专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2010027678A3 MEDICAL DEVICES HAVING INORGANIC COATINGS FOR THERAPEUTIC AGENT DELIVERY 审中-公开
标题翻译：具有无机涂层用于治疗药物递送的医疗装置
公开(公告)号：WO2010027678A3
公开(公告)日：2010-09-23
申请号：PCT/US2009054394
申请日：2009-08-20
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , SCHEUERMANN TORSTEN , O'BRIEN BARRY J , XU YIXIN , FORSYTH BRUCE
发明人： WEBER JAN , SCHEUERMANN TORSTEN , O'BRIEN BARRY J , XU YIXIN , FORSYTH BRUCE
IPC分类号： A61L27/30 , A61L27/54 , A61L27/56 , A61L31/08 , A61L31/14 , A61L31/16
CPC分类号： A61L27/30 , A61L27/54 , A61L27/56 , A61L31/082 , A61L31/146 , A61L31/16 , A61L2300/608
摘要： According to an aspect of the invention, medical devices are provided that comprise a substrate, at least one therapeutic agent disposed over or in the substrate, and at least one inorganic layer disposed over the therapeutic agent and the substrate, wherein the inorganic layer is either a porous inorganic layer or is a non-porous layer that becomes a porous inorganic layer in vivo. Other aspects of the invention comprise methods for forming medical devices.
摘要翻译：根据本发明的一个方面，提供了医疗装置，其包括衬底，设置在衬底上或衬底中的至少一种治疗剂，以及设置在治疗剂和衬底上的至少一个无机层，其中无机层是多孔无机层，或者是在体内成为多孔无机层的无孔层。本发明的其它方面包括用于形成医疗装置的方法。

12. 发明申请

WO2009132176A3 MEDICAL DEVICES HAVING INORGANIC PARTICLE LAYERS 审中-公开
标题翻译：具有无机颗粒层的医疗器械
公开(公告)号：WO2009132176A3
公开(公告)日：2010-09-02
申请号：PCT/US2009041520
申请日：2009-04-23
申请人： BOSTON SCIENT SCIMED INC , KUEHLING MICHAEL , SEIDEL DOMINIQUE , SCHEUERMANN TORSTEN , WEBER JAN
发明人： KUEHLING MICHAEL , SEIDEL DOMINIQUE , SCHEUERMANN TORSTEN , WEBER JAN
IPC分类号： A61L31/08 , A61L31/16
CPC分类号： A61L31/16 , A61L31/08 , A61L2300/61 , A61L2300/62 , A61L2420/02
摘要： An expandable medical device having a particle layer disposed over a reservoir containing a therapeutic agent. The particle layer has a first porosity when the medical device is in the unexpanded configuration and a second porosity when the medical device is in the expanded configuration. The particle layer comprises a plurality of micron-sized or nano-sized particles. In certain embodiments, the particles are not connected to each other, and as such, the different porosities are provided by changes in the spacing between the particles as the medical device is expanded/unexpanded. Also disclosed are medical devices having a particle layer, wherein the particle layer comprises a plurality of encapsulated particles, and methods of coating medical devices with particles.
摘要翻译：一种可膨胀医疗装置，其具有设置在含有治疗剂的贮器上的颗粒层。当医疗装置处于未膨胀构型时，颗粒层具有第一孔隙度，并且当医疗装置处于膨胀构型时具有第二孔隙率。颗粒层包含多个微米级或纳米尺寸的颗粒。在某些实施方案中，颗粒彼此不连接，因此，当医疗装置膨胀/未膨胀时，由颗粒之间的间隔的变化提供不同的孔隙度。还公开了具有颗粒层的医疗装置，其中所述颗粒层包含多个包封的颗粒，以及用颗粒涂覆医疗装置的方法。

13. 发明申请

WO2013013156A3 PERCUTANEOUS DEVICES AND METHODS TO VISUALIZE, TARGET AND ABLATE NERVES 审中-公开
标题翻译： PERCUTANEOUS DEVICES AND METHODS to VISUALIZE，TARGET AND ABLATE NERVES
公开(公告)号：WO2013013156A3
公开(公告)日：2013-03-21
申请号：PCT/US2012047614
申请日：2012-07-20
申请人： BOSTON SCIENT SCIMED INC , SCHEUERMANN TORSTEN , TEO TAT-JIN , HASTINGS ROGER N
发明人： SCHEUERMANN TORSTEN , TEO TAT-JIN , HASTINGS ROGER N
IPC分类号： A61M25/10 , A61B5/00 , A61B5/20 , A61B18/24
CPC分类号： A61B5/04001 , A61B5/0071 , A61B5/0095 , A61B5/01 , A61B5/201 , A61B5/4029 , A61B8/4461 , A61B18/02 , A61B18/1492 , A61B18/24 , A61B18/26 , A61B2018/00023 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00386 , A61B2018/00404 , A61B2018/00494 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2090/3966 , A61N1/403 , A61N7/00 , A61N7/02 , A61N2007/003 , A61N2007/0082 , A61N2007/0091
摘要： Apparatuses for identifying nerve tissue and methods for making and using the same are disclosed. An example apparatus may include an elongate shaft (124) having a distal region (120) configured to be percutaneously deployed within a patient. An active imaging structure (112, 114) may be disposed on the distal region. The active imaging structure may be configured to remotely image nerve tissue by exciting a signal in nerve tissue from a percutaneous location and receiving the signal from a percutaneous location. The active imaging structure may include one or more probes (102).
摘要翻译：公开了用于鉴定神经组织的装置及其制造和使用方法。示例性装置可以包括细长轴（124），其具有构造成经皮部署在患者体内的远端区域（120）。主动成像结构（112,114）可以设置在远侧区域上。活动成像结构可以被配置为通过从经皮位置激发神经组织中的信号并从经皮位置接收信号来远程地图像神经组织。主动成像结构可以包括一个或多个探针（102）。

14. 发明申请

WO2010011515A3 MEDICAL DEVICES HAVING INORGANIC BARRIER COATINGS 审中-公开
标题翻译：具有无机屏障涂层的医疗设备
公开(公告)号：WO2010011515A3
公开(公告)日：2010-11-25
申请号：PCT/US2009050365
申请日：2009-07-13
申请人： BOSTON SCIENT SCIMED INC , SCHEUERMANN TORSTEN , KUEHLING MICHAEL , WEBER JAN , SEIDEL DOMINIQUE
发明人： SCHEUERMANN TORSTEN , KUEHLING MICHAEL , WEBER JAN , SEIDEL DOMINIQUE
IPC分类号： A61L31/14 , A61L31/08 , A61L31/16
CPC分类号： A61L31/16 , A61L31/082 , A61L31/146 , A61L2300/608 , A61L2420/08
摘要： Medical devices having a barrier layer comprising an inorganic material. The medical device has a reservoir containing a therapeutic agent and the barrier layer is disposed over the reservoir. In one aspect, the barrier layer has one permeability to the therapeutic agent at one portion of the medical device and a different permeability at another portion of the medical device. In another aspect, the dosage amount of the therapeutic agent in the reservoir at one portion of the medical device is different from the dosage amount of the therapeutic agent in the reservoir at another portion of the medical device. In another aspect, a bioresorbable layer is disposed over the barrier layer at one or more portions of the medical device, wherein the bioresorbable layer comprises a bioresorbable material. Also, methods of coating a medical device are disclosed, in which a barrier layer over a medical device is formed using a lithographic etching process where a plurality of particles serve as an etch mask.
摘要翻译：具有包含无机材料的阻挡层的医疗装置。医疗装置具有容纳治疗剂的储存器，并且阻挡层设置在储存器上方。在一个方面，阻隔层在医疗装置的一部分具有对治疗剂的一种渗透性，并且在医疗装置的另一部分具有不同的渗透性。在另一方面，医疗装置的一部分处的储器中的治疗剂的剂量与医疗装置的另一部分处的储器中的治疗剂的剂量不同。另一方面，生物可再吸收层在医疗装置的一个或多个部分处设置在阻隔层上，其中生物可吸收层包含生物可吸收材料。而且，公开了涂覆医疗装置的方法，其中使用平版印刷蚀刻工艺形成医疗装置上的阻挡层，其中多个颗粒用作蚀刻掩模。

15. 发明申请

WO2010008969A3 MEDICAL DEVICES HAVING METAL COATINGS FOR CONTROLLED DRUG RELEASE 审中-公开
标题翻译：带有金属涂层的医疗器械用于控制药物释放
公开(公告)号：WO2010008969A3
公开(公告)日：2010-10-14
申请号：PCT/US2009049802
申请日：2009-07-07
申请人： BOSTON SCIENT SCIMED INC , FLANAGAN AIDEN , O'BRIEN BARRY , SCHEUERMANN TORSTEN
发明人： FLANAGAN AIDEN , O'BRIEN BARRY , SCHEUERMANN TORSTEN
IPC分类号： A61L31/08 , A61L31/16
CPC分类号： A61L31/088 , A61L31/16 , A61L2300/604 , A61L2300/624
摘要： Medical devices having a plurality of nanoparticles disposed over a surface of the medical device. The nanoparticles have a core comprising a therapeutic agent and a shell surrounding the core, wherein the shell comprises a metal. A barrier layer is disposed over the nanoparticles. The barrier layer is water-permeable and comprises a metal that may be different from the metal used in the nanoparticle shells. In certain embodiments, the metal in the barrier layer undergoes galvanic corrosion. Also disclosed are medical device having a reservoir containing a therapeutic agent, with nanoparticles and a barrier layer being disposed over the reservoir; and medical devices having multiple barrier layers and multiple reservoirs containing therapeutic agents.
摘要翻译：具有设置在医疗装置的表面上的多个纳米颗粒的医疗装置。纳米粒子具有包含治疗剂和包围核的壳的核心，其中壳包含金属。阻挡层设置在纳米粒子上。阻挡层是水可渗透的并且包含可以不同于纳米颗粒壳中使用的金属的金属。在某些实施例中，阻挡层中的金属经受电化学腐蚀。还公开了具有包含治疗剂的储库的医疗装置，其中纳米颗粒和阻挡层设置在储库上; 以及具有多个阻隔层和含有治疗剂的多个储库的医疗装置。

16. 发明申请

WO2014175996A3 DEVICES FOR OBSTRUCTING PASSAGE OF AIR OR OTHER CONTAMINANTS INTO A PORTION OF A LUNG AND METHODS OF USE 审中-公开
标题翻译：用于阻止空气或其他污染物进入肺部的装置和使用方法
公开(公告)号：WO2014175996A3
公开(公告)日：2014-12-24
申请号：PCT/US2014032222
申请日：2014-03-28
申请人： BOSTON SCIENT SCIMED INC
发明人： WEBER JAN , FLANAGAN AIDEN , SCHEUERMANN TORSTEN
IPC分类号： A61B17/12 , A61B17/00 , A61B19/00 , A61F2/04
CPC分类号： A61F2/04 , A61B5/0816 , A61B17/12036 , A61B17/1204 , A61B17/12104 , A61B17/12168 , A61B17/12177 , A61B2017/00221 , A61B2017/00411 , A61B2017/00699 , A61B2017/00734 , A61B2017/00809 , A61B2017/00867 , A61B2017/00876 , A61B2017/1205 , A61B2090/3966 , A61F2/86 , A61F2002/043 , A61F2002/482
摘要： Provided are devices, systems and methods of selectively controlling air flow into one or more section of a patient's lungs. In particular, the devices may be valve devices (100) having an inner lumen (105) configured to transition between a first diameter and a second diameter smaller than the first diameter to control the airflow through the valve.
摘要翻译：提供了选择性地控制进入患者肺的一个或多个部分的空气流的装置，系统和方法。特别地，这些装置可以是具有内腔（105）的阀装置（100），该内腔被配置成在小于第一直径的第一直径和第二直径之间转变，以控制通过阀的气流。

17. 发明申请

WO2010104643A3 THIN PROFILE CONDUCTOR ASSEMBLY FOR MEDICAL DEVICE LEADS 审中-公开
标题翻译：医疗设备导线薄型导线器总成
公开(公告)号：WO2010104643A3
公开(公告)日：2010-11-18
申请号：PCT/US2010024062
申请日：2010-02-12
申请人： CARDIAC PACEMAKERS INC , SCHEUERMANN TORSTEN
发明人： SCHEUERMANN TORSTEN
IPC分类号： A61N1/08 , A61N1/05 , H05K9/00
CPC分类号： A61N1/056 , A61N1/086
摘要： A medical device lead includes a thin profile conductor assembly. A proximal connector includes a proximal end that is configured to couple the lead to a pulse generator. An insulative lead body extends distally from the proximal connector. The conductor assembly extends distally from the proximal end within the lead body and includes a non-conductive tubular core member that defines a lumen, an outer insulative layer, and a multilayer conductor between the tubular core member and the outer insulative layer. The multilayer conductor is electrically connected to the proximal connector and includes a first conductive layer adjacent to the tubular core member and a second conductive layer adjacent to the first conductive layer opposite the tubular core member. A conductivity of the second conductive layer is greater than a conductivity of the first conductive layer.
摘要翻译：医疗器械引线包括薄型导体组件。近端连接器包括被配置为将引线耦合到脉冲发生器的近端。绝缘引线体从近端连接器向远侧延伸。导体组件从引线主体内的近端向远侧延伸，并且包括在管芯和外绝缘层之间限定内腔，外绝缘层和多层导体的非导电管状芯构件。所述多层导体电连接到所述近端连接器，并且包括与所述管状芯部件相邻的第一导电层和与所述管状芯部件相对的所述第一导电层相邻的第二导电层。第二导电层的导电率大于第一导电层的导电率。

18. 发明申请

WO2009059129A3 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 审中-公开
标题翻译：具有多孔储层和非聚合物扩散层的内部结构
公开(公告)号：WO2009059129A3
公开(公告)日：2010-06-03
申请号：PCT/US2008081986
申请日：2008-10-31
申请人： BOSTON SCIENT LTD , SCHEUERMANN TORSTEN , WEBER JAN , CLARKE JOHN A
发明人： SCHEUERMANN TORSTEN , WEBER JAN , CLARKE JOHN A
IPC分类号： A61L31/08 , A61L31/14 , A61L31/16
CPC分类号： A61L31/082 , A61L31/146 , A61L31/16 , A61L2300/608 , A61L2420/08
摘要： An endoprosthesis such as a coronary stent includes a porous reservoir of drug, e.g., a porous layer formed of a ceramic and an overlayer formed of ceramic or metal for controlling elution of drug from the reservoir.
摘要翻译：诸如冠状动脉支架的内置假体包括多孔的药物储存器，例如由陶瓷形成的多孔层和由陶瓷或金属形成的覆盖层，用于控制药物从贮存器的洗脱。

19. 发明申请

WO2010107530A3 POROUS FIBER ELECTRODE COATING AND RELATED METHODS 审中-公开
标题翻译：多孔纤维电极涂层及相关方法
公开(公告)号：WO2010107530A3
公开(公告)日：2010-11-04
申请号：PCT/US2010023749
申请日：2010-02-10
申请人： CARDIAC PACEMAKERS INC , SCHEUERMANN TORSTEN
发明人： SCHEUERMANN TORSTEN
IPC分类号： A61N1/05 , A61L29/08 , A61L31/00 , A61L31/08
CPC分类号： A61N1/056 , A61B5/042 , A61B2562/0209
摘要： The embodiments herein relate to an electrode having a porous coating including a fiber mesh, a multi-layer coating, and an outer coating, and a method of making the same. The various electrode coating embodiments include pores in the coating that prevent access by protein or cells while allowing for ion and/or liquid access.
摘要翻译：本文中的实施例涉及具有包括纤维网，多层涂层和外部涂层的多孔涂层的电极及其制造方法。各种电极涂层实施方案包括涂层中的孔，其允许离子和/或液体进入时阻止蛋白质或细胞进入。

20. 发明申请

WO2009059166A2 ENDOPROSTHESIS WITH POROUS RESERVOIR AND NON-POLYMER DIFFUSION LAYER 审中-公开
标题翻译：具有多孔储层和非聚合物扩散层的内部结构
公开(公告)号：WO2009059166A2
公开(公告)日：2009-05-07
申请号：PCT/US2008082032
申请日：2008-10-31
申请人： BOSTON SCIENT LTD , SCHEUERMANN TORSTEN , WEBER JAN
发明人： SCHEUERMANN TORSTEN , WEBER JAN
IPC分类号： A61L31/08 , A61L31/14 , A61L31/16
CPC分类号： A61L31/146 , A61L31/022 , A61L31/082
摘要： An endoprosthesis such as a coronary stent includes a porous reservoir of drug, e.g., directly in the body of the stent, and an overlayer formed of ceramic or metal for controlling elution of drug from the reservoir.
摘要翻译：诸如冠状动脉支架的内假体包括药物的多孔储存器，例如直接在支架的主体中，以及由陶瓷或金属形成的覆盖层，用于控制药物从贮存器的洗脱。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式