专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2018096529A1 METHOD FOR MEDICAL TREATMENT PLANNING AND A SYSTEM THEREOF 审中-公开
公开(公告)号：WO2018096529A1
公开(公告)日：2018-05-31
申请号：PCT/IL2017/051266
申请日：2017-11-20
申请人： HALAHMI, Erez , KALEV-KRONIK, Natalie
发明人： HALAHMI, Erez , KALEV-KRONIK, Natalie
IPC分类号： G06F19/28 , G16H20/10 , G01N33/574
摘要： The present invention relates to a method and a system for planning a medical treatment for a patient comprising determining a treatment profile to be administered to the patient including a plurality of doses of different amounts, wherein the treatment profile has a certain time pattern.

12. 发明申请

WO2018085779A1 METHODS FOR ASSESSING GENETIC VARIANT SCREEN PERFORMANCE 审中-公开
标题翻译：评估遗传变异筛选表现的方法
公开(公告)号：WO2018085779A1
公开(公告)日：2018-05-11
申请号：PCT/US2017/060222
申请日：2017-11-06
申请人： COUNSYL, INC.
发明人： GOULD, Genevieve, M. , WANG, Xin , GRAUMAN, Peter, V. , HOGAN, Gregory, John , ROBERTSON, Alexander, De Jong , MAGUIRE, Jared, Robert , KANG, Hyunseok , HAQUE, Imran, Saeedul , EVANS, Eric, Andrew , HAAS, Kevin, R.
IPC分类号： G06F19/22 , C40B30/02 , G06F17/30 , G06F19/28
CPC分类号： G16B40/00 , G06F16/00 , G16B20/00 , G16B35/00 , G16C20/60
摘要： Described herein are methods of assessing the performance of a genetic variant screen. A summary statistic can be determined to assess the performance of the genetic variant screen. In some embodiments, the summary statistic is determined using synthetic copy number variants. In some embodiments, the summary statistic is determined using a reference sequence having a synthetic variant.
摘要翻译：本文描述了评估遗传变体筛选的表现的方法。可以确定总结统计以评估基因变体筛选的表现。在一些实施例中，使用合成拷贝数变体来确定汇总统计量。在一些实施方案中，使用具有合成变体的参考序列来确定概要统计。

13. 发明申请

WO2018071079A1 METHOD AND SYSTEMS FOR THE INDEXING OF BIOINFORMATICS DATA 审中-公开
标题翻译：用于生物信息学数据索引的方法和系统
公开(公告)号：WO2018071079A1
公开(公告)日：2018-04-19
申请号：PCT/US2017/041585
申请日：2017-07-11
申请人： GENOMSYS SA , BALUCH, Mohamed Khoso
发明人： BALUCH, Mohamed Khoso , ALBERTI, Claudio , ZOIA, Giorgio , RENZI, Daniele
IPC分类号： G06F3/00 , G06F3/048 , G06F9/46 , G06F17/30 , G06F19/00 , G06F19/28
摘要： Method and apparatus for the indexing of genome sequence data produced by genome sequencing machines. The proposed method can be applied both to raw sequence data produced by sequencing machines and to those sequence reads that cannot be mapped on any reference sequence according to specific matching criteria. This invention describes a method to partition and index unaligned sequence reads to enable browsing and efficient selective access.
摘要翻译：用于对由基因组测序机器产生的基因组序列数据进行索引的方法和设备。所提出的方法既可以应用于通过测序机生成的原始序列数据，也可以应用于根据特定匹配标准不能被映射到任何参考序列上的那些序列读取。本发明描述了一种对未对齐的序列读取进行分区和索引以使浏览和高效的选择性访问成为可能的方法。

14. 发明申请

WO2018068830A9 METHOD AND SYSTEM FOR THE TRANSMISSION OF BIOINFORMATICS DATA 审中-公开
公开(公告)号：WO2018068830A9
公开(公告)日：2018-04-19
申请号：PCT/EP2016/074311
申请日：2016-10-11
申请人： GENOMSYS SA
发明人： ZOIA, Giorgio , RENZI, Daniele
IPC分类号： G06F19/28
摘要： Method and system for the transmission of genomic data. The transmission of genomic data is realized by employing the multiplexing of a structured compressed genomic dataset in a stream of genomic data partitioned into randomly accessible access units.

15. 发明申请

WO2018068828A9 METHOD AND SYSTEM FOR STORING AND ACCESSING BIOINFORMATICS DATA 审中-公开
公开(公告)号：WO2018068828A9
公开(公告)日：2018-04-19
申请号：PCT/EP2016/074301
申请日：2016-10-11
申请人： GENOMSYS SA
发明人： RENZI, Daniele , ZOIA, Giorgio
IPC分类号： G06F19/28 , G06F19/22
摘要： Method and system for storing and accessing genomic data. Genomic sequencing data are partitioned into access units of different types based on the predictability of the contained data. Access units are classified in different types and the structuring enables selective access and selective processing of genomic data.

16. 发明申请

WO2018068828A1 METHOD AND SYSTEM FOR STORING AND ACCESSING BIOINFORMATICS DATA 审中-公开
标题翻译：用于存储和访问生物信息学数据的方法和系统
公开(公告)号：WO2018068828A1
公开(公告)日：2018-04-19
申请号：PCT/EP2016/074301
申请日：2016-10-11
申请人： GENOMSYS SA
发明人： RENZI, Daniele , ZOIA, Giorgio
IPC分类号： G06F19/28 , G06F19/22
摘要： Method and system for storing and accessing genomic data. Genomic sequencing data are partitioned into access units of different types based on the predictability of the contained data. Access units are classified in different types and the structuring enables selective access and selective processing of genomic data.
摘要翻译：
用于存储和访问基因组数据的方法和系统。根据所含数据的可预测性将基因组测序数据分为不同类型的访问单元。访问单元分为不同类型，结构化可以选择性访问和选择性处理基因组数据。

17. 发明申请

WO2018057888A1 INTEGRATED SYSTEMS AND METHODS FOR AUTOMATED PROCESSING AND ANALYSIS OF BIOLOGICAL SAMPLES, CLINICAL INFORMATION PROCESSING AND CLINICAL TRIAL MATCHING 审中-公开
标题翻译：用于自动处理和分析生物样本的一体化系统和方法，临床信息处理和临床试验匹配
公开(公告)号：WO2018057888A1
公开(公告)日：2018-03-29
申请号：PCT/US2017/052956
申请日：2017-09-22
申请人： DRIVER, INC.
发明人： MATSUGUCHI, Tetsuya , CAULIN, Aleah, Fox , ST.JOHN, John, Alden , BOLEY, Nathan , SOI, Sameer , NUNLEY, Elizabeth , GUSHUE, Timothy , AHMED, Erin, Caitlin , PAZARENTZOS, Evangelos , POLKINGHORN, William , GIANNIKOPOULOS, Petros
IPC分类号： G06F19/12 , G06F19/24 , G06F19/28 , G06F19/20
CPC分类号： C12N15/1072 , C12Q1/6827 , C12Q1/6874 , C12Q1/6886 , C12Q2600/106 , C12Q2600/156 , G16B20/00 , G16B40/20 , G16B40/30 , G16H20/00 , G16H50/20 , C12Q2537/159 , C12Q2537/16
摘要： The present disclosure provides a method for qualifying a subject for a subset of therapies. The medical history data and biologic data may be received for the subject wherein the biologic data is generated from one or more biological samples of the subject. Then, the medical history data and the biologic data may be computer analyzed to yield a genomic-based medical history analysis for the subject. The genomic-based medical history analysis may be used for the subject to query one or more databases of therapies for the subject, to generate the subset of therapies for which the subject qualifies. The subset of therapies may be provided on a user interface on an electronic device of a user.
摘要翻译：本公开提供了用于对治疗子集进行限定对象的方法。可以从对象接收病史数据和生物数据，其中生物数据是从对象的一个或多个生物样本产生的。然后，可以对病史数据和生物数据进行计算机分析以产生对象的基于基因组的病史分析。基于基因组的病史分析可用于受试者查询受试者的一个或多个治疗数据库，以生成受试者有资格的治疗的子集。治疗的子集可以在用户的电子设备上的用户界面上提供。

18. 发明申请

WO2017220508A1 METHODS FOR PROCESSING NEXT-GENERATION SEQUENCING GENOMIC DATA 审中-公开
标题翻译：用于处理下一代测序基因组数据的方法
公开(公告)号：WO2017220508A1
公开(公告)日：2017-12-28
申请号：PCT/EP2017/064968
申请日：2017-06-19
申请人： SOPHIA GENETICS S.A.
发明人： SONG, Lin , STEIJGER, Tamara , BEHR, Jonas , NOVAK, Adam , HERNANDEZ, David , XU, Zhenyu
IPC分类号： G06F19/28 , G06F19/18 , G06F19/22
CPC分类号： G16B20/20 , G16B20/00 , G16B30/00 , G16B30/10 , G16B50/00
摘要： A genomic data analyzer system detects a set of characteristics that uniquely determine the input next-generation-sequencing (NGS) sample processing and corresponding genomic context for optimizing a genomic analysis workflow in precision medicine applications. Depending on characteristics such as the DNA target enrichment amplicon-based or probe-based assay technology, the sample type or laboratory process characteristics, the NGS sequencing technology and the genomic context, the genomic data analyzer automatically selects and configures a data alignment module and a variant calling module to optimize the sensitivity and the specificity of the detection of genomic mutations of clinical relevance such as SNPs and INDELs in a diversity of pathologies. More characteristics of the sequencing technology, the target enrichment technology, the samples or the genomic context may be identified according to intermediary results of the data alignment module and the variant calling module, and the genomic data analyzer may further adapt accordingly the alignment module and the variant calling module to execute specific genomic data processing methods. The genomic data analyzer system can thus automatically serve a diversity of sourcing laboratories operating with different biological assays and sequencing technologies setups for different pathologies without requiring a dedicated manual configuration of the genomic analysis workflow at each laboratory for each possible personalized medicine genomic analysis request.
摘要翻译：基因组数据分析系统检测一组特征，这些特征唯一地确定输入下一代测序（NGS）样品处理和相应的基因组环境，以优化精密医学应用中的基因组分析工作流程。根据基于DNA靶向富集扩增子或基于探针的测定技术，样品类型或实验室过程特征，NGS测序技术和基因组环境等特征，基因组数据分析仪会自动选择和配置数据对齐模块和变体调用模块来优化检测临床相关性基因组突变的敏感性和特异性，如SNP和INDEL在多种病理学中的应用。根据数据比对模块和变异调用模块的中间结果可以确定测序技术，目标富集技术，样品或基因组背景的更多特征，并且基因组数据分析器可以进一步适配对准模块和变体调用模块执行特定的基因组数据处理方法。因此，基因组数据分析仪系统可以自动地服务于多种采购实验室，其针对不同病理学的不同生物测定和测序技术设置操作，而不需要针对每个可能的个性化医学基因组分析请求在每个实验室处进行基因组分析工作流程的专门手动配置。 / p>

19. 发明申请

WO2017214320A1 BIOINFORMATICS SYSTEMS, APPARATUS, AND METHODS FOR PERFORMING SECONDARY AND/OR TERTIARY PROCESSING 审中-公开
标题翻译：用于进行二次和/或三次加工的生物信息系统，装置和方法
公开(公告)号：WO2017214320A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036424
申请日：2017-06-07
申请人： EDICO GENOME, CORP.
发明人： VAN ROOYEN, Pieter , RUEHLE, Michael , MEHIO, Rami , STONE, Gavin , HAHM, Mark , OJARD, Eric , PTASHEK, Amnon
IPC分类号： G06F19/28
摘要： A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit(CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline. Additionally, a second integrated circuit is also provided, where each second integrated circuit forming a field programmable gate array (FPGA), the FPGA being configured by firmware to arrange a set of hardwired digital logic circuits that are interconnected by a plurality of physical interconnects to perform a second set of genomic processing steps of the sequence analysis pipeline, the set of hardwired digital logic circuits of each FPGA being arranged as a set of processing engines to perform the second set of genomic processing steps. A shared memory is also provided.
摘要翻译：提供了用于对基因序列数据执行生物信息学分析的系统，方法和装置。具体而言，提供了用于执行序列分析流水线的基因组分析平台。基因组学分析平台包括第一集成电路中的一个或多个，其中每个第一集成电路形成响应于一个或多个软件算法的中央处理单元（CPU），该软件算法被配置为指示CPU执行第一组基因组处理序列分析流水线的步骤。此外，还提供了第二集成电路，其中每个第二集成电路形成现场可编程门阵列（FPGA），所述FPGA由固件配置为布置一组硬连线数字逻辑电路，所述一组硬连线数字逻辑电路通过多个物理互连互连到执行序列分析流水线的第二组基因组处理步骤，每个FPGA的该组硬连线数字逻辑电路被布置为一组处理引擎以执行第二组基因组处理步骤。还提供共享内存。

20. 发明申请

WO2017142701A1 DIET QUALITY PHOTO NAVIGATION 审中-公开
标题翻译：饮食质量照片导航
公开(公告)号：WO2017142701A1
公开(公告)日：2017-08-24
申请号：PCT/US2017/015720
申请日：2017-01-31
申请人： KATZ, David L.
发明人： KATZ, David L.
IPC分类号： G06F17/00 , G06F17/30 , G06F19/00 , G06F19/26 , G06F19/28
CPC分类号： G09B19/0092 , G09B29/00
摘要： A method for translating levels of diet quality into photographic representations of dietary pattern. The method includes the steps of (a) using a diet quality measure to identify a plurality of dietary patterns that each represent a level of diet quality for a period of time; (b) assigning a dietary score to each of the plurality of dietary patterns; (c) converting the plurality of dietary patterns into representative dietary patterns; and (d) converting the representative dietary patterns into food photographs. The food photographs depict the photographic representation of the dietary patterns for the period of time. The photographic representations of dietary patterns can be used to establish an individual or household's dietary pattern and can be incorporated into programs to navigate a user from a current dietary pattern to a more optimal dietary pattern.
摘要翻译：
一种将饮食质量水平转化为膳食模式摄影表现的方法。该方法包括以下步骤：（a）使用饮食质量测量来识别多个饮食模式，每个饮食模式代表一段时间的饮食质量水平; （b）将饮食分数分配给多种饮食模式中的每一种; （c）将所述多种饮食模式转换为代表性饮食模式; 和（d）将代表性的饮食模式转换成食物照片。食物照片描述了这段时间饮食模式的摄影表现。饮食模式的摄影表现可以用来建立个人或家庭的饮食模式，并且可以结合到程序中以从当前的饮食模式导航到更优化的饮食模式。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式