专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2016153915A1 METHOD OF PURIFYING A BIOLOGICAL COMPOSITION AND ARTICLE THEREFOR 审中-公开
标题翻译：净化生物组合物的方法及其制品
公开(公告)号：WO2016153915A1
公开(公告)日：2016-09-29
申请号：PCT/US2016/022842
申请日：2016-03-17
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： VAIL, Andrew W. , RASMUSSEN, Jerald K. , SCHMIDT, John J. , OZCAM, Ali E. , HESTER, Jonathan F. , JELLUM, Gregory M.
IPC分类号： B01D37/00 , C12N5/00 , C12N15/00 , G01N30/00
CPC分类号： C08F255/02 , C08F220/00 , C12N15/101 , C12N15/1017 , C12Q1/6806 , D06M14/00 , G01N1/4077 , G01N2001/4088
摘要： A method of purifying a biological composition includes: disposing loose cationic ligand-functionalized staple fibers and a biological composition within a mixing volume of a vessel; agitating the biological composition and the loose cationic ligand-functionalized staple fibers while they are in intimate contact with each other within the mixing volume to provide modified fibers and a purified biological composition; and separating at least a portion of the purified biological composition from the modified fibers and any loose cationic ligand-functionalized staple fibers with which it is in contact. The loose cationic ligand-functionalized staple fibers have a modified surface layer comprising a grafted acrylic polymer comprising 10 to 100 percent by weight of a cationically-ionizable monomer unit. An article for purifying a biological composition includes: a vessel having a mixing volume disposed therein; and the loose cationic ligand-functionalized staple fibers disposed within the mixing volume.
摘要翻译：纯化生物组合物的方法包括：将松散的阳离子配体官能化短纤维和生物组合物置于容器的混合体积中; 搅拌生物组合物和松散的阳离子配体官能化短纤维，同时在混合体积内彼此紧密接触以提供改性纤维和纯化的生物组合物; 并将纯化的生物组合物的至少一部分与改性纤维和与其接触的任何松散的阳离子配体官能化短纤维分离。松散的阳离子配体官能化短纤维具有包含接枝丙烯酸聚合物的改性表面层，其包含10至100重量％的阳离子可离子化单体单元。用于纯化生物组合物的制品包括：其中设置有混合体积的容器; 以及布置在混合体积内的松散的阳离子配体官能化短纤维。

32. 发明申请

WO2008014137A1 METHOD OF MAKING MACROPOROUS CATION EXCHANGE RESINS 审中-公开
标题翻译：制造大面积交换树脂的方法
公开(公告)号：WO2008014137A1
公开(公告)日：2008-01-31
申请号：PCT/US2007/073571
申请日：2007-07-16
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RASMUSSEN, Jerald K. , FITZSIMONS, Robert T. Jr. , SESHADRI, Kannan , SHANNON, Simon K. , WICKERT, Peter D. , HEMBRE, James I.
IPC分类号： C08J9/00 , C08J5/20 , C08F2/32 , B01J39/20
CPC分类号： C08F2/32 , B01D15/362 , B01J39/20 , B01J39/26 , C08F2/20 , C08J5/2231 , C08J2333/26 , Y10T428/249953
摘要： Methods of making macroporous cation exchange resins are described. The macroporous cation exchange resins are in the form of particles such as beads that contain a hydrophilic, crosslinked, (meth)acrylic-type polymeric material. The macroporous cation exchange resins are prepared using an inverse suspension polymerization process in the presence of a water soluble, organic, aliphatic porogen having at least three hydroxy groups.
摘要翻译：描述了制备大孔阳离子交换树脂的方法。大孔阳离子交换树脂是含有亲水交联的（甲基）丙烯酸类聚合物材料的颗粒如珠粒的形式。在具有至少三个羟基的水溶性有机脂族致孔剂存在下，使用反相悬浮聚合方法制备大孔阳离子交换树脂。

33. 发明申请

WO2023084369A1 METHOD OF PROCESSING POLYNUCLEIC ACIDS 审中-公开
公开(公告)号：WO2023084369A1
公开(公告)日：2023-05-19
申请号：PCT/IB2022/060640
申请日：2022-11-04
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： WATTS, Annabelle , BONILLA, Tonya D. , RASMUSSEN, Jerald K. , FISHMAN, Joshua M. , TRAEGER, Lindsay L. , COLAK ATAN, Semra
IPC分类号： C12N15/10 , C12Q1/6806 , C12Q1/6813
摘要： A method of processing polynucleic acids is described comprising: providing a solid support comprising ligands with an amide group; exposing the solid support to polynucleic acid molecules in a buffer having a pH less than 5.5 to bind at least a portion of the polynucleic acid molecules to the ligands; c) exposing the solid support (e.g. particles) with bound polynucleic acid molecules to a buffer having a pH greater than 6 to release a portion of the bound polynucleic acid molecules from the ligands of the particles and to retain a portion of the polynucleic acid molecules bound to the solid support (e.g. particles); and utilizing the solid support with retained bound polynucleic acid molecules or suspension thereof.

34. 发明申请

WO2021209851A1 FLOW-THROUGH PROCESSES AND DEVICES FOR PURIFYING A TARGET MOLECULE 审中-公开
公开(公告)号：WO2021209851A1
公开(公告)日：2021-10-21
申请号：PCT/IB2021/052739
申请日：2021-04-01
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： VAIL, Andrew W. , ATAN, Semra C. , RASMUSSEN, Jerald K. , VOLOSHIN, Alexei M. , HESTER, Jonathan F.
IPC分类号： C07K1/18 , C07K1/36
摘要： Flow-through processes for purifying a target molecule (e.g., antibodies, enzymes, and hormones, particularly a monoclonal antibody) from a biological solution (e.g., a neutralized viral inactivation pool) in a sample that includes the target molecule, and devices for carrying out such processes.

35. 发明申请

WO2021105864A1 METHOD FOR BIOMATERIAL PURIFICATION AND KITS THEREOF 审中-公开
公开(公告)号：WO2021105864A1
公开(公告)日：2021-06-03
申请号：PCT/IB2020/061072
申请日：2020-11-24
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RICHARDSON, Kristopher E. , O'NEAL, Daniel J. , RASMUSSEN, Jerald K. , VAIL, Andrew W.
IPC分类号： C07K1/32 , C07K1/34
摘要： Described herein is a method of purifying a target molecule from an aqueous biological composition, the method comprising: (a) contacting a cationic polymer and the aqueous biological composition to form a mixture comprising a bio-polymer complex and the target molecule in a liquid, wherein the bio-polymer complex has an average particle diameter of at least 45 micrometers, (b) adding the mixture to a filtering volume of a vessel, wherein the vessel comprises loosely packed staple fibers; (c) allowing the mixture to separate through the loosely packed staple fiber; and (d) collecting a filtrate comprising the target molecule.

36. 发明申请

WO2021105843A1 BIOTIN-CONTAINING MONOMERS AND ARTICLES FORMED THEREFROM 审中-公开
公开(公告)号：WO2021105843A1
公开(公告)日：2021-06-03
申请号：PCT/IB2020/061018
申请日：2020-11-23
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RASMUSSEN, Jerald K.
IPC分类号： C08F220/54 , C09D4/00 , C09D133/24
摘要： Biotin-containing monomers, polymeric materials formed from the biotin-containing monomers, articles containing the polymeric materials, methods of making the articles, and methods of using the articles are provided. The articles can be used, for example, for affinity capture of biotin-binding proteins, including biotin-binding fusion proteins (i.e., a biotin-binding protein fused to another biomaterial). Articles that contain captured biotin-binding proteins can be further used for affinity capture of various biotin-containing biomaterials such as biotinylated proteins. The articles can also be used, for example, for affinity capture of biotin-binding fusion proteins where the fusion protein includes, for example, an enzyme or antibody.

37. 发明申请

WO2018048698A1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION 审中-公开
标题翻译：在生物溶液中从单体蛋白中分离聚集蛋白的过程
公开(公告)号：WO2018048698A1
公开(公告)日：2018-03-15
申请号：PCT/US2017/049376
申请日：2017-08-30
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： COLAK ATAN, Semra , VAIL, Andrew W. , RASMUSSEN, Jerald K. , GRIESGRABER, George W. , BOTHOF, Catherine A.
IPC分类号： C07K1/18 , C07K1/34
CPC分类号： C07K1/34 , B01D71/40 , C07K1/18 , C07K16/00
摘要： A process for separating aggregated proteins from monomeric proteins in a biological solution, the process including: providing at least one filter element having a contacting surface, wherein the filter element comprises filter media comprising: a porous substrate; and disposed on the porous substrate, a polymer comprising a hydrocarbon backbone and a plurality of pendant groups attached to the hydrocarbon backbone, wherein each of a first plurality of pendant groups comprises: (1) at least one acidic group or salt thereof; and (2) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and allowing an initial biological solution to contact the contacting surface of the filter element under conditions effective to separate the aggregated proteins from the monomeric proteins such that a final biological solution includes purified monomeric proteins.
摘要翻译：一种用于从生物溶液中的单体蛋白中分离聚集蛋白的方法，所述方法包括：提供至少一个具有接触表面的过滤元件，其中所述过滤元件包含过滤介质，所述过滤介质包含：多孔基材; 并且设置在所述多孔基材上的聚合物，所述聚合物包含烃骨架和连接至所述烃骨架的多个侧基，其中第一多个侧基中的每一个包含：（1）至少一种酸性基团或其盐; 和（2）通过至少6个连接原子的链将所述至少一个酸性基团或其盐直接连接到烃主链上的间隔基团; 并且在有效将聚集蛋白与单体蛋白分离的条件下使初始生物溶液与过滤元件的接触表面接触，使得最终生物溶液包括纯化的单体蛋白。

38. 发明申请

WO2016149303A1 COALESCING ELEMENTS IN COPPER PRODUCTION 审中-公开
标题翻译：铜生产中的加工元素
公开(公告)号：WO2016149303A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022543
申请日：2016-03-16
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： WALLER, Clinton P., Jr. , JARIWALA, Chetan P. , RASMUSSEN, Jerald K. , SCHMIDT, John J. , SIERAKOWSKI, Michael J. , WEILANDT, Karl D.
IPC分类号： C22B15/14 , B01D17/022 , C22B3/06
CPC分类号： C22B15/0086 , B01D17/045 , C22B3/0005 , C22B15/0065 , C22B15/0071 , Y02P10/234 , Y02P10/236
摘要： A coalescing element for aggregating droplets of an emulsion. The coalescing element includes a nonwoven web substrate. A coalescer that includes the coalescing element can also include a housing and a fluid inlet and a fluid outlet each in fluid communication with the coalescing element. The coalescing element and coalescer may be useful for emulsions that form in solvent extraction/electowinning copper processing and for other emulsions.
摘要翻译：用于聚集乳液液滴的聚结元件。聚结元件包括非织造纤网基材。包括聚结元件的聚结器还可以包括壳体和每个与聚结元件流体连通的流体入口和流体出口。聚结元件和聚结器可用于在溶剂萃取/电渗铜处理和其它乳液中形成的乳液。

39. 发明申请

WO2015200157A1 ABSORBENT ARTICLES AND METHODS OF MAKING 审中-公开
标题翻译：吸收文章和制作方法
公开(公告)号：WO2015200157A1
公开(公告)日：2015-12-30
申请号：PCT/US2015/036869
申请日：2015-06-22
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RASMUSSEN, Jerald K. , ALI, Mahfuza B. , CHONG CONKLIN, Bathsheba E. , KLEIN, Andrew P. , LANGER, Scott E.
IPC分类号： A61L15/42 , A61L15/60
CPC分类号： A61L15/425 , A61L15/24 , A61L15/60 , B01J20/267 , B01J20/3071 , B01J20/327 , C08J9/28 , C08J2201/046 , C08J2333/02
摘要： Described herein are absorbent articles and methods of making such articles. The articles are made by bonding a copolymer onto a substrate to form a core. The absorbent articles are particularly useful in personal care product, e.g., disposable hygiene products.
摘要翻译：这里描述的是制造这种制品的吸收制品和方法。制品通过将共聚物粘合到基材上以形成核心而制成。吸收制品特别适用于个人护理产品，例如一次性卫生产品。

40. 发明申请

WO2014204763A1 PROCESS FOR PREPARING GUANIDINO-FUNCTIONAL MONOMERS 审中-公开
标题翻译：制备官能单体的方法
公开(公告)号：WO2014204763A1
公开(公告)日：2014-12-24
申请号：PCT/US2014/042028
申请日：2014-06-12
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RASMUSSEN, Jerald K. , GRIESGRABER, George W. , HEMBRE, James I.
IPC分类号： C07C277/08 , C07C277/02 , C07C279/12 , C08G69/00 , C08G73/00 , C09D177/00 , C09D179/02 , B01D71/60 , B01J20/26 , D06M14/30 , G01N33/53
CPC分类号： C07C277/08 , B01J20/261 , B01J20/28033 , B01J20/327 , C07C277/02 , C07C279/12 , C08F26/00 , C08F120/36 , C08F126/02 , C08F220/36 , C09D4/00 , C09D133/14 , D06M14/30 , G01N1/405 , G01N33/53 , G01N33/545 , C07C279/08
摘要： A process for preparing guanidino-functional, free radically polymerizable compounds comprises (a) combining (1) an amine compound comprising (i) at least one primary aliphatic amino group and (ii) at least one secondary aliphatic amino group, primary aromatic amino group, or secondary aromatic amino group, and (2) a guanylating agent; (b) allowing or inducing reaction of the amine compound and the guanylating agent to form a guanylated amine compound; (c) combining (1) the guanylated amine compound, and (2) a reactive monomer comprising (i) at least one ethylenically unsaturated group and (ii) at least one group that is reactive with an amino group; and (d) allowing or inducing reaction of the guanylated amine compound and the reactive monomer to form a guanidino-functional, free radically polymerizable compound.
摘要翻译：制备胍基官能的可自由基聚合化合物的方法包括（a）将（1）胺化合物（i）至少包含一个伯脂肪族氨基和（ii）至少一个仲脂肪族氨基，伯芳族氨基或仲芳族氨基，和（2）脒基化剂; （b）允许或诱导胺化合物和脒基化剂反应形成胍化胺化合物; （c）将（1）胍化胺化合物和（2）包含（i）至少一种烯属不饱和基团和（ii）至少一个与氨基反应的基团的反应性单体的组合; 和（d）允许或诱导胍化胺化合物和反应性单体的反应以形成胍基官能的可自由基聚合的化合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式