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31. 发明申请

WO2016207699A1 ENABLING HIGHER-ORDER MODULATION IN A CELLULAR NETWORK 审中-公开
标题翻译：在细胞网络中实现高阶调制
公开(公告)号：WO2016207699A1
公开(公告)日：2016-12-29
申请号：PCT/IB2015/054803
申请日：2015-06-25
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)
发明人： BONTU, Chandra Sekhar , CHEN, Xixian , LUO, Kevin , REN, Hong , XU, Hua
IPC分类号： H04L1/00
CPC分类号： H04L5/006 , H04L1/0019 , H04L1/003 , H04W24/08 , H04W72/0413 , H04W72/042
摘要： A method for using a high order modulation (HoM) mode for communications with a wireless device in a wireless communication network is provided. The method includes receiving downlink channel quality indicator (CQI) information from an uplink transmission of the wireless device and determining a downlink channel quality estimate from the CQI information. When a measurement of the downlink channel quality estimate satisfies the predetermined criteria for a first predetermined number of consecutive uplink transmissions from the wireless device, a downlink transmission mode of the wireless device is switched from a first modulation mode to the HoM mode.
摘要翻译：提供了一种在无线通信网络中使用高阶调制（HoM）模式与无线设备进行通信的方法。该方法包括从无线设备的上行链路传输接收下行链路信道质量指示符（CQI）信息，并根据CQI信息确定下行链路信道质量估计。当下行链路信道质量估计的测量满足来自无线设备的第一预定数量的连续上行链路传输的预定标准时，无线设备的下行链路传输模式从第一调制模式切换到HoM模式。

32. 发明申请

WO2016124984A1 DYNAMIC CELL BREATHING FOR POWER SAVING 审中-公开
标题翻译：用于节电的动态细胞呼吸
公开(公告)号：WO2016124984A1
公开(公告)日：2016-08-11
申请号：PCT/IB2015/050922
申请日：2015-02-06
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)
发明人： REN, Hong , LUO, Kevin
IPC分类号： H04W52/34 , H04W52/36 , H04W52/54 , H04W52/14
CPC分类号： H04W52/343 , H04W52/143 , H04W52/226 , H04W52/362 , H04W52/367 , H04W52/54
摘要： Systems and methods for dynamic cell breathing for power saving are disclosed. In some embodiments, a method of operation of a radio access node includes determining a target transmit power level from multiple predetermined transmit power levels for the radio access node. The method also includes determining that the current transmit power level should be adjusted to reach the target transmit power level and, in response, adjusting a transmit power level of the radio access node from the current transmit power level to the target transmit power level via multiple transmit power level adjustments. Adjusting the power level of the radio access node via more than one transmit power level adjustment makes it possible to avoid some of the issues with the sleep mode proposal, according to some embodiments.
摘要翻译：公开了用于省电的动态细胞呼吸的系统和方法。在一些实施例中，无线电接入节点的操作方法包括从无线电接入节点的多个预定发射功率电平确定目标发射功率电平。该方法还包括确定应当调整当前发射功率电平以达到目标发射功率电平，并且作为响应，通过多个调整将无线电接入节点的发射功率电平从当前发射功率电平调整到目标发射功率电平传输功率电平调整。根据一些实施例，通过多于一个发射功率电平调整来调整无线电接入节点的功率电平使得可以避免睡眠模式建议的一些问题。

33. 发明申请

WO2012075318A3 FN1 AND ALK GENE TRANSLOCATIONS IN CANCER AND ALK KINASE EXPRESSION IN OVARIAN CANCER 审中-公开
公开(公告)号：WO2012075318A3
公开(公告)日：2012-06-07
申请号：PCT/US2011/062935
申请日：2011-12-01
申请人： CELL SIGNALING TECHNOLOGY, INC. , REN, Hong , TAN, Zhi-Ping
发明人： REN, Hong , TAN, Zhi-Ping
IPC分类号： C12Q1/68
摘要： The invention provides the identification of the presence of polypeptides with ALK kinase activity in human cancer, such as ovarian cancer. In some embodiments, the polypeptide with ALK kinase activity is the result of a fusion between an ALK-encoding polynucleotide and an FNI-encoding polynucleotide. Six different fusion polypeptides are described, three that include the transmembrane and kinase domains ofALK fused to the extracellular domain of the FNI protein, and three that include the kinase domain (but not the transmembrane domain) ofALK fused to the extracellular domain of the FNI protein.

34. 发明申请

WO2004029585A1 METHODS AND APPARATUS FOR MANIPULATING DROPLETS BY ELECTROWETTING-BASED TECHNIQUES 审中-公开
标题翻译：通过电镀技术控制滴定液的方法和装置
公开(公告)号：WO2004029585A1
公开(公告)日：2004-04-08
申请号：PCT/US2003/012753
申请日：2003-04-24
申请人： DUKE UNIVERSITY , PAMULA, Vamsee, K. , POLLACK, Michael, G. , PAIK, Philip, Y. , REN, Hong , FAIR, Richard, B.
发明人： PAMULA, Vamsee, K. , POLLACK, Michael, G. , PAIK, Philip, Y. , REN, Hong , FAIR, Richard, B.
IPC分类号： G01N1/00
CPC分类号： B01F13/0071 , B01F13/0076 , B01F13/0084 , B01J2219/00479 , B01J2219/00653 , B01L3/502792 , B01L2300/089 , B01L2300/165 , B01L2400/0415 , B01L2400/0427 , C40B60/14 , G01N15/14 , G01N2035/1046 , G02B26/005 , Y10T436/11 , Y10T436/113332 , Y10T436/117497 , Y10T436/118339 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： In a method for sampling a continuous liquid flow, the liquid flow is supplied to a surface along an input flow path. The liquid flow is sampled by forming a sample droplet from a portion of the liquid flow. The sample droplet is moved along an analysis flow path to a processing area of the surface, where the sample droplet is processed. Discrete sample droplets are formed and moved using an electrowetting technique. A binary mixing apparatus and method are also provided. The apparatus comprises an array of electrodes, an electronic controller communicating with the electrodes, a sample droplet supply area communicating with the array, and an additive droplet supply area communicating with the array. The electronic controller alternately energizes and de-energizes selected electrodes to carry out droplet-to-droplet binary mixing operations to obtain one or more droplets having a target mixing ratio.
摘要翻译：在对连续液体流进行取样的方法中，液体流被输送到沿输入流路的表面。通过从液体流的一部分形成样品液滴来取样液体流。样品液滴沿着分析流动路径移动到表面的处理区域，在该处理区域处理样品液滴。使用电润湿技术形成和移动离散样品液滴。还提供了二元混合装置和方法。该装置包括电极阵列，与电极连通的电子控制器，与该阵列连通的样品液滴供应区域以及与该阵列连通的附加液滴供应区域。电子控制器交替地激励和去激活所选择的电极以进行液滴到液滴的二进制混合操作以获得具有目标混合比的一个或多个液滴。

35. 发明申请

WO2013118028A1 ALLOCATING CONTROL CHANNEL ELEMENTS TO DOWNLINK CONTROL CHANNELS 审中-公开
标题翻译：分配控制通道元素到下行控制通道
公开(公告)号：WO2013118028A1
公开(公告)日：2013-08-15
申请号：PCT/IB2013/050765
申请日：2013-01-29
申请人： TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) , REN, Hong
发明人： REN, Hong
IPC分类号： H04L5/00
CPC分类号： H04L5/0053 , H04L27/2601
摘要： A method and apparatus is provided for allocating shared control channel resources. The control channel elements (CCEs) are allocated in units referred to as CCE sets. Each CCE set includes one or more control channel elements. Early commitment of control channel elements in a CCE set to a specific scheduling entity is avoided in situations where two or more candidate sets are available for the scheduling entity. In this case, the CCEs belonging to the candidate sets are designated as an alternate resource for a first scheduling entity. A CCE designated as an alternate may be allocated to another scheduling entity as long as such allocation does not block the first scheduling entity.
摘要翻译：提供了一种用于分配共享控制信道资源的方法和装置。控制信道单元（CCE）以被称为CCE组的单元分配。每个CCE集合包括一个或多个控制信道元素。在两个或多个候选集合可用于调度实体的情况下，避免在设置到特定调度实体的CCE中的控制信道单元的早期承诺。在这种情况下，属于候选集的CCE被指定为第一调度实体的备用资源。只要这种分配不阻止第一调度实体，指定为替换的CCE可以被分配给另一个调度实体。

36. 发明申请

WO2006079210A1 METHOD AND SYSTEM FOR DETERMINING A PAGING ZONE IN A WIRELESS NETWORK 审中-公开
标题翻译：用于确定无线网络中的分段区的方法和系统
公开(公告)号：WO2006079210A1
公开(公告)日：2006-08-03
申请号：PCT/CA2006/000106
申请日：2006-01-27
申请人： NORTEL NETWORKS LIMITED , REN, Hong , CAO, Carl , SCHMIDT, Alfred
发明人： REN, Hong , CAO, Carl , SCHMIDT, Alfred
IPC分类号： H04Q7/08
CPC分类号： H04W68/00 , H04W68/08
摘要： A method of paging a mobile terminal in a radio access network wherein the last known location of a mobile terminal is stored. A location message (also called a Route Update message) is sent from a terminal and received at a sector in the network, identifying the location of the terminal. The network determines a paging zone for that terminal based on configuration information for that sector. The configuration information for each sector typically includes a Route Update radius, and then one or both of a paging zone radius offset, and statically configured sectors. When the terminal needs to be paged, the network then broadcasts a page to the terminal in each sector in the paging zone. Such a system adjusts the paging zone to include sectors which the terminal has a reasonable likelihood of moving to before the network learns that the terminal has moved out of the previously established paging zone. Aspects of the invention provide two complementary methods of adjusting the paging zone: adjusting using a paging zone offset, and adjusting based on a sector list. The paging zone offset adjusts the radius of the paging zone, thereby maintaining a generally circular shape. The sector list adjusts the generally circular paging zone by adding or deleting any sector in any direction, thereby allowing any arbitrary shape to be used for the paging zone. The adjustments to the paging zone achieved by these methods account for such factors as RF coverage, geographic features, congestion, population density and expected rate of movement of terminals between sectors.
摘要翻译：一种在无线电接入网络中寻呼移动终端的方法，其中存储了移动终端的最后已知位置。从终端发送位置消息（也称为路由更新消息），并在网络中的扇区处接收，以识别终端的位置。该网络基于该扇区的配置信息确定该终端的寻呼区域。每个扇区的配置信息通常包括路由更新半径，然后包括寻呼区半径偏移和静态配置扇区中的一个或两个。当终端需要被寻呼时，网络然后在寻呼区域的每个扇区中向终端广播一个页面。这样的系统调整寻呼区域以包括终端在网络学习终端已经移出先前建立的寻呼区域之前具有合适的可能性的扇区。本发明的各方面提供了两种调整寻呼区域的补充方法：使用寻呼区域偏移进行调整，以及基于扇区列表进行调整。寻呼区域偏移调整寻呼区域的半径，从而保持大致圆形的形状。扇区列表通过在任何方向上添加或删除任何扇区来调整通常循环的寻呼区域，从而允许任何形状用于寻呼区域。通过这些方法实现的寻呼区域的调整涉及射频覆盖，地理特征，拥塞，人口密度和部门之间终端的预期移动速度等因素。

37. 发明申请

WO2019209607A1 NOVEL PROCESS FOR SYNTHESIS OF A PHENOXY DIAMINOPYRIMIDINE COMPOUND 审中-公开
公开(公告)号：WO2019209607A1
公开(公告)日：2019-10-31
申请号：PCT/US2019/028014
申请日：2019-04-18
申请人： MERCK SHARP & DOHME CORP. , MSD WERTHENSTEIN BIOPHARMA GMBH , MALONEY, Kevin, M. , BASU, Kallol , CHUNG, John, Y.L. , DESMOND, Richard , DI MASO, Michael James , HUMPHREY, Guy, R. , LEE, Alfred, Y. , LEHNHERR, Dan , PENG, Feng , REN, Hong , WEISEL, Mark , ZHANG, Siwei , LARPENT, Patrick
发明人： MALONEY, Kevin, M. , BASU, Kallol , CHUNG, John, Y.L. , DESMOND, Richard , DI MASO, Michael James , HUMPHREY, Guy, R. , LEE, Alfred, Y. , LEHNHERR, Dan , PENG, Feng , REN, Hong , WEISEL, Mark , ZHANG, Siwei , LARPENT, Patrick
IPC分类号： A61K31/505
摘要： Disclosed herein is a novel process for preparing Compound A free base, 5-((2,4-diaminopyrimidin-5-yl)oxy)-4-isopropyl-2-methoxybenzenesulfonamide, and a citrate salt of Compound A with simplified chemistry and a high overall yield: Compound A. In one embodiment, the overall yield from the starting material 2-isopropylphenol to Compound A citrate salt is greater than 50%. In another embodiment, the overall yield is greater than 60%. Also disclosed herein are novel salts and solvates of Compound A.

38. 发明申请

WO2017213944A1 SOLID FORMS OF CEFTOLOZANE AND PROCESSES FOR PREPARING 审中-公开
标题翻译： CEFTOLOZANE的固体形式和制备方法
公开(公告)号：WO2017213944A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/035345
申请日：2017-06-01
申请人： MERCK SHARP & DOHME CORP. , MALONEY, Kevin Matthew , SIROTA, Eric, M. , VARSOLONA, Richard, J. , GAUTHIER, Donald, R., Jr. , REN, Hong
发明人： MALONEY, Kevin Matthew , SIROTA, Eric, M. , VARSOLONA, Richard, J. , GAUTHIER, Donald, R., Jr. , REN, Hong
IPC分类号： C07D417/14
摘要： The instant invention is related to a novel solid form of ceftolozane sulfate (the DMAc solvate of ceftolozane sulfate (Form 3)), compositions comprising ceftolozane sulfate DMAc solvate (Form 3), synthesis of Form 3 and an improved crystallization process using Form 3 to prepare ceftolozane sulfate Form 2. Novel compositions also include ceftolozane sulfate solid Form 3 and/or other crystalline and amorphous solid forms of ceftolozane.
摘要翻译：本发明涉及一种新型固体形式的硫酸头孢菌素（硫酸头孢菌唑硫酸盐的DMAc溶剂化物（形式3）），包含硫酸头孢菌素DMAc溶剂化物的组合物（形式3），形式3的合成和使用形式3改进的结晶过程来制备硫酸头孢菌素硫酸盐形式2.新型组合物还包括硫酸头孢菌素硫酸盐固体形式3和/或其它晶体和无定形固体形式的头孢菌肼（ceftolozane）。

39. 发明申请

WO2007133734A2 DATA OVER SIGNALING (DOS) OPTIMIZATION OVER WIRELESS ACCESS NETWORKS 审中-公开
标题翻译：数据通过无线接入网络进行信令（DOS）优化
公开(公告)号：WO2007133734A2
公开(公告)日：2007-11-22
申请号：PCT/US2007/011531
申请日：2007-05-14
申请人： NORTEL NETWORKS LIMITED , AKHTAR, Haseeb , PILLAI, Krishnakumar , REN, Hong , CAO, Carl
发明人： AKHTAR, Haseeb , PILLAI, Krishnakumar , REN, Hong , CAO, Carl
IPC分类号： A63B22/04
CPC分类号： H04L1/0079
摘要： The present invention supports a communication protocol on a wireless communication network to transmit application data on the control channel to an access terminal. Base transceiver stations are grouped and configured into paging zones. The radio network controller transmits a page message and application data to the base transceiver stations in the paging zone where the access terminal is located. Each of the base transceiver stations transmits a page and buffers the application data. The buffered application data is only transmitted by the base transceiver station receiving a response to the page.
摘要翻译：本发明支持无线通信网络上的通信协议，以将控制信道上的应用数据传送到接入终端。基站收发台被分组并配置成寻呼区域。无线网络控制器将寻呼消息和应用数据发送到接入终端所在的寻呼区中的基站收发台。每个基站收发台发送一个页面并缓冲该应用数据。所缓冲的应用数据仅由接收到对该页的响应的基站发送。

40. 发明申请

WO2004030820A2 METHODS AND APPARATUS FOR MANIPULATING DROPLETS BY ELECTROWETTING-BASED TECHNIQUES 审中-公开
标题翻译：通过电镀技术控制滴定液的方法和装置
公开(公告)号：WO2004030820A2
公开(公告)日：2004-04-15
申请号：PCT/US2003/012754
申请日：2003-04-24
申请人： DUKE UNIVERSITY , PAMULA, Vamsee, K. , POLLACK, Michael, G. , PAIK, Philip, Y. , REN, Hong , FAIR, Richard, B.
发明人： PAMULA, Vamsee, K. , POLLACK, Michael, G. , PAIK, Philip, Y. , REN, Hong , FAIR, Richard, B.
IPC分类号： B01L
CPC分类号： B01L3/50273 , B01F11/0071 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/00 , B01L3/5027 , B01L3/502784 , B01L3/502792 , B01L2200/06 , B01L2200/0605 , B01L2200/10 , B01L2300/089 , B01L2300/161 , B01L2300/165 , B01L2400/0415 , B01L2400/0427 , B41J2002/14395 , C25B9/00 , G01N27/44791 , G02B26/005
摘要： An apparatus is provided for manipulating droplets. The apparatus is a single-sided electrode design in which all conductive elements are contained on one surface on which droplets are manipulated. An additional surface can be provided parallel with the first surface for the purpose of containing the droplets to be manipulated. Droplets are manipulated by performing electrowetting-based techniques in which electrodes contained on or embedded in the first surface are sequentially energized and de-energized in a controlled manner. The apparatus enables a number of droplet manipulation processes, including merging and mixing two droplets together, splitting a droplet into two or more droplets, sampling a continuous liquid flow by forming from the flow individually controllable droplets, and iterative binary or digital mixing of droplets to obtain a desired mixing ratio.
摘要翻译：提供了一种用于操纵液滴的装置。该装置是单面电极设计，其中所有导电元件都包含在其上操作液滴的一个表面上。为了容纳待操作的液滴，可以与第一表面平行地设置另外的表面。通过执行基于电润湿的技术来操纵液滴，其中包含在或嵌入在第一表面中的电极被顺序地通电并以受控的方式断电。该装置能够进行多个液滴操纵过程，包括将两个液滴合并和混合在一起，将液滴分成两个或更多个液滴，通过从流动单独控制的液滴形成连续的液体流，以及液滴的迭代二进制或数字混合到获得所需的混合比。

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