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51. 发明申请

WO2013162613A1 ELECTROCARDIOGRAM PACE PULSE DETECTION AND ANALYSIS 审中-公开
标题翻译：电光脉冲检测和分析
公开(公告)号：WO2013162613A1
公开(公告)日：2013-10-31
申请号：PCT/US2012/035647
申请日：2012-04-27
申请人： DRAEGER MEDICAL SYSTEMS, INC. , LALL, Carolyn Anjali , CHEN, Yu
发明人： LALL, Carolyn Anjali , CHEN, Yu
IPC分类号： A61B5/0452 , G06K9/00 , A61N1/08
CPC分类号： A61B5/7217 , A61B5/0006 , A61B5/04017 , A61B5/044 , A61B5/0452 , A61B5/04525 , A61B5/7246 , A61N1/37 , A61N1/3706
摘要： Data is received characterizing an electrocardiogram (ECG) measured from a patient having a pacemaker. The pacemaker can intermittently provide a pace to a heart of the patient. By comparing at least a portion of the received data to a template a pace pulse can be detected from at least a portion of the received data. The template comprises one or more pace pulses measured from the patient. The template is modified, at least in part, by the detected pace pulse to update the template. Data characterizing the detected pace pulse is provided. Related apparatus, systems, techniques and articles are also described.
摘要翻译：数据被接收，表征从具有起搏器的患者测量的心电图（ECG）。起搏器可以间断地为患者的心脏提供一个步伐。通过将接收到的数据的至少一部分与模板进行比较，可以从接收到的数据的至少一部分检测起搏脉冲。模板包括从患者测量的一个或多个起搏脉冲。该模板至少部分地通过检测到的起搏脉冲进行修改，以更新模板。提供表征检测到的起搏脉冲的数据。还描述了相关设备，系统，技术和物品。

52. 发明申请

WO2013020270A1 A LIGHT-TIGHT AND COLLAPSIBLE CHAMBER FOR DEMONSTRATING THE OPTICAL PERFORMANCE OF REFLECTIVE MATERIALS 审中-公开
标题翻译：用于演示反射材料的光学性能的轻型和可折叠室
公开(公告)号：WO2013020270A1
公开(公告)日：2013-02-14
申请号：PCT/CN2011/078153
申请日：2011-08-09
申请人： 3M INNOVATIVE PROPERTIES COMPANY , GUO, Bo , CHEN, Rui , SHI, Weilin , LI, Xiaoxian , ZHU, Yongping , CHEN, Yu , ZHENG, Lingbo , SHEN, Ying , GU, Shaoqing , SHAO, Yichun
发明人： GUO, Bo , CHEN, Rui , SHI, Weilin , LI, Xiaoxian , ZHU, Yongping , CHEN, Yu , ZHENG, Lingbo , SHEN, Ying , GU, Shaoqing , SHAO, Yichun
IPC分类号： A45C15/00 , G02B7/00 , G03D17/00
CPC分类号： G02B5/12 , A45C3/001 , A45C3/02 , A45C9/00
摘要： A light-tight and collapsible chamber (120, 300) for use in demonstrating the optical performance of a piece of retroreflective sheeting placed within the chamber (120, 300) is provided. The chamber (120, 300) comprises a generally opaque polygonal back panel (130, 320) having a plurality of edges; a plurality of generally opaque side panels (140, 170) wherein adjacent side panels (140, 170) are attached to one another to form a light-tight connection and each of the plurality of opaque side panels (140, 170) are attached along and positioned essentially perpendicular to one of the plurality of edges of the back panel (130, 320) to form a light-tight connection; and an open area (150, 330) essentially parallel to and distanced from the back panel (130, 320) and forming an observation window permitting an observer to view the piece of retroreflective sheeting positioned within the chamber (120, 300). In one embodiment, the chamber (120, 300) further comprises a leaflet (310) capable of attaching to the piece of retroreflective sheeting attached to the back panel (130, 320). In another embodiment, the chamber (120, 300) can be collapsed in various ways.
摘要翻译：提供了用于证明放置在腔室（120,300）内的一片回射片材的光学性能的不透光和可折叠腔室（120,300）。腔室（120,300）包括具有多个边缘的大致不透明的多边形后面板（130,320）; 多个通常不透明的侧板（140,170），其中相邻的侧板（140,170）彼此附接以形成不透光连接，并且所述多个不透明侧板（140,170）中的每一个沿着并且基本上垂直于后面板（130,320）的多个边缘中的一个定位，以形成不透光的连接; 以及基本上平行于所述后面板（130,320）并远离的开放区域（150,330），并且形成允许观察者观察位于所述腔室（120,300）内的所述回射片材的观察窗口。在一个实施例中，腔室（120,300）还包括能够附接到附接到后面板（130,320）的一片后向反射片材的小叶片（310）。在另一个实施例中，腔室（120,300）可以以各种方式折叠。

53. 发明申请

WO2012149207A1 OSCILLOMETRIC NON-INVASIVE BLOOD PRESSURE MEASUREMENTS IN PATIENTS EXPERIENCING ABNORMAL HEARTBEATS 审中-公开
标题翻译：患者经手术治疗异常心脏病的无效无血压测量
公开(公告)号：WO2012149207A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/035282
申请日：2012-04-26
申请人： DRAEGER MEDICAL SYSTEMS, INC. , CHEN, Yu , EL-GHOUCH, Mohamad, M. , ZHANG, Zhe
发明人： CHEN, Yu , EL-GHOUCH, Mohamad, M. , ZHANG, Zhe
IPC分类号： A61B5/0452 , A61B5/022
CPC分类号： A61B5/02225 , A61B5/02028 , A61B5/02116 , A61B5/04012 , A61B5/0408 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0472 , G06F19/00
摘要： Disclosed is a method for implementation by one or more data processors including acquiring noninvasive blood pressure data using an inflatable cuff applied around a portion of a patient by inflating the cuff to a pressure above the patient's systolic blood pressure, and detecting a first oscillation pulse within the cuff during a deflation step. The method also includes acquiring electrocardiogram (ECG) data from the patient by detecting an ECG waveform corresponding to a first heartbeat using an ECG lead coupled to the patient, classifying the ECG waveform as normal or not normal, aligning, the first oscillation pulse to the ECG waveform corresponding to the first heartbeat if the ECG waveform is classified normal or rejecting the first oscillation pulse if the ECG waveform is classified not normal, and calculating the blood pressure using the aligned first oscillation pulse. Related apparatus, systems, methods and/or articles are described.
摘要翻译：公开了一种用于由一个或多个数据处理器实现的方法，包括使用通过将袖带膨胀到高于患者的收缩压的压力的周围的患者的一部分周围施加的可膨胀的袖带来获取无创血压数据，并且检测第一振荡脉冲在通缩步骤期间的袖口。该方法还包括通过使用耦合到患者的ECG导联检测对应于第一心跳的ECG波形来从患者获取心电图（ECG）数据，将ECG波形分类为正常或不正常，将第一振荡脉冲对准如果ECG波形被分类为正常，则将ECG波形对应于第一心跳，如果ECG波形被分类为不正常则排除第一振荡脉冲，并且使用对准的第一振荡脉冲计算血压。描述了相关装置，系统，方法和/或制品。

54. 发明申请

WO2012137079A2 METHOD AND APPARATUS FOR ACCESSING IN AN EQUIPMENT OF A COMMUNICATION NETWORK 审中-公开
标题翻译：用于接入通信网络设备的方法和装置
公开(公告)号：WO2012137079A2
公开(公告)日：2012-10-11
申请号：PCT/IB2012/000905
申请日：2012-03-30
申请人： ALCATEL LUCENT , CHEN, Yu , WANG, He , DU, Hongfei
发明人： CHEN, Yu , WANG, He , DU, Hongfei
CPC分类号： H04W72/042 , H04L1/1812 , H04L1/1887 , H04L1/1896 , H04L5/0044 , H04L5/0062
摘要： A method of accessing in an equipment of a communication network is proposed in the invention. The method comprises the steps of: receiving a message 2 from a base station, the message 2 being used for an assignment of resource to transmit a message 3, the assigned resource corresponding to N HARQ RTTs, where 1≤N≤8; and transmitting the message 3 only in part of the N HARQ RTTs. With the scheme of the invention, a MTC device selectively transmits the Msg3 in one/some HARQ RTT and maintains silence in another one/some HARQ RTT, thus the possibility of the occurrence of access collision with other UEs may be backed off, such that other UEs, particularly human-to-human UEs, may transmit the Msg3 normally. And the possibility of the occurrence of collision is reduced from the viewpoint of the user equipments in a network, reducing entirely the possibility of an access delay and access failure.
摘要翻译：本发明提出了一种在通信网络的设备中进行访问的方法。该方法包括以下步骤：从基站接收消息2，消息2用于分配资源以发送消息3，所分配的资源对应于N个HARQ RTT，其中1 = N = 8; 并且仅在N个HARQ RTT的一部分中发送消息3。利用本发明的方案，MTC设备选择性地在一个/某个HARQ RTT中发送Msg3，并且在另一个/一些HARQ RTT中保持静默，因此可能会退出与其他UE发生访问冲突的可能性，使得其他UE，特别是人对人类UE可以正常地发送Msg3。并且，从网络中的用户设备的观点来看，发生冲突的可能性降低，从而完全减少了访问延迟和访问失败的可能性。

55. 发明申请

WO2012096832A2 HDAC INHIBITING DERIVATIVES OF CAMPTOTHECIN 审中-公开
标题翻译： HDAC抑制CAMPTOTHECIN的衍生物
公开(公告)号：WO2012096832A2
公开(公告)日：2012-07-19
申请号：PCT/US2012/020398
申请日：2012-01-06
申请人： CRYSTAL BIOPHARMACEUTICAL LLC , CHEN, Yi , CHEN, Yu
发明人： CHEN, Yi , CHEN, Yu
IPC分类号： C07D498/22 , C07D471/04 , C07D491/04 , A61K31/4741 , A61P35/00
CPC分类号： C07D491/22 , A61K31/4745 , A61K31/496 , A61K31/506 , A61K31/695 , A61K45/06 , C07F7/10 , Y02A50/414
摘要： The disclosure includes hydroxamic compounds of Formula I: (Formula I) wherein Z, L, R 1 , R 2 , and R 3 are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
摘要翻译：本公开内容包括式I的异羟肟酸化合物：式（I）其中Z，L，R 1，R 2和R 3在本文中定义。还公开了用这些化合物治疗肿瘤疾病或免疫疾病的方法。

56. 发明申请

WO2012020311A2 METHOD AND APPARATUS FOR MANAGING MULTIMEDIA BROADCAST MULTICAST SERVICE MBMS TRANSMISSION 审中-公开
标题翻译：用于管理多媒体广播多播服务MBMS传输的方法和设备
公开(公告)号：WO2012020311A2
公开(公告)日：2012-02-16
申请号：PCT/IB2011/002070
申请日：2011-07-29
申请人： ALCATEL LUCENT , CHEN, Yu
发明人： CHEN, Yu
IPC分类号： H04W4/06
CPC分类号： H04W4/06
摘要： The present invention discloses a method and apparatus for managing multimedia broadcast multicast service MBMS transmission, wherein a plurality of base stations simultaneously transmit MBMS via a single frequency. The method comprises the step of: switching off MBMS transmission of at least one base station among the plurality of base stations. According to the present invention, the system power can be saved.
摘要翻译：本发明公开了一种管理多媒体广播多播业务MBMS传输的方法和装置，其中多个基站通过单一频率同时传输MBMS。该方法包括以下步骤：关闭多个基站中的至少一个基站的MBMS传输。根据本发明，可以节省系统功率。

57. 发明申请

WO2011128685A2 CONTROL OF A BRUSHLESS MOTOR 审中-公开
标题翻译：无刷电机的控制
公开(公告)号：WO2011128685A2
公开(公告)日：2011-10-20
申请号：PCT/GB2011/050732
申请日：2011-04-13
申请人： DYSON TECHNOLOGY LIMITED , CHEN, Yu , CELIK, Tuncay , GREETHAM, Stephen
发明人： CHEN, Yu , CELIK, Tuncay , GREETHAM, Stephen
CPC分类号： H02P6/085 , H02P6/15 , H02P6/26 , H02P2209/07
摘要： A method of controlling a brushless motor, the method comprising rectifying an alternating voltage to provide a rectified voltage, and exciting a winding of the motor with the rectified voltage. The winding is excited in advance of predetermined rotor positions by an advance period that is updated in response to a zero-crossing in the alternating voltage. Additionally, a control system that implements the method, and a motor system that incorporates the control system.
摘要翻译：一种控制无刷电动机的方法，所述方法包括对交流电压进行整流以提供整流电压，以及激励具有整流电压的电动机的绕组。绕组在预定的转子位置之前被提前期间激励，该提前期响应于交流电压中的过零而更新。另外，实现该方法的控制系统以及并入控制系统的电机系统。

58. 发明申请

WO2009108745A1 STRUCTURE OF A PROTEIN PHOSPHATASE 2A HOLOENZYME: INSIGHTS INTO TAU DEPHOSPHORYLATION 审中-公开
标题翻译：蛋白磷酸化酶2A霍乱病毒的结构：沉积物中的沉积物
公开(公告)号：WO2009108745A1
公开(公告)日：2009-09-03
申请号：PCT/US2009/035221
申请日：2009-02-26
申请人： THE TRUSTEES OF PRINCETON UNIVERSITY , SHI, Yigong , CHEN, Yu , XU, Yanhui
发明人： SHI, Yigong , CHEN, Yu , XU, Yanhui
IPC分类号： A61K38/46 , C12N9/16 , C12Q1/42 , G01N33/573 , G06F17/50
CPC分类号： C12N9/16 , C12Y301/03016 , G01N2333/916 , Y02A90/26
摘要： Embodiments of the present invention relate to crystals and atomic coordinates for PP2A, as well as methods for using these atomic coordinates to prepare modulators of PP2A and inhibitors prepared using such methods. Further embodiments relate to biochemical analyses of the interactions of PP2A alone or in complex with Tau. Further embodiments relate to compositions including mimetics and small molecules, optionally, secondary agents, which may be used to treat disorders in which PP2A activity and/or Tau plays a contributing role.
摘要翻译：本发明的实施方案涉及PP2A的晶体和原子坐标，以及使用这些原子坐标来制备PP2A的调节剂的方法和使用这些方法制备的抑制剂。其他实施方案涉及单独的PP2A或与Tau复合物的相互作用的生物化学分析。另外的实施方案涉及包括模拟物和小分子（任选地，第二试剂）的组合物，其可以用于治疗PP2A活性和/或Tau起作用的病症。

59. 发明申请

WO2007149097A1 ANIMALS, CELLS AND METHODS FOR PRODUCTION OF DETECTABLY-LABELED ANTIBODIES 审中-公开
标题翻译：动物，细胞和生产检测标签抗体的方法
公开(公告)号：WO2007149097A1
公开(公告)日：2007-12-27
申请号：PCT/US2006/024592
申请日：2006-06-23
申请人： THE ROCKEFELLER UNIVERSITY , SIMON, Sanford, M. , CHEN, Yu
发明人： SIMON, Sanford, M. , CHEN, Yu
IPC分类号： A01K67/027
CPC分类号： A01K67/0275 , A01K2217/072 , A01K2227/105 , A01K2267/01 , C07K16/00 , C07K2317/92 , C07K2319/60 , C07K2319/70 , C12N5/163 , C12N2510/02 , C12N2517/02
摘要： Genetically-modified non-human mammals and immune cells are provided which are capable of producing or secreting detectably-labeled immunoglobulin molecules as a result of genetic modifications of at least one immunoglobulin gene in the genome thereof, such that a fusion polynucleotide encoding a detectable protein or peptide and an immunoglobulin component molecule is present.
摘要翻译：提供了遗传修饰的非人哺乳动物和免疫细胞，其能够由于在其基因组中的至少一个免疫球蛋白基因的遗传修饰而产生或分泌可检测标记的免疫球蛋白分子，使得编码可检测蛋白质的融合多核苷酸或肽和免疫球蛋白组分分子存在。

60. 发明申请

WO2007050040A1 IMMOBILIZATION UNIT AND DEVICE FOR ISOLATION OF NUCLEIC ACID MOLECULES 审中-公开
标题翻译：固定单元和用于分离核酸分子的装置
公开(公告)号：WO2007050040A1
公开(公告)日：2007-05-03
申请号：PCT/SG2005/000374
申请日：2005-10-28
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , NATIONAL UNIVERSITY OF SINGAPORE , JI, Hongmiao , YOBAS, Levent , CHEN, Yu , HUI, Wing Cheong , HENG, Chew Kiat , LIM, Tit Meng
发明人： JI, Hongmiao , YOBAS, Levent , CHEN, Yu , HUI, Wing Cheong , HENG, Chew Kiat , LIM, Tit Meng
IPC分类号： C12Q1/68 , C12N15/00 , G01N33/50 , C12M1/40 , G01N33/48
CPC分类号： B01F5/0647 , B01F5/0646 , B01F13/0059 , B01L3/502746 , B01L2200/0631 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2400/0487 , G01N1/34 , G01N1/405
摘要： An immobilization unit (820) for the detection of dexoyribonucleic acid (DNA) and ribonucleic acid (RNA) molecules capable of immobilizing nucleic molecules, said immobilization unit comprising a channel of a given depth, width and length and having at least one surface. The surface is adapted to immobilize nucleic molecules under suitable conditions. The channel has at least one straight portion and at least one meandering portion. The at least one meandering portion is essentially u-shaped and the at least one straight portion is an arm of the u-shaped meandering portion.
摘要翻译：一种用于检测能够固定核酸分子的核酸核酸（DNA）和核糖核酸（RNA）分子的固定单元（820），所述固定单元包括给定深度，宽度和长度的通道，并具有至少一个表面。表面适于在合适的条件下固定核酸分子。通道具有至少一个直线部分和至少一个曲折部分。至少一个曲折部分基本上是U形的，并且至少一个直线部分是U形曲折部分的臂。

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