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41. 发明申请

WO2008083069A2 BIOERODIBLE NANO-FIBROUS AND NANO-POROUS CONDUCTIVE COMPOSITES 审中-公开
标题翻译：可生物降解的纳米纤维和纳米多孔导电复合材料
公开(公告)号：WO2008083069A2
公开(公告)日：2008-07-10
申请号：PCT/US2007/088533
申请日：2007-12-21
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , FENG, James Q. , WEBER, Jan , SHIPPY III, James Lee
发明人： ATANASOSKA, Liliana , FENG, James Q. , WEBER, Jan , SHIPPY III, James Lee
IPC分类号： A61L27/44 , A61L27/50 , A61L27/54 , A61L27/58 , A61L29/12 , A61L29/14 , A61L29/16 , A61L31/12 , A61L31/14 , A61L31/16
CPC分类号： A61L27/40 , A61L27/14 , A61L27/50 , A61L27/58 , A61L2400/12
摘要： A bioerodible conductive tissue scaffold that can provide, e.g., improved tissue growth.
摘要翻译：可以提供例如改善的组织生长的生物蚀蚀性导电组织支架。

42. 发明申请

WO2008036549A3 MEDICAL DEVICES 审中-公开
公开(公告)号：WO2008036549A3
公开(公告)日：2008-03-27
申请号：PCT/US2007/078412
申请日：2007-09-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , WEBER, Jan , LARSEN, Steven R. , WARNER, Robert W.
发明人： ATANASOSKA, Liliana , WEBER, Jan , LARSEN, Steven R. , WARNER, Robert W.
IPC分类号： A61F2/90 , A61L31/02 , A61L31/10 , A61L31/14
摘要： Medical devices are described that include a device body that carries a first bioerodible member and a second bioerodible member. One of the first or second members includes a bioerodible metallic material or ceramic, and the other includes a bioerodible polymeric material. The first and/or second member can include a therapeutic agent such as paclitaxel.

43. 发明申请

WO2008036357A2 MEDICAL DEVICES HAVING BIODEGRADABLE POLYMERIC REGIONS WITH OVERLYING HARD, THIN LAYERS 审中-公开
标题翻译：具有生物可降解聚合物区域的医疗设备，具有硬度较薄的层
公开(公告)号：WO2008036357A2
公开(公告)日：2008-03-27
申请号：PCT/US2007/020368
申请日：2007-09-20
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan
发明人： WEBER, Jan
IPC分类号： A61L31/14 , A61L31/16 , A61L31/08
CPC分类号： A61L31/148 , A61L31/084 , A61L31/088
摘要： Implantable or insertable medical devices comprising a biodegradable polymeric region and a hard, thin layer disposed over the biodegradable polymeric region are described. Also described are methods for creating the same.
摘要翻译：描述了包括可生物降解的聚合物区域和设置在可生物降解的聚合物区域上方的硬的薄层的可植入或可插入的医疗装置。还描述了创建它们的方法。

44. 发明申请

WO2008033711A2 MEDICAL DEVICES WITH DRUG-ELUTING COATING 审中-公开
标题翻译：医疗设备与药物涂层涂层
公开(公告)号：WO2008033711A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/077711
申请日：2007-09-06
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , MILLER, Matthew
发明人： WEBER, Jan , MILLER, Matthew
IPC分类号： A61F2/00 , A61F2/90 , B23K26/38 , A61L31/08
CPC分类号： A61F2/06 , A61F2/82 , A61F2/91 , A61F2002/30322 , A61F2210/0076 , A61F2230/0054 , A61F2250/0026 , A61F2250/0056 , A61F2250/0068 , A61F2310/00389 , A61L31/082 , A61L31/10 , A61L31/16 , A61L2300/608 , Y10T29/49826
摘要： Medical devices, such as endoprostheses, and methods of making the devices are described. In one embodiment, a medical device having a body of interconnected bands and connectors forming an elongated tubular structure having an inner luminal wall surface, an outer abluminal wall surface and a side wall surface, and defining a central lumen or passageway, wherein said inner luminal wall surface and side wall surface of the bands and connectors form transverse passageways through the elongated tubular structure is described. One or more wall surfaces of the tubular structure can bear a coating whose selected regions define at least one depression. The coating can further include at least one biologically active substance.
摘要翻译：描述医疗设备，如内窥镜假体，以及制造设备的方法。在一个实施方案中，医疗装置具有相互连接的带和连接器本体，形成具有内腔壁表面，外腔外壁表面和侧壁表面的细长管状结构，并且限定中央内腔或通道，其中所述内腔描述了带和连接器的壁表面和侧壁表面形成穿过细长管状结构的横向通道。管状结构的一个或多个壁表面可以承载涂层，其选定区域限定至少一个凹陷。该包衣可以进一步包含至少一种生物活性物质。

45. 发明申请

WO2008033546A2 IMPLANTABLE ELECTRODES WITH POLYOXOMETALATES 审中-公开
标题翻译：可聚电极与聚氧乙烯醚
公开(公告)号：WO2008033546A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/020081
申请日：2007-09-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana, L. , WEBER, Jan , HASTINGS, Roger, N. , WARNER, Robert, W. , POLKINGHORNE, Jeannette, C.
发明人： ATANASOSKA, Liliana, L. , WEBER, Jan , HASTINGS, Roger, N. , WARNER, Robert, W. , POLKINGHORNE, Jeannette, C.
CPC分类号： A61N1/05 , A61N1/056
摘要： An electrode with an electrode surface having a polyoxometalate (POM). The use of POM with an electrode surface increases the active electrochemical surface area, with a resulting increase in capacitance and impedance, and a decrease of polarization losses at the electrode/tissue interface. In addition, electrodes having POM can include pseudo-capacitive properties from their redox properties and charge storage properties.
摘要翻译：具有电极表面的具有多金属氧酸盐（POM）的电极。使用具有电极表面的POM增加了活性电化学表面积，导致电容和阻抗的增加以及电极/组织界面处极化损失的减小。此外，具有POM的电极可以包括其氧化还原性质和电荷存储性质的伪电容性质。

46. 发明申请

WO2008030383A3 MEDICAL DEVICES HAVING NANOSTRUCTURED COATING FOR MACROMOLECULE DELIVERY 审中-公开
公开(公告)号：WO2008030383A3
公开(公告)日：2008-03-13
申请号：PCT/US2007/019092
申请日：2007-08-30
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , WEBER, Jan , WARNER, Robert, W. , ZOROMSKI, Michele
发明人： ATANASOSKA, Liliana , WEBER, Jan , WARNER, Robert, W. , ZOROMSKI, Michele
IPC分类号： A61L27/28 , A61L27/58 , A61L31/08 , A61L31/14
摘要： A medical device having a biodegradable coating comprising an inorganic material complexed to macromolecules. Biodegradation of the biodegradable coating releases nanoparticles of the inorganic material with macromolecules complexed to the released nanoparticles. The inorganic material may be applied directly onto the medical device as a nanostructured coating or be dispersed within or under a layer of biodegradable polymer. The medical device body may comprise a biodegradable metallic material. Also provided is a method of delivering macromolecules to body tissue using the medical device of the present invention.

47. 发明申请

WO2007123627A1 MEDICAL BALLOONS 审中-公开
标题翻译：医用气球
公开(公告)号：WO2007123627A1
公开(公告)日：2007-11-01
申请号：PCT/US2007/007433
申请日：2007-03-26
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HORN, Daniel, J. , WEBER, Jan , BLIX, John , TOMASCHKO, Daniel, K. , SCHEWE, Scott , GUNDERSON, Richard, C. , VOLK, Angela, K. , CHEN, John, Jianhua
发明人： HORN, Daniel, J. , WEBER, Jan , BLIX, John , TOMASCHKO, Daniel, K. , SCHEWE, Scott , GUNDERSON, Richard, C. , VOLK, Angela, K. , CHEN, John, Jianhua
IPC分类号： A61M25/10 , A61M29/02 , A61L29/08 , A61L29/12
CPC分类号： A61M25/10 , A61L29/085 , A61L29/123 , A61L29/126 , A61M25/1029 , A61M25/1038 , A61M2025/1031 , A61M2025/1075 , A61M2025/1088
摘要： Described herein are medical balloons which contain one or more material regions that are configured to cause the balloons to preferentially fold into predetermined orientations upon deflation.
摘要翻译：这里描述的是包含一个或多个材料区域的医疗气囊，其被构造成使得气囊在放气时优先折叠成预定取向。

48. 发明申请

WO2007098353A2 BIOERODIBLE ENDOPROSTHESES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：可生物降解的内生物及其制备方法
公开(公告)号：WO2007098353A2
公开(公告)日：2007-08-30
申请号：PCT/US2007/062178
申请日：2007-02-15
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , ATANASOSKA, Liliana , KONDYURIN, Alexey
发明人： WEBER, Jan , ATANASOSKA, Liliana , KONDYURIN, Alexey
CPC分类号： A61L31/148 , A61L31/084 , A61L2400/18
摘要： Endoprostheses include a wall having a base, e.g., a bioerodible base, and a polymer that may include a region of carbonized polymer formed by implantation.
摘要翻译：内用假体包括具有基底例如生物可蚀解基质的壁和可以包括通过注入形成的碳化聚合物区域的聚合物。

49. 发明申请

WO2007024616A2 RESONATOR WITH ADJUSTABLE CAPACITOR FOR MEDICAL DEVICE 审中-公开
标题翻译：具有用于医疗装置的可调节电容器的共振器
公开(公告)号：WO2007024616A2
公开(公告)日：2007-03-01
申请号：PCT/US2006/032108
申请日：2006-08-17
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan
发明人： WEBER, Jan
IPC分类号： A61F2/82
CPC分类号： G01R33/286 , A61B5/055 , A61F2/82 , G01R33/3628 , Y10T29/49117
摘要： An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a conductive member, a sleeve having first and second sockets that receive at least portions of the inductor coil and the conductive member as electrodes to provide a capacitor structure. Dielectric material can be positioned between at least the first and second sockets, where changes in the cross sectional area defined by the induction coil cause changes in the capacitance value (C) as one or more of the electrodes move within the socket. Changes in the inductance and the capacitance values allow for the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system.
摘要翻译：具有可调电容器的谐振器装置的装置，系统和方法，用于允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。谐振器装置包括电感线圈，导电构件，具有第一和第二插座的套筒，该套管至少容纳电感器线圈和导电构件的至少一部分作为电极以提供电容器结构。介电材料可以位于至少第一和第二插座之间，其中由感应线圈限定的横截面积的变化引起电容值（C）的变化，因为一个或多个电极在插座内移动。电感和电容值的变化允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。

50. 发明申请

WO2006130317A1 ENDOPROSTHESES 审中-公开
标题翻译：用假体
公开(公告)号：WO2006130317A1
公开(公告)日：2006-12-07
申请号：PCT/US2006/017984
申请日：2006-05-08
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan
发明人： WEBER, Jan
IPC分类号： A61F2/06 , A61L31/18
CPC分类号： A61L31/18 , A61B6/12 , A61B90/39 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2230/0013 , A61L31/082 , A61L31/124
摘要： Medical devices, such as endoprostheses, are disclosed. In some embodiments, an endoprosthesis includes a tubular body including a first material having a first mass attenuation coefficient; and a coating (24) on less than or equal to half of a (e.g., any) circumferential cross section occupied by the body. The coating includes a second material having a second mass attenuation coefficient greater than the first mass attenuation coefficient. When placed in a body, the endoprosthesis can be imaged using multiple types of methods, such as computed tomography.
摘要翻译：公开了医疗装置，例如内用假体。在一些实施例中，内假体包括管状主体，其包括具有第一质量衰减系数的第一材料; 以及小于或等于由身体占据的（例如，任何）圆周横截面的一半的涂层（24）。涂层包括具有大于第一质量衰减系数的第二质量衰减系数的第二材料。当放置在体内时，可以使用多种类型的方法（例如计算机断层扫描）来成像内置假体。

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