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81. 发明申请

WO2007015790A3 RESONATOR FOR MEDICAL DEVICE 审中-公开
标题翻译：医疗器械共振器
公开(公告)号：WO2007015790A3
公开(公告)日：2007-05-10
申请号：PCT/US2006027598
申请日：2006-07-14
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN
发明人： WEBER JAN
IPC分类号： A61B5/055 , A61F2/86 , G01R33/28
CPC分类号： A61F2/86 , A61B5/055 , A61F2230/0091 , A61F2250/0001 , A61F2250/0045 , G01R33/286
摘要： A resonator device (100) including an induction coil, a conductive member (104) positioned adjacent the induction coil (102) , and a dielectric layer between at least a portion of the induction coil and the conductive member to form a capacitor structure. In one embodiment, the conductive member can be a stent (106) . In an alterative embodiment, the conductive member can be a conductive film. In an additional embodiment, the dielectric layer can have a dielectric constant that changes in a predetermined fashion between at least a portion of the induction coil and the conductive member to allow for a uniform current distribution in the resonator device. The dielectric layer can also include a flexible elongate body.
摘要翻译：包括感应线圈，位于感应线圈（102）附近的导电部件（104）的谐振器装置（100）以及感应线圈的至少一部分与导电部件之间形成电容器结构的电介质层。在一个实施例中，导电构件可以是支架（106）。在替代实施例中，导电构件可以是导电膜。在另外的实施例中，电介质层可以具有在感应线圈的至少一部分和导电构件之间以预定方式改变的介电常数，以允许谐振器装置中的均匀电流分布。电介质层还可以包括柔性细长体。

82. 发明申请

WO2006081419A8 MEDICAL DEVICES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：医疗器械及其制造方法
公开(公告)号：WO2006081419A8
公开(公告)日：2007-01-18
申请号：PCT/US2006002924
申请日：2006-01-25
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , SPENCER STEVEN M
发明人： WEBER JAN , SPENCER STEVEN M
CPC分类号： A61M25/1029 , A61L27/50 , A61L29/14 , A61M25/0009 , A61M2025/1031
摘要： Medical devices and methods of making the devices are described. In some embodiments, a method of making a medical device includes addressing a member including a polymer with energy above an ablation threshold of the polymer, and using the member to make the medical device.
摘要翻译：描述了制造装置的医疗装置和方法。在一些实施方案中，制造医疗装置的方法包括使包含聚合物的物质寻址，所述聚合物具有高于聚合物的消融阈值的能量，并且使用该构件制造医疗装置。

83. 发明申请

WO2006015386A3 A METHOD OF MAKING A COATED MEDICAL DEVICE 审中-公开
标题翻译：制造涂层医疗装置的方法
公开(公告)号：WO2006015386A3
公开(公告)日：2006-11-09
申请号：PCT/US2005027890
申请日：2005-08-04
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , KOCUR GORDON J , HELMUS MICHAEL , PALASIS MARIA
发明人： WEBER JAN , KOCUR GORDON J , HELMUS MICHAEL , PALASIS MARIA
IPC分类号： A61L33/00 , A61F2/06 , B05D1/36
CPC分类号： A61L31/16 , A61F2250/0068 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/606
摘要： Medical devices, such as stents, having a surface, a coating layer comprising a polymer disposed on at least a portion of the surface, and a composition comprising a biologically active material injected into or under the coating layer at one or more locations in the coating layer to form at least one pocket containing a biologically active material are disclosed. The composition may be injected using a nanometer- or micrometer-sized needle. Methods for making such medical devices are also disclosed. Using this method, a precise amount of the biologically active material may be disposed accurately and efficiently on the medical device at predefined locations.
摘要翻译：医疗装置，例如具有表面的支架，包括设置在表面的至少一部分上的聚合物的涂层，以及包含在涂层中的一个或多个位置处注入到涂层内或之下的生物活性物质的组合物层以形成至少一个包含生物活性材料的口袋。可以使用纳米或微米尺寸的针注射组合物。还公开了制造这种医疗装置的方法。使用该方法，精确量的生物活性材料可以在预定义的位置处精确而有效地设置在医疗装置上。

84. 发明申请

WO2006081419A2 MEDICAL DEVICES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：医疗器械及其制造方法
公开(公告)号：WO2006081419A2
公开(公告)日：2006-08-03
申请号：PCT/US2006002924
申请日：2006-01-25
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , SPENCER STEVEN M
发明人： WEBER JAN , SPENCER STEVEN M
CPC分类号： A61M25/1029 , A61L27/50 , A61L29/14 , A61M25/0009 , A61M2025/1031
摘要： Medical devices and methods of making the devices are described. In some embodiments, a method of making a medical device includes addressing a member including a polymer with energy above an ablation threshold of the polymer, and using the member to make the medical device.
摘要翻译：描述了制造装置的医疗装置和方法。在一些实施方案中，制造医疗装置的方法包括使包含聚合物的物质寻址，所述聚合物具有高于聚合物的消融阈值的能量，并且使用该构件制造医疗装置。

85. 发明申请

WO2006026187A3 STENTS WITH DRUG DELIVERY COATINGS 审中-公开
标题翻译：与药物输送涂料相提并论
公开(公告)号：WO2006026187A3
公开(公告)日：2006-05-26
申请号：PCT/US2005029529
申请日：2005-08-18
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN
发明人： WEBER JAN
IPC分类号： A61L31/02 , A61L31/10 , A61L31/16
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/624
摘要： The present invention relates generally to medical devices, preferably a stent, having a drug eluting surface coated or covered with a coating of particles comprising at least an outer layer, an inner layer, and a core comprising a therapeutic agent. Specifically, the invention relates to medical devices having a hydrophilic coating comprising particles with a hydrophilic outer layer, a hydrophobic inner layer, and a core comprising a hydrophobic therapeutic agent, as well as medical devices having a hydrophobic coating comprising particles with a hydrophobic outer layer, a hydrophilic inner layer, and a core comprising a hydrophilic therapeutic agent. The coating, outer layer, and inner layer are preferably biodegradable and capable of providing sustained release of the therapeutic agent over a time period. The invention also relates to methods of making and methods of using the coated or covered medical device.
摘要翻译：本发明一般涉及医疗装置，优选支架，其具有用包含至少外层，内层和包含治疗剂的芯的颗粒涂层涂覆或覆盖的药物洗脱表面。具体地，本发明涉及具有亲水性涂层的医疗装置，其包括具有亲水外层的颗粒，疏水性内层和包含疏水性治疗剂的芯，以及具有疏水性涂层的医疗装置，所述疏水涂层包含具有疏水性外层的颗粒，亲水性内层和包含亲水性治疗剂的核心。涂层，外层和内层优选是可生物降解的并且能够在一段时间内提供治疗剂的持续释放。本发明还涉及制造方法和使用涂覆或覆盖的医疗装置的方法。

86. 发明申请

WO2009033082A3 MEDICAL DEVICES CONTAINING SILICATE AND CARBON PARTICLES 审中-公开
标题翻译：含有硅酸盐和碳颗粒的医疗器械
公开(公告)号：WO2009033082A3
公开(公告)日：2010-01-28
申请号：PCT/US2008075475
申请日：2008-09-05
申请人： BOSTON SCIENT LTD , CHEN JOHN JIANHUA , HORN DANIEL J , ATANASOSKA LILIANA , WEBER JAN
发明人： CHEN JOHN JIANHUA , HORN DANIEL J , ATANASOSKA LILIANA , WEBER JAN
IPC分类号： A61L29/12 , A61L29/02 , A61L29/16 , A61L31/02 , A61L31/12 , A61L31/16
CPC分类号： A61L31/026 , A61L29/02 , A61L29/103 , A61L29/126 , A61L29/16 , A61L31/02 , A61L31/024 , A61L31/084 , A61L31/126 , A61L31/16 , A61L2300/416
摘要： According to one aspect of the present invention, implantable and insertable medical devices are provided which contain one or more particle-containing regions that comprise silicate particles and carbon particles.
摘要翻译：根据本发明的一个方面，提供了可植入和可插入的医疗装置，其包含一个或多个包含硅酸盐颗粒和碳颗粒的含颗粒的区域。

87. 发明申请

WO2007098353A3 BIOERODIBLE ENDOPROSTHESES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：可生物降解的内生物及其制备方法
公开(公告)号：WO2007098353A3
公开(公告)日：2009-05-07
申请号：PCT/US2007062178
申请日：2007-02-15
申请人： BOSTON SCIENT LTD , WEBER JAN , ATANASOSKA LILIANA , KONDYURIN ALEXEY
发明人： WEBER JAN , ATANASOSKA LILIANA , KONDYURIN ALEXEY
IPC分类号： A61F2/82 , A61L31/00
CPC分类号： A61L31/148 , A61L31/084 , A61L2400/18
摘要： Endoprostheses include a wall having a base, e.g., a bioerodible base, and a polymer that may include a region of carbonized polymer formed by implantation.
摘要翻译：内用假体包括具有基底例如生物可侵蚀基底的壁和可以包括通过植入形成的碳化聚合物区域的聚合物。

88. 发明申请

WO2008034048A3 BIOERODIBLE ENDOPROSTHESIS WITH BIOSTABLE INORGANIC LAYERS 审中-公开
标题翻译：生物可溶性无机物的生物化学性质
公开(公告)号：WO2008034048A3
公开(公告)日：2009-03-19
申请号：PCT/US2007078476
申请日：2007-09-14
申请人： BOSTON SCIENT LTD , WEBER JAN , ATANASOSKA LILIANA , SCHEWE SCOTT R
发明人： WEBER JAN , ATANASOSKA LILIANA , SCHEWE SCOTT R
IPC分类号： A61L31/08
CPC分类号： A61L31/16 , A61L31/022 , A61L31/082 , A61L2300/416
摘要： Medical devices such as endoprostheses (e.g., stents) containing one or more biostable layers (e.g., biostable inorganic layers) and a biodegradable underlying structure are disclosed.
摘要翻译：公开了包含一个或多个生物稳定层（例如生物稳定无机层）和可生物降解的底层结构的内用假体（例如，支架）的医疗装置。

89. 发明申请

WO2007103356A3 MEDICAL DEVICES HAVING ELECTRICALLY ALIGNED ELONGATED PARTICLES 审中-公开
标题翻译：具有电气对准的长条形颗粒的医疗装置
公开(公告)号：WO2007103356A3
公开(公告)日：2008-11-20
申请号：PCT/US2007005658
申请日：2007-03-05
申请人： BOSTON SCIENT LTD , WEBER JAN , ATANASOSKA LILIANA
发明人： WEBER JAN , ATANASOSKA LILIANA
IPC分类号： A61L27/44 , A61L27/42 , A61L27/48 , A61L29/12 , A61L31/12
CPC分类号： B82Y30/00 , A61K47/6957 , A61L27/28 , A61L27/40 , A61L29/08 , A61L29/12 , A61L31/08 , A61L31/121 , A61L31/125 , B82Y5/00
摘要： Medical devices configured for implantation or insertion into a subject, which contain one or more particle-containing region that comprises electrically aligned, elongated particles within a matrix. Also described are methods for forming the same.
摘要翻译：构造成用于植入或插入受试者的医疗装置，其包含一个或多个在基质内包含电配对的细长颗粒的含颗粒区域。还描述了其形成方法。

90. 发明申请

WO2008083069A3 BIOERODIBLE NANO-FIBROUS AND NANO-POROUS CONDUCTIVE COMPOSITES 审中-公开
标题翻译：可生物降解的纳米纤维和纳米多孔导电复合材料
公开(公告)号：WO2008083069A3
公开(公告)日：2009-07-16
申请号：PCT/US2007088533
申请日：2007-12-21
申请人： BOSTON SCIENT LTD , ATANASOSKA LILIANA , FENG JAMES Q , WEBER JAN , SHIPPY III JAMES LEE
发明人： ATANASOSKA LILIANA , FENG JAMES Q , WEBER JAN , SHIPPY III JAMES LEE
IPC分类号： A61L27/14 , A61L31/10
CPC分类号： A61L27/40 , A61L27/14 , A61L27/50 , A61L27/58 , A61L2400/12
摘要： A bioerodible conductive tissue scaffold that can provide, e.g., improved tissue growth.
摘要翻译：可以提供例如改善的组织生长的生物蚀蚀性导电组织支架。

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