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81. 发明申请

WO2011147252A1 COMPOUND PREPARATION AND ITS USES FOR PREVENTION AND TREATMENT OF HEARING IMPAIRMENT 审中-公开
标题翻译：化合物的制备及其用于预防和治疗听觉障碍的用途
公开(公告)号：WO2011147252A1
公开(公告)日：2011-12-01
申请号：PCT/CN2011/073796
申请日：2011-05-08
申请人： THE SECOND MILITARY MEDICAL UNIVERSITY OF CHINESE PLA , GAO, Shen , GAO, Jing , ZHU, Quangang , WANG, Xiying , DING, Xueying , ZHANG, Wei , WANG, Xiaoyu , ZHANG, Min , WU, Xin , YE, Lihua
发明人： GAO, Shen , GAO, Jing , ZHU, Quangang , WANG, Xiying , DING, Xueying , ZHANG, Wei , WANG, Xiaoyu , ZHANG, Min , WU, Xin , YE, Lihua
IPC分类号： A61K31/4422 , A61K31/385 , A61P27/16
CPC分类号： A61K31/385 , A61K9/0056 , A61K9/1605 , A61K9/2004 , A61K9/4841 , A61K31/4422 , A61K2300/00
摘要： A compound preparation contains alpha-lipoic acid and nimodipine at a ratio from 5:1 to 40:1. The above-mentioned compound preparation can be used for the prevention and treatment of noise-induced hearing impairment. This compound preparation not only increases the efficacy but decreases the dosage of nimodipine, reduces the side effects and improves the patient compliance.
摘要翻译：复合制剂含有5：1至40：1的α-硫辛酸和尼莫地平。上述化合物制剂可用于预防和治疗噪声引起的听力损伤。该复方制剂不仅增加尼莫地平的疗效，而且降低剂量，降低副作用，提高患者依从性。

82. 发明申请

WO2011119565A1 IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS 审中-公开
标题翻译：用于检测神经疾病的成像剂
公开(公告)号：WO2011119565A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/029368
申请日：2011-03-22
申请人： SIEMENS MEDICAL SOLUTIONS USA, INC. , CASHION, Daniel, Kurt , CHEN, Gang , KASI, Dhanalakshmi , KOLB, Hartmuth C. , LIU, Changhui , SINHA, Anjana , SZARDENINGS, Anna, Katrin , WANG, Eric , YU, Chul , ZHANG, Wei , GANGADHARMATH, Umesh, B. , WALSH, Joseph, C.
发明人： CASHION, Daniel, Kurt , CHEN, Gang , KASI, Dhanalakshmi , KOLB, Hartmuth C. , LIU, Changhui , SINHA, Anjana , SZARDENINGS, Anna, Katrin , WANG, Eric , YU, Chul , ZHANG, Wei , GANGADHARMATH, Umesh, B. , WALSH, Joseph, C.
IPC分类号： C07D235/04 , C07D401/02 , A61K31/4184 , A61K31/4353 , A61P25/00
CPC分类号： C07D235/04 , A61K51/04 , C07B59/002 , C07D215/06 , C07D235/14 , C07D277/62 , C07D401/02 , C07D401/04 , C07D403/06 , C07D413/10 , C07D413/14 , C07D471/04 , C07D487/04
摘要： Imaging agents of formulas (I)-(V) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formulas (I)-(V) capable of binding to tau proteins and β-amyloid peptides are presented herein. The invention also relates to methods of imaging Αβ and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formulas (I)-(V) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders. Formula (V) or a pharmaceutically acceptable salt thereof, and stereoisomers thereof, wherein: X 25 -X 28 are each independently CH, CR 11 , or N; X 29 is CH, N, O or S; X 30 is CH, C, or N; X 31-34 are each independently CH, CR 12 , CR 13 or N; RII-RU are each independently H, halogen, hydroxy, nitro, cyano, ammo, alkyl, alkylaryl, alkylamino, alkylamine, arylamine, arylamino, alkoxy,— (O-CH 2 - CH 2 ) n -, alkenyL alkynyl, aryloxy, NRl0COOalkyl, NRl0 COOaryU NRW COalkyl, NR 10 CO aryl, COOalkyl, COOaryl, COalkyl, COaryl, aryl, cycloalkyl, cycloalkylamino, cycloalkylamine, bicyclic, saturated heterocycle and unsaturated heterocycle, wherein at least one carbon of R 11 -R 13 is optionally replaced with N, Q, S, triazole, or halo, and, wherein at least one hydrogen is optionally replaced with halo, amine, amino, alkoxy, nitro, alkyl, alkenyL alkynyl, aryloxy, alkylaryl, alkylamino, alkylamine, NRioCOOalkyl, NR 10 COOaryl, NR 10 COalkyl, NR,0 CO aryl, COOalkyl, COOaryl, COalkyl, COaryl, aryl, cycloalkyl, cycloalkylamino, cycloalkylamine, bicyclic saturated heterocycle and unsaturated heterocycle, a leaving group, CN, OH or a radioactive isotope.
摘要翻译：式（I） - （V）的成像剂和用于检测神经障碍的方法包括向需要的患者施用能够结合tau蛋白和β-淀粉样肽的式（I） - （V）化合物。本发明还涉及成像β和tau聚集体的方法，包括引入可检测量的包含放射性标记的式（I） - （V）化合物的药物制剂，并检测与淀粉样蛋白沉积物和/或tau蛋白相关的标记化合物患者。这些方法和组合使得临床前诊断和监测AD和其他神经障碍的进展。式（V）或其药学上可接受的盐及其立体异构体，其中：X25-X28各自独立地为CH，CR11或N; X29是CH，N，O或S; X30是CH，C或N; X31-34各自独立地为CH，CR12，CR13或N; RII-RU各自独立地为H，卤素，羟基，硝基，氰基，氨基，烷基，烷基芳基，烷基氨基，烷基胺，芳基胺，芳基氨基，烷氧基， - （O-CH 2 -CH 2）n - 烯基炔基，芳氧基，NR 10 COO烷基， NR10 COOaryU NRW CO烷基，NR10CO芳基，COO烷基，COO芳基，CO烷基，芳基，芳基，环烷基，环烷基氨基，环烷基胺，双环，饱和杂环和不饱和杂环，其中R11-R13的至少一个碳任选被N，Q，烷基，烯基炔基，芳氧基，烷基芳基，烷基氨基，烷基胺，NROCOO烷基，NR10 COO芳基，NR10CO烷基，NR 芳基，环烷基，环烷基氨基，环烷基胺，双环饱和杂环和不饱和杂环，离去基团，CN，OH或放射性同位素。

83. 发明申请

WO2011116359A2 ORGANIC POROUS MATERIALS COMPRISING SHAPE-PERSISTENT THREE-DIMENSIONAL MOLECULAR CAGE BUILDING BLOCKS 审中-公开
标题翻译：包含形状三维分子笼建筑块的有机多孔材料
公开(公告)号：WO2011116359A2
公开(公告)日：2011-09-22
申请号：PCT/US2011/029103
申请日：2011-03-18
申请人： THE REGENTS OF THE UNIVERSITY OF COLORADO , ZHANG, Wei , NOBLE, Richard, D. , JIN, Yinghua , VOSS, Bret, A.
发明人： ZHANG, Wei , NOBLE, Richard, D. , JIN, Yinghua , VOSS, Bret, A.
IPC分类号： B01D53/02
CPC分类号： B01D53/02 , B01D2253/20 , B01D2253/202 , B01D2257/504 , B01J20/267 , B01J20/28007 , B01J20/28045 , B01J20/3212 , B01J20/3236 , B82Y30/00 , Y02C10/08

84. 发明申请

WO2011113803A1 LAUNDRY PROCESSING APPARATUS WITH DRYING PROCEDURE 审中-公开
标题翻译：具有干燥程序的洗衣加工设备
公开(公告)号：WO2011113803A1
公开(公告)日：2011-09-22
申请号：PCT/EP2011/053827
申请日：2011-03-15
申请人： BSH BOSCH UND SIEMENS HAUSGERÄTE GMBH , ZHANG, Wei , LI, Weichen , LIU, Yongqing , YANG, Huijia
发明人： ZHANG, Wei , LI, Weichen , LIU, Yongqing , YANG, Huijia
IPC分类号： D06F58/22 , D06F58/24
CPC分类号： D06F58/22 , D06F58/24
摘要： A laundry processing apparatus 1 with a drying procedure is provided, for drying laundry through continuous air cycles when the drying procedure is performed, which includes a condensing unit 5 for condensing the cycled air; and a spraying device 7 with a telescopic spray head structure 9, for spraying water onto the condensing unit 5 via the spray head structure 9 to rinse every corner of the condensing unit 5, which greatly increases the spraying area, thereby covering the whole condensing unit 5 as far as possible, and effectively ensuring the rinsing effect.
摘要翻译：提供一种具有干燥程序的洗衣处理装置1，用于当执行干燥过程时通过连续空气循环来干燥衣物，其包括用于冷凝循环空气的冷凝单元5; 以及具有伸缩喷头结构9的喷涂装置7，用于经由喷头结构9将水喷射到冷凝单元5上，以冲洗冷凝单元5的每个角落，这大大增加了喷射面积，从而覆盖整个冷凝单元 5尽可能地，有效保证冲洗效果。

85. 发明申请

WO2011059821A2 CYCLOHEXANE-1,3-DIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS 审中-公开
标题翻译： CYCLOHEXANE-1,3-DIONES用于治疗左心室狭窄症
公开(公告)号：WO2011059821A2
公开(公告)日：2011-05-19
申请号：PCT/US2010/054747
申请日：2010-10-29
申请人： CAMBRIA PHARMACEUTICALS, INC. , NORTHWESTERN UNIVERSITY , KIRSCH, Donald, R. , BENMOHAMED, Radhia , ARVANITES, Anthony, C. , MORIMOTO, Richard, I. , ZHANG, Wei , SILVERMAN, Richard, B.
发明人： KIRSCH, Donald, R. , BENMOHAMED, Radhia , ARVANITES, Anthony, C. , MORIMOTO, Richard, I. , ZHANG, Wei , SILVERMAN, Richard, B.
CPC分类号： C07C69/75 , A61K31/136 , C07C49/563 , C07C49/567 , C07C49/577
摘要： The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds.
摘要翻译：本发明涉及提供的环己烷-1,3-二酮（CHD化合物）及其药物组合物的鉴定，用于治疗肌萎缩性侧索硬化（ALS）和其它神经变性疾病的受试者。本发明还提供了制备所提供的CHD化合物的方法。

86. 发明申请

WO2010114746A1 POLYOLS MADE FROM PARTIALLY-EPOXIDIZED, FULLY-HYDROGENATED FATTY ACID ALKYL ESTERS 审中-公开
标题翻译：从部分环氧化，全氢化脂肪酸的酸碱产生的多酚
公开(公告)号：WO2010114746A1
公开(公告)日：2010-10-07
申请号：PCT/US2010/028329
申请日：2010-03-23
申请人： CARGILL, INCORPORATED , ABRAHAM, Timothy Walter , ZHANG, Wei
发明人： ABRAHAM, Timothy Walter , ZHANG, Wei
IPC分类号： C08J11/04
CPC分类号： C08G18/36 , C08G2101/00
摘要： A method is described for producing polyester polyols by partially-epoxidizing fatty acid alkyl esters having an iodine value from 90 to 190g I2/100 grams, fully-hydrogenating the partially-epoxidized esters to form hydroxylated fatty acid alkyl esters, and then reacting the hydroxylated fatty acid alkyl esters with a multifunctional ester-reactive initiator compound to form the polyester polyol.
摘要翻译：描述了通过部分环氧化碘值为90至190g I2 / 100克的脂肪酸烷基酯制备聚酯多元醇的方法，将部分环氧化的酯完全氢化以形成羟基化脂肪酸烷基酯，然后使羟基化脂肪酸烷基酯与多官能酯反应引发剂化合物形成聚酯多元醇。

87. 发明申请

WO2009101537A2 ROBUST COOPERATIVE SPECTRUM SENSING FOR COGNITIVE RADIOS 审中-公开
标题翻译：认知无线电的鲁棒协作频谱感知
公开(公告)号：WO2009101537A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/005358
申请日：2009-02-12
申请人： THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY , BEN LETAIEF, Khaled , ZHANG, Wei
发明人： BEN LETAIEF, Khaled , ZHANG, Wei
CPC分类号： H04L5/0032 , H04B7/026 , H04B7/15592 , H04L1/0077 , H04L1/0606 , H04L1/0618 , H04L5/0062 , H04L5/0091 , H04L27/0006 , H04W16/14
摘要： The disclosed subject matter relates to communicatively coupled cognitive radio systems, devices, and methodologies facilitating utilization by secondary users of portions of spectral bands unused by primarily users. This utilization can be achieved by cooperative spectrum sensing employing ST coding and/or SF coding for transmit diversity. Further, cooperative spectrum sensing can be improved by employing relay diversity with or without algebraic coding. A threshold probability of false alarm can be reduced by applying transmit diversity with space time coding and/or space frequency coding. Further, relay diversity can be employed to compensate for reduced sensing diversity order were some nodes in a cooperative spectrum sensing system cannot report directly. Algebraic coding can be combined with relay diversity to decrease the threshold probability of false alarm in relay diversity systems while maintaining high levels of sensing diversity order.
摘要翻译：所公开的主题涉及通信地耦合的认知无线电系统，设备和方法，其帮助次要用户利用主要用户未使用的频谱带的部分。这种利用可以通过使用ST编码和/或用于发射分集的SF编码的协作频谱感测来实现。此外，通过采用或不采用代数编码的中继分集，可以改善协作频谱感测。通过应用具有空时编码和/或空间频率编码的发射分集，可以减少虚警的阈值概率。此外，可以采用中继分集来补偿协作频谱感测系统中的一些节点不能直接报告的降低的感测分集顺序。代数编码可以与中继分集相结合，以降低中继分集系统中虚警的阈值概率，同时保持高水平的传感分集顺序。

88. 发明申请

WO2009074282A1 BRENNSTOFFZELLE, PROTONEN LEITENDE MEMBRAN, MEMBRAN-ELEKTRODEN- EINHEIT, VERWENDUNGEN VON LONOMEREN UND KIT 审中-公开
标题翻译：燃料电池中，质子传导膜，膜电极组件，离聚物和试剂盒的用途
公开(公告)号：WO2009074282A1
公开(公告)日：2009-06-18
申请号：PCT/EP2008/010425
申请日：2008-12-09
申请人： FUMA-TECH GESELLSCHAFT FÜR FUNKTIONELLE MEMBRANEN UND ANLAGENTECHNOLOGIE MBH , BAUER, Bernd , JESKE, Michael , RISCHER, Norbert , SCHUSTER, Michael , ZHANG, Wei
发明人： BAUER, Bernd , JESKE, Michael , RISCHER, Norbert , SCHUSTER, Michael , ZHANG, Wei
IPC分类号： H01M8/10
CPC分类号： H01M8/1032 , H01M8/1067 , H01M2300/0082 , H01M2300/0094
摘要： Die vorliegende Erfindung betrifft eine Brennstoffzelle mit Elektroden in Form einer Anode und einer Kathode, zwischen denen eine Protonen leitende Membran aus einem acide Gruppe aufweisenden lonomer angeordnet ist, die Wasser anzuziehen vermag, das an die aciden Gruppen bindet, wobei zwischen dem Bereich der Anode und dem Bereich der Kathode ein Gradientenprofil in Bezug auf das Wasseranziehungsvermögen des lonomers ausgebildet ist, derart, dass das Wasseranziehungsvermögen im Anodenbereich größer ist als im Kathodenbereich.
摘要翻译：本发明涉及一种具有在阳极和阴极，在其之间具有一个酸性基团的导电膜中的质子被布置离聚物是能够吸引水，其结合酸性基团，其中所述阳极的面积之间的形式，和电极的燃料电池阴极的区域中，形成相对于离子交联聚合物，使得阳极区域的水接受能力比在阴极区域大的水接受性的梯度。

89. 发明申请

WO2009040678A4 MULTIUSER SCHEDULING FOR MIMO BROADCAST CHANNELS WITH FINITE RATE FEEDBACK 审中-公开
公开(公告)号：WO2009040678A4
公开(公告)日：2009-04-02
申请号：PCT/IB2008/003485
申请日：2008-04-29
申请人： THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY , ZHANG, Wei , BEN LETAIEF, Khaled
发明人： ZHANG, Wei , BEN LETAIEF, Khaled
IPC分类号： H04W24/10 , H04B7/02 , H04L1/04 , H04L1/06
摘要： System and methodologies are provided herein for multiuser scheduling in a multiple-input multiple-output (MIMO) communication system. Various aspects described herein facilitate full feedback scheduling, wherein multiuser scheduling is performed based on an antenna selection and signal quality feedback, such as signal-to-interference-plus-noise ratio (SINR) feedback, from respective users. Based on information received from respective users, independent information streams can be transmitted from respective transmit antennas to respective users with the highest signal quality. Receive antenna selection can also be employed to allow respective users to select a single receive antenna on which information is to be received. Additional aspects described herein facilitate quantized feedback scheduling, wherein scheduling is performed based on signal quality feedback that is quantized into a finite number of bits by respective users.

90. 发明申请

WO2009039666A1 FLEXIBLE SOLAR MODULE AND METHOD OF MAKING SAME 审中-公开
标题翻译：柔性太阳能模块及其制造方法
公开(公告)号：WO2009039666A1
公开(公告)日：2009-04-02
申请号：PCT/CA2008/001729
申请日：2008-09-29
申请人： MCMASTER UNIVERSITY , KITAI, Adrian Howard , ZHANG, Wei , ZHU, Yanxia
发明人： KITAI, Adrian Howard , ZHANG, Wei , ZHU, Yanxia
IPC分类号： H01L31/0232 , H01L27/142 , H01L31/045 , H01L31/052 , H01L31/18
CPC分类号： H01L31/046 , H01L31/05 , H01L31/0547 , H02S30/20 , Y02E10/52
摘要： A flexible solar module is disclosed comprising a plurality of electrically interconnected solar cell chips arranged in an array and a plurality of optical elements adhered directly to each of the plurality of solar cell chips which direct light to the plurality of solar cell chips. The optical elements are adhered to the solar cell chips such that there are no air gaps between the plurality of solar cell chips and the plurality of optical elements. The area of the light collecting area of each of the plurality of optical elements may be equal to or greater than the area of the top each of the solar cell chips.
摘要翻译：公开了一种柔性太阳能模块，其包括排列成阵列的多个电互连的太阳能电池芯片，并且多个光学元件直接粘附到将多个太阳能电池芯片引导到多个太阳能电池芯片的每一个上。光学元件粘附到太阳能电池芯片，使得在多个太阳能电池芯片和多个光学元件之间不存在气隙。多个光学元件中的每一个的聚光区域的面积可以等于或大于太阳能电池芯片顶部的面积。

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