018/1425 , A61B2090/395 , A61M5/3287 , A61M2025/0085
摘要： This invention described herein provides for methods and devices for treating tissues, and in particular, ischemic heart tissue. Preferred devices includes tools integrating both injury and treatment effectors in a single unit. An optional third effector provides an effector for marking locations on a tissue surface that have been visited by the device. Methods are provided in which a target tissue is identified, injury sites are created at known locations, and therapeutic-substance is infused at known locations different than the injury sites.
摘要翻译：本发明涉及用于治疗组织，特别是心脏局部缺血组织的方法和装置。优选地，这种类型的装置包括其中伤口和治疗效应器被集成到一个单元中的器械。可选地，使用第三效应器在已经被设备检查的织物的表面上制造位置标记。本发明还提供了用于识别目标组织，在已知位置处产生损伤部位以及在与伤口部位不同的已知位置处注射治疗物质的方法。

82. 发明申请

WO01080723A2 ABLATION OF RECTAL AND OTHER INTERNAL BODY STRUCTURES 审中-公开
标题翻译：排除其他内部身体结构
公开(公告)号：WO01080723A2
公开(公告)日：2001-11-01
申请号：PCT/US2001/013144
申请日：2001-04-24
IPC分类号： A61B17/00 , A61B17/22 , A61B17/24 , A61B17/30 , A61B18/00 , A61B18/04 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/22 , A61B19/00 , A61M1/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61B
CPC分类号： A61B18/1485 , A61B17/24 , A61B18/04 , A61B18/1402 , A61B18/1477 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B18/22 , A61B90/361 , A61B2017/00026 , A61B2017/00084 , A61B2017/00296 , A61B2017/22067 , A61B2017/22077 , A61B2017/306 , A61B2018/00011 , A61B2018/00023 , A61B2018/00065 , A61B2018/00101 , A61B2018/00196 , A61B2018/00214 , A61B2018/00261 , A61B2018/00285 , A61B2018/00327 , A61B2018/00547 , A61B2018/00553 , A61B2018/00577 , A61B2018/00636 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00744 , A61B2018/00761 , A61B2018/00773 , A61B2018/00791 , A61B2018/00875 , A61B2018/00886 , A61B2018/00898 , A61B2018/00982 , A61B2018/1425 , A61B2090/3782 , A61B2218/003 , A61M2025/0096 , A61N1/06 , A61N1/403
摘要： An apparatus and system for ablation of body structure or tissue in the region of the rectum. A catheter (120) is inserted into the rectum, and an electrode (113) is disposed thereon for emitting energy. The environment for an ablation region is isolated or otherwise controlled by blocking gas or fluid using a pair of inflatable balloons (116) at upstream and downstream locations. Inflatable balloons (116) also serve to anchor the catheter in place. A plurality of electrodes (113) are disposed on the catheter and at least one electrode is selected and advanced out of the catheter to penetrate tissue. The electrodes are coupled to sensors which are used by feedback to control the delivery of energy for ablation or fluids for cooling or hydration.
摘要翻译：用于直肠区域的身体结构或组织消融的装置和系统。将导管（120）插入到直肠中，并且在其上设置用于发射能量的电极（113）。用于消融区域的环境是通过在上游和下游位置处使用一对可充气气囊（116）阻挡气体或流体来隔离或以其他方式控制的。充气气球（116）也用于将导管固定到位。多个电极（113）设置在导管上，并且至少一个电极被选择并从导管中推出以穿透组织。电极耦合到传感器，传感器通过反馈来控制用于消融的能量的输送或用于冷却或水合的流体。

83. 发明申请

WO01070133A2 METHOD AND SYSTEM FOR BYPASSING AN ARTERY BLOCK 审中-公开
标题翻译：用于排除空气块的方法和系统
公开(公告)号：WO01070133A2
公开(公告)日：2001-09-27
申请号：PCT/EP2001/003104
申请日：2001-03-19
IPC分类号： G01R33/28 , A61B5/055 , A61B6/12 , A61B8/12 , A61B17/00 , A61B17/22 , A61B19/00 , A61F2/06 , A61F2/07 , A61B17/32 , A61M25/06
CPC分类号： A61B17/3207 , A61B2017/00252 , A61B2017/00349 , A61B2017/00455 , A61B2017/22044 , A61B2017/22077 , A61B2017/22095 , A61B2090/378 , A61F2/064 , A61F2/07 , A61M2025/0096
摘要： A catheter system for use in bypassing a blocking (3) in an artery (1) comprises four components. These components are an arterial catheter, an intravenous ultrasound catheter, a guide-wire system, and finally a covered stent (4) used as graft. The bypassing of the blocking (3) in the artery (1) which extends along a vein (2) comprises the steps of forming a first connection (6) between said artery (1) and said vein (2) proximal to the blocking (3) in the artery (1), forming a second connection (7) between said artery (1) and said vein (2) distal to the blocking (3) in the artery (1), introducing a covered stent (4) through said artery (1) proximal to the blocking (3) therein, through said first connection (6) into said vein (2), via said vein (2) to and through said second connection (7), and into said artery (1) distal to the blocking (3) therein, such that a proximal end (9) of the covered stent (4) is positioned in the artery (1) proximal to the blocking (3) therein and a distal end (10) of the covered stent (4) is positioned in the artery (3) distal to the blocking (3) therein, and fixing the proximal and distal ends (9, 10) of the covered stent (4) within the artery (1).
摘要翻译：用于绕过动脉（1）中的阻塞（3）的导管系统包括四个部件。这些组件是动脉导管，静脉内超声导管，导丝系统，最后是用作移植物的覆盖支架（4）。沿着静脉（2）延伸的动脉（1）中的阻塞（3）的旁路包括以下步骤：在所述动脉（1）和靠近阻塞的所述静脉（2）之间形成第一连接（6） 3）在动脉（1）中形成在动脉（1）之间的所述动脉（1）和远离阻塞（3）的所述静脉（2）之间的第二连接（7），将覆盖的支架（4）所述动脉（1）通过所述第一连接件（6）通过所述静脉（2）经过所述第二连接件（7）并通过所述第二连接件（7），并通过所述第一连接件（6）进入所述动脉），使得所覆盖的支架（4）的近端（9）位于其中靠近所述阻塞（3）的动脉（1）中，并且所述远端（10）位于所述阻塞被覆盖的支架（4）位于远离其上的阻塞（3）的动脉（3）中，并且将被覆盖的支架（4）的近端和远端（9,10）固定在动脉（1）内。

84. 发明申请

WO01037767A1 DEVICE FOR IMPROVING THE AQUEOUS HUMOUR OUTFLOW IN THE EYE OF A LIVING THING 审中-公开
标题翻译：设备技术改进室排水在活眼
公开(公告)号：WO01037767A1
公开(公告)日：2001-05-31
申请号：PCT/CH2000/000627
申请日：2000-11-23
IPC分类号： A61B1/00 , A61B1/018 , A61B1/04 , A61B17/22 , A61B17/32 , A61B17/34 , A61B19/00 , A61F9/007
CPC分类号： A61F9/00781 , A61B1/00193 , A61B1/018 , A61B1/042 , A61B17/32002 , A61B17/3201 , A61B2017/22077 , A61B2017/305 , A61B2017/3445 , A61B2090/3614
摘要： The invention relates to a device for performing ophthalmologic interventions, in particular to improve the aqueous humour outflow in the eye of a living thing. Said device (200) comprises an endoscope (25) which is linked to a monitor (20) and provided with a probe (30) that comprises at least one first channel positioned in an axial direction and equipped with optical elements for focusing and transmitting images of the observation area in the eye (10). A working channel is also provided in the small tubular probe (30), in which a surgical instrument which is displaceable in an axial direction, can operate upon the trabecular tissue (9) in a vibrating and/or oscillating manner, to create a passage which connects the anterior chamber (V) to Schlemm's canal (8).
摘要翻译：它提出了一种用于执行手术的眼科，尤其是改善房水在活体的眼睛的流出的装置。所述装置（200）包括在通信内窥镜监视器屏幕（20），（25），其具有布置在其上的探针（30）包括在轴向方向上的至少一个取向，并且具有用于聚焦和用于在眼睛中发送所述观察区域的图像的光学元件（10）形成的第一通道上。在管状探针（30）还包括设置有所述施累姆氏管（8）的通路通道中的工作通道，其中在沿轴向移位的振动的外科手术工具和/或摆动与小梁网连接（9），以形成前腔室（V）接合。

85. 发明申请

WO01005450A1 MULTI-CHANNELED INSERTION SYSTEM FOR SIMULTANEOUS DELIVERY OF BIOLOGICALLY ACTIVE ELEMENTS TO MULTIPLE ORGAN SITES 审中-公开
标题翻译：多通道插入系统，用于同时向多个有机网站提供生物活性元素
公开(公告)号：WO01005450A1
公开(公告)日：2001-01-25
申请号：PCT/US2000/019219
申请日：2000-07-14
IPC分类号： A61B17/00 , A61B17/22 , A61B17/34 , A61M25/00 , A61M5/00
CPC分类号： A61B17/3468 , A61B17/3417 , A61B2017/00274 , A61B2017/22077 , A61B2017/3445 , A61B2018/00547 , A61M2025/0034 , A61M2025/0036 , A61M2025/004 , A61M2025/0096
摘要： A multi-channeled insertion system (10) includes a longitudinal structure (12) having a proximal end, a distal end, and an axis extending between the proximal end and the distal end. The multi-channeled insertion system further includes a plurality of channels (18), with each of the plurality of channels beginning at an entry port, extending distally therefrom and terminating at an exit port which is disposed distally of the entry port. Each of the plurality of channels being is constructed to accommodate a tubular structure therethrough, wherein the tubular structures exit the exit ports at different angles relative to one another.
摘要翻译：多通道插入系统（10）包括具有近端，远端以及在近端和远端之间延伸的轴线的纵向结构（12）。多通道插入系统还包括多个通道（18），其中多个通道中的每一个通道从入口端口开始，从入口端口向远端延伸并且终止于远离入口的出口端口。多个通道中的每一个被构造成容纳通过其中的管状结构，其中管状结构相对于彼此以不同的角度离开出口。

86. 发明申请

WO01005306A1 APPARATUS AND METHOD FOR ABLATING TISSUE 审中-公开
标题翻译：装置和方法，用于剥离组织
公开(公告)号：WO01005306A1
公开(公告)日：2001-01-25
申请号：PCT/US2000/019614
申请日：2000-07-18
IPC分类号： A61B5/042 , A61B8/00 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/00 , A61B18/02 , A61B18/04 , A61B18/14 , A61B18/18 , A61B19/00 , A61N1/06 , A61N1/362 , A61N7/00 , A61N7/02
CPC分类号： A61B17/22012 , A61B5/0422 , A61B17/2202 , A61B18/00 , A61B18/02 , A61B18/1402 , A61B18/148 , A61B18/1482 , A61B18/1492 , A61B34/20 , A61B2017/00039 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22077 , A61B2017/3419 , A61B2018/00023 , A61B2018/0016 , A61B2018/00232 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/00839 , A61B2018/142 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/395 , A61B2218/002 , A61B2218/007 , A61N1/06 , A61N1/362 , A61N7/02 , A61N2007/0065 , A61N2007/0078 , A61N2007/027
摘要： A control system (334) alters one or more characteristics of an ablating element (306) to ablate tissue. In one aspect, the control system (334) delivers energy nearer to the surface of the tissue by changing the frequency or power. In another aspect, the ablating element (306) delivers focused ultrasound which is focused in at least one dimension. The ablating device (306) may also have a number of ablating elements with different characteristics such as focal length.
摘要翻译：控制系统（334）改变烧蚀元件（306）的一个或多个特征以消融组织。在一个方面，控制系统（334）通过改变频率或功率来传递更接近组织表面的能量。在另一方面，烧蚀元件（306）传送聚焦在至少一个维度上的聚焦超声波。烧蚀装置（306）还可以具有多个具有不同特征的烧焦元件，例如焦距。

87. 发明申请

WO00027312A1 MINIMALLY INVASIVE REVASCULARIZATION APPARATUS AND METHODS 审中-公开
标题翻译：最小的入侵重建装置和方法
公开(公告)号：WO00027312A1
公开(公告)日：2000-05-18
申请号：PCT/US1999/026196
申请日：1999-11-05
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/122 , A61B17/22 , A61B17/32 , A61B17/34 , A61B19/00 , A61F2/06 , A61M25/00 , A61M25/01
CPC分类号： A61F2/064 , A61B17/0644 , A61B17/11 , A61B17/122 , A61B17/221 , A61B17/32053 , A61B17/3207 , A61B17/3478 , A61B90/39 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2017/22038 , A61B2017/22077 , A61B2017/2212 , A61B2017/2217 , A61M25/0068 , A61M25/0074 , A61M25/0082 , A61M25/0108 , A61M25/10 , A61M2025/0081 , A61M2025/1079
摘要： A bypass graft conduit (200) is installed in the circulatory system of a patient using apparatus which facilitates performing most or all of the necessary work intraluminally (i.e., via lumens of the patient's circulatory system). A guide structure such as a wire (600) is installed in the patient via circulatory system lumens (210) so that a portion (220) of the guide structure extends along the desired path of the bypass conduit, which bypass conduit path is outside the circulatory system as it exists prior to installation of the bypass graft. The bypass graft is then introduced into the patient along the guide structure and connected at each of its ends to the circulatory system using connectors (60) that form fluid-tight annular openings from the bypass graft lumen into the adjacent circulatory system lumens. The guide structure is then pulled out of the patient.
摘要翻译：旁路移植导管（200）安装在患者的循环系统中，该装置有利于进行大部分或全部必要的工作（即通过患者的循环系统的流明）。通过循环系统管腔（210）将诸如电线（600）的引导结构安装在患者体内，使得引导结构的一部分（220）沿着旁路导管的期望路径延伸，旁路导管路径在循环系统在安装旁路移植物之前就存在。然后将旁路移植物沿着引导结构引入患者体内，并使用连接器（60）将其每个端部连接到循环系统，所述连接器（60）从旁路移植物腔形成流体密封的环形开口进入相邻的循环系统腔。然后将引导结构从病人身上拉出。

88. 发明申请

WO00018323A2 METHODS AND APPARATUS FOR CROSSING VASCULAR OCCLUSIONS 审中-公开
标题翻译：用于穿越血管闭塞的方法和设备
公开(公告)号：WO00018323A2
公开(公告)日：2000-04-06
申请号：PCT/US1999/019831
申请日：1999-08-27
IPC分类号： A61M25/00 , A61B17/00 , A61B17/22 , A61B19/00 , A61M25/01 , A61M25/08 , A61M25/09 , A61F2/06
CPC分类号： A61B17/3207 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22044 , A61B2017/22077 , A61B2017/22095 , A61B2018/00392 , A61B2090/3925 , A61M25/01 , A61M2025/018 , A61M2025/0197
摘要： Methods and apparatus for crossing totally to substantially occluded blood vessels by passing a redirectable wire such as a guidewire from a relatively proximal point past the occlusion within a subintimal space formed between the intimal layer and the adventitial layer of a blood vessel wall. The wire may be advanced to a point distal to the occlusion, and thereafter deflected back into the blood vesel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. The deflecting catheter may include a flapper valve assembly or preformed actuator wire for redirecting the guidewire. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn, and the guidewire may be available for introduction of other inverventional and diagnostic catheters for performing procedures such as stenting.
摘要翻译：本发明提供了用于遍历基本上被消除的血管的方法和设备。从相对接近闭塞的点开始，重新取向的线，特别是导丝被引入由血管壁的内膜和外膜界定的内膜下空间。有可能将导线推进到远离阻塞的位置，然后将其偏转回血管内腔，通常使用推进导线的偏转导管。在其已经定位在内膜下空间之后引导。放气导管可设置有用于重新定向导丝的阀组件或预制致动器丝。在将导丝返回到血管腔后，可以移除偏转导管，这允许插入其他介入和诊断导管以进行诸如放置导管的程序。支架。

89. 发明申请

WO9956801A3 EMBOLECTOMY CATHETERS AND METHODS FOR TREATING STROKE AND OTHER SMALL VESSEL THROMBOEMBOLIC DISORDERS 审中-公开
标题翻译：用于治疗小肠和其他小血管栓塞性疾病的EMBOLECTOMY导管和方法
公开(公告)号：WO9956801A3
公开(公告)日：2000-04-06
申请号：PCT/US9909566
申请日：1999-04-30
申请人： MICROVENTION INC
发明人： ROSENBLUTH ROBERT F , COX BRIAN J , GREENE GEORGE R JR
IPC分类号： A61B17/221 , A61B17/22 , A61F2/958
CPC分类号： A61B17/22032 , A61B17/135 , A61B17/221 , A61B2017/22034 , A61B2017/22044 , A61B2017/22077 , A61B2017/22084 , A61B2017/22094 , A61B2017/2212 , A61B2017/320716 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/008 , A61F2230/0091 , A61M2025/0042 , A61M2025/0183
摘要： This invention is embolectomy catheters (11), rapid exchange micro-catheters (265), systems, and methods for removing obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, forein objects, etc.) from blood vessels. This system is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters are advanced over a guide wire (GW) which has been pre-inserted through or around the obstructive matter. These catheters include obstructive matter capturing receptacles (14) which are deployed after the catheter has been advanced at least partially through the obstructive matter. The receptacles may include at least one proximal strut (20), which is designed to be retractable through a blood clot and a distal matter-receiving portion (16) which is designed to prevent a blood clot from passing therethrough.
摘要翻译：本发明是用于从血管中去除阻塞物质（例如血栓，血栓栓塞，动脉粥样硬化斑块的栓塞片段，前列腺物体等）的移植导管（11），快速交换微导管（265），系统和方法。该系统特别可用于在脑卒中或脑缺血期期间从脑的小血管经皮去除血栓栓塞或其它阻塞物质。在一些实施例中，止血管切除导管在已经被插入穿过或围绕阻塞物质的导丝（GW）上前进。这些导管包括在导管至少部分地穿过阻塞物质前进后部署的阻塞物质捕获容器（14）。容器可以包括至少一个近端支柱（20），其被设计成可通过血块缩回并且设计成防止血块从其中通过的远端物质接受部分（16）。

90. 发明申请

WO9949793A9 CATHETERS, SYSTEMS AND METHODS FOR PERCUTANEOUS IN SITU ARTERIO-VENOUS BYPASS 审中-公开
标题翻译：导管，系统和方法在原位异常旁路旁路
公开(公告)号：WO9949793A9
公开(公告)日：2000-02-03
申请号：PCT/US9907115
申请日：1999-03-31
申请人： TRANSVASCULAR INC
发明人： FLAHERTY J CHRISTOPHER , WHITT JASON B , MACAULAY PATRICK E , THOLFSEN DAVID R , GARIBOTTO JOHN T , EVARD PHILLIP C
IPC分类号： A61B8/12 , A61B17/00 , A61B17/11 , A61B17/22 , A61B17/32 , A61B17/34 , A61B19/00 , A61M25/00 , A61M25/01
CPC分类号： A61M25/0108 , A61B17/22 , A61B17/3207 , A61B2017/00252 , A61B2017/00455 , A61B2017/22077 , A61B2090/3784 , A61B2090/3925
摘要： A system of catheter devices (10), and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel), a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.
摘要翻译：导管装置（10）的系统，以及用于在管腔解剖结构（例如血管），目标位置（例如另一血管，器官，组织块等）之间形成通道或通道的方法，用于将血流重新路由或将物质或仪器等传送到目标位置。

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