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21. 发明申请

WO2016106549A1 DISTRIBUTED SEQUENTIAL PATTERN MINING (SPM) USING STATIC TASK DISTRIBUTION STRATEGY 审中-公开
标题翻译：使用静态任务分配策略的分布式顺序模式挖掘（SPM）
公开(公告)号：WO2016106549A1
公开(公告)日：2016-07-07
申请号：PCT/CN2014/095531
申请日：2014-12-30
申请人： TERADATA US, INC. , ZHANG, Qian
发明人： ZHANG, Qian , LI, Tao , ZHAO, Lijun , WANG, Yu , WU, Wenjie , LI, Shaoming
IPC分类号： G06F17/30
CPC分类号： G06F17/30539 , G06F17/30 , G06F17/30474 , G06F2216/03
摘要： Seed patterns are derived from a sequence database. Execution costs for types of seed patterns are computed. Each seed pattern is iteratively distributed to distributed nodes along with that seed pattern's assigned execution cost. The distributed nodes processing in parallel to mine the sequence database for super patterns found in the sequence database. When a distributed node exhausts its execution budget, any remaining mining needed for the seed pattern being mined is reallocated to another distributed node having remaining execution budget.
摘要翻译：种子模式从序列数据库派生。计算种子模式类型的执行成本。每个种子模式与该种子模式的分配的执行成本一起被迭代地分布到分布式节点。分布式节点并行处理序列数据库中发现的超级模式的序列数据库。当分布式节点耗尽其执行预算时，将要开采的种子模式所需的任何剩余采矿重新分配给具有剩余执行预算的另一个分布式节点。

22. 发明申请

WO2015123225A1 AGGREGATING MEMORY TO CREATE A NETWORK ADDRESSIBLE STORAGE VOLUME FOR STORING VIRTUAL MACHINE FILES 审中-公开
标题翻译：聚合存储器创建存储虚拟机文件的网络可访问存储量
公开(公告)号：WO2015123225A1
公开(公告)日：2015-08-20
申请号：PCT/US2015/015285
申请日：2015-02-10
申请人： ATLANTIS COMPUTING, INC. , VENKATESH, Chetan , LU, Jin , ZHANG, Qian , ZHANG, Pu Paul
发明人： VENKATESH, Chetan , LU, Jin , ZHANG, Qian , ZHANG, Pu Paul
IPC分类号： G06F12/16
CPC分类号： G06F3/0644 , G06F3/0604 , G06F3/0664 , G06F3/067 , G06F9/45558 , G06F11/1666 , G06F2009/45583 , G06F2201/815
摘要： A method and apparatus for utilizing virtual machines to pool memory from disparate server systems that may have disparate types of memory is described. The method may include establishing communication between a pool virtual machine and two or more publisher virtual machines. The method may also include aggregating, by the pool virtual machine, portions of memory from each of two or more publisher servers to generate a pool of memory, and providing an application with access to the pool of memory, through the pool virtual machine.
摘要翻译：描述了一种用于利用虚拟机从可能具有不同类型的存储器的不同服务器系统中池存储器的方法和装置。该方法可以包括建立池虚拟机与两个或多个发布者虚拟机之间的通信。该方法还可以包括由池虚拟机从两个或多个发布者服务器中的每一个聚合存储器的一部分，以生成存储池，并通过池虚拟机向应用程序提供对存储池的访问。

23. 发明申请

WO2015047477A3 SYSTEMS AND METHODS FOR THE SYNTHESIS OF HIGH THERMOELECTRIC PERFORMANCE DOPED-SnTe MATERIALS 审中-公开
标题翻译：合成高热电性能掺杂SnTe材料的系统与方法
公开(公告)号：WO2015047477A3
公开(公告)日：2015-06-18
申请号：PCT/US2014042765
申请日：2014-06-17
申请人： UNIV HOUSTON SYSTEM , MASSACHUSETTS INST TECHNOLOGY , REN ZHIFENG , ZHANG QIAN , CHEN GANG
发明人： REN ZHIFENG , ZHANG QIAN , CHEN GANG
IPC分类号： C04B35/00
CPC分类号： H01L35/16 , H01L35/34
摘要： A thermoelectric composition comprising tin (Sn), tellurium (Te) and at least one dopant that comprises a peak dimensionless figure of merit (ZT) of 1.1 and a Seebeck coefficient of at least 50 µV/K and a method of manufacturing the thermoelectric composition. A plurality of components are disposed in a ball-milling vessel, wherein the plurality of components comprise tin (Sn), tellurium (Te), and at least one dopant such as indium (In). The components are subsequently mechanically and thermally processed, for example, by hot-pressing. In response to the mechanical-thermally processing, a thermoelectric composition is formed, wherein the thermoelectric composition comprises a dimensionless figure of merit (ZT) of the thermoelectric composition is at least 0.8, and wherein a Seebeck coefficient of the thermoelectric composition is at least 50 µV/K at any temperature.
摘要翻译：一种包含锡（Sn），碲（Te）和至少一种掺杂剂的热电组合物，其包含峰值无量纲品质因数（ZT）为1.1，塞贝克系数为至少50μV/ K，以及制造热电组合物的方法。多个部件设置在球磨容器中，其中多个部件包括锡（Sn），碲（Te）和至少一种掺杂剂如铟（In）。随后机械和热处理组件，例如通过热压。响应于机械热处理，形成热电组合物，其中热电组合物包含热电组合物的无量纲优点（ZT）至少为0.8，并且其中热电组成的塞贝克系数为至少50 μV/ K。

24. 发明申请

WO2014082279A1 METHOD AND APPARATUS FOR ESTIMATING VIDEO QUALITY 审中-公开
标题翻译：估计视频质量的方法和装置
公开(公告)号：WO2014082279A1
公开(公告)日：2014-06-05
申请号：PCT/CN2012/085618
申请日：2012-11-30
申请人： THOMSON LICENSING , ZHANG, Qian , LIAO, Ning , ZHANG, Fan , CHEN, Zhibo
发明人： ZHANG, Qian , LIAO, Ning , ZHANG, Fan , CHEN, Zhibo
IPC分类号： H04N7/64
CPC分类号： H04N21/44008 , H04N21/23418 , H04N21/44209 , H04N21/4425 , H04N21/6125 , H04N21/64322 , H04N21/6473 , H04N21/64738 , H04N21/64769
摘要： A method and apparatus are disclosed for predicting subjective quality of a video contained in a bit stream on a packet layer. Header information of the bit - stream is parsed and frame layer information, such as frame type, is estimated. Visible artifact levels are then estimated based on frame layer information. An overall artifact level and quality metric are estimated based on artifact levels for individual frames with other parameters. Specifically, different weighting factors are used for different frame types when estimating the levels of initial visible artifacts and propagated visible artifacts. The number of slices per frame is used as a parameter when estimating the overall artifact level for the video. Moreover, the quality assessment model considers quality loss caused by both coding and channel artifacts.
摘要翻译：公开了一种用于预测分组层中的比特流中包含的视频的主观质量的方法和装置。解析比特流的报头信息，并估计帧类型信息，如帧类型。然后基于帧层信息来估计可见的伪像级别。基于具有其他参数的单个帧的伪像级别来估计整体神器级别和质量度量。具体来说，当估计初始可见伪像和传播的可见伪像的水平时，不同的加权因子被用于不同的帧类型。当估计视频的整体神器级别时，每帧的片数被用作参数。此外，质量评估模型考虑了由编码和通道伪影引起的质量损失。

25. 发明申请

WO2012078815A1 SUSTAINED RELEASE IMPLANTS CONTAINING A BIODEGRADABLE POLYMER, CYCLODEXTRIN AND POORLY WATER SOLUBLE ACTIVE COMPOUNDS 审中-公开
标题翻译：含有可生物降解聚合物，环糊精和不溶于水的活性化合物的可持续释放植入物
公开(公告)号：WO2012078815A1
公开(公告)日：2012-06-14
申请号：PCT/US2011/063840
申请日：2011-12-07
申请人： ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC , SCHACHTER, Deborah, M. , ZHANG, Qian , VAN REMOORTERE, Peter , LI, Yufu
发明人： SCHACHTER, Deborah, M. , ZHANG, Qian , VAN REMOORTERE, Peter , LI, Yufu
IPC分类号： A61K9/16 , A61K9/00 , A61K47/48
CPC分类号： A61K9/0024 , A61K9/1647 , A61K47/6951 , B82Y5/00 , Y02A50/411
摘要： We have disclosed an implantable sustained release composition comprising, a biocompatible, biodegradable polymer, a cyclodextrin inclusion complex of a poorly water soluble pharmaceutical agent present, and a plasticizer, where the polymer is the minority phase of the formulation. Furthermore, we disclose an implantable sustained release composition that provides a detectable plasma level of an otherwise poorly soluble drug for at least 28 days.
摘要翻译：我们已经公开了一种植入式缓释组合物，其包含生物相容性生物可降解聚合物，存在的水溶性差的药物的环糊精包合物和增塑剂，其中所述聚合物是制剂的少数阶段。此外，我们公开了一种植入式持续释放组合物，其提供可检测的血浆水平的其他难溶性药物至少28天。

26. 发明申请

WO2011020012A1 LACK OF EXPRESSION OF TNFA AND TYPE 1 RECEPTOR FOR TNFA PROTECTS CANCER CELLS FROM TNFA-INDUCED PROGRAMMED CELL DEATH (CELL APOPTOSIS) 审中-公开
标题翻译：缺乏TNFA和1型受体的TNFA表达保护来自TNFA诱导的编程性细胞死亡（细胞病毒）的癌细胞
公开(公告)号：WO2011020012A1
公开(公告)日：2011-02-17
申请号：PCT/US2010/045462
申请日：2010-08-13
申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , WASIK, Mariusz, A. , ZHANG, Qian , WANG, Hong, Yi
发明人： WASIK, Mariusz, A. , ZHANG, Qian , WANG, Hong, Yi
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827 , C12Q1/6886
摘要： The present invention includes compositions and methods for determining whether a subject is a candidate for TNFα treatment. The invention includes assessing the methylation status of the TNFα promoter and expression of type 1 TNFα receptor (TNF-Rl) in a cell from the subject. Hypermethylation of the TNFα promoter and/or expression of TNF-Rl is an indication that the subject is suffering from cancer and is capable of responding to TNFα treatment accomplished by induction of expression of endogeneous TNFα and/or administration of exogeneous TNFα.
摘要翻译：本发明包括用于确定受试者是否是TNFα治疗候选者的组合物和方法。本发明包括在受试者的细胞中评估TNFα启动子的甲基化状态和1型TNFα受体（TNF-R1）的表达。 TNFa启动子的高甲基化和/或TNF-R1的表达是受试者患有癌症并且能够对通过诱导内源性TNFa的表达和/或外源性TNFα的施用而完成的TNFα治疗的反应的指示。

27. 发明申请

WO2009054996A9 SYSTEMS AND METHODS FOR VIRAL THERAPY 审中-公开
标题翻译：用于病毒治疗的系统和方法
公开(公告)号：WO2009054996A9
公开(公告)日：2009-08-06
申请号：PCT/US2008012061
申请日：2008-10-24
申请人： GENELUX CORP , SZALAY ALADAR A , YU YONG A , CHEN NANHAI , ZHANG QIAN , FRENTZEN ALEXA
发明人： YU YONG A , CHEN NANHAI , ZHANG QIAN , FRENTZEN ALEXA
IPC分类号： G01N33/50 , A61K48/00 , C12N7/00 , C12Q1/70
CPC分类号： G01N33/5011 , A61K35/768 , A61K38/45 , C07K14/005 , C12N7/00 , C12N2710/24122 , C12N2710/24132 , C12N2710/24161 , A61K2300/00
摘要： Diagnostic methods and compositions associated with viral therapy are provided. In particular, methods, compositions, and kits to measure markers and therapeutic indicator predictive of viral efficacy in antitumor therapy are provided. Therapeutic viruses and combinations and kits for use in the practicing the methods also are provided.
摘要翻译：提供了与病毒治疗相关的诊断方法和组合物。具体而言，提供了测量抗肿瘤治疗中的病毒效力预测标记和治疗指标的方法，组合物和试剂盒。还提供了用于实践该方法的治疗性病毒和组合以及试剂盒。

28. 发明申请

WO2009054996A3 SYSTEMS AND METHODS FOR VIRAL THERAPY 审中-公开
标题翻译：用于病毒治疗的系统和方法
公开(公告)号：WO2009054996A3
公开(公告)日：2009-06-11
申请号：PCT/US2008012061
申请日：2008-10-24
申请人： GENELUX CORP , SZALAY ALADAR A , YU YONG A , CHEN NANHAI , ZHANG QIAN , FRENTZEN ALEXA
发明人： YU YONG A , CHEN NANHAI , ZHANG QIAN , FRENTZEN ALEXA
IPC分类号： G01N33/50 , A61K48/00 , C12N7/00 , C12Q1/70
CPC分类号： G01N33/5011 , A61K35/768 , A61K38/45 , C07K14/005 , C12N7/00 , C12N2710/24122 , C12N2710/24132 , C12N2710/24161 , A61K2300/00
摘要： Diagnostic methods and compositions associated with viral therapy are provided. In particular, methods, compositions, and kits to measure markers and therapeutic indicator predictive of viral efficacy in antitumor therapy are provided. Therapeutic viruses and combinations and kits for use in the practicing the methods also are provided.
摘要翻译：提供与病毒治疗相关的诊断方法和组合。特别地，提供了用于测量标志物的方法，组合物和试剂盒以及预防抗肿瘤治疗中的病毒功效的治疗指示剂。还提供了用于实施该方法的治疗病毒和组合和试剂盒。

29. 发明申请

WO2009054996A2 SYSTEMS AND METHODS FOR VIRAL THERAPY 审中-公开
标题翻译：用于病毒治疗的系统和方法
公开(公告)号：WO2009054996A2
公开(公告)日：2009-04-30
申请号：PCT/US2008/012061
申请日：2008-10-24
申请人： GENELUX CORPORATION , SZALAY, Aladar, A. , YU, Yong, A. , CHEN, Nanhai , ZHANG, Qian , FRENTZEN, Alexa
发明人： YU, Yong, A. , CHEN, Nanhai , ZHANG, Qian , FRENTZEN, Alexa
IPC分类号： G01N33/50 , A61K48/00 , C12N7/00 , C12Q1/70
CPC分类号： G01N33/5011 , A61K35/768 , A61K38/45 , C07K14/005 , C12N7/00 , C12N2710/24122 , C12N2710/24132 , C12N2710/24161 , A61K2300/00
摘要： Diagnostic methods and compositions associated with viral therapy are provided. In particular, methods, compositions, and kits to measure markers and therapeutic indicator predictive of viral efficacy in antitumor therapy are provided. Therapeutic viruses and combinations and kits for use in the practicing the methods also are provided.
摘要翻译：提供了与病毒治疗相关的诊断方法和组合物。具体而言，提供了测量抗肿瘤治疗中的病毒效力预测标记和治疗指标的方法，组合物和试剂盒。还提供了用于实践该方法的治疗性病毒和组合以及试剂盒。

30. 发明申请

WO2008156655A3 VACCINIA VIRUS VECTORS ENCODING A SODIUM-DEPENDENT TRANSPORTER PROTEIN FOR IMAGING AND/OR TREATMENT OF TUMORS 审中-公开
公开(公告)号：WO2008156655A3
公开(公告)日：2008-12-24
申请号：PCT/US2008/007377
申请日：2008-06-13
申请人： GENELUX CORPORATION , SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH , FONG, Yuman , CHEN, Nanhai , ZHANG, Qian , YU, Yong, A. , SZALAY, Aladar, A.
发明人： FONG, Yuman , CHEN, Nanhai , ZHANG, Qian , YU, Yong, A. , SZALAY, Aladar, A.
IPC分类号： C12N15/863
摘要： Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in diagnostic methods, such detection and imaging of tumors. The viruses also can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.

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