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    • 21. 发明申请
    • CONTROL OF PHOTOREFRACTIVE KERATECTOMY
    • 控制光电性质
    • WO1995027534A1
    • 1995-10-19
    • PCT/US1995004042
    • 1995-04-07
    • SUMMIT TECHNOLOGY, INC.
    • SUMMIT TECHNOLOGY, INC.MULLER, David, F.SACHAROFF, Alex, C.KLOPOTEK, Peter, J.
    • A61N05/02
    • A61F9/008A61B90/30A61B2017/00017A61B2017/00176A61B2017/00181A61B2017/00194A61F9/00804A61F9/00808A61F2009/00844A61F2009/00848A61F2009/00872A61F2009/00895
    • A method and system are described for performing photorefractive keratectomy, a desired refractive correction in the corneal tissue. The method and system employ control (32) of the effect of ocular fluid at the corneal surface so as to reduce the disturbance of such fluid on the desired ablation process while maintaining hydration of the corneal tissue. Controlling the average repetition rate (26) of the radiation pulses (24) applied to the corneal surface so as to reduce intrapulse fluid accumulation at the corneal surface without dehydrating the corneal tissue, selecting an increased fluence level of the pulse applied to the corneal surface to reduce the effect of fluid accumulation at the corneal surface, and applying evaporative energy to the site of incidence of a pulse of an ablative beam prior to incidence of said pulse at said site are shown as ways to effect this control. Application of the new method and system to wide area ablation techniques and to scanning techniques are described.
    • 描述了用于进行光折射角膜切除术,角膜组织中期望的屈光矫正的方法和系统。 该方法和系统采用对角膜表面的眼液的影响的控制(32),以便在保持角膜组织水合的同时减少所需消融过程中的这种流体的干扰。 控制施加到角膜表面的辐射脉冲(24)的平均重复率(26),以减少角膜表面的脉冲内液体积聚,而不会使角膜组织脱水,选择增加到角膜表面的脉冲的注量水平 以减少在角膜表面的液体积聚的影响,并且在所述位置处的所述脉冲入射之前将消耗能量施加到烧蚀光束的脉冲的入射部位被示出为实现该控制的方式。 描述了新方法和系统对广域消融技术和扫描技术的应用。
    • 23. 发明申请
    • URETHRAL INSERTED APPLICATOR FOR PROSTATE HYPERTHERMIA
    • URETHRAL插入式应用程序用于前瞻性高血压
    • WO1993008876A1
    • 1993-05-13
    • PCT/US1991008137
    • 1991-11-04
    • BSD MEDICAL CORPORATION
    • BSD MEDICAL CORPORATIONTURNER, Paul, F.ASTRAHAN, Melvin, Alan
    • A61N05/02
    • A61B18/1815A61B18/18A61B2018/00166A61B2018/1861A61M2025/0177
    • A urethral inserted applicator for prostate electromagnetic hyperthermia includes apparatus for holding and positioning at least one electromagnetic energy applicator (14) in a urethral passage extending through a prostate gland. The apparatus includes a multipassage or multitube, balloon type urinary or Foley catheter (18) with fluid-dry passages for insertion of microwave antenna or capacitive electrode type applicators (14), and an electromagnetic compatible type temperature sensor (25) for measuring the temperature of the prostate tissue. The urinary catheter provides an open fluid receiving tube (56) enabling urine drainage from the bladder and a balloon (76) at the tip region of the catheter for engaging the bladder neck to properly position and hold the apparatus during treatment. An electromagnetic generator (12) supplies electromagnetic energy to the applicators (14). A comparator (42) is connected to the temperature sensor (25) and a temperature reference potentiometer (44) for comparing the actual tissue temperature with a desired temperature and for providing output control signals to the electromagnetic generator (12) for controlling the output of the generator to the applicators (14).
    • 用于前列腺电磁疗法的尿道插入施用器包括用于保持和定位延伸穿过前列腺的尿道中的至少一个电磁能量施加器(14)的装置。 该装置包括具有用于插入微波天线或电容电极型施加器(14)的流体干燥通道的多通道或多管气囊型尿液或Foley导管(18),以及用于测量温度的电磁兼容型温度传感器(25) 的前列腺组织。 导尿管提供开放的液体接收管(56),使得尿液从膀胱排出,并且在导管的尖端区域处具有气囊(76),用于接合膀胱颈部,以在治疗期间适当地定位和保持装置。 电磁发生器(12)向施用器(14)供应电磁能。 比较器(42)连接到温度传感器(25)和用于将实际组织温度与期望温度进行比较的温度参考电位器(44),并且用于向电磁发生器(12)提供输出控制信号,以控制 发电机到施加器(14)。
    • 26. 发明申请
    • INSTRUMENT AND METHOD FOR INTRALUMINALLY RELIEVING STENOSIS
    • 用于治疗STENOSIS的仪器和方法
    • WO1990013333A1
    • 1990-11-15
    • PCT/US1990002285
    • 1990-04-26
    • INTRA-SONIX, INC.
    • INTRA-SONIX, INC.ROTH, Robert, A.MARTINELLI, Michael, A.
    • A61N05/02
    • A61B18/24A61B2017/00274A61B2017/22059A61B2018/00547A61B2090/3784A61M25/104A61M29/02
    • An instrument for and method of effectively dilating a stenotic region of a passageway of a portion of the living body, preferably the prostatic urethra, so as to relieve the symptoms associated with the stenosis. In the preferred system the tissue of at least selected portions of the prostate (172) are compressed (preferably with a balloon (8) inserted into the prostatic urethra so as to enhance hemostasis), and at least selected portions of the compressed tissue are denatured (preferably with a laser beam transmitted from within the passageway in selected radial directions) so that as the denatured tissue heals, the denatured tissue tends to shrink so as to effectively dilate the portions of the prostatic urethra. Ultrasonic transducers are used from within the prostatic urethra to image the tissue as it is denatured so as to monitor the procedure to insure proper exposure to the laser beam.
    • 用于有效扩张生物体的一部分通道的狭窄区域,优选前列腺尿道的仪器和方法,以便减轻与狭窄有关的症状。 在优选的系统中,前列腺(172)的至少选定部分的组织被压缩(优选用插入前列腺尿道的气囊(8)以增强止血),并且至少压缩组织的选定部分变性 (优选地具有在选定的径向方向上从通道内传递的激光束),使得当变性组织愈合时,变性组织倾向于收缩,以有效地扩张前列腺尿道的部分。 超声波换能器在前列腺尿道内使用,以便在组织变性时对组织进行成像,以便监视程序以确保适当地暴露于激光束。
    • 28. 发明申请
    • SYSTEM FOR IRRADIATING LIVING TISSUE,OR SIMULATION THEREOF
    • 用于照射生活组织或其模拟的系统
    • WO1980001462A1
    • 1980-07-24
    • PCT/US1980000008
    • 1980-01-07
    • BSD CORP
    • BSD CORPTURNER P
    • A61N05/02
    • A61N5/02A61N5/04
    • System (10) for irradiating living bodies or portions thereof, using electromagnetic radiation. A source or generator (18) provides electromagnetic energy at a selected frequency within an operational band width, via a coaxial cable (22) to an applicator (20) for radiation into living tissue (12). The source (18), cable (22), and applicator (20) each have a characteristic impedance approximately equal to the average impedance of the living tissue (12) over a broad frequency band, thus enabling efficient operation of the apparatus (10) without using auxiliary impedance matching devices. The applicator (20) is of a waveguide transmission line type (96) enabling efficient transmission and radiation of the electromagnetic energy and further incorporates means (58) for cooling surface portions (24) of the living tissue (12) during radiation thereof. Selective dielectric loading (114, 116, 118, 120 + 122) is provided. A feedback control system (28) including temperature sensors (34, 36 + 38) placed onto or into the tissue (12) enables the control of tissue surface and subsurface temperatures within a preselected range by adjusting the power level of the generator (18).
    • 用于使用电磁辐射照射活体或其部分的系统(10)。 源或发生器(18)通过同轴电缆(22)将工作带宽内的选定频率的电磁能量提供给施加器(20),用于辐射进入生物体组织(12)。 源极(18),电缆(22)和施加器(20)各自具有近似等于在宽频带上的生物体组织(12)的平均阻抗的特性阻抗,从而使得装置(10)能够有效地操作, 不使用辅助阻抗匹配装置。 施加器(20)具有能够有效地传输和辐射电磁能的波导传输线类型(96),并且还包括用于在其辐射期间冷却活组织(12)的表面部分(24)的装置(58)。 提供选择性介电负载(114,116,118,120 + 122)。 包括放置在组织(12)上或组织(12)上的温度传感器(34,36 + 38)的反馈控制系统(28)使得能够通过调节发电机(18)的功率水平来控制预选范围内的组织表面和地下温度, 。
    • 29. 发明申请
    • APPARATUS AND METHOD FOR PERFORMING LASER THERMAL KERATOPLASTY WITH MINIMIZED REGRESSION
    • 具有最小化回归的激光热应激的装置和方法
    • WO1998019741A1
    • 1998-05-14
    • PCT/US1997018823
    • 1997-10-21
    • HUANG, DavidMcDONNELL, Peter, J.
    • A61N05/02
    • A61F9/008A61F2009/00853A61F2009/00872
    • This invention is a non-contact apparatus and method for performing laser thermal keratoplasty capable of scanning of treatment areas with shapes that reduce regression. The apparatus includes laser sources (70, 78, 40), a projection optical system, observation system, and control system. The projection system uses two steering mirrors (56, 58) to control laser beam position on the cornea. This projection system enables precise control of the area of corneal heat shrinkage using relatively low-powered lasers, such as diode lasers. Desired changes in corneal refractive power are produced by selected patterns of photothermal shrinkage of corneal collagen tissue. The selected patterns are arrangements of oblong shapes that are preferably tapered at the ends of the long axis. The oblong shape and tapering distribute tension in the cornea over a wider area of collagen shrinkage and improve the stability of refractive correction. The long axes of the oblong treatment areas are preferably oriented radially for hyperopia correction and circumferentially for astigmatism correction.
    • 本发明是一种用于进行能够扫描具有减少回归形状的治疗区域的激光热角膜移植术的非接触式装置和方法。 该装置包括激光源(70,78,40),投影光学系统,观察系统和控制系统。 投影系统使用两个转向镜(56,58)来控制角膜上的激光束位置。 该投影系统能够使用诸如二极管激光器的相对低功率的激光器来精确地控制角膜热收缩的面积。 角膜屈光力的期望变化由角膜胶原组织的光热收缩的选择图案产生。 所选择的图案是长轴形状的布置,其优选在长轴的端部处是锥形的。 椭圆形和锥形分布在角膜的更大面积的胶原收缩中分布张力,并提高屈光矫正的稳定性。 长圆形处理区域的长轴优选径向地进行远视校正,并且周向地用于散光校正。
    • 30. 发明申请
    • VOLTAGE CONTROLLED VARIABLE TUNING ANTENNA
    • 电压控制可变调谐天线
    • WO1997035639A1
    • 1997-10-02
    • PCT/US1997005066
    • 1997-03-26
    • UROLOGIX, INC.
    • UROLOGIX, INC.RUDIE, Eric, N.
    • A61N05/02
    • A61B18/18A61B18/1815
    • A catheter shaft (32) carries a coaxial cable (76), the terminal end of which contains a dipole antenna (74) with opposing first and second helical elements (142, 144). The first and second helical elements (142, 144) originate from a common connection to an outer conductor (124) of the coaxial cable (76). The first and second helical elements (142, 144) are formed by winding flat wire (140) around an outer insulator (126) of the coaxial cable (76) near a terminal end of the coaxial cable (76). A variable, controllable impedance (128, 202) is connected between an inner conductor (120) of the coaxial cable (76) and a point on the second helical element (144) where the resistive component of the antenna's impedance matches the characteristic impedance of the coaxial cable (76). The impedance match minimizes reflective losses of the antenna (74), thereby maximizing power transferred to the antenna (74). The antenna (74) has an effective electrical length which is equal to one-half the wavelength of the radiation emitted, independent of the physical length of the antenna. The antenna (74) also has a radiation length which can be adjusted by varying the number in pitch and turns of the flat wire (140) and the location of the impedance matching point.
    • 导管轴(32)承载同轴电缆(76),其同轴电缆(76)的终端包含具有相对的第一和第二螺旋元件(142,144)的偶极天线(74)。 第一和第二螺旋元件(142,144)源自与同轴电缆(76)的外部导体(124)的公共连接。 第一和第二螺旋元件(142,144)通过在同轴电缆(76)的终端附近围绕同轴电缆(76)的外绝缘体(126)缠绕扁平线(140)而形成。 可变的可控阻抗(128,202)连接在同轴电缆(76)的内导体(120)和第二螺旋元件(144)上的点之间,其中天线阻抗的电阻分量与 同轴电缆(76)。 阻抗匹配使天线(74)的反射损耗最小化,从而使传递到天线(74)的功率最大化。 天线(74)具有等于发射的辐射的波长的一半的有效电长度,与天线的物理长度无关。 天线(74)还具有可以通过改变扁平线(140)的间距和匝数以及阻抗匹配点的位置来调节的辐射长度。