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21. 发明申请

WO2015131234A1 A METHOD FOR PRODUCING A CUSTOMISED ORTHOPAEDIC IMPLANT 审中-公开
标题翻译：用于生产定制的正交植入物的方法
公开(公告)号：WO2015131234A1
公开(公告)日：2015-09-11
申请号：PCT/AU2015/000124
申请日：2015-03-04
申请人： RMIT UNIVERSITY
发明人： SHIDID, Darpan , LEARY, Martin , BRANDT, Milan , CHOONG, Peter
IPC分类号： A61F2/28 , A61F2/30 , B29C67/00 , A61B17/56
CPC分类号： A61F2/30942 , A61F2/28 , A61F2002/30006 , A61F2002/30011 , A61F2002/30014 , A61F2002/30263 , A61F2002/3092 , A61F2002/3093 , A61F2002/30948 , A61F2002/30952 , A61F2002/30962 , A61F2002/3097 , A61F2002/30985 , B29C64/153 , B29L2031/7532 , B33Y10/00 , B33Y50/00 , B33Y80/00
摘要： A method for producing a customised orthopaedic implant is provided. The method involves scanning a bone from which a diseased region of bone will be resected to obtain a three dimensional digital image of an unresected volume of bone; scanning the bone after a diseased region of bone has been resected to obtain a corresponding three dimensional digital image of a resected volume of bone; and comparing the three dimensional digital image of the unresected volume of bone to the corresponding three dimensional digital image of the resected volume of bone to estimate a volume of bone that has been resected. The estimate of the volume of bone that has been resected is used to design a customised orthopaedic implant that substantially corresponds to the configuration of the resected volume of bone, the implant being configured to substantially restore a biomechanical function of the bone. Finally the customised orthopaedic implant is manufactured and provided for insertion into the resected region of bone.
摘要翻译：提供了一种用于生产定制的矫形植入物的方法。该方法包括扫描骨头，从其中切除患病区域以获得未切割体积的骨的三维数字图像; 在切除了患病区域之后扫描骨，以获得切除体积的骨的相应的三维数字图像; 并将未切割体积的骨的三维数字图像与切除的骨量的相应三维数字图像进行比较，以估计已被切除的骨的体积。已经切除的骨的体积的估计用于设计基本上对应于骨的切除体积的构造的定制的整形外科植入物，植入物被配置为基本上恢复骨的生物力学功能。最后，制造并提供定制的矫形植入物用于插入到骨的切除区域中。

22. 发明申请

WO2015010223A1 一种个性化椎间盘人工髓核假体制造装置及方法审中-公开
公开(公告)号：WO2015010223A1
公开(公告)日：2015-01-29
申请号：PCT/CN2013/001250
申请日：2013-10-15
申请人：林杨 , 曹汉辉
发明人：林杨 , 曹汉辉 , 张忠峰 , 付源博 , 高瑾 , 林均利 , 董长和
IPC分类号： A61F2/44
CPC分类号： A61F2/30942 , A61F2/44 , A61F2002/30293 , A61F2002/30948 , A61F2002/30985 , A61F2002/444
摘要：一种个性化椎间盘人工髓核假体制造装置和方法，该装置包括信息采集仪（1）、中央处理器（2）和3D打印机（3），信息采集仪（1）通过中央处理器（2）和3D打印机（3）相连接，3D打印机（3）的打印头装有医用高分子材料；制造出的人工髓核假体（4）为长条状，宽度为2-6m，厚度为5-9m，整体外观呈盘旋状态，盘旋后的外形尺寸为纵向直径为8-22m，横向直径为18-38m。该装置根据不同患者的髓核尺寸个性化制作出符合要求的人工髓核假体，用于治疗腰椎间盘病，克服了现有的人工髓核假体只能制作出固定的几种规格、不能满足实际需要的问题，解决了因为人工髓核假体尺寸不符导致的盘内不稳、移位等问题。

23. 发明申请

WO2014209604A1 VERTEBRAL BODY REPLACEMENT APPARATUS 审中-公开
标题翻译： VERTEBRAL身体替代装置
公开(公告)号：WO2014209604A1
公开(公告)日：2014-12-31
申请号：PCT/US2014/041830
申请日：2014-06-11
申请人： DEPUY SYNTHES PRODUCTS, LLC
发明人： POPA, Samantha , RANDEGGER, Roman , OVERES, Tom
IPC分类号： A61F2/44 , A61F2/30 , A61F2/28
CPC分类号： A61F2/446 , A61F2/30744 , A61F2/30767 , A61F2/30965 , A61F2/44 , A61F2/442 , A61F2002/2835 , A61F2002/30006 , A61F2002/30062 , A61F2002/30235 , A61F2002/30405 , A61F2002/30433 , A61F2002/30471 , A61F2002/30476 , A61F2002/30495 , A61F2002/30497 , A61F2002/3055 , A61F2002/30563 , A61F2002/30566 , A61F2002/30571 , A61F2002/30578 , A61F2002/30594 , A61F2002/30601 , A61F2002/30616 , A61F2002/30784 , A61F2002/30841 , A61F2002/30878 , A61F2002/30925 , A61F2002/30957 , A61F2002/3098 , A61F2002/30985 , A61F2002/4475 , A61F2310/00011 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00359 , A61F2310/00407 , A61F2310/00461 , A61F2310/00796
摘要： A vertebral body replacement apparatus includes an outer body member (102) having a first end (110), a second end (112), and an opening (118), and an inner body member (104) having a first end (140), a second end (142), and an inner surface (146) defining an opening (148). The first end (140) of the inner body member (104) is received in the opening (118) of the outer body member (102) such that the inner body member (104) and the outer body member (102) are movable relative to one another. A support member (106) has a first end (160) secured within the inner body member (104) and a second end (142) extending a distance beyond the inner body member (104). The second end (162) of the support member (106) deflects relative to the first end (110) of the outer body member (102) in response to a force applied thereto and returns to a substantially non-deflected condition upon release of the force.
摘要翻译：椎体置换装置包括具有第一端（110），第二端（112）和开口（118）的外主体构件（102）和具有第一端（140）的内主体构件（104），第二端（142）和限定开口（148）的内表面（146）。内本体构件（104）的第一端（140）被容纳在外主体构件（102）的开口（118）中，使得内主体构件（104）和外主体构件（102）相对移动彼此。支撑构件（106）具有固定在内主体构件（104）内的第一端（160）和延伸超过内主体构件（104）的距离的第二端（142）。支撑构件（106）的第二端（162）响应于施加到其上的力而相对于外主体构件（102）的第一端（110）偏转，并且在松开力。

24. 发明申请

WO2013181375A1 TISSUE REPAIR DEVICES AND SCAFFOLDS 审中-公开
标题翻译：组织维修设备和组织
公开(公告)号：WO2013181375A1
公开(公告)日：2013-12-05
申请号：PCT/US2013/043336
申请日：2013-05-30
申请人： NEW YORK UNIVERSITY
发明人： RICCI, John, L. , CLARK, Elizabeth , COELHO, Paulo , VAN THOMPSON, Dianne, Rekow , SMAY, James
IPC分类号： A61L27/56 , A61F2/02 , A61F2/28 , A61L27/54
CPC分类号： A61F2/28 , A61F2/2875 , A61F2/3094 , A61F2002/2817 , A61F2002/30011 , A61F2002/30235 , A61F2002/30574 , A61F2002/3092 , A61F2002/30962 , A61F2002/30968 , A61F2002/30985 , A61F2310/00179 , A61L27/025 , A61L27/54 , A61L27/56 , A61L2430/02 , B33Y80/00
摘要： The present invention relates to multiphasic, three-dimensionally printed, tissue repair devices or scaffolds useful for promoting bone growth and treating bone fracture, defect or deficiency, methods for making the same and methods for promoting bone growth and treating bone fracture, defect or deficiency using the same. The scaffold has a porous bone ingrowth area containing interconnected struts surrounded by a microporous shell. At the ends of the scaffold, the shell may be extended as a guide flange to stabilize the scaffold between ends of bone. The center of the scaffold may be empty and may serve as a potential marrow space. The porous ingrowth structure may be infiltrated with a soluble filler or carrier, such as, for example calcium sulfate which may be infiltrated with one or more of an antibiotic, a growth factor, a differentiation factors, a cytokine, a drug, or a combination of these agents.
摘要翻译：本发明涉及可用于促进骨生长和治疗骨折，缺陷或不足的多相，三维印刷的组织修复装置或支架，其制备方法以及用于促进骨生长和治疗骨折，缺陷或缺陷的方法使用相同支架具有包含由微孔壳包围的相互连接的支柱的多孔骨向内生长区域。在支架的端部，壳可以作为引导凸缘延伸，以在骨的端部之间稳定支架。脚手架的中心可能是空的，可以作为潜在的骨髓空间。多孔向内生长结构可以用可溶性填料或载体渗透，例如硫酸钙，其可以用抗生素，生长因子，分化因子，细胞因子，药物或组合中的一种或多种渗透的这些药剂。

25. 发明申请

WO2012141790A1 PATIENT SPECIFIC JOINT PROSTHESIS 审中-公开
标题翻译：患者特异性联合检查
公开(公告)号：WO2012141790A1
公开(公告)日：2012-10-18
申请号：PCT/US2012/025953
申请日：2012-02-21
申请人： SYNTHES USA, LLC , SYNTHES GMBH , NARDINI, Reto , GLAUSER, Adrian , KASSI, Jean-Pierre
发明人： NARDINI, Reto , GLAUSER, Adrian , KASSI, Jean-Pierre
IPC分类号： A61F2/30 , A61F2/34 , A61F2/40
CPC分类号： A61F2/30734 , A61F2/30942 , A61F2/34 , A61F2/4081 , A61F2002/30736 , A61F2002/3092 , A61F2002/30948 , A61F2002/30952 , A61F2002/30985
摘要： A patient-specific implant includes (a) a body having a convex exterior surface configured to attach to a bone and a concave interior surface configured to receive a head portion of another bone, the body including a plurality of holes extending therethrough, the holes sized and shaped to receive a bone fixation element; and (b) a gap filler formed on the exterior surface of the body and having dimensions and a position corresponding to a gap between the exterior surface of the body and the bone to which the implant is to be attached.
摘要翻译：特定于患者的植入物包括（a）具有构造成附接到骨的凸形外表面的身体和被构造成接收另一骨头的部分的凹内表面，所述主体包括穿过其延伸穿过的多个孔，并且成形为容纳骨固定元件; 和（b）形成在所述主体的外表面上的间隙填料，并且具有尺寸和对应于所述主体的外表面与待附着所述植入物的骨之间的间隙的位置。

26. 发明申请

WO2011156510A3 IMPLANT COMPONENTS AND METHODS 审中-公开
标题翻译：植入组件和方法
公开(公告)号：WO2011156510A3
公开(公告)日：2012-04-19
申请号：PCT/US2011039658
申请日：2011-06-08
申请人： SMITH & NEPHEW INC , CONWAY JUSTIN STEVE , LANDON RYAN L , SHEA JEFFREY JOEL
发明人： CONWAY JUSTIN STEVE , LANDON RYAN L , SHEA JEFFREY JOEL
IPC分类号： A61F2/30 , A61L27/14 , A61L27/56 , B29C44/12
CPC分类号： A61F2/34 , A61B17/8066 , A61B17/82 , A61B17/866 , A61B17/8685 , A61F2/30734 , A61F2/30749 , A61F2/30771 , A61F2/30907 , A61F2/30942 , A61F2/30965 , A61F2/4609 , A61F2002/30011 , A61F2002/30013 , A61F2002/30169 , A61F2002/30189 , A61F2002/30326 , A61F2002/3038 , A61F2002/30387 , A61F2002/30449 , A61F2002/30462 , A61F2002/30471 , A61F2002/30474 , A61F2002/30507 , A61F2002/30538 , A61F2002/30578 , A61F2002/30579 , A61F2002/30604 , A61F2002/30611 , A61F2002/30617 , A61F2002/30736 , A61F2002/3082 , A61F2002/30841 , A61F2002/30891 , A61F2002/3092 , A61F2002/3093 , A61F2002/30952 , A61F2002/3096 , A61F2002/30985 , A61F2002/3412 , A61F2002/3429 , A61F2002/3441 , A61F2002/3448 , A61F2002/348 , A61F2002/3487 , A61F2002/4615 , A61F2002/4619 , B33Y80/00 , G06F9/45533
摘要： Systems, devices, and methods are provided for orthopedic implants. The implants may include a base member, such as an acetabular shell or an augment, that is configured to couple with an augment, flange cup, mounting member, or any other suitable orthopedic attachment. Any of the implantable components may be include one or more porous surfaces. The porous surface may be textured by protrusions that connect to and extend from the surface. The sizes and concentration of the protrusions may be varied for specific applications to accommodate different implants and patient anatomies. A porous implant may also include one or more internal or external solid portions that strengthen the implant.
摘要翻译：为矫形植入物提供系统，装置和方法。植入物可以包括基部构件，例如髋臼壳或增大件，其构造成与增大件，凸缘杯，安装构件或任何其他合适的矫形附件相连接。任何可植入部件可以包括一个或多个多孔表面。多孔表面可以通过连接到表面并从表面延伸的突起来纹理化。突出物的尺寸和浓度可以针对特定应用而变化以适应不同的植入物和患者解剖结构。多孔植入物还可以包括强化植入物的一个或多个内部或外部固体部分。

27. 发明申请

WO2011156512A3 IMPLANT COMPONENTS AND METHODS 审中-公开
标题翻译：植入组件和方法
公开(公告)号：WO2011156512A3
公开(公告)日：2012-04-05
申请号：PCT/US2011039660
申请日：2011-06-08
申请人： SMITH & NEPHEW INC , QUINN NATHANIEL , SHEA JEFFREY JOEL
发明人： QUINN NATHANIEL , SHEA JEFFREY JOEL
IPC分类号： A61F2/46 , A61B17/68 , A61B17/76 , A61F2/30 , A61F2/34
CPC分类号： A61F2/34 , A61B17/8066 , A61B17/82 , A61B17/866 , A61B17/8685 , A61F2/30734 , A61F2/30749 , A61F2/30771 , A61F2/30907 , A61F2/30942 , A61F2/30965 , A61F2/4609 , A61F2002/30011 , A61F2002/30013 , A61F2002/30169 , A61F2002/30189 , A61F2002/30326 , A61F2002/3038 , A61F2002/30387 , A61F2002/30449 , A61F2002/30462 , A61F2002/30471 , A61F2002/30474 , A61F2002/30507 , A61F2002/30538 , A61F2002/30578 , A61F2002/30579 , A61F2002/30604 , A61F2002/30611 , A61F2002/30617 , A61F2002/30736 , A61F2002/3082 , A61F2002/30841 , A61F2002/30891 , A61F2002/3092 , A61F2002/3093 , A61F2002/30952 , A61F2002/3096 , A61F2002/30985 , A61F2002/3412 , A61F2002/3429 , A61F2002/3441 , A61F2002/3448 , A61F2002/348 , A61F2002/3487 , A61F2002/4615 , A61F2002/4619 , B33Y80/00 , G06F9/45533
摘要： Systems, devices, and methods are provided for orthopedic implants. The implants may include a base member, such as an acetabular shell or an augment, that is configured to couple with an augment, flange cup, mounting member, or any other suitable orthopedic attachment. An implant may include a base member that has at least two projections with a gap between the projections. The gap between the projections allows the implant to be implanted around another implanted component, such as around a bone screw of an acetabular shell. The implant may include a fixation element, such as a screw or a cement trough, on one or more projections to couple the implant to an implanted acetabular shell. The implant may also include timing marks to facilitate alignment with corresponding marks on another implanted component.
摘要翻译：为矫形植入物提供系统，装置和方法。植入物可以包括基部构件，例如髋臼壳或增大件，其构造成与增大件，凸缘杯，安装构件或任何其他合适的矫形附件相连接。植入物可以包括具有在突起之间具有间隙的至少两个突起的基底构件。突起之间的间隙允许将植入物植入在另一植入部件周围，例如围绕髋臼壳的骨螺钉。植入物可以包括在一个或多个突起上的固定元件，例如螺钉或水泥槽，以将植入物联接到植入的髋臼壳上。植入物还可以包括定时标记，以便于与另一植入部件上的对应标记对准。

28. 发明申请

WO2011156510A2 IMPLANT COMPONENTS AND METHODS 审中-公开
标题翻译：植入组件和方法
公开(公告)号：WO2011156510A2
公开(公告)日：2011-12-15
申请号：PCT/US2011/039658
申请日：2011-06-08
申请人： SMITH & NEPHEW, INC. , CONWAY, Justin, Steve , LANDON, Ryan, L. , SHEA, Jeffrey, Joel
发明人： CONWAY, Justin, Steve , LANDON, Ryan, L. , SHEA, Jeffrey, Joel
IPC分类号： A61F2/30 , A61L27/56 , A61L27/14 , B29C44/12
CPC分类号： A61F2/34 , A61B17/8066 , A61B17/82 , A61B17/866 , A61B17/8685 , A61F2/30734 , A61F2/30749 , A61F2/30771 , A61F2/30907 , A61F2/30942 , A61F2/30965 , A61F2/4609 , A61F2002/30011 , A61F2002/30013 , A61F2002/30169 , A61F2002/30189 , A61F2002/30326 , A61F2002/3038 , A61F2002/30387 , A61F2002/30449 , A61F2002/30462 , A61F2002/30471 , A61F2002/30474 , A61F2002/30507 , A61F2002/30538 , A61F2002/30578 , A61F2002/30579 , A61F2002/30604 , A61F2002/30611 , A61F2002/30617 , A61F2002/30736 , A61F2002/3082 , A61F2002/30841 , A61F2002/30891 , A61F2002/3092 , A61F2002/3093 , A61F2002/30952 , A61F2002/3096 , A61F2002/30985 , A61F2002/3412 , A61F2002/3429 , A61F2002/3441 , A61F2002/3448 , A61F2002/348 , A61F2002/3487 , A61F2002/4615 , A61F2002/4619 , B33Y80/00 , G06F9/45533
摘要： Systems, devices, and methods are provided for orthopedic implants. The implants may include a base member, such as an acetabular shell or an augment, that is configured to couple with an augment, flange cup, mounting member, or any other suitable orthopedic attachment. Any of the implantable components may be include one or more porous surfaces. The porous surface may be textured by protrusions that connect to and extend from the surface. The sizes and concentration of the protrusions may be varied for specific applications to accommodate different implants and patient anatomies. A porous implant may also include one or more internal or external solid portions that strengthen the implant.
摘要翻译：为矫形植入物提供系统，装置和方法。植入物可以包括基部构件，例如髋臼壳或增大件，其构造成与增大件，凸缘杯，安装构件或任何其他合适的矫形附件相连接。任何可植入部件可以包括一个或多个多孔表面。多孔表面可以通过连接到表面并从表面延伸的突起来纹理化。突出物的尺寸和浓度可以针对特定应用而变化以适应不同的植入物和患者解剖结构。多孔植入物还可以包括强化植入物的一个或多个内部或外部固体部分。

29. 发明申请

WO2011138646A1 INTEGRATED PROSTHETIC ELEMENT 审中-公开
标题翻译：综合优势元素
公开(公告)号：WO2011138646A1
公开(公告)日：2011-11-10
申请号：PCT/IB2011/000407
申请日：2011-02-25
申请人： LIMACORPORATE SPA , PRESSACCO, Michele
发明人： PRESSACCO, Michele
IPC分类号： A61F2/30
CPC分类号： A61F2/30 , A61F2/3094 , A61F2002/30065 , A61F2002/30772 , A61F2002/3092 , A61F2002/30971 , A61F2002/30985 , A61F2210/0071 , A61F2310/00023 , A61F2310/00029 , A61F2310/00131 , B33Y80/00
摘要： Integrated prosthetic element usable for bone implant operations or as a bone filler or replacement, comprising at least a metal support (30) and an insert (13) made of plastic material coupled with at least a first surface of said metal support (30) so as to define a wear surface, or insert, of adjustable thickness. The metal support (30) comprises, on the side opposite said first surface, a second surface intended to be coupled with the bone part on which the prosthesis or bone replacement is installed. The first surface comprises a layer (1 1) having cavities or holes (12) distributed in a substantially uniform manner and suitable for anchorage and solidarization of the plastic material that makes up the insert (13), while said second surface comprises a porous layer (16) suitable to optimize the bone anchorage. The first surface and the second surface are separated by a compact layer (14) that stops the plastic material in the step of forming the plastic insert (13). The cavities or holes (12) of the first surface have bigger shapes and sizes than, and in any case different from, the pores of the second surface.
摘要翻译：可用于骨植入操作或作为骨填料或替代物的集成假体元件，包括至少金属支撑件（30）和由与所述金属支撑件（30）的至少第一表面耦合的塑料材料制成的插入件（13），因此以限定可调节厚度的磨损表面或插入物。金属支撑件（30）在与所述第一表面相对的一侧包括旨在与其上安装有假体或骨置换物的骨部分联接的第二表面。第一表面包括具有以基本上均匀的方式分布并且适合于构成插入件（13）的塑料材料的固定和固化的空腔或孔（12）的层（11），而所述第二表面包括多孔层（16）适合于优化骨锚固。第一表面和第二表面由在形成塑料插入件（13）的步骤中使塑料材料停止的致密层（14）分开。第一表面的空腔或孔（12）具有比第二表面的孔更大的形状和尺寸，并且在任何情况下不同于孔的孔。

30. 发明申请

WO2011082152A1 INTERGRATED MULTI-MATERIAL IMPLANTS AND METHODS OF MANUFACTURE 审中-公开
标题翻译：嵌入式多材料植入物及其制造方法
公开(公告)号：WO2011082152A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/062198
申请日：2010-12-28
申请人： SYNTHES USA, LLC , SYNTHES GMBH , LECHMANN, Beat , SCHMIDLI, Dieter , FRIGG, Robert , NARDINI, Reto
发明人： LECHMANN, Beat , SCHMIDLI, Dieter , FRIGG, Robert , NARDINI, Reto
IPC分类号： A61F2/28 , A61F2/30 , B29C67/00
CPC分类号： B29C64/153 , A61B17/7208 , A61B17/8085 , A61B2017/00526 , A61F2/28 , A61F2/3094 , A61F2/442 , A61F2002/30014 , A61F2002/30075 , A61F2002/30563 , A61F2002/30841 , A61F2002/30971 , A61F2002/30985 , A61F2002/444 , A61F2210/0076 , A61F2210/0085 , A61F2240/001 , B22F3/1055 , B22F2003/1056 , B22F2003/1057 , B22F2003/1058 , B22F2003/1059 , B28B1/001 , B29C64/141 , B29C64/165 , B29L2031/7532 , B33Y10/00 , B33Y30/00 , B33Y70/00
摘要： Provided are methods and systems for fabricating multimaterial bodies in a layer-wise fashion, which bodies may be used bone-stabilizing implants. The multimaterial bodies include rigid and flexible portions that are integrally formed with one another. The multimaterial bodies may be softened or stiffened in specific areas to match the biological or anatomical features of a bone.
摘要翻译：提供了以层次方式制造多材料体的方法和系统，其可以使用骨稳定植入物。多材料体包括彼此一体形成的刚性和柔性部分。多材料体可以在特定区域软化或硬化以匹配骨的生物学或解剖学特征。

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