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61. 发明申请

WO1993009840A1 BIPOLAR TEMPORARY PACING LEAD AND CONNECTOR AND PERMANENT BIPOLAR NERVE WIRE 审中-公开
标题翻译：双极板太阳能电线和连接器和永久双极线
公开(公告)号：WO1993009840A1
公开(公告)日：1993-05-27
申请号：PCT/US1992009997
申请日：1992-11-17
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , CAMPS, Antoine, Nicolaas, Jean-Marie , GRANDJEAN, Pierre, Andre , JOHNSON, Gary, M. , LEE, Philip, H., J. , LOKHOFF, Nicolaas, Matheus, Henricus , VAN DRIEL, Willem, Johan
IPC分类号： A61N01/05
CPC分类号： A61N1/0551 , A61N1/0558 , A61N1/0595
摘要： One aspect of this invention relates to a temporary heart wire, and external connector therefore, and the combination of the two, wherein the distal end of the heart wire includes a temporary affixation coil (8) and distal pacing (2) and sensing (1) electrodes connected by means of a coaxial helicoidally wound cable (3) to a proximal electrode (7) and a breakaway needle (6) which also serves as a proximal electrode. The lead is adapted to be inserted into a disposable connector having a snap aperture element (19) for receiving the breakaway needle, and about which the needle is broken, as well as electrical contacts (17, 18) for contacting the proximal electrodes and adapted to be connected to a temporary external pacemaker. According to another aspect of this invention, there is provided a permanent bipolar nerve electrode which includes two electrodes (52, 54) adapted to be positioned along the nerve trunk (58). The bipolar nerve electrode further includes an affixation coil (56) and a thin insulation layer or flap (57), this latter being adapted to be sutured to the surface of the patient's muscle to thereby preclude or limit stimulating electrical energy to be transmitted to adjacent muscles, this allowing for a more focused concentration of electrical energy to the nerve trunk (58) to be stimulated.

62. 发明申请

WO1993008871A1 IMPLANTABLE LEAD SYSTEM 审中-公开
标题翻译：可塑性铅系统
公开(公告)号：WO1993008871A1
公开(公告)日：1993-05-13
申请号：PCT/US1992005096
申请日：1992-06-17
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , UPTON, James, E. , WILLIAMS, Terrell, M. , JULA, James , RYDEN, Johan, S. , BLANKENAU, Paul, D.
IPC分类号： A61N01/05
CPC分类号： A61N1/3752 , A61N1/05 , A61N1/056 , A61N1/0573 , A61N2001/0578
摘要： An implantable active fixation lead system which connects a source of electrical energy, such as a pacemaker, to the cardiac tissue. The lead system includes a lead, an introducer and a guide catheter. The lead has a small diameter lead body, and an active fixation device for engaging the cardiac tissue. The lead body has an overall straight, uncoiled configuration, and an outer diameter of about 13 mils. The lead body includes a plurality of infinitesimal, bio-compatible, bio-stable electrically conductive strands which are tightly bundled together in a cable-like fashion to form a single conductor. A dielectric bio-compatible insulation coating surrounds the conductor to provide an insulation layer between the conductor and the body environment. The fixation device includes a crank portion which engages the introducer. The introducer is assembled to the lead and includes a coupler which engages the crank portion of the lead fixation device. The coupler includes a closely wound coil, and an elongated generally cylindrical tip engaging member having an aperture which acts as an entranceway for the lead fixation device. The coupler retains and firmly engages the lead crank portion, and controls its engagement to, and disengagement from the cardiac tissue. Furthermore, the coupler prevents the lead active fixation device for overperforating the cardiac tissue. A catheter is assembled to the lead and the introducer, for imparting stiffness and improved steerability to the lead.

63. 发明申请

WO1992015363A1 STEROID ELUTING INTRAMUSCULAR LEAD 审中-公开
公开(公告)号：WO1992015363A1
公开(公告)日：1992-09-17
申请号：PCT/US1991009546
申请日：1991-12-23
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , GRANDJEAN, Pierre, A. , LEE, Philip , BOURGEOIS, Ivan
IPC分类号： A61N01/05
CPC分类号： A61B17/06166 , A61M1/1003 , A61M1/1037 , A61M1/1068 , A61M1/107 , A61M1/12 , A61M1/122 , A61M1/127 , A61N1/05 , A61N1/0587 , A61N1/36042
摘要： An intramuscular lead for electrically stimulating muscle tissue particularly configured for a cardiac assist system powered by surgically modified skeletal muscle tissue. Electrical stimulation is supplied via the intramuscular lead to cause contraction of the skeletal muscle in synchrony with the natural or artificially paced heart rate and timed to obtain the desired hemodynamic effect. The improved lead has an electrode which is embedded in the skeletal muscle. The stimulation threshold of the skeletal muscle is held relatively low by the action of a glucocorticosteroid imbedded within the strand of suture material. A spacer coil of biocompatible material is coiled around the strand of suture material, such that the turns of both coils are substantially interleaved. The spacer coil is saturated with a specific agent such as steroid or antibiotic. The compression movement of the muscle tissue and the electrode coil against the spacer coil will cause the drug to be dispensed therefrom.
摘要翻译：用于电刺激肌肉组织的肌内引线，特别配置用于通过手术改良的骨骼肌组织供电的心脏辅助系统。电刺激通过肌肉内引起，以与天然或人为节奏的心率同步地引起骨骼肌的收缩并定时获得所需的血液动力学效应。改进的铅具有嵌入在骨骼肌中的电极。骨骼肌的刺激阈值通过嵌入在缝线材料股线内的糖皮质激素的作用而保持相对较低。生物相容性材料的间隔线圈卷绕在缝合线材料的股线上，使得两个线圈的匝基本交错。间隔线圈用特定药剂如类固醇或抗生素饱和。肌肉组织和电极线圈相对于间隔线圈的压缩运动将导致药物被分配。

64. 发明申请

WO1992014510A1 VAGINAL PROBE 审中-公开
公开(公告)号：WO1992014510A1
公开(公告)日：1992-09-03
申请号：PCT/FR1992000160
申请日：1992-02-20
申请人： PEZ, René
IPC分类号： A61N01/05
CPC分类号： A61N1/0524 , A61B10/0012 , A61B2010/0016
摘要： A vaginal probe comprises a cylindrical body (1) with at least two electrodes on its outer surface isolated from each other, each electrode being connected to one of the terminals (5, 5') of a low frequency current supply. Said probe is characterized in that each electrode is composed of a conductive strip (4, 4') spirally wound on the surface of the probe body (1).

65. 发明申请

WO1992007616A1 IMPLANTABLE DEFIBRILLATION ELECTRODE AND METHOD OF MANUFACTURE 审中-公开
标题翻译：可植入的定位电极及其制造方法
公开(公告)号：WO1992007616A1
公开(公告)日：1992-05-14
申请号：PCT/US1991006388
申请日：1991-09-06
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , SMITS, Karel F., A., A. , CAMPS, Antoine
IPC分类号： A61N01/05
CPC分类号： A61N1/0587
摘要： A defibrillation electrode fabricated by molding an elongated electrode core taking the form of two parallel segments each defining several sigmoidal curves (12, 14), sliding a conductor coil (20) over and along the electrode core, coupling the electrode coil (20) to an elongated conductor (24), molding bridging members (18) to connect the two segments of the core at spaced locations along the segments and molding a transition member (22) to the electrode assembly (10) at the junction of the electrode coil (20) and the elongated conductor (24). The resulting electrode is particularly adapted for use as an epicardial defibrillation electrode, and displays flexibility within the plane defined by the electrode body as well as for twisting and other deformation to follow the changing surface of the heart during contractions.

66. 发明申请

WO1991017791A1 ANNULAR NEURAL ELECTRODE 审中-公开
标题翻译：环形神经电极
公开(公告)号：WO1991017791A1
公开(公告)日：1991-11-28
申请号：PCT/FR1991000404
申请日：1991-05-21
申请人： SOURIAU & CIE , DE MENDEZ, Michel , CHINCHOLLE-GAMBOA, Sylvie , CONTARDO, Laurent
发明人： SOURIAU & CIE
IPC分类号： A61N01/05
CPC分类号： A61B5/04001 , A61F2210/0019 , A61N1/0551 , A61N1/0556
摘要： Annular neural electrode for producing, in a given working temperature range, an electricl contact on the periphery of a nerve (10) such as to induce electrical excitation. In accordance with the invention, said electrode is made from a shape memory material capable of showing, in said working temperature range, a super elastic effect in conjunction with its transformation under stress from the austenitic phase to the martensitic phase. Application in electrical muscle stimulation.

67. 发明申请

WO1991012850A1 STEROID ELUTING CUFF ELECTRODE FOR PERIPHERAL NERVE STIMULATION 审中-公开
标题翻译：用于外周神经刺激的STEROID ELUTING CUFF电极
公开(公告)号：WO1991012850A1
公开(公告)日：1991-09-05
申请号：PCT/US1991000810
申请日：1991-02-06
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , LEE, Philip , GATES, James , STOKES, Kenneth, B. , JOHNSON, Gary
IPC分类号： A61N01/05
CPC分类号： A61N1/0556
摘要： An electrode for establishing electrical contact with a nerve of a patient has an outer cuff (15) of an insulating material which is sutured around the nerve to be contacted. A drug impregnated layer (16) of material is positioned inside of the outer cuff. This material is a polymeric matrix which permits the drug to leach out at a predetermined rate. The drug is a steroid such as dexamethasone sodium phosphate. The actual electrical contact is produced by metallic foil (12, 13) which is positioned on the surface of the drug impregnated layer of material which is located inside of the cuff. An insulated lead (9) electrically couples the metallic foil to an electronic circuit located remote from the nerve. The leaching out of the drug serves to control irritation, swelling and impedance of the nerve/electrode interface.
摘要翻译：用于与患者的神经建立电接触的电极具有绝缘材料的外部袖带（15），所述绝缘材料缝合在被接触的神经周围。药物浸渍层（16）的材料位于外套筒的内部。该材料是允许药物以预定速率浸出的聚合物基质。该药物是类固醇，如地塞米松磷酸钠。实际的电接触由金属箔（12,13）制成，金属箔位于位于袖带内部的药物浸渍材料层的表面上。绝缘引线（9）将金属箔电耦合到远离神经的电子电路。药物的浸出用于控制神经/电极界面的刺激，肿胀和阻抗。

68. 发明申请

WO1989006148A1 AN INTRAVASCULAR ELECTRODE LEAD USABLE FOR CARDIAC DEFIBRILLATION 审中-公开
标题翻译：可用于心脏缺血的静脉电极引线
公开(公告)号：WO1989006148A1
公开(公告)日：1989-07-13
申请号：PCT/SE1989000002
申请日：1989-01-09
申请人： EDHAG, Knut, Olof
IPC分类号： A61N01/05
CPC分类号： A61N1/3956 , A61N1/0563
摘要： An intravascular electrode lead usable for cardiac defibrillation comprises a lead body (11) and an electrode arrangement (12) carried by said lead body and insertable into an atrial or ventricular room, said electrode arrangement comprising a number of elongate flexible electrodes (13). The electrodes (13) are anchored to the lead body (11) adjacent to each other at their one ends. For the rest, they are resiliently movable in relation to the lead body (11) from laterally retracted positions, in which they are located adjacent to each other, to laterally expanded positions, in which they may bear resiliently against the surrounding wall (22) of said room.
摘要翻译：可用于心脏除颤的血管内电极引线包括引线体（11）和由所述引线体承载并可插入心房或室室的电极装置（12），所述电极装置包括多个细长的柔性电极（13）。电极（13）在它们的一端相互邻近地锚定到引线本体（11）。对于其余部分，它们相对于引线本体（11）能够相对于彼此相邻定位的横向缩回位置弹性移动到横向扩展位置，在该位置上它们可弹性地抵靠在周围壁（22）上，的房间。

69. 发明申请

WO1998030277A1 APPARATUS FOR STIMULATING LIVING TISSUE 审中-公开
标题翻译：刺激生活组织的装置
公开(公告)号：WO1998030277A1
公开(公告)日：1998-07-16
申请号：PCT/US1997019046
申请日：1997-10-20
申请人： BOUTOS, David
IPC分类号： A61N01/05
CPC分类号： A61N1/0456 , A61N1/0408 , A61N1/0452 , A61N1/0472 , A61N1/0512 , A61N1/0524 , A61N1/36007
摘要： Electrodes (700, 750, 780) for stimulating living tissue such as penile, scrotal, anal, vaginal and clitoral tissue are shown. The electrodes are formed from elastomeric material. Electrical stimulation to such areas is intended to control incontinence, to induce penile erection, or to induce excitation and orgasm. Three embodiments of a tube electrode formed from elastomeric material, have a nonconductive base (701, 752, 781), and a conductive tube (707, 758, 782) weaving through holes (705, 754, 783, 706, 756, 787) in the base. Two have single adjustable loops (710, 760) and are for use around penile or scotal tissue, and against anal tissue. The third comprises two loops (788, 789), one to wrap each testicle against scrotal tissue.
摘要翻译：显示用于刺激活组织如阴茎，阴囊，肛门，阴道和阴蒂组织的电极（700,750,780）。电极由弹性体材料形成。对这些区域的电刺激旨在控制失禁，诱发阴茎勃起，或诱导兴奋和性高潮。由弹性体材料形成的管电极的三个实施例具有非导电基底（701,752,781）和编织通孔（705,754,783,706,756,787）的导电管（707,758,782）在基地。两个具有单个可调环（710,760），可用于阴茎或组织组织和肛门组织周围。第三个包括两个环（788,789），一个将每个睾丸包裹在阴囊组织上。

70. 发明申请

WO1998018519A1 DEVICE FOR CARRYING OUT A TRANSOESOPHAGEAL ECHOCARDIOGRAPHY AND A CARDIOVERSION 审中-公开
标题翻译：执行转移性心电图和放射治疗的手段
公开(公告)号：WO1998018519A1
公开(公告)日：1998-05-07
申请号：PCT/FR1997001958
申请日：1997-10-31
申请人： BENHALIMA, Bouziane , LALAOUI, Zohra
IPC分类号： A61N01/05
CPC分类号： A61N1/0517 , A61N1/395
摘要： The invention concerns a device for carrying out a transoesophageal echocardiography and a cardioversion comprising a single endoscope (1) provided at its distal end with a ultrasonic sensor (3) and in the proximity of its distal end with at least en electrode (8) for generating electric shocks. The invention is useful for the treatment of auricular fibrillation.
摘要翻译：本发明涉及用于进行经食道超声心动图和心脏复律的装置，其包括在其远端处设置有超声波传感器（3）的单个内窥镜（1），并且在其远端附近至少具有电极（8），用于产生电击。本发明可用于治疗耳纤颤。

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