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11. 发明申请

WO2015169498A1 TREATMENT PLANNING SYSTEM 审中-公开
标题翻译：治疗计划系统
公开(公告)号：WO2015169498A1
公开(公告)日：2015-11-12
申请号：PCT/EP2015/056108
申请日：2015-03-23
申请人： KONINKLIJKE PHILIPS N.V. , SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： AMTHOR, Thomas Erik , UHLEMANN, Falk , BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KUNG, Cynthia Ming-fu , RAVI, Ananth , KRUECKER, Jochen
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1027 , A61N2005/1041
摘要： The generation of the pattern and for the adaptation to the specific geometry requires a lot of manual work. It is an object of the invention to simplify the workflow for the clinician during treatment planning. This object is achieved by a treatment planning system configured for determining a set of catheter or needle insertion positions to be used during treatment comprising. The treatment planning system comprises an image providing module for providing a medical image from which at least one treatment target structure can be derived. Further the treatment planning system comprises a pattern providing module for providing one or a set of standard patterns for catheter or needle insertion comprising a plurality of catheter or needle insertion positions, wherein the catheter or needle positions relate to treatment positions in the at least one treatment target structure.
摘要翻译：模式的生成和适应特定几何需要大量的人工工作。本发明的一个目的是简化治疗计划期间临床医生的工作流程。该目的通过一种治疗计划系统来实现，所述治疗计划系统被配置用于确定在治疗期间使用的一组导管或针插入位置，包括。治疗计划系统包括用于提供医学图像的图像提供模块，从该图像可以导出至少一个治疗目标结构。此外，治疗计划系统包括模式提供模块，用于提供包括多个导管或针插入位置的导管或针插入的一个或一组标准图案，其中导管或针位置涉及至少一个治疗中的治疗位置目标结构。

12. 发明申请

WO2015086480A1 MAGNETIC RESONANCE COIL ASSEMBLY FOR FIDUCIAL MARKERS 审中-公开
标题翻译： FIDUCAL MARKERS的磁共振线圈组件
公开(公告)号：WO2015086480A1
公开(公告)日：2015-06-18
申请号：PCT/EP2014/076807
申请日：2014-12-08
申请人： KONINKLIJKE PHILIPS N.V.
发明人： UHLEMANN, Falk , KRUEGER, Sascha , WIRTZ, Daniel , WEISS, Steffen
IPC分类号： G01R33/34 , G01R33/341 , G01R33/58
CPC分类号： A61B90/39 , A61B5/055 , A61B2090/3958 , G01R33/285 , G01R33/34007 , G01R33/34069 , G01R33/341 , G01R33/58
摘要： The invention provides for a medical apparatus (100) with a magnetic resonance coil assembly (102, 102') comprising a magnetic resonance antenna with a first antenna portion (108, 108') and a second antenna portion (110, 110') for receiving magnetic resonance location data (1246) from a fiducial marker (118, 300, 400, 500). The magnetic resonance coil assembly further comprises a clamp with a first clamping portion (104, 104') and a second clamping portion (106, 106') operable for being moved between an open and a closed configuration. The first clamping portion comprises the first antenna portion. The second clamping portion comprises the second antenna portion. The first and second clamping portions are operable for securing the fiducial marker within a signal reception volume (111) in the closed configuration. When in the open position, the first and second clamping portions enable the fiducial marker being moved into or out of the signal reception volume.
摘要翻译：本发明提供具有磁共振线圈组件（102,102'）的医疗设备（100），该磁共振线圈组件包括具有第一天线部分（108,108'）和第二天线部分（110,110'）的磁共振天线，用于从基准标记（118,300,400,500）接收磁共振位置数据（1246）。磁共振线圈组件还包括具有第一夹持部分（104,104'）的夹具和可操作以在打开和闭合构型之间移动的第二夹持部分（106,106'）。第一夹持部分包括第一天线部分。第二夹持部分包括第二天线部分。第一和第二夹持部分可操作以将基准标记固定在关闭构造中的信号接收体积（111）内。当处于打开位置时，第一和第二夹紧部分使得基准标记物被移入或移出信号接收体积。

13. 发明申请

WO2015044065A1 ALIGNMENT OF THE COORDINATE SYSTEMS OF EXTERNAL BEAM RADIOTHERAPY AMD MAGNETIC RESONANCE IMAGING SYSTEMS 审中-公开
标题翻译：外部射束放射治疗系统的对准AMD磁共振成像系统
公开(公告)号：WO2015044065A1
公开(公告)日：2015-04-02
申请号：PCT/EP2014/070079
申请日：2014-09-22
申请人： KONINKLIJKE PHILIPS N.V.
发明人： UHLEMANN, Falk , OVERWEG, Johannes Adrianus
IPC分类号： A61N5/10 , A61B5/055
CPC分类号： A61N5/1049 , A61B5/0035 , A61B5/0555 , A61B2576/00 , A61N5/1039 , A61N5/1067 , A61N5/1071 , A61N5/1077 , A61N2005/1054 , A61N2005/1055 , A61N2005/1074 , A61N2005/1087 , A61N2005/1089
摘要： The invention provides for a medical instrument (200, 300, 400, 500, 600, 700) comprising a magnetic resonance imaging system (204) operable for acquiring magnetic resonance data (266) from a subject (236) within an imaging zone (232) and an external beam radiotherapy system (202) operable for irradiating a target zone (238) within the imaging zone. The medical instrument further has a radiation beam generation system (208, 302, 302', 302") operable for generating a radiation beam (242, 304, 304', 304") and a radiation beam detection system (243, 502, 502') operable for acquiring radiation beam detection data (270) descriptive of the radiation beam. Instructions cause a processor (248) controlling the instrument to receive (100) planning data (260) descriptive of a spatially dependent radiation dose and generate (102) external beam radiotherapy control commands (264) using the radiation dose. The instructions causes the processor to repeatedly: control (106) the external beam radiotherapy system to irradiate the target zone using the external beam radiotherapy system control commands; generate (108) the radiation beams using the radiation beam generation system; measure (110) the radiation beam detection data using the radiation beam detection system; acquire (112) the magnetic resonance imaging data using the magnetic resonance imaging system, generate (114) a magnetic resonance image (268) using the magnetic resonance image data, determine (116) a registration (274) of the magnetic resonance image to the radiation beam detection data; calculate (118) a mapping (276) using the registration; and modify the external beam radiotherapy system control commands using the mapping.
摘要翻译：本发明提供一种包括磁共振成像系统（204）的医疗器械（200,300,400,500,600,700），所述磁共振成像系统可操作用于从成像区域内的对象（236）获取磁共振数据（266））和外部束放射治疗系统（202），其可操作用于照射成像区域内的目标区域（238）。医疗器械还具有可操作以产生辐射束（242,304,304'，304“）和辐射束检测系统（243,502,502）的辐射束产生系统（208,302,302'，302”） '）可用于获取描述辐射束的辐射束检测数据（270）。指令使处理器（248）控制仪器接收（100）描述空间依赖的辐射剂量的规划数据（260），并使用辐射剂量产生（102）外部束放射治疗控制命令（264）。指令使处理器重复：使用外部束放射治疗系统控制命令控制（106）外束放射治疗系统照射目标区域; 使用辐射束产生系统产生（108）辐射束; 使用辐射束检测系统测量（110）辐射束检测数据; 使用磁共振成像系统获取（112）磁共振成像数据，使用磁共振图像数据生成（114）磁共振图像（268），确定（116）磁共振图像的配准（274）到辐射束检测数据; 使用注册计算（118）映射（276）; 并使用映射修改外部束放射治疗系统控制命令。

14. 发明申请

WO2018134445A1 ACQUISITION OF FOUR DIMENSIONAL MAGNETIC RESONANCE DATA DURING SUBJECT MOTION 审中-公开
公开(公告)号：WO2018134445A1
公开(公告)日：2018-07-26
申请号：PCT/EP2018/051610
申请日：2018-01-23
申请人： KONINKLIJKE PHILIPS N.V.
发明人： UHLEMANN, Falk , NIELSEN, Tim , WUELBERN, Jan, Hendrik
IPC分类号： G01R33/563 , G01R33/567
CPC分类号： G01R33/56325 , G01R33/5676
摘要： The invention provides for a magnetic resonance imaging system (100, 200) comprising a memory (148) for storing machine executable instructions (150) and pulse sequence commands (152). The pulse sequence commands are configured for acquiring a four dimensional magnetic resonance data set (162) from an imaging region of interest (109). The four dimensional magnetic resonance data set is at least divided into three dimensional data magnetic resonance data sets (400, 402, 404, 406, 408) indexed by a repetitive motion phase of the subject. The three dimensional data magnetic resonance data sets are further at least divided into and indexed by k-space portions (410, 412, 414, 416, 418, 420, 422, 424, 426, 428, 430, 432, 434, 436). The magnetic resonance imaging system further comprises a processor (144) for controlling the magnetic resonance imaging system. Execution of the machine executable instructions causes the processor during a first operational portion (310) to iteratively: receive (300) a motion signal (156) descriptive of the repetitive motion phase; acquire (302) an initial k-space portion using the pulse sequence commands, wherein the initial k-space portion is selected from the k-space portions; store (304) the motion signal and the initial k-space portion in a buffer (158) for each iteration of the first operational portion; at least partially construct (306) a motion phase mapping (160) between the motion signal and the repetitive motion phase; and continue (308) the first operational portion until the motion phase mapping is complete. Execution of the machine executable instructions causes the processor to assign (312) the initial k-space portion for each iteration of the first operational portion in the temporary buffer to the four dimensional magnetic resonance data set using the motion phase mapping. Execution of the machine executable instructions causes the processor during a second operational portion (332) to iteratively: receive (314) the motion signal; determine (316) a predicted next motion phase using the motion signal and the motion phase mapping; select (318) a subsequent k-space portion (154) from the k-space portions of the four dimensional magnetic resonance data set using the predicted next motion phase; acquire (320) the subsequent k-space portion using the pulse sequence commands; rereceive (322) the motion signal; determine (324) a current motion phase using the re-received motion signal and the motion phase mapping; assign (326) the subsequent k-space portion to the four dimensional magnetic resonance data set using the current motion phase; and repeat (328) the second operational portion until the k-space portions for each repetitive motion phase has been assigned.

15. 发明申请

WO2015197335A1 MAGNETIC RESONANCE IMAGING SYSTEM WITH INTEGRATED PHOTON DETECTOR RING 审中-公开
标题翻译：具有集成光电探测器环的磁共振成像系统
公开(公告)号：WO2015197335A1
公开(公告)日：2015-12-30
申请号：PCT/EP2015/062423
申请日：2015-06-03
申请人： KONINKLIJKE PHILIPS N.V.
发明人： LIPS, Oliver , OVERWEG, Johannes Adrianus , UHLEMANN, Falk
IPC分类号： G01R33/48 , G01R33/385
CPC分类号： A61B5/0035 , A61B5/055 , A61B6/037 , A61B6/4417 , G01R33/385 , G01R33/3856 , G01R33/481 , G01T1/1603
摘要： The invention provides for a magnetic resonance imaging gradient coil assembly (110) comprising a cylindrical coil carrier tube (129). The cylindrical coil carrier tube has an inner surface (125) and an outer surface (129). The cylindrical coil carrier tube has a cylindrical axis of symmetry (200). The cylindrical coil carrier tube has a center (203). The cylindrical coil carrier tube has a photon detector ring receptacle (122) recessed into the inner surface of the cylindrical coil carrier tube. The detector ring receptacle is centered about the center. The photon detector ring receptacle comprises side walls(126) formed from the cylindrical carrier tube and a solid back wall (128) formed from the cylindrical carrier tube. The magnetic resonance imaging gradient coil assembly further comprises a set of magnetic resonance imaging gradient coils (208, 210) attached to the cylindrical coil carrier tube.
摘要翻译：本发明提供一种包括圆柱形线圈载体管（129）的磁共振成像梯度线圈组件（110）。圆柱形线圈架管具有内表面（125）和外表面（129）。圆柱形线圈载体管具有圆柱形对称轴（200）。圆柱形线圈架管具有中心（203）。圆柱形线圈载体管具有凹入圆柱形线圈载体管的内表面中的光子检测器环插座（122）。检测器环插座以中心为中心。光子检测器环插座包括由圆柱形载体管形成的侧壁（126）和由圆柱形载体管形成的固体后壁（128）。磁共振成像梯度线圈组件还包括附接到圆柱形线圈载体管的一组磁共振成像梯度线圈（208,210）。

16. 发明申请

WO2014033583A1 INTERVENTIONAL GUIDANCE SYSTEM WITH INTEGRATED TRACKING SETUP 审中-公开
标题翻译：具有集成跟踪设置的传统指导系统
公开(公告)号：WO2014033583A1
公开(公告)日：2014-03-06
申请号：PCT/IB2013/056656
申请日：2013-08-15
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： KRUECKER, Jochen , BHARAT, Shyam , KUNG, Cynthia Ming-fu , HALL, Christopher Stephen , UHLEMANN, Falk
IPC分类号： A61B17/34 , A61B19/00 , A61N5/10
CPC分类号： A61B19/5244 , A61B17/3403 , A61B34/20 , A61B2017/00274 , A61B2017/3411 , A61B2034/2051 , A61B2034/2072 , A61N5/1001 , A61N5/1007 , A61N5/1049 , A61N2005/1012 , A61N2005/1051 , A61N2005/1058
摘要： A system with integrated tracking includes a procedure-specific hardware component (112 or 116) disposed at or near a region of interest. A field generator (114) is configured to generate a field with a field of view covering the region of interest. A mounting device (115) is connected to the field generator and is coupled to the procedure-specific hardware. The field generator is fixedly positioned by the mounting device to permit workflow access to the region of interest without interfering with the field generator and to provide a known position of the field generator relative to the region of interest. A tracking device (110) is configured to be inserted in or near the region of interest to be tracked within the field of view of the field generator to generate tracking data.
摘要翻译：具有集成跟踪的系统包括设置在感兴趣区域处或附近的特定于程序的硬件组件（112或116）。场发生器（114）被配置为产生具有覆盖感兴趣区域的视场的场。安装装置（115）连接到场发生器并且耦合到程序特定的硬件。场发生器通过安装装置固定地定位，以允许工作流程进入感兴趣区域而不干扰场发生器，并提供现场发电机相对于感兴趣区域的已知位置。跟踪装置（110）被配置为插入到场发生器的视野内要跟踪的感兴趣区域中或附近，以产生跟踪数据。

17. 发明申请

WO2014016762A1 COMBINED BRACHYTHERAPY AND ELECTROCHEMOTHERAPY CATHETERS 审中-公开
标题翻译：组合的深孔和电疗导管
公开(公告)号：WO2014016762A1
公开(公告)日：2014-01-30
申请号：PCT/IB2013/056019
申请日：2013-07-23
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： AMTHOR, Thomas Erik , KRUEGER, Sascha , WEISS, Steffen , UHLEMANN, Falk
IPC分类号： A61N5/10 , A61N1/32 , A61N1/05 , A61B18/14 , A61N1/20 , A61B18/00
CPC分类号： A61N5/1007 , A61B18/1492 , A61B34/10 , A61B34/25 , A61B90/37 , A61B2018/00107 , A61B2018/00577 , A61B2018/00613 , A61B2018/00994 , A61B2018/143 , A61B2018/1472 , A61B2090/374 , A61B2090/376 , A61B2090/3762 , A61B2090/378 , A61M39/22 , A61N1/0502 , A61N1/205 , A61N1/327 , A61N5/1002 , A61N5/1027 , A61N2005/1008 , A61N2005/1021 , A61N2005/1024
摘要： A medical device for multiple treatment therapies includes a hollow tube (102) having a first end portion with an electrode (104) disposed at the first end portion and an insulator (108) configured over a length of the tube such that conductive materials of the tube, except for the electrode, are electrically isolated from an exterior surface the tube. A conductive connection (127) is configured to electrically couple to the electrode to provide a voltage thereto. A selectively closeable valve (106) is configured to dispense a medical fluid from the tube.
摘要翻译：用于多重治疗疗法的医疗装置包括具有第一端部的中空管（102），第一端部具有设置在第一端部处的电极（104）和在管的长度上配置的绝缘体（108），使得导电材料除了电极之外，管与管的外表面电隔离。导电连接（127）被配置为电耦合到电极以向其提供电压。选择性关闭阀（106）构造成从管分配医用流体。

18. 发明申请

WO2022175453A1 DATA ACQUISITION FOR DRIVING REAL-TIME WORKFLOWS IN A HOSPITAL ENVIRONMENT 审中-公开
公开(公告)号：WO2022175453A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/054077
申请日：2022-02-18
申请人： KONINKLIJKE PHILIPS N.V.
发明人： UHLEMANN, Falk , AMTHOR, Thomas Erik , SCHMIDT, Joachim Dieter , FINDEKLEE, Christian , WANG, Xinyu , BORGERT, Jörn
IPC分类号： G16H40/20 , G06Q10/06 , G06Q10/10 , G16H40/67
摘要： In order to monitor real-time process and workflows, modular sensors may be deployed and a processing server may receive sensor information from the modular sensors. The processing server may contextualize the received sensor information and generate a real-time process and workflow status based on the contextualized sensor information.

19. 发明申请

WO2014121991A1 ACTIVE COMPENSATION FOR FIELD DISTORTING COMPONENTS IN A MAGNETIC RESONANCE IMAGING SYSTEM WITH A GANTRY 审中-公开
标题翻译：用于GANTRY的磁共振成像系统中的场失真成分的主动补偿
公开(公告)号：WO2014121991A1
公开(公告)日：2014-08-14
申请号：PCT/EP2014/050743
申请日：2014-01-16
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： OVERWEG, Johannes Adrianus , UHLEMANN, Falk
IPC分类号： G01R33/3875 , G01R33/389 , G01R33/48
CPC分类号： G01R33/4808 , A61B5/0555 , A61N5/1039 , A61N2005/1055 , G01R33/307 , G01R33/3875 , G01R33/389 , G01R33/4812 , G01R33/56383 , G01R33/56563
摘要： The invention provides for a medical apparatus (300, 400, 500) comprising: a magnetic resonance imaging system (306); magnetic compensation coils (334, 335) for compensating for magnetic inhomogeneities within the imaging zone; a gantry (308) operable for rotating about the imaging zone; a position sensor (312) for measuring the angular position and the angular velocity of the gantry; at least one magnetic field distorting component (310, 510, 512) in the gantry, a memory (362) storing machine executable instructions (380, 382, 410, 530, 532) and field correction data (372). The instructions cause a processor to: receive (100, 200) the position and angular velocity data from the position sensor; determine (102, 202) coil control commands (374) for controlling the magnetic compensation coils using the field correction data, the position data and the angular velocity data; control (104, 204) the magnetic compensation coils to compensate for magnetic inhomogeneities within the imaging zone using the coil control commands; and acquire (106, 212) the magnetic resonance data.
摘要翻译：本发明提供一种医疗设备（300,400,500），包括：磁共振成像系统（306）; 磁补偿线圈（334,335），用于补偿成像区内的磁不均匀性; 可操作以围绕成像区域旋转的台架（308）用于测量台架的角位置和角速度的位置传感器（312）; 所述台架中的至少一个磁场失真部件（310,510,512），存储机器可执行指令（380,382,410,530,532）和场校正数据（372）的存储器（362）。指令使处理器：从位置传感器接收（100,200）位置和角速度数据; 确定（102,202）线圈控制命令（374），用于使用场校正数据，位置数据和角速度数据来控制磁补偿线圈; 使用线圈控制命令来控制（104,204）磁补偿线圈以补偿成像区内的磁不均匀性; 并获取磁共振数据（106,212）。

20. 发明申请

WO2014026837A1 PATIENT BED WITH MAGNETIC RESONANCE RADIO FREQUENCY ANTENNA, PARTICULARLY FOR USE IN A MAGNETIC RESONANCE IMAGING GUIDED THERAPY SYSTEM 审中-公开
标题翻译：具有磁共振无线电频率天线的患者床，特别用于磁共振成像指导治疗系统
公开(公告)号：WO2014026837A1
公开(公告)日：2014-02-20
申请号：PCT/EP2013/065720
申请日：2013-07-25
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： UHLEMANN, Falk
IPC分类号： G01R33/48 , G01R33/34 , A61B5/055
CPC分类号： A61B5/0555 , A61G7/0755 , A61N2005/1055 , G01R33/30 , G01R33/307 , G01R33/34 , G01R33/34007 , G01R33/34084 , G01R33/4808
摘要： A patient bed, particularly for use in a magnetic resonance (MR) imaging- guided therapy system employing at least one out of ionizing radiation and ultrasound energy for therapy purposes, having an abdominal support portion (14) for supporting an abdominal region (18) of a subject (12) during magnetic resonance-guided therapy, comprising at least one magnetic resonance (MR) radio frequency (RF) antenna device (48) arranged at a top side (26) of the patient bed in a patient bed center region (30), with at least one MR RF antenna (50) that is enclosed in a housing (52) having two side surfaces (54) opposing each other, wherein, in at least one state of operation, each side surface (54) of the MR RF antenna device (48) is provided to be proximal to an inner side of each of the subject's legs (22), and wherein, in the at least one state of operation, the MR RF antenna device (48) is provided to be proximal to a subject's perineum (20); an MR radio frequency (RF) antenna device (48) therefor; and a therapy system employing at least one out of ionizing radiation and ultrasound energy for therapy purposes that is guided by an MR imaging device with a patient bed having at least one MR radio frequency (RF) antenna device (48).
摘要翻译：一种患者床，特别是在用于治疗目的的电离辐射和超声能量中的至少一种的磁共振（MR）成像引导治疗系统中，具有用于支撑腹部区域（18）的腹部支撑部分（14）在磁共振引导治疗期间包括至少一个磁共振（MR）射频（RF）天线装置（48）的受试者（12），所述磁共振（MR）射频（RF）天线装置布置在患者床中心区域中的患者床的顶侧（30），其中至少一个MR RF天线（50）被封装在具有彼此相对的两个侧表面（54）的壳体（52）中，其中在至少一个操作状态下，每个侧表面（54） MR射频天线装置（48）被设置为接近对象腿部（22）的内侧，并且其中，在至少一个操作状态中，设置MR RF天线装置（48）靠近受试者的会阴（20）; 用于其的MR射频（RF）天线装置（48）; 以及由具有至少一个MR射频（RF）天线装置（48）的患者床的MR成像装置引导的用于治疗目的中的至少一个电离辐射和超声能量的治疗系统。

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