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61. 发明申请

WO2007008967A2 REMOTELY CONTROLLED CATHETER INSERTION SYSTEM 审中-公开
标题翻译：远程控制导管插入系统
公开(公告)号：WO2007008967A2
公开(公告)日：2007-01-18
申请号：PCT/US2006/027024
申请日：2006-07-11
申请人： CARDIAC INVENTIONS UNLIMITED, INC. , COHEN, Todd, J. , EILENBERG, Michael
发明人： COHEN, Todd, J. , EILENBERG, Michael
IPC分类号： A61M5/32
CPC分类号： A61M25/0105 , A61B34/30 , A61B2034/301 , A61M25/0133
摘要： A remotely controlled insertion system for a medical device is described. The system comprises a robotic device and a remote control mechanism. The robotic device has a handle controller to receive and hold the control handle or proximal end of a medical device. The medical device is capable of moving in up to six ranges of motion. In ione embodiment a first motor is connected through a drive screw to a handle controller to move the medical device forward and backward. A second motor is connected to drive wheels effective to rotate the medical device clockwise and counter clockwise. A third motor drives a series of gears that are connected to one or more control members on the medical device, this being effective to deflect a tip of the medical device so that movement of the third motor causes such deflection. A control unit is connected to all three motors.
摘要翻译：描述了用于医疗装置的远程控制插入系统。该系统包括机器人设备和远程控制机构。机器人装置具有手柄控制器以接收并保持控制手柄或医疗装置的近端。医疗设备能够移动多达六个范围的运动。在实施例中，第一电动机通过驱动螺杆连接到手柄控制器以向前和向后移动医疗装置。第二个电机连接到驱动轮，以有效地顺时针和逆时针旋转医疗设备。第三电机驱动连接到医疗装置上的一个或多个控制构件的一系列齿轮，这有效地偏转医疗装置的尖端，使得第三电机的运动引起这种偏转。控制单元连接到所有三个电机。

62. 发明申请

WO2005065280A2 REPAIR OF SPNAL ANNULAR DEFECTS AND ANNULO-NUCLEOPLASTY REGENERATION 审中-公开
标题翻译：血管内皮细胞损伤修复和神经母细胞再生
公开(公告)号：WO2005065280A2
公开(公告)日：2005-07-21
申请号：PCT/US2004/043455
申请日：2004-12-23
申请人： BIOMERIX CORPORATION , FRIEDMAN, Craig, D. , DATTA, Arindam
发明人： FRIEDMAN, Craig, D. , DATTA, Arindam
IPC分类号： A61B17/70
CPC分类号： A61F2/442 , A61B17/70 , A61F2/0095 , A61F2002/30062 , A61F2002/30064 , A61F2002/30072 , A61F2002/3008 , A61F2002/30579 , A61F2002/30677 , A61F2002/3092 , A61F2002/4435 , A61F2002/4445 , A61F2002/4677 , A61F2210/0004 , A61F2250/0098 , A61F2310/00365 , A61F2310/0097 , A61F2310/00976
摘要： The invention relates to the repair of spinal annular defects. An appartatus comprises a scaffold comprised of a biodurable, resiliently compressible, elastomeric reticulated composition to obliterate spinal/vertabral connective tissue defects, to obliterate spinal-annular nuclear tissue defects, and for spinal annulonucleoplasty regeneration. The apparatus comprises an at least partially cylindrical member.
摘要翻译：本发明涉及脊椎环形缺损的修复。配件包括由可生物量，弹性可压缩，弹性网状组合物构成的支架，以消除脊柱/垂体结缔组织缺陷，消除脊椎环状核组织缺陷，以及用于脊髓囊肿成形术再生。该装置包括至少部分圆柱形的构件。

63. 发明申请

WO2005031509A2 SYSTEM AND METHOD FOR CONTINUOUS DATA ANALYSIS OF AN ONGOING CLINICAL TRIAL 审中-公开
标题翻译：连续临床试验连续数据分析的系统与方法
公开(公告)号：WO2005031509A2
公开(公告)日：2005-04-07
申请号：PCT/US2004/030922
申请日：2004-09-22
申请人： MEDIDATA SOLUTIONS, INC. , IKEGUCHI, Edward, F. , DEVRIES, Glen, M. , SHERIF, Tarek, A.
发明人： IKEGUCHI, Edward, F. , DEVRIES, Glen, M. , SHERIF, Tarek, A.
IPC分类号： G06F
CPC分类号： G06Q50/24 , G06F19/00 , G06Q10/10 , G06Q50/22 , G16H10/20 , G16H50/70
摘要： System and method of continuously analyzing trial data of an ongoing clinical trial is provided. A statistical analysis is performed on a trial database containing subject trial data. If the result of the statistical analysis does not exceed a predetermined threshold value, then the statistical analysis is repeated while the clinical trial is ongoing. In a blinded clinical trial, a grouped database is generated from the trial database and blinding database prior to performing the statistical analysis. The grouped database groups the subject trial data according to the study groups. The ability to continuously monitor and analyze the trial data for statistical significance in tandem with data collection while the trial is ongoing provides many benefits to the researches because the trial database no longer becomes the bottleneck in obtaining useful results and statistical analysis can be conducted on a near real-time basis without having to wait until completion of the trial.
摘要翻译：提供了持续分析正在进行的临床试验的试验数据的系统和方法。对包含受试者数据的试验数据库进行统计分析。如果统计分析的结果不超过预定阈值，则在临床试验正在进行时重复统计分析。在盲症临床试验中，在进行统计分析之前，从试验数据库和盲法数据库生成分组数据库。分组数据库根据研究组对主体试验数据进行分组。在试验进行期间，连续监测和分析试验数据与数据收集相关的统计学意义的能力为研究提供了许多好处，因为试验数据库不再成为获得有用结果的瓶颈，统计分析可以在近乎实时的基础上，而不必等到审判完成。

64. 发明申请

WO2005016181A2 SHEATH WITH CHANNEL FOR ENDOSCOPE 审中-公开
标题翻译：带内窥镜通道的护套
公开(公告)号：WO2005016181A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/025238
申请日：2004-08-04
申请人： VISION-SCIENCES, INC. , MARTONE, Stephen , HADANI, Ron
发明人： MARTONE, Stephen , HADANI, Ron
IPC分类号： A61F
CPC分类号： A61B1/012 , A61B1/00135 , A61B1/0014 , A61B1/00142 , A61B1/015 , A61B1/018 , A61B46/10 , A61B46/13
摘要： A sheath assembly for an invasive probe. The sheath assembly includes an internal sheath for covering a probe and at least one channel tube external to the internal sheath, the channel tube being foldable into a closed state in which the tube does not define a channel, or openable into an open state in which the tube defines a channel that extends along a portion of the sheath assembly.
摘要翻译：
用于侵入式探针的护套组件。护套组件包括用于覆盖探针的内部护套和位于内部护套外部的至少一个通道管，通道管可折叠成关闭状态，其中管不限定通道，或者可打开成打开状态，其中管限定了沿护套组件的一部分延伸的通道。

65. 发明申请

WO2004080533A1 APPARATUS AND METHOD FOR DELIVERING ELECTRICAL SIGNALS TO MODIFY GENE EXPRESSION IN CARDIAC TISSUE 审中-公开
标题翻译：提供电信号改变心脏组织中基因表达的装置和方法
公开(公告)号：WO2004080533A1
公开(公告)日：2004-09-23
申请号：PCT/US2004/007589
申请日：2004-03-10
申请人： IMPULSE DYNAMICS NV , MIKA, Yuval , SABBAH, Hani , HADDAD, Walid , ROUSSO, Benny
发明人： MIKA, Yuval , SABBAH, Hani , HADDAD, Walid , ROUSSO, Benny
IPC分类号： A61N1/00
CPC分类号： A61N1/0587 , A61N1/326 , A61N1/362 , A61N1/3627 , A61N1/36557
摘要： Method and apparatus (120) for modifying gene expression in cardiac muscle cells (110), by the application of electric fields.
摘要翻译：用于通过施加电场来改变心肌细胞（110）中的基因表达的方法和装置（120）。

66. 发明申请

WO2004032596A2 RINGED FORCEPS 审中-公开
标题翻译：结合力
公开(公告)号：WO2004032596A2
公开(公告)日：2004-04-22
申请号：PCT/US2003/032084
申请日：2003-10-08
申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK , TREAT, Michael, R.
发明人： TREAT, Michael, R.
IPC分类号： A61B17/00 , A61B17/072 , A61B17/125 , A61B17/32 , A61B18/04 , A61B18/08 , A61B18/14 , A61B18/20 , A61F7/00 , B32B27/08
CPC分类号： A61B17/072 , A61B10/02 , A61B17/32 , A61B17/320068 , A61B18/085 , A61B18/1445 , A61B18/20 , A61B2017/00734 , A61B2017/07214 , A61B2018/00083 , A61B2018/00095 , A61B2018/0022 , A61B2018/00595 , A61B2018/00601 , A61B2018/0063 , A61B2018/00666 , A61B2018/00684 , A61B2018/00761 , A61B2018/00886 , A61B2018/0091 , A61B2018/1462 , A61B2018/1861 , A61B2090/064 , A61F2007/0078 , B32B27/08 , Y10T428/249981 , Y10T428/249984 , Y10T428/249985 , Y10T428/31544
摘要： A surgical instrument comprises two oppositely-positioned working numbers each having proximal and distal ends and each having a working surface. The instrument also comprises at least one ring member affixed to a least one of the working members to encompass one or more of a user's fingers. In one embodiment at least one working surface has a heating element to cut or seal and cut tissue.
摘要翻译：手术器械包括两个相对位置的工作号码，每个工作号码具有近端和远端，并且每个具有工作表面。仪器还包括固定到至少一个工作构件的至少一个环构件以包围使用者的手指中的一个或多个。在一个实施例中，至少一个工作表面具有用于切割或密封和切割组织的加热元件。

67. 发明申请

WO2003086714A2 ROBOTIC SCRUB NURSE 审中-公开
标题翻译：机器人护理
公开(公告)号：WO2003086714A2
公开(公告)日：2003-10-23
申请号：PCT/US2003/010781
申请日：2003-04-07
申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , TREAT, Michael, R. , LICHTMAN, Martin, T. , BRADY, David, M.
发明人： TREAT, Michael, R. , LICHTMAN, Martin, T. , BRADY, David, M.
IPC分类号： B25J
CPC分类号： A61B90/96 , A61B17/54 , A61B34/30 , A61B34/70 , A61B90/92 , A61B2017/00203
摘要： A robotic system, and corresponding method, performs the function of a human scrub technician in an operating room. The present invention is directed to a device, and associated method for using the device, which performs one, or more, of the following functions: instrument identification, instrument localization, instrument handling, interaction with a human, and integration of functions through a cognitive system. A method for movement of the device comprises the steps of modeling the arm of the robot to create a model comprising elements of finite mass joined by junctions, using an algorithm to calculate results of the effect of applying force to the elements of the model, using attractive, replusive and postural forces in the algorithm, and using the results of the model to direct motion of the device.
摘要翻译：机器人系统和相应的方法在手术室中执行人类擦洗技术人员的功能。本发明涉及一种用于使用该装置的装置和相关方法，该装置执行以下功能中的一种或多种：仪器识别，仪器定位，仪器处理，与人的相互作用，以及通过认知的功能的整合系统。一种用于移动装置的方法包括以下步骤：对机器人的臂进行建模，以创建包括由连接点连接的有限质量元素的模型，使用算法来计算对模型的元件施加力的效果的结果，使用在算法中有吸引力的，重复的和姿态的力，并使用模型的结果来引导设备的运动。

68. 发明申请

WO2003066125A3 SINGLE ACCESS DIALYSIS NEEDLE 审中-公开
公开(公告)号：WO2003066125A3
公开(公告)日：2003-08-14
申请号：PCT/US2003/003392
申请日：2003-02-05
申请人： YALE UNIVERSITY , TAL, Michael
发明人： TAL, Michael
IPC分类号： A61M29/00
摘要： A single access dialysis needle system comprises a first cannula (40), a second cannula or sheath (44), and a barrier (50) arranged on the outer surface of the first cannula (40). The distal end of the first cannula (40) extends distal to the distal end of the second cannula or outer sheath (44) and the barrier (50) is positioned between the respective distal ends. When the barrier (50) is inflated or otherwise activated, it prevents or minimizes recirculation.

69. 发明申请

WO2003066125A2 SINGLE ACCESS DIALYSIS NEEDLE 审中-公开
标题翻译：单次接触透析针
公开(公告)号：WO2003066125A2
公开(公告)日：2003-08-14
申请号：PCT/US2003/003392
申请日：2003-02-05
申请人： YALE UNIVERSITY , TAL, Michael
发明人： TAL, Michael
IPC分类号： A61M
CPC分类号： A61M25/0606 , A61M1/3653 , A61M1/3659 , A61M1/3661 , A61M25/04 , A61M2025/0031 , A61M2025/0037 , A61M2025/0039 , A61M2025/1052
摘要： A single access dialysis needle system comprises a first cannula, a second cannula or sheath, and a barrier arranged on the outer surface of the first cannula. The distal end of the first cannula extends distal to the distal end of the second cannula or outer sheath, and the barrier is positioned between the respective distal ends. When the barrier is inflated or otherwise activated, it prevents or minimizes recirculation.
摘要翻译：单次进入透析针系统包括第一套管，第二套管或护套以及布置在第一插管的外表面上的屏障。第一插管的远端延伸到第二插管或外护套的远端的远侧，并且屏障位于相应的远端之间。当屏障膨胀或以其他方式激活时，可防止或最小化再循环。

70. 发明申请

WO2003057272A2 VASCULAR ACCESS DEVICE 审中-公开
标题翻译：血管通路装置
公开(公告)号：WO2003057272A2
公开(公告)日：2003-07-17
申请号：PCT/US2002/041371
申请日：2002-12-24
申请人： YALE UNIVERSITY , TAL, Michael
发明人： TAL, Michael
IPC分类号： A61M
CPC分类号： A61M25/0606 , A61M25/0662 , A61M25/0693 , A61M29/00 , A61M2025/0687
摘要： A vascular access system comprises a needle having a distal tip and a proximal fitting section and a dilator having a solid distal section connected to a solid proximal section and an annular recess therebetween, the dilator having a passageway so that the dilator is coaxially positioned around the needle. The needle has at least one opening positioned proximal to its distal tip so that, when the distal end of the needle enters a blood vessel, blood enters the annular recess to show the operator that access has been achieved. Optionally, a sheath having a distal tip, a proximal fitting section, and a lumen sufficient to coaxially fit over the dilator.
摘要翻译：血管通路系统包括具有远侧末端和近侧配合部分的针，以及具有连接到固体近端部分的实心远端部分和其间的环形凹部的扩张器，所述扩张器具有通道，使得扩张器同轴地位于针。针具有至少一个位于其远侧末端附近的开口，使得当针的远端进入血管时，血液进入环形凹部以向操作者显示已经实现进入。可选地，护套具有远侧末端，近侧配合部分和足以同轴配合在扩张器上的内腔。

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