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111. 发明申请

WO2015116397A1 INSULIN MANAGEMENT 审中-公开
标题翻译：胰岛素管理
公开(公告)号：WO2015116397A1
公开(公告)日：2015-08-06
申请号：PCT/US2015/011559
申请日：2015-01-15
申请人： ASEKO, INC.
发明人： BOOTH, Robert, C. , HEBBLEWHITE, Harry
IPC分类号： A61M5/14 , A61M5/168 , A61B5/145 , G06F19/00 , G06Q50/22 , A61J7/00
CPC分类号： G16H20/17 , A61B5/14532 , A61B5/4839 , A61B5/4848 , A61M5/14 , A61M5/1723 , A61M2005/14208 , A61M2005/14296 , A61M2005/1726 , A61M2205/18 , A61M2205/3327 , A61M2205/35 , A61M2205/3553 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/507 , A61M2205/52 , A61M2205/581 , A61M2230/201 , G06F19/00 , G06F19/3418 , G06F19/3468 , G16H10/40 , G16H40/67 , G16H80/00
摘要： A method of administering insulin includes receiving blood glucose measurements (BG) of a patient (10) at a data processing device (112) from a glucometer (124). Each blood glucose measurement (BG) is separated by a time interval (T Next ) and includes a blood glucose time ( BG- Time ) associated with a time of measuring the blood glucose measurement. The method also includes receiving patient information (208a) at the data processing device and selecting a subcutaneous insulin treatment program for tube-fed patients (1000) from a collection of subcutaneous insulin treatments (900, 1000, 1100, 1200, 1300, 1400). The selection is based on the blood glucose measurements and the patient information. The subcutaneous insulin treatment program for tube-fed patients determines recommended insulin doses based on the blood glucose times. The method also includes executing, using the data processing device, the selected subcutaneous insulin treatment program for tube-fed patients (1000).
摘要翻译：一种施用胰岛素的方法包括从血糖仪（124）在数据处理装置（112）处接收患者（10）的血糖测量值（BG）。每个血糖测量（BG）以时间间隔（TNext）分离，并且包括与测量血糖测量的时间相关联的血糖时间（BG-Time）。该方法还包括在数据处理装置处接收患者信息（208a），并从皮下胰岛素治疗（900,1000,1100,1200,1300,1400）的集合中选择管饲患者（1000）的皮下胰岛素治疗程序，。选择是基于血糖测量和患者信息。用于管饲患者的皮下胰岛素治疗程序根据血糖时间确定推荐的胰岛素剂量。该方法还包括使用数据处理装置执行所选择的用于管饲患者的皮下胰岛素治疗程序（1000）。

112. 发明申请

WO2015115898A1 METHOD FOR TREATING, STABILIZING OR SLOWING DOWN BRAIN GLUCOSE METABOLISM DEFICIT 审中-公开
标题翻译：治疗，稳定或缓解脑部葡萄糖代谢缺陷的方法
公开(公告)号：WO2015115898A1
公开(公告)日：2015-08-06
申请号：PCT/NL2015/050064
申请日：2015-02-02
申请人： N.V. NUTRICIA
发明人： BROERSEN, Ladislaus Maria , HAGEMAN, Robert Johan Joseph , LANSBERGEN, Marieke , GROENENDIJK, Martine , DE WILDE, Mattheus Cornelis
IPC分类号： A23L1/30 , A61K45/06 , A61K31/14 , A61K31/202 , A61K31/355 , A61K31/375 , A61K31/4415 , A61K31/519 , A61K31/683 , A61K31/685 , A61K31/7068 , A61K31/7072 , A61K31/714 , A61K33/04 , A61P25/28
CPC分类号： A61K31/7068 , A23L33/12 , A23L33/13 , A61B5/14532 , A61B5/4848 , A61B6/037 , A61B6/501 , A61K31/14 , A61K31/202 , A61K31/355 , A61K31/375 , A61K31/4415 , A61K31/519 , A61K31/683 , A61K31/685 , A61K31/7072 , A61K31/714 , A61K33/04 , A61K45/06 , A61K51/0491 , A61K2300/00
摘要： The invention pertains to the use of (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof, and (ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof in the manufacture of a composition for use in a method for treating, stabilizing or slowing down brain glucose metabolism deficit in a subject in need thereof.
摘要翻译：本发明涉及（i）尿苷和胞苷或其盐，磷酸酯，酰基衍生物或酯中的一种或多种和（ii）包含以下物质中的至少一种的脂质部分的用途：二十二碳六烯酸（22:6; DHA），二十碳五烯酸（20:5; EPA）和二十二碳五烯酸（22:5; DPA）或其酯在制备用于治疗，稳定或减缓在有需要的受试者中脑葡萄糖代谢缺陷。

113. 发明申请

WO2015103556A1 INSTRUMENTED WOUND CLOSURE DEVICE 审中-公开
标题翻译：仪器封闭装置
公开(公告)号：WO2015103556A1
公开(公告)日：2015-07-09
申请号：PCT/US2015/010188
申请日：2015-01-05
申请人： ZIPLINE MEDICAL, INC.
发明人： BELSON, Amir , DRISCOLL, Edward, C., Jr. , STORNE, Eric , SCHAER, Alan
IPC分类号： A61B17/08
CPC分类号： A61B5/4848 , A61B5/0015 , A61B5/01 , A61B5/1118 , A61B5/1121 , A61B5/14532 , A61B5/14539 , A61B5/14542 , A61B5/6832 , A61B5/746 , A61B17/08 , A61B17/085 , A61B2017/00022 , A61B2017/00075 , A61B2017/00084 , A61B2017/00221 , A61B2017/00407 , A61B2017/0073 , A61B2017/00876 , A61B2017/00893 , A61B2017/086 , A61B2090/064 , A61B2562/0219 , A61B2562/0223 , A61B2562/0261 , A61B2562/0266 , A61F7/007 , A61F2007/0052 , A61F2007/0056 , A61H23/00 , A61H23/02 , A61H23/0245 , A61H2201/0184 , A61H2201/0207 , A61H2201/0214 , A61H2201/0242 , A61H2201/10 , A61H2201/105 , A61H2201/165 , A61H2201/5015 , A61H2201/5058 , A61H2201/5061 , A61H2201/5064 , A61H2201/5084 , A61H2201/5092 , A61H2201/5097 , A61H2230/00 , A61H2230/205 , A61H2230/207 , A61H2230/505 , A61M31/002 , A61N1/00 , A61N5/0616 , A61N5/0624 , A61N7/00
摘要： A wound or incision closure apparatus comprises a first and second panel. Each of the panels comprises a bottom adhesive layer, a medial substrate layer, and an upper load distribution layer which connect the two panels. A sensory or therapeutic element is disposed adjacent, within, or between two or more of the layers. The sensory or therapeutic element can provide sensing and/or therapy for the incision and/or monitor the incision so that the therapy can be customized and updated.
摘要翻译：伤口或切口封闭装置包括第一和第二面板。每个面板包括底部粘合剂层，中间基底层和连接两个面板的上部负载分布层。感觉或治疗元件设置在两层或更多层之间，内或之内。感觉或治疗元件可以为切口提供感测和/或治疗以及/或监视切口，使得可以定制和更新治疗。

114. 发明申请

WO2015102728A1 HANDS-FREE INTERFACE 审中-公开
标题翻译：无障碍接口
公开(公告)号：WO2015102728A1
公开(公告)日：2015-07-09
申请号：PCT/US2014/061115
申请日：2014-10-17
申请人： GOOGLE INC.
发明人： PLETCHER, Nathan , NELSON, Andrew , HONORE, Francis
IPC分类号： G06F1/16 , G02C7/02
CPC分类号： A61B5/0026 , A61B5/0015 , A61B5/1126 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/6821 , A61B2560/0204 , A61B2560/0214 , A61B2560/0487 , A61B2562/164 , A61B2562/166 , G06F3/013 , G06F3/017
摘要： A wearable device and external reader is provided for herein. In some embodiments of the present disclosure, the wearable device or the reader is configured to receive a level of radiant energy, detect a change in the received level of radiant energy, determine that the detected change in the received level of radiant energy is indicative of a predetermined pattern of received radiant energy, and responsively operate (or cause to be operated via the external reader) one or more external devices.
摘要翻译：本文提供了可穿戴设备和外部读取器。在本公开的一些实施例中，可穿戴设备或读取器被配置为接收辐射能量的水平，检测所接收的辐射能量的变化，确定检测到的接收到的辐射能量的变化指示接收的辐射能的预定模式，并且响应地操作（或导致经由外部读取器操作）一个或多个外部设备。

115. 发明申请

WO2015100265A1 SENSOR ELECTRODES IN A BIO-COMPATIBLE DEVICE 审中-公开
标题翻译：传感器电极在一个生物兼容的设备
公开(公告)号：WO2015100265A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/071985
申请日：2014-12-22
申请人： GOOGLE INC.
发明人： ETZKORN, James , HO, Harvey , LIU, Zenghe
IPC分类号： G06K9/00
CPC分类号： A61B5/6821 , A61B5/0002 , A61B5/14532 , A61B5/1486 , Y10T29/49155
摘要： A method may involve providing a conductive pattern on a bio-compatible layer. The conductive pattern may include a first conductive layer that comprises a first metal and a second conductive layer that comprises a second metal. The second conductive layer may be over the first conductive layer, and the first metal may be more malleable than the second metal. The method may also include mounting an electrical component to the conductive pattern to provide an electrochemical sensor. The electrochemical sensor may be configured for use in a body-mountable device.
摘要翻译：一种方法可以涉及在生物相容层上提供导电图案。导电图案可以包括第一导电层，其包括第一金属和包括第二金属的第二导电层。第二导电层可以在第一导电层之上，并且第一金属可以比第二金属更具有延展性。该方法还可以包括将电气部件安装到导电图案以提供电化学传感器。电化学传感器可被配置为用于体内安装的装置。

116. 发明申请

WO2015100200A1 TEST STRIP CONNECTOR CONTACT PROTECTION 审中-公开
标题翻译：测试条连接器接触保护
公开(公告)号：WO2015100200A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/071806
申请日：2014-12-22
申请人： CILAG GMBH INTERNATIONAL , WALSH, Ryan
发明人： WALSH, Ryan , ELDER, David , SETFORD, Steven , FAULKNER, Allan
IPC分类号： A61B5/145 , G01N27/327 , G01N33/487
CPC分类号： G01N33/4875 , A61B5/14532 , G01N27/3273
摘要： A test strip port connector (200, 300, 400) of a test meter receives an analytical test strip (206, 406) comprising a sample chamber for receiving a fluid sample. The fluid sample is prevented from contaminating an interior region of the test strip port connector by a sealing mechanism having a seal (203, 205, 403) configured to be moved into a sealing position across the test strip.
摘要翻译：测试仪的测试条端口连接器（200,300,400）接收包括用于接收流体样品的样品室的分析测试条（206,406）。通过具有密封件（203,205,403）的密封机构防止流体样品污染测试条端口连接器的内部区域，该密封机构被配置为移动到穿过测试条的密封位置。

117. 发明申请

WO2015100131A1 ANALYTE SENSORS WITH ETHYLENE OXIDE IMMUNITY 审中-公开
标题翻译：具有乙烯氧化物免疫力的分析仪传感器
公开(公告)号：WO2015100131A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/071170
申请日：2014-12-18
申请人： GOOGLE INC.
发明人： LIU, Zenghe
IPC分类号： C12Q1/26 , G01N27/30
CPC分类号： A61L2/206 , A61B5/14532 , A61B5/14546 , A61B5/1486 , A61B5/682 , A61B5/6821 , C12Q1/006
摘要： Analyte sensors capable of undergoing sterilization with ethylene oxide are provided. The analyte sensors can include one or more polymer membranes having a nucleophilic group.
摘要翻译：提供能够与环氧乙烷进行灭菌的分析物传感器。分析物传感器可以包括具有亲核基团的一个或多个聚合物膜。

118. 发明申请

WO2013119951A3 DIGITAL ASIC SENSOR PLATFORM 审中-公开
标题翻译：数字ASIC传感器平台
公开(公告)号：WO2013119951A3
公开(公告)日：2015-06-18
申请号：PCT/US2013025346
申请日：2013-02-08
申请人： SENSEONICS INC
发明人： DEHENNIS ANDREW , COLVIN ARTHUR E
IPC分类号： A61B5/145
CPC分类号： A61B5/1455 , A61B5/0031 , A61B5/076 , A61B5/1451 , A61B5/14532 , A61B5/14551 , A61B5/14552 , A61B5/14556 , A61B5/1459 , A61B5/6861 , A61B5/7225
摘要： The present invention relates to an optical sensor that may be implanted within a living animal (e.g., a human) and may be used to measure the concentration of an analyte in a medium within the animal. The optical sensor may wirelessly receive and may be capable of bi-directional data communication. The optical sensor may include a semiconductor substrate in which various circuit components, one or more photodectors and/or a light source may be fabricated. The circuit components fabricated in the semiconductor substrate may include a comparator, an analog to digital converter, a temperature transducer, a measurement controller, a rectifier and/or a nonvolatile storage medium. The comparator may output a signal indicative of the difference between the outputs of first and second photodetectors. The measurement controller may receive digitized temperature, photodetector and/or comparator measurements and generate measurement information, which may be wirelessly transmitted from the optical sensor.
摘要翻译：本发明涉及一种可以植入活体动物（例如人）中的光学传感器，并可用于测量动物中介质中分析物的浓度。光学传感器可以无线地接收并且可能能够进行双向数据通信。光学传感器可以包括其中可以制造各种电路部件，一个或多个光电探测器和/或光源的半导体衬底。制造在半导体衬底中的电路部件可以包括比较器，模数转换器，温度传感器，测量控制器，整流器和/或非易失性存储介质。比较器可以输出指示第一和第二光电检测器的输出之间的差的信号。测量控制器可以接收数字化的温度，光电检测器和/或比较器测量并产生可以从光学传感器无线传输的测量信息。

119. 发明申请

WO2015084570A1 SENSOR MEMBRANE WITH LOW TEMPERATURE COEFFICIENT 审中-公开
标题翻译：具有低温系数的传感器膜
公开(公告)号：WO2015084570A1
公开(公告)日：2015-06-11
申请号：PCT/US2014/065905
申请日：2014-11-17
申请人： GOOGLE INC.
发明人： LIU, Zenghe
IPC分类号： G01N27/30 , G01N33/50 , C08L33/14
CPC分类号： C12Q1/006 , A61B5/14532 , A61B5/1486 , A61B5/6821 , C12Q1/002
摘要： An analyte sensor for measuring physiological parameters, a method for making the analyte sensor, and method of measuring a level of an analyte in a subject are disclosed. In one aspect, the analyte sensor includes a crosslinked, hydrophilic copolymer in contact with a surface of an electrode, and an analyte sensing component embedded within the crosslinked, hydrophilic copolymer. The crosslinked, hydrophilic copolymer has methacrylate-derived backbone chains of first methacrylate-derived units, second methacrylate-derived units and third methacrylate-derived units. The first and second methacrylate-derived units have side chains that can be the same or different, and the third methacrylate-derived units in different backbone chains are connected by hydrophilic crosslinks. The crosslinked, hydrophilic copolymer has an analyte permeability that is substantially temperature independent. The analyte sensor generates signals that are substantially temperature independent over a range of temperatures.
摘要翻译：公开了一种用于测量生理参数的分析物传感器，用于制备分析物传感器的方法和测量受试者中分析物水平的方法。一方面，分析物传感器包括与电极表面接触的交联的亲水共聚物和嵌入交联的亲水共聚物内的分析物感测组分。交联的亲水共聚物具有衍生自第一甲基丙烯酸酯单元，第二甲基丙烯酸酯衍生单元和第三甲基丙烯酸酯衍生单元的甲基丙烯酸酯衍生的主链。第一和第二甲基丙烯酸酯衍生单元具有可以相同或不同的侧链，并且不同主链中的第三甲基丙烯酸酯衍生单元通过亲水性交联连接。交联的亲水共聚物具有基本上独立于温度的分析物渗透性。分析物传感器产生在温度范围内基本上独立于温度的信号。

120. 发明申请

WO2014210288A3 A METHOD AND SYSTEM FOR MANAGING METADATA FROM BODILY FLUID ANALYZERS 审中-公开
标题翻译：一种用于从体液分析仪管理元数据的方法和系统
公开(公告)号：WO2014210288A3
公开(公告)日：2015-06-11
申请号：PCT/US2014044301
申请日：2014-06-26
申请人： FUISZ RICHARD C , FUISZ JOSEPH M
发明人： FUISZ RICHARD C , FUISZ JOSEPH M
IPC分类号： G08B21/02 , G08B21/00
CPC分类号： G06F19/3418 , A61B5/14532 , A61B5/7282 , G16H50/20
摘要： A method and system are provided for electronically delivering to a caregiver analytical result and alert data concerning a breach or non breach of an alert limit for an analyte. The method includes providing a medical analyzer with at least one threshold value for the at least one analyte to be sensed by the medical analyzer, sensing the analyte level; and, if the sensed analyte level is beyond the threshold value, electronically sending data to the caregiver, the data comprising an indication of the analyte and the limits set by the caregiver, a breach of the threshold value, the degree of the breach on the basis of an amount over or under the threshold value, a time interval between breaches whether fixed or rolling, a total number of breaches in a given time cycle, and the total number of tests in the time period.
摘要翻译：提供了一种方法和系统，用于电子地传递给护理人员的分析结果，并提供有关分析物的违反或不违反警报限制的数据。该方法包括向医学分析仪提供至少一个待由医学分析仪感测的分析物的阈值，感测分析物水平; 并且如果感测到的分析物水平超过阈值，则将数据电子地发送给照料者，该数据包括被分析物的指示和照料者设定的限度，违反阈值，违反阈值的程度超过或低于阈值的金额的基础，违约的固定或滚动之间的时间间隔，给定时间周期中的违规总数以及该时间段内的总体测试次数。

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