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21. 发明申请

WO2007102932A2 ENHANCED FILL-FACTOR NMR COILS AND ASSOCIATED METHODS 审中-公开
标题翻译：增强填充因子NMR线圈及相关方法
公开(公告)号：WO2007102932A2
公开(公告)日：2007-09-13
申请号：PCT/US2007/000243
申请日：2007-01-04
申请人： UNIVERSITY OF UTAH RESEARCH FOUNDATION , STEPHENSON, James C. , GALE, Bruce K. , FURSE, Cynthia
发明人： STEPHENSON, James C. , GALE, Bruce K. , FURSE, Cynthia
IPC分类号： G01R33/46
CPC分类号： G01R33/34046 , G01R33/34007 , G01R33/34053 , G01R33/34092
摘要： An NMR probe which includes a probe matrix (24) having a void sample (28) volume therein. A conductive coil (16, 26) can be at least partially embedded in the probe matrix (24). By embedding the conductive coil (16, 26) in the probe matrix (24), the fill-factor can be significantly increased. NMR probes can be formed by a method which includes wrapping a conductive wire (16) around a coil form (18) to produce a coil precursor assembly. The probe matrix (24) can be formed around the conductive wire and coil form with a matrix material using any suitable technique such as soft lithography and/or molding. The coil form can be removed from the probe matrix leaving a void sample volume (28) in the probe matrix. Advantageously, the NMR probes of the present invention allow for fill-factors approaching and achieving 100%.
摘要翻译： NMR探针，其包括其中具有空隙样品（28）体积的探针基质（24）。导电线圈（16,26）可以至少部分地嵌入在探针基体（24）中。通过将导电线圈（16,26）嵌入探针基体（24）中，填充因子可以显着增加。 NMR探针可以通过包括围绕线圈形式（18）缠绕导线（16）以产生线圈前体组件的方法形成。探针矩阵（24）可以使用诸如软光刻和/或模制之类的任何合适的技术在基体材料周围形成导电线和线圈形式。可以从探针基质中除去线圈形式，留下探针基质中的空隙样品体积（28）。有利地，本发明的NMR探针允许填充因子接近并达到100％。

22. 发明申请

WO2007100356A2 A MICROFLUIDIC INTERFACE FOR HIGHLY PARALLEL ADDRESSING OF SENSING ARRAYS 审中-公开
标题翻译：用于感测阵列高度并行寻址的微流体接口
公开(公告)号：WO2007100356A2
公开(公告)日：2007-09-07
申请号：PCT/US2006/038505
申请日：2006-10-02
申请人： UNIVERSITY OF UTAH RESEARCH FOUNDATION , GALE, Bruce, K. , MYSZKA, David , CHANG-YEN, David, A. , NATARAJAN, Sriram , ECKMAN, Josh
发明人： GALE, Bruce, K. , MYSZKA, David , CHANG-YEN, David, A. , NATARAJAN, Sriram , ECKMAN, Josh
CPC分类号： G01N33/553 , B01J19/0046 , B01L3/0293 , B01L3/5025 , B01L3/502715 , B01L3/50273 , B01L2200/021 , B01L2300/0636 , B01L2300/0819 , B01L2300/0822 , B01L2300/0877 , B01L2400/0487 , C12N15/1093 , G01N35/1074 , G01N2035/00158 , G01N2035/1039 , Y10T436/2575
摘要： Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein, cells, or other substances on a microarray slide, wafer, or other surface. It may also be used to perform various chemistry steps on the same spots. The spotter increases the surface density of substances at each spot by directing a flow the desired substance (or a solution thereof) over the spot area until surface saturation is accomplished. The spotter may be loaded by well plate handling equipment. The spotter uses wells, microconduits, and orifices to deliver the substances. Each orifice may be connected to two wells via microconduits. When the spotter face contacts a surface, a seal is formed between the orifices in the spotter face and the surface. The same or different substances may be flowed to each orifice and over the surface, thereby forming an array of spots on the surface. Any number of wells, microconduits, and orifices may be incorporated into a spotter.
摘要翻译：公开了一种用于形成微量测定器，生物芯片，生物传感器和细胞培养物的检测器装置和方法。斑点斑块可用于将高浓度的蛋白质，细胞或其他物质的斑点沉积在微阵列载玻片，晶片或其他表面上。它也可以用于在同一点上执行各种化学步骤。点样器通过将所需物质（或其溶液）流过斑点区域直到达到表面饱和为止，增加每个斑点处物质的表面密度。识别器可以由井板处理设备装载。检测员使用井，微管道和孔口来输送物质。每个孔可以通过微管连接到两个孔。当检查器面接触表面时，在检查器面和表面之间的孔口之间形成密封。相同或不同的物质可以流到每个孔口和表面上，从而在表面上形成点阵列。任何数量的井，微管和孔可以并入到一个点样器中。

23. 发明申请

WO2007016719A1 ADAPTOR, INTERMEDIATE ADAPTOR AND TOOTH ASSEMBLY OR CONSTRUCTION 审中-公开
标题翻译：适配器，中间适配器和牙科装配或结构
公开(公告)号：WO2007016719A1
公开(公告)日：2007-02-15
申请号：PCT/AU2005/001687
申请日：2005-11-02
申请人： CUTTING EDGES REPLACEMENT PARTS PTY LTD , BRINKLEY, Wayne , GUIMARAES, Miguel , LILLEY, Bruce , HIBBERT, Trevor , GALE, Bruce
发明人： BRINKLEY, Wayne , GUIMARAES, Miguel , LILLEY, Bruce , HIBBERT, Trevor , GALE, Bruce
IPC分类号： E02F9/28
CPC分类号： E02F9/2858 , E02F9/2825 , E02F9/2883
摘要： The present invention provides a ground engaging tooth sub-assembly including a first and second component which are adapted to be assembled, said first component having at least one protrusion thereon to be received by said second component, said protrusion acting as a hook means, with said second component including a recess to receive said protrusion when said first and second components are connected, whereby said first and second components can be cantilevered with respect to each other. The present invention further provides a lock member for a ground engaging tooth sub assembly, said lock member including a threaded shaft having two opposed like formations for engaging surfaces of respective apertures in opposed sides of a first member of said sub assembly, wherein rotation of said shaft causes said formations to move towards or away from each other so as to engage said surfaces thereby preventing said first member of said sub assembly being disassembled from a second member. The present invention further provides shroud mounting system for mounting a shroud to an earth engaging implement, said implement being able to receive at least two respective adaptors having shroud mounting formations on respective sides thereof, with at least one mounting formation on a first adaptor being opposed to at least one mounting formation on a second adaptor when said first and second adaptor are adjacent each other when mounted on said implement, said mounting formations engage complementary formations on a shroud, whereby said shroud can be secured to said first and second adaptors. The present invention also provides a method of mounting a shroud to an earth engaging implement, said method comprising the steps of: a) providing at least two adaptors, which can receive ground engaging teeth, said adaptors having mounting lugs which extend towards each other and away from said adaptors, b) providing a shroud which is capable of protecting a forward lip of said implement, and mounting means at each end of said shroud; c) positioning said adaptors on said forward lip of said implement in a spaced apart arrangement whereby they are spaced apart by a distance to allow said shroud to extend from the side of one adaptor to the facing side of the other adaptor; d) positioning said shroud between said adaptors so that said mounting means can engage said lugs; e) locking said mounting means to said lugs, to thereby secure said shroud to said adaptors. The present invention further provides a shroud member adapted to be positioned in a generally vertical plane so as to protect a side lip or edge of a ground engaging implement, said shroud member including a generally longitudinal first bight to receive said lip or edge, and a generally downwardly opening second bight on a base region of said shroud, said second bight being able to receive a locking formation on said implement, said second bight and said locking formation securing said base of said shroud to said implement.
摘要翻译：本发明提供了一种地面接合齿子组件，其包括适于组装的第一和第二部件，所述第一部件具有至少一个突出部，以由所述第二部件容纳，所述突起用作钩装置，所述第二部件包括当所述第一和第二部件连接时接收所述突起的凹部，由此所述第一和第二部件可以相对于彼此悬臂。本发明还提供了一种用于地面接合齿子组件的锁定构件，所述锁定构件包括具有两个相对的相似构造的螺纹轴，用于接合所述子组件的第一构件的相对侧中的相应孔的表面，其中所述轴使所述结构彼此移动或远离，以便与所述表面接合，从而防止所述副组件的所述第一构件与第二构件分离。本发明还提供了一种用于将护罩安装到地面接合工具的护罩安装系统，所述工具能够容纳至少两个相应的适配器，其在相应侧面上具有护罩安装结构，其中至少一个安装结构在第一适配器上相对当安装在所述工具上时，当所述第一和第二适配器彼此相邻时，所述至少一个安装结构在第二适配器上，所述安装结构接合在护罩上的互补结构，由此所述护罩可固定到所述第一和第二适配器。本发明还提供了一种将护罩安装到地面接合工具的方法，所述方法包括以下步骤：a）提供至少两个可接收地面接合齿的适配器，所述适配器具有朝向彼此延伸的安装凸耳，远离所述适配器，b）提供能够保护所述工具的前唇的护罩和在所述护罩的每个端部处的安装装置; c）将所述适配器以间隔布置的方式定位在所述工具的所述前边缘上，由此它们间隔一定距离，以允许所述护罩从一个适配器的侧面延伸到另一适配器的相对侧; d）将所述护罩定位在所述适配器之间，使得所述安装装置可接合所述凸耳; e）将所述安装装置锁定到所述凸耳上，从而将所述护罩固定到所述适配器。本发明还提供了一种护罩构件，其适于被定位在大致竖直的平面中，以便保护地面接合工具的侧唇或边缘，所述护罩构件包括大致纵向的第一弯头以容纳所述唇缘或边缘，通常在所述护罩的基部区域上向下打开第二弯头，所述第二弯头能够在所述工具上容纳锁定结构，所述第二弯曲部和所述锁定结构将所述护罩的所述基部固定到所述工具。

24. 发明申请

WO2006110489A3 RAPID PROTOTYPING OF MICROSTRUCTURES USING A CUTTING PLOTTER 审中-公开
标题翻译：使用切割机快速实现微结构
公开(公告)号：WO2006110489A3
公开(公告)日：2007-01-04
申请号：PCT/US2006012899
申请日：2006-04-07
申请人： UNIV UTAH RES FOUND , BARTHOLOMEUSZ DANIEL A , KANTAK AMEYA , LEE SUNG , SRINIVAS MERUGU , SANT HIMANSHU , BOUTTE RONALD W , GALE BRUCE , THOMAS CHARLES
发明人： BARTHOLOMEUSZ DANIEL A , KANTAK AMEYA , LEE SUNG , SRINIVAS MERUGU , SANT HIMANSHU , BOUTTE RONALD W , GALE BRUCE , THOMAS CHARLES
IPC分类号： B32B37/00
CPC分类号： B32B38/10 , B26D7/10 , B26D7/2628 , B26F1/24 , B26F1/3806 , B26F2001/3893 , B29C64/141 , B81B2201/058 , B81C99/009 , B81C2201/019 , Y10T83/293 , Y10T83/303
摘要： A method for making a microstructure includes: providing a film (100) on a release liner (110); feeding the film through a cutting plotter (10); cutting the film with a knife blade (34) of the cutting plotter to form a microstructure pattern; peeling the microstructure pattern from the release liner; and transferring the microstructure pattern to a substrate (170). The cutting plotter for making microstructures includes a knife head with a knife blade disposed adjacent a feed mechanism (20), a motor (42) and control system coupled to the knife head for selectively moving the knife head in relation to the film, and the control system and the knife head having an addressable positioning resolution less than approximately 10 µm.
摘要翻译：制造微结构的方法包括：在剥离衬垫（110）上提供膜（100）; 通过切割机（10）将胶片进给; 用切割机的刀片（34）切割薄膜以形成微结构图案; 从分离衬片剥离微结构图案; 并将微结构图案转移到基板（170）。用于制造微结构的切割机包括具有邻近进给机构（20）设置的刀片的刀头，马达（42）和耦合到刀头的控制系统，用于相对于薄膜选择性地移动刀头，控制系统和刀头具有小于约10μm的可寻址定位分辨率。

25. 发明申请

WO2005024230A2 ROTARY CENTRIFUGAL AND VISCOUS PUMPS 审中-公开
标题翻译：旋转式离心泵和VISCOUS泵
公开(公告)号：WO2005024230A2
公开(公告)日：2005-03-17
申请号：PCT/US2004/028890
申请日：2004-09-03
申请人： UNIVERSITY OF UTAH RESEARCH FOUNDATION , BLANCHARD, Danny , LIGRANI, Phil , GALE, Bruce
发明人： BLANCHARD, Danny , LIGRANI, Phil , GALE, Bruce
IPC分类号： F04B
CPC分类号： F04D5/001 , F04D1/02 , F04D29/22 , F04D29/426
摘要： A pump device (10a, 10b, 10c) includes means for both transferring rotational momentum to the fluid by viscous forces, and imparting centrifugal forces to the fluid. The pump (10a, 10b) can include a wiper (44) extending partially across at least one rotatable disc surface (48, 48b, 48c) of at least one rotatable disc (52, 52b, 52c). The pump (10c) can include a rotatable shaft (150) with a hollow cavity (154) extending from one end to at least one slot (158) extending radially from the hollow cavity.
摘要翻译：泵装置（10a，10b，10c）包括用于通过粘性力将旋转动量传递到流体并赋予流体的离心力的装置。泵（10a，10b）可以包括部分地跨越至少一个可旋转盘（52,52b，52c）的至少一个可旋转盘表面（48,48b，48c）延伸的擦拭器（44）。泵（10c）可以包括具有从一端延伸到从中空腔径向延伸的至少一个狭槽（158）的中空腔（154）的可旋转轴（150）。

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