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31. 发明申请

WO2013022853A1 CATHETER BALLOON METHODS AND APPARATUS EMPLOYING SENSING ELEMENTS 审中-公开
标题翻译：导管气球方法和装置采用感应元件
公开(公告)号：WO2013022853A1
公开(公告)日：2013-02-14
申请号：PCT/US2012/049787
申请日：2012-08-06
申请人： MC10, INC. , D'ANGELO, Robert , DE GRAFF, Bassel , DOWLING, Kevin , GHAFFARI, Roozbeh , KLINKER, Lauren , LEE, Stephen P. , LIU, Cliff , HSU, Yung-Yu
发明人： D'ANGELO, Robert , DE GRAFF, Bassel , DOWLING, Kevin , GHAFFARI, Roozbeh , KLINKER, Lauren , LEE, Stephen P. , LIU, Cliff , HSU, Yung-Yu
IPC分类号： A61M29/00
CPC分类号： A61B5/0538 , A61B5/02158 , A61B5/026 , A61B5/036 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B5/742 , A61B6/12 , A61B18/02 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B18/24 , A61B2017/00526 , A61B2018/0016 , A61B2018/0022 , A61B2018/00267 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00773 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/0212 , A61B2090/065 , A61B2562/046 , A61B2562/125 , A61B2562/222 , A61M25/1002 , A61N7/02 , A61N7/022 , A61N2007/0078 , Y10T29/49002 , Y10T156/1089
摘要： An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of sensing elements disposed on the flexible substrate. The plurality of sensing elements are disposed about the inflatable body such that the sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state
摘要翻译：提供了用于医疗诊断和/或治疗的装置。该装置包括形成可膨胀体的柔性基底和设置在柔性基底上的多个感测元件。多个感测元件围绕可充气体设置，使得感测元件设置在充气体的最小曲率的区域处于放气状态

32. 发明申请

WO2012136786A1 TRANSOESOPHAGEAL DEVICE USING HIGH INTENSITY FOCUSED ULTRASOUNDS FOR CARDIAC THERMAL ABLATION 审中-公开
标题翻译：使用高强度聚焦超声波治疗心脏热消融的血管内装置
公开(公告)号：WO2012136786A1
公开(公告)日：2012-10-11
申请号：PCT/EP2012/056320
申请日：2012-04-05
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , CHAPELON, Jean-Yves , CONSTANCIEL, Elodie , LAFON, Cyril
发明人： CHAPELON, Jean-Yves , CONSTANCIEL, Elodie , LAFON, Cyril
IPC分类号： A61N7/02 , A61N7/00 , A61B18/00 , A61B19/00
CPC分类号： A61B5/4836 , A61B8/48 , A61B17/320068 , A61B2018/00023 , A61B2090/3784 , A61N7/022 , A61N2007/0078 , A61N2007/0082 , A61N2007/0091 , A61N2007/0095
摘要： The present invention relates to a probe comprising: - a piezoelectric therapy transducer having an acoustic axis BB', and - an imaging transducer having an imaging plane, said therapy transducer and imaging transducer being mounted in a head itself connected to a guide means wherein: - the therapy transducer has a spherical concave front face for emitting ultrasonic waves focused on a focal point, a rear surface, a length d 1 , a width t and is a ID annular phased array transducer and; - the imaging transducer is a multiplane transducer having a rotation axis corresponding to the acoustic axis of the therapy transducer whereby the focal point of the therapy transducer is comprised in the imaging plane of the imaging transducer, said imaging transducer being fixed to the therapy transducer.
摘要翻译：本发明涉及一种探针，包括： - 具有声轴BB'的压电治疗换能器，和 - 具有成像平面的成像换能器，所述治疗换能器和成像换能器安装在头部中，其自身连接到引导装置，其中： - 治疗传感器具有球面凹面，用于发射聚焦在焦点，后表面，长度d1，宽度t上的超声波，并且是ID环形相控阵转换器; - 所述成像换能器是具有对应于所述治疗换能器的声轴的旋转轴的多平面换能器，由此所述治疗换能器的焦点包含在所述成像换能器的成像平面中，所述成像换能器固定到所述治疗换能器。

33. 发明申请

WO2012131383A1 INTERVERTEBRAL DISC TREATMENT APPARATUS 审中-公开
标题翻译：椎间盘治疗装置
公开(公告)号：WO2012131383A1
公开(公告)日：2012-10-04
申请号：PCT/GB2012/050714
申请日：2012-03-30
申请人： ISIS INNOVATION LIMITED , MOLINARI, Michael , SIVAN, Sarit , GIBBONS, Dare-Sean , ARORA, Manish , URBAN, Jill , COUSSIOS, Constantin
发明人： MOLINARI, Michael , SIVAN, Sarit , GIBBONS, Dare-Sean , ARORA, Manish , URBAN, Jill , COUSSIOS, Constantin
IPC分类号： A61B17/16 , A61B17/32
CPC分类号： A61B17/320068 , A61B17/22004 , A61B17/3472 , A61B2017/00261 , A61B2017/22008 , A61B2017/564 , A61B2018/00339 , A61B2090/378 , A61B2217/005 , A61N7/02 , A61N2007/0078
摘要： A method of at least partially removing the nucleus pulposus of an intervertebral disc comprising the nucleus and an annulus surrounding the nucleus is described. The method comprises the steps of : insonating the nucleus with ultrasound thereby to cause at least partial fragmentation of the nucleus; and extracting at least part of the fragmented nucleus. A system for performing the method is also described.
摘要翻译：描述了至少部分地去除包括核的椎间盘的髓核和围绕细胞核的环的方法。该方法包括以下步骤：用超声引发细胞核，从而使细胞核至少部分分裂; 并提取碎片核的至少一部分。还描述了用于执行该方法的系统。

34. 发明申请

WO2012120495A2 TISSUE TREATMENT AND MONITORING BY APPLICATION OF ENERGY 审中-公开
标题翻译：通过应用能源组织治疗和监测
公开(公告)号：WO2012120495A2
公开(公告)日：2012-09-13
申请号：PCT/IL2012/000100
申请日：2012-03-04
申请人： RAINBOW MEDICAL LTD. , GROSS, Yossi , KARDOSH, Michael , MEIRY, Gideon , TSOREF, Liat , KUSHKULEY, Leonid , ASSAF, Yaron
发明人： GROSS, Yossi , KARDOSH, Michael , MEIRY, Gideon , TSOREF, Liat , KUSHKULEY, Leonid , ASSAF, Yaron
IPC分类号： A61N7/00
CPC分类号： A61N7/022 , A61B5/4836 , A61B8/12 , A61B8/445 , A61B8/546 , A61B2017/22069 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61N2007/0043 , A61N2007/0078 , A61N2007/0086 , A61N2007/0091
摘要： Apparatus is provided, which includes at least one ultrasound transducer. The ultrasound transducer is configured to be positioned within a lumen of a subject and to ablate tissue surrounding a wall of the lumen without ablating the wall of the lumen, by focusing ultrasound energy on a focal zone that is outside of the wall of the lumen. A transluminal delivery tool is configured to position the ultrasound transducer in the lumen, and a control unit is configured to drive the ultrasound transducer. Other embodiments are also described.
摘要翻译：提供了包括至少一个超声换能器的装置。超声换能器被配置为定位在受试者的内腔内，并且通过将超声能量聚焦在位于管腔壁外部的聚焦区域上而消融内腔壁周围的组织，而不会消融内腔壁。经腔递送工具被配置为将超声换能器定位在内腔中，并且控制单元被配置为驱动超声换能器。还描述了其它实施例。

35. 发明申请

WO2012112165A1 APPARATUS FOR EFFECTING RENAL DENERVATION USING ULTRASOUND 审中-公开
标题翻译：用超声波治疗肾功能衰竭的装置
公开(公告)号：WO2012112165A1
公开(公告)日：2012-08-23
申请号：PCT/US2011/025543
申请日：2011-02-18
申请人： RECOR MEDICAL, INC. , IYER, Mano , MERINO, Jaime E. , MAYNARD JR., Kenneth J.
发明人： IYER, Mano , MERINO, Jaime E. , MAYNARD JR., Kenneth J.
IPC分类号： A61N7/02
CPC分类号： A61N7/022 , A61N2007/003 , A61N2007/0069 , A61N2007/0078
摘要： An ultrasound apparatus is provided for non-continuous circumferential treatment of a vessel, such to provide denervation of a renal blood vessel. The apparatus may be positioned within a vessel to deliver broad unfocused or focused ultrasonic energy at first and second lengthwise and angular positions to create a less-than-full circumferential treatment zone at each of the first and second positions. Superimposition of treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion.
摘要翻译：提供超声装置用于不连续地周边处理血管，从而提供肾血管的去神经支配。该装置可以位于容器内以在第一和第二纵向和角度位置处输送宽泛的未聚焦或聚焦的超声波能量，以在第一和第二位置的每一个处产生小于全部的圆周处理区域。处理区域的叠加限定了不连续的周向处理区域，而不形成连续的周向损伤。

36. 发明申请

WO2012052927A1 AN ULTRASOUND TRANSCEIVER AND COOLING THEREOF 审中-公开
标题翻译：超声波收发器和冷却器
公开(公告)号：WO2012052927A1
公开(公告)日：2012-04-26
申请号：PCT/IB2011/054641
申请日：2011-10-18
申请人： CARDIOSONIC LTD. , SVERDLIK, Ariel , SHABTAY, Or
发明人： SVERDLIK, Ariel , SHABTAY, Or
IPC分类号： A61N7/00
CPC分类号： A61B17/320068 , A61B17/2202 , A61B2017/00106 , A61B2017/22008 , A61B2017/22051 , A61B2017/22081 , A61B2090/378 , A61M37/0092 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： An ultrasonic transceiver device for producing ultrasonic beams comprises a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, the device configured to produce an unfocused, or alternatively a focused, power beam for thermal tissue damage, the power beam being produced by vibration over the body of the transceiver and emanating from the extent of the surface, whereby the extensive surface becomes subject to convective cooling when immersed in a fluid by a chimney effect set up by said unfocused beam.
摘要翻译：一种用于生产超声波束的超声波收发器装置包括可在超声波频率下振动的主体和用于束发射的广泛表面，该装置被配置为产生未聚焦或者聚焦的用于热组织损伤的功率束，该功率束由振动产生在收发器的主体上并从表面的范围发出，由此当通过由未聚焦的光束设置的烟囱效应将广泛的表面浸入流体时，广泛的表面变得受到对流冷却。

37. 发明申请

WO2011163570A3 HYDROGEL ULTRASOUND COUPLING DEVICE 审中-公开
标题翻译： HYDROGEL超声波耦合器件
公开(公告)号：WO2011163570A3
公开(公告)日：2012-04-19
申请号：PCT/US2011041787
申请日：2011-06-24
申请人： ZETROZ LLC , LEWIS JR GEORGE K , GUARINO JOANNE L , GUFFEY BRYANT
发明人： LEWIS JR GEORGE K , GUARINO JOANNE L , GUFFEY BRYANT
IPC分类号： A61B8/00 , A61N7/00
CPC分类号： A61N7/00 , A61B8/4236 , A61B8/4281 , A61N2007/0034 , A61N2007/0056 , A61N2007/006 , A61N2007/0078
摘要： The present invention relates to an ultrasound coupling device that includes a gel component and a coupling compartment. The present invention also relates to various kits and methods for using the ultrasound coupling device with low-intensity ultrasound transducers and therapy. The present invention also relates to methods of making the ultrasound coupling device of the present invention. The present invention further relates to an array that includes a plurality of ultrasound coupling devices of the present invention, and methods of using the array.
摘要翻译：本发明涉及一种超声耦合装置，其包括凝胶组件和耦合室。本发明还涉及使用具有低强度超声换能器和治疗的超声耦合装置的各种试剂盒和方法。本发明还涉及制造本发明的超声波耦合器件的方法。本发明还涉及包括本发明的多个超声耦合装置的阵列，以及使用阵列的方法。

38. 发明申请

WO2012042494A1 MONITORING AND CONTROL OF MICROBUBBLE CAVITATION IN THERAPEUTIC ULTRASOUND 审中-公开
标题翻译：监测和控制治疗超声中的微生物腔
公开(公告)号：WO2012042494A1
公开(公告)日：2012-04-05
申请号：PCT/IB2011/054287
申请日：2011-09-29
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VIGNON, Francois, Guy, Gerard, Marie , SHI, William, Tao , POWERS, Jeffry, Earl
发明人： VIGNON, Francois, Guy, Gerard, Marie , SHI, William, Tao , POWERS, Jeffry, Earl
IPC分类号： A61B8/06 , A61N7/00 , A61B8/08
CPC分类号： A61B8/481 , A61B8/06 , A61B8/0808 , A61B8/13 , A61B8/461 , A61B8/5238 , A61B17/225 , A61B17/2256 , A61B34/25 , A61B2017/00119 , A61B2017/22008 , A61B2090/378 , A61N7/00 , A61N2007/0039 , A61N2007/0078 , G01S7/52038 , G01S7/52071 , G01S15/899
摘要： An ultrasonic diagnostic imaging system performs microbubble-mediated therapy such as sonothrombolysis or encapsulated drug delivery. The site of the therapeutic procedure is imaged by harmonic imaging. The type and amount of cavitation present in the image field is detected by performing cavitation imaging, which detects echo characteristics indicative of different types of cavitation at locations in the image field. A colorized image overlay is produced, with one color indicating locations of stable cavitation and another indicating locations of inertial cavitation. The colorized image is overlaid or combined with a B mode image to indicate the cavitation locations and its type to a user. The user can adjust the transmit power of the ultrasound system until the desired amount and type of cavitation is produced at the therapy site.
摘要翻译：超声诊断成像系统执行微泡介导的治疗，例如溶栓或包封的药物递送。治疗过程的部位通过谐波成像进行成像。通过执行气蚀成像来检测存在于图像场中的气蚀的类型和量，其检测指示图像场中位置处的不同类型的空化的回波特性。产生着色图像覆盖层，其中一种颜色指示稳定气穴的位置，另一种指示惯性空化的位置。彩色图像被叠加或与B模式图像组合以指示空穴位置及其对用户的类型。用户可以调整超声系统的发射功率，直到在治疗部位产生所需的气蚀数量和类型。

39. 发明申请

WO2012042423A1 MONITORING AND CONTROL OF MICROBUBBLE CAVITATION IN THERAPEUTIC ULTRASOUND 审中-公开
标题翻译：监测和控制在治疗超声中的微生物腔
公开(公告)号：WO2012042423A1
公开(公告)日：2012-04-05
申请号：PCT/IB2011/054049
申请日：2011-09-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VIGNON, Francois Guy Gerard Marie , SHI, William Tao , POWERS, Jeffry Earl
发明人： VIGNON, Francois Guy Gerard Marie , SHI, William Tao , POWERS, Jeffry Earl
IPC分类号： A61B8/06 , A61N7/00 , A61B8/08
CPC分类号： A61B8/481 , A61B8/06 , A61B8/0808 , A61B8/13 , A61B8/461 , A61B8/5238 , A61B17/225 , A61B17/2256 , A61B34/25 , A61B2017/00119 , A61B2017/22008 , A61B2090/378 , A61N7/00 , A61N2007/0039 , A61N2007/0078 , G01S7/52038 , G01S7/52071 , G01S15/899
摘要： An ultrasonic diagnostic imaging system performs microbubble-mediated therapy such as sonothrombolysis or encapsulated drug delivery. The site of the therapeutic procedure is imaged by harmonic imaging. The type and amount of cavitation present in the image field is detected by performing cavitation imaging, which detects echo characteristics indicative of different types of cavitation at locations in the image field. A colorized image overlay is produced, with one color indicating locations of stable cavitation and another indicating locations of inertial cavitation. The colorized image is overlaid or combined with a B mode image to indicate the cavitation locations and its type to a user. A user alert is produced when the system detects an undesired level of inertial cavitation.
摘要翻译：超声诊断成像系统执行微泡介导的治疗，例如溶栓或包封的药物递送。治疗过程的部位通过谐波成像进行成像。通过执行气蚀成像来检测存在于图像场中的气蚀的类型和量，其检测指示图像场中位置处的不同类型的空化的回波特性。产生着色图像覆盖层，其中一种颜色指示稳定气蚀的位置，另一种指示惯性空化的位置。着色图像被覆盖或与B模式图像组合以指示空穴位置及其对用户的类型。当系统检测到不期望的惯性空化水平时，产生用户警报。

40. 发明申请

WO2011148940A1 超音波便秘改善器审中-公开
标题翻译：超声波消除装置
公开(公告)号：WO2011148940A1
公开(公告)日：2011-12-01
申请号：PCT/JP2011/061867
申请日：2011-05-24
申请人：インターチェンジジャパン株式会社 , 筒井 ▲将▼仁
发明人：筒井　▲将▼仁
IPC分类号： A61H39/00 , A61H23/02 , A61N1/32
CPC分类号： A61H23/0245 , A61H2201/5023 , A61H2201/5043 , A61H2205/081 , A61N7/00 , A61N2007/0026 , A61N2007/0078
摘要：　背中から腰椎とその付近に刺激を与えて便秘改善可能な治療器を実現する。超音波信号発振回路と、背中から、第３腰椎と第４腰椎間、又は第４腰椎と第５腰椎間、又は第３腰椎～第５腰椎のいずれか一又は二以上に宛がうことのできるヘッドを設け、ヘッドは背中から前記腰椎又は腰椎間に伝達できる超音波を発生する圧電振動子を備え、ヘッドは前記第３腰椎と第４腰椎間、又は第４腰椎と第５腰椎間、又は第３腰椎～第５腰椎のいずれか一又は二以上に宛がうことのできるサイズであり、便秘に関するつぼや神経を刺激できる出力強度と前記周波数の超音波振動を出力できるようにした。
摘要翻译：公开了一种治疗装置，其能够通过将刺激从背部施加到腰椎及其附近而缓解便秘。提供超声波信号振荡电路和磁头。头部能够从背部施加到第三腰椎和第四腰椎之间的间隔中的一个或两个或更多个间隔，或第四腰椎与第五腰椎之间的间隔，或第三腰部椎骨到第五个腰椎。头部设置有压电振荡器，其产生能够从背部传递到腰椎或腰椎之间的超声波。头部的尺寸能够应用于第三腰椎和第四腰椎之间的间隔中的一个或两个或更多个间隔，或第四腰椎与第五腰椎之间的间隔，或第三腰部椎骨到第五个腰椎。该头能够输出能够刺激便秘时所引起的压力点或神经的输出强度，并且能够输出所述频率的超声波振动。

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