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31. 发明申请

WO1987002239A1 CONNECTOR 审中-公开
标题翻译：连接器
公开(公告)号：WO1987002239A1
公开(公告)日：1987-04-23
申请号：PCT/US1986001909
申请日：1986-09-15
申请人： KENDALL MCGAW LABORATORIES, INC.
发明人： KENDALL MCGAW LABORATORIES, INC. , MC PHEE, Charles, J.
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1475 , A61J1/2013 , A61J1/2058 , A61J2200/10
摘要： A connector (11) including a base (23) and first and second tubular members (25, 27) projecting in generally opposite directions from the base. Each of the tubular members has a longitudinal passage (29, 31) therein, and the passages are communicable with each other. The base can be coupled to first and second containers (13, 15) to place the first and second tubular members within the first and second containers, respectively, so that communication between the containers can be established. The connector includes a plurality of pointed projections (57, 65) extending away from the base to accommodate certain production tolerances in the containers.

32. 发明申请

WO1985004097A1 AN APPLIANCE FOR THE PREPARATION OF INJECTABLE MEDICAMENTS 审中-公开
标题翻译：用于制备注射用药的器具
公开(公告)号：WO1985004097A1
公开(公告)日：1985-09-26
申请号：PCT/DK1985000025
申请日：1985-03-13
申请人： CHRISTENSEN, John, Franklin , RÖRTH, Micael , MAGNUSSEN, Erik
IPC分类号： A61J01/00
CPC分类号： A61J1/1412 , A61J1/1487 , A61J1/20
摘要： An appliance for the dissolution of medicaments in the form of dry matters and the absorption of the dissolved medicament into a hypodermic syringe with a subsequent emptying the syringe of air. The appliance consists of a hemispherical, transparent top section (1) with a cylindrical neck (2) in which a self-sealing rubber stopper (6) is seated and which has a circular collar or flange (8) for an elastic fastening of a thin-walled, bag-like bottom section (10) provided with a bead (11) securing an airtight connection with the top section (1) and with foldings enabling a volume expansion when the air-pressure in the appliance rises due to a liquid being injected into a drug-ampoule already placed in the appliance. Instead of being provided with a self-sealing rubber stopper the neck (2) can be improved to be a multi-channel valve with a valve body (13, 23) which in different positions gives conductive connection between apertures in its neck meant for the insertion of tubings, hypodermic syringes etc., said connection being mutual between the apertures or between them and an axial bore hole in the valve body where a hypodermic needle (27) is inserted.
摘要翻译：用于以干物质的形式溶解药物并将溶解的药物吸收到皮下注射器中并随后排空空气注射器的器具。该器具由具有圆柱形颈部（2）的半球形透明顶部部分（1）组成，其中自密封橡胶塞（6）位于其中，并且具有用于弹性紧固的圆形套环或凸缘（8）薄壁的袋状底部部分（10），其设置有固定与顶部部分（1）的气密连接的凸缘（11），并且当设备中的空气压力由于液体而升高时，能够进行体积膨胀被注射到已经放置在器具中的药物安瓿中。除了设置自密封橡胶塞之外，颈部（2）可以改进为具有阀体（13,23）的多通道阀，其在不同位置在其颈部的孔之间提供导电连接，插入管，皮下注射器等，所述连接在孔之间或它们之间相互间以及插入皮下注射针（27）的阀体中的轴向孔。

33. 发明申请

WO1985003432A1 CLOSED DRUG DELIVERY SYSTEM 审中-公开
标题翻译：封闭药物输送系统
公开(公告)号：WO1985003432A1
公开(公告)日：1985-08-15
申请号：PCT/BE1985000001
申请日：1985-01-23
申请人： TRAVENOL EUROPEAN RESEARCH AND DEVELOPMENT CENTRE
发明人： TRAVENOL EUROPEAN RESEARCH AND DEVELOPMENT CENTRE , BOCQUET, Jacques, R. , GOLDHABER, Richard, P. , KERSTEN, Jean , MATHIAS, Jean-Marie , PEARSON, Stephen
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1462 , A61J1/201 , A61J1/2065
摘要： A sterile, closed drug delivery system (10) comprising a flexible container (12), a capsule (22) coupled to the flexible container(12) and a standard glass drug vial (36) positioned within the capsule (22). The flexible container (12) has a liquid diluent therein. The capsule (22) has supporting legs (32-35) which extend inwardly from the capsule (22) to support the vial (36) and also a highly flexible, pleated cap (28) which enables the drug vial (36) to be manually moved relative to the supporting legs (32-35). The capsule (22) is coupled to the flexible container (12) by means of a hollow spike (54) located within the capsule (22) and a frangible member (58) located within the flexible container (12), which frangible member (58) allows fluid passage only when it is broken. Manual pressing of the pleated cap (28) moves the drug vial downwardly onto the spike (54), piercing the stopper of the drug vial (36). Once the frangible member (58) is broken, there is sterile communication between the drug vial (36) and the liquid diluent contents of the flexible container (12).

34. 发明申请

WO1984004672A1 A PRESSURE BALANCING DEVICE FOR SEALED VESSELS 审中-公开
标题翻译：密封容器的压力平衡装置
公开(公告)号：WO1984004672A1
公开(公告)日：1984-12-06
申请号：PCT/SE1984000195
申请日：1984-05-21
申请人： GUSTAVSSON, Bengt
IPC分类号： A61J01/00
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2013 , A61J1/2072 , A61J1/2075 , A61J1/2082 , A61M5/3243
摘要： Device for ventilating and pressure balancing the interior of a sealed vessel (1) containing a substance which is to be taken out from said vessel e.g. by an injection syringe, said vessel being provided with a closure means (2) comprising a sealing member (2) through which a puncturing member, e.g. a needle can be passed for entering the interior of said vessel. The closure means (2) or a connection means (3) attachable onto said vessel is provided with ventilating means (10; 13; 14, 15) arranged to provide a communication between the interior of the vessel (1) and a closed container or alternatively the atmosphere via a filter (16).
摘要翻译：用于对包含要从所述容器取出的物质的密封容器（1）的内部进行通风和压力平衡的装置，例如，通过注射器，所述容器设置有包括密封构件（2）的封闭装置（2），穿刺构件例如穿过所述密封构件。可以通过针进入所述容器的内部。封闭装置（2）或可连接到所述容器上的连接装置（3）设置有通风装置（10; 13; 14,15），其布置成在容器（1）的内部和密封容器之间提供连通或者通过过滤器（16）的气氛。

35. 发明申请

WO1983003540A1 STERILE COUPLING 审中-公开
公开(公告)号：WO1983003540A1
公开(公告)日：1983-10-27
申请号：PCT/US1983000358
申请日：1983-03-14
申请人： BAXTER TRAVENOL LABORATORIES, INC.
发明人： BAXTER TRAVENOL LABORATORIES, INC. , PEARSON, Stephen
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/201 , A61J1/2017 , A61J1/2072 , Y10S604/905
摘要： Un raccordement stérile (124) permet l'établissement sélectif d'un passage stérile (118) entre deux réceptacles séparés (22, 80). Un raccordement en plastique de préférence moulé par injection (76) est créé autour d'au moins les parties extrêmes (78, 104) des organes d'accès (44, 90) pour chacun des réceptacles séparés (22, 80). Le raccordement permet d'obtenir un couplage stérile de manière à amener sélectivement l'organe d'accès en communication avec le passage et établir ainsi un passage stérile (118) entre les réceptacles au travers de l'organe d'accès. Des procédés de fabrication d'un couplage stérile et des procédés permettant de créer un passage stérile entre les réceptacles sont également décrits, ainsi qu'un procédé de moulage par injection à basse pression.

36. 发明申请

WO1983003351A1 POUCH-LIKE BAGS FOR CONTAINING LIQUIDS 审中-公开
标题翻译： POUCH-LIKE袋包含液体
公开(公告)号：WO1983003351A1
公开(公告)日：1983-10-13
申请号：PCT/GB1983000086
申请日：1983-03-23
申请人： METAL BOX p.l.c. , ASHLEY, Robert, John , BARDHAN, Nabendu , HARDY, Peter, Derek , JEFFS, Keith, Derek
发明人： METAL BOX p.l.c.
IPC分类号： A61J01/00
CPC分类号： A61J1/00 , B65D33/00
摘要： A pouch-like bag for containing a liquid for medical or surgical use has two walls (10, 11) formed by respective plies of flexible plastics material sealed together (at 12) around at least their top and side edges and a third, folded ply (14) of flexible plastics material of substantially smaller dimensions forming a gusset bottom and having opposed leaves (16, 17) each of which is sealed (at 18) to the adjacent wall (10, 11). The gusset ply (14) carries one or more elements (21, 22) of elastomeric material capable of making an hermetic and liquid-tight seal with a needle, e.g. an administration set needle for a hospital drip-feed system or a hypodermic or injection needle for injecting a drug into the bag contents. The gusset ply (14) is closed below the elastomeric elements (21, 22) by a seal (27) between its leaves to form a sealed compartment which can be opened, either by peeling open the seal (27) or by cutting or tearing, whereupon it forms a substantially flat bottom of the bag and presents the elements (21, 22) substantially perpendicular to the walls (10, 11) for insertion of a needle or needles without risk of accidental penetration of the walls.
摘要翻译：用于容纳用于医疗或外科用途的液体的袋状袋具有两个壁（10,11），所述两个壁（10,11）由相应的柔性塑料材料层形成，所述柔性塑料材料层至少在其顶部和侧部边缘处密封在一起（在12处）和第三个折叠的层（14），其具有基本较小尺寸的柔性塑料材料，形成角撑板底部并且具有相对的叶片（16,17），每个叶片彼此密封（在18°）到邻近的壁（10,11）。角撑板层（14）承载弹性体材料的一个或多个元件（21,22），其能够用针进行密封和液密密封。用于医院滴注系统的管理针管或用于将药物注射到袋内容物中的皮下注射针或注射针。角撑板层（14）通过其叶片之间的密封件（27）封闭在弹性体元件（21,22）下方，以形成可以通过剥离打开密封件（27）或通过切割或撕裂而打开的密封隔室因此，它形成袋的基本上平坦的底部并且呈现基本上垂直于壁（10,11）的元件（21,22），用于插入针或针，而不会有意图渗透壁的风险。

37. 发明申请

WO1982001992A1 PILL BOX 审中-公开
标题翻译：药盒
公开(公告)号：WO1982001992A1
公开(公告)日：1982-06-24
申请号：PCT/AU1981000175
申请日：1981-12-01
申请人： WRENNALL RICHARD K
IPC分类号： A61J01/00
CPC分类号： B65D83/0454 , A61J7/04 , B65D2583/0409 , Y02W30/807
摘要： A re-usable, solid-dosage form, pharmaceutical dispenser in the form of a flat, circular box divided into dosage time interval compartments by annular walls (18) (19) (20) (21) and radial walls (11) (12) (13) (14) (15) (16) (17) and covered by two removable, superposed contra-rotating lids; a lower lid (24) has a single radial sector, major dosage, time interval access slot (25) extending radially completely across the compartments, the upper lid (27) has a series of radially staggered, minor dosage time interval access slots (29) (30) (31) (32) which successively uncover annular compartments in the same radial sector. Both lids and the stepped outer peripheral container wall (34) have co-operating click stop means (35) (36) (37) (38) for progressively setting the lids, in major and minor dosage time interval positions.
摘要翻译：一种可重复使用的固体剂型，药物分配器，其形式为平坦的圆形盒，分为环形壁（18）（19）（20）（21）和径向壁（11）（12））（13）（14）（15）（16）（17），并被两个可拆卸，重叠的反转盖子覆盖; 下盖（24）具有单个径向扇区，主要剂量，时间间隔进入狭槽（25），其径向延伸穿过隔室，上盖（27）具有一系列径向交错的次要剂量时间间隔进入狭槽（29））（30）（31）（32），其相继地在相同的径向扇区中露出环形隔室。两个盖和台阶外周边容器壁（34）具有合作的止回装置（35）（36）（37）（38），用于在主要和次要剂量时间间隔位置逐渐设置盖子。

38. 发明申请

WO1981003275A1 ARTICLE FOR STORAGE AND TRANSPORT OF BIOGENIC FLUIDS 审中-公开
标题翻译：生物流体储存和运输物品
公开(公告)号：WO1981003275A1
公开(公告)日：1981-11-26
申请号：PCT/US1981000609
申请日：1981-05-04
申请人： PENNWALT CORP
发明人： PENNWALT CORP , THANAWALLA C , SOULEN J
IPC分类号： A61J01/00
CPC分类号： A61L2/206 , A61J1/1468 , Y10S128/24
摘要： An article for storage and transport of biogenic fluids such as blood, blood fractions, intravenous feeding solutions and liquid phase-delivered drugs is formed of an additive-free uncharge thermoplastic polymer of vinylidene fluoride copolymerized with a monomer.

39. 发明申请

WO1998018425A1 A SYSTEM, METHOD AND DEVICE FOR CONTROLLABLY RELEASING A PRODUCT 审中-公开
标题翻译：一种用于控制产品释放的系统，方法和装置
公开(公告)号：WO1998018425A1
公开(公告)日：1998-05-07
申请号：PCT/US1997019423
申请日：1997-10-28
申请人： BAXTER INTERNATIONAL INC.
发明人： BAXTER INTERNATIONAL INC. , QIN, Chuan , DING, Yuanpang, Samuel , CHEN, Chi , RIPLEY, Jerry
IPC分类号： A61J01/00
CPC分类号： A61J1/20 , B65D81/3222 , Y10T137/1963 , Y10T137/2012
摘要： A device, a system and a method are provided for controllably releasing a product (26) into a container (10) in which the product (26) is mixed with another product contained within an interior (14) of the container (10). The device (12) releases the product (26) due to variations in temperature or pressure that the system experiences during an autoclaving or sterilization procedure, for example. Materials and shapes of the members (20, 20a, 20b, 22) of the device (12) are selected such that the members (20, 20a, 20b, 22) react or otherwise move within the device in a predetermined manner in response to changes in temperature or pressure. As a result, products (26) within the device (12) may be maintained separately from products within the interior (14) of the container (10) in which the device (12) is held. Prior to administration of a solution within the container (10), the product (26) within the device (12) may be mixed with the solution or other product in the container (10) in a controllable fashion.
摘要翻译：提供了一种装置，系统和方法，用于将产品（26）可控地释放到容器（10）中，在容器（10）中，产品（26）与容纳在容器（10）的内部（14）内的另一种产品混合。例如，由于系统在高压灭菌或灭菌过程中经历的温度或压力的变化，装置（12）释放产品（26）。选择装置（12）的构件（20,20a，20b，22）的材料和形状，使得构件（20,20a，20b，22）响应于预定方式反应或以其它方式在装置内移动温度或压力变化。因此，装置（12）内的产品（26）可以与装置（12）所在的容器（10）的内部（14）内的产品分开地保持。在容器（10）内施用溶液之前，装置（12）内的产品（26）可以以可控的方式与容器（10）中的溶液或其它产品混合。

40. 发明申请

WO1997017934A1 AQUEOUS ACYCLOVIR FORMULATION AND METHOD FOR STORING SAME 审中-公开
标题翻译：水性ACYCLOVIR配方及其储存方法
公开(公告)号：WO1997017934A1
公开(公告)日：1997-05-22
申请号：PCT/US1996017615
申请日：1996-11-04
申请人： ABBOTT LABORATORIES
发明人： ABBOTT LABORATORIES , RHODES, Lawrence, J. , KLANDRUD, Kathee, E.
IPC分类号： A61J01/00
CPC分类号： A61J1/00
摘要： A method for storing a solution containing acyclovir and a pharmaceutical product containing an acyclovir solution. The method includes the steps of providing a predetermined volume of an acyclovir solution suitable for parenteral administration to a patient and providing a container constructed to contain the predetermined volume. The container is constructed from a material containing polymethylpentene and defines an opening. The acyclovir solution is placed into the container. The method further includes the step of providing a stopper configured to seal fluidly the opening defined by the container. The container is then sealed using the stopper. The pharmaceutical product includes an acyclovir solution contained by a container constructed from a material containing polymethylpentene. The container defines an opening therethrough. The product further includes a stopper coated with a fluorinated resin. The stopper fluidly seals the opening defined by the container.
摘要翻译：一种用于储存含有阿昔洛韦和含有阿昔洛韦溶液的药物的溶液的方法。该方法包括以下步骤：提供适合于向患者肠胃外给药的预定体积的阿昔洛韦溶液，并提供构造成容纳预定体积的容器。容器由含有聚甲基戊烯的材料构成并限定开口。将阿昔洛韦溶液置于容器中。该方法进一步包括提供一个止动器的步骤，该止动器构造成将流体密封由容器限定的开口。然后使用塞子密封容器。药物产品包括由含有聚甲基戊烯的材料构成的容器所含的阿昔洛韦溶液。容器限定穿过其中的开口。该产品还包括涂覆有氟化树脂的塞子。止动器流体地密封由容器限定的开口。

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