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1. 发明申请

WO1996029030A1 MEDICAL IMPLANTS 审中-公开
标题翻译：医用植绒
公开(公告)号：WO1996029030A1
公开(公告)日：1996-09-26
申请号：PCT/US1996003619
申请日：1996-03-15
申请人： SMITH & NEPHEW RICHARDS INC.
发明人： SMITH & NEPHEW RICHARDS INC. , MISHRA, Ajit, K. , DAVIDSON, James, A. , HAMBY, Mark, A.
IPC分类号： A61F02/28
CPC分类号： A61F2/30767 , A61F2/3094 , A61F2/3859 , A61F2/389 , A61F2002/30321 , A61F2002/30906 , A61F2002/30976 , A61F2250/0025 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00071 , A61F2310/00089 , A61F2310/00095 , A61F2310/00131 , A61F2310/00179 , B08B3/02 , B08B7/02 , B24C1/003 , Y10S623/901
摘要： Many medical implants have roughened surfaces that promote cell, bone or tissue adhesion as well as the adhesion of bone cement, for better affixing of the implants in the body. The roughened surfaces should be free of particulates, such as commonly arise from the blasting of implant surfaces with particulates to produce a desired surface finish. A method of producing implants with implant surfaces free of such particulates is to blast the implant surface with a biocompatible liquid, such as water, under high pressure. Under certain circumstances, a solvent may contain particulates that assist in producing the roughened surface, and the particulates are dissolved, sublimated or vaporized from the implant surface, leaving no particulate residue.
摘要翻译：许多医疗植入物具有促进细胞，骨或组织粘附以及骨粘固的粘附的粗糙表面，以便更好地将植入物粘附在体内。粗糙表面应不含微粒，如通常由具有颗粒物的植入物表面喷砂产生所需表面光洁度。用不含这种颗粒的植入物表面生产植入物的方法是在高压下用生物相容性液体例如水轰击植入物表面。在某些情况下，溶剂可能含有有助于生产粗糙表面的微粒，并且微粒从植入物表面溶解，升华或蒸发，不留下颗粒残留物。

2. 发明申请

WO1994016836A1 CLEANING POROUS AND ROUGHENED SURFACES ON MEDICAL IMPLANTS 审中-公开
标题翻译：清洁多孔和粗糙的表面在医疗植入物
公开(公告)号：WO1994016836A1
公开(公告)日：1994-08-04
申请号：PCT/US1994000877
申请日：1994-01-21
申请人： SMITH & NEPHEW RICHARDS, INC.
发明人： SMITH & NEPHEW RICHARDS, INC. , DAVIDSON, James, A. , MISHRA, Ajit, K.
IPC分类号： B08B07/00
CPC分类号： B24C1/086 , A61B90/70 , A61F2/30767 , A61F2002/30719 , A61F2002/30906 , A61F2002/30968 , A61F2250/0092 , A61F2310/00389 , A61N7/00 , B08B3/12 , B08B7/00 , B24C1/003 , B24C11/00
摘要： A method for the cleaning of roughened surface or porous-coated medical implants of all kinds. In the cleaning method, the roughened surface or porous-coated implant is subjected to blasting with particulate solids selected from the solids that are soluble in a biocompatible non-toxic solvent and solids that deliquesce, sublimate, or vaporize. The particulate solids must be sufficiently hard to provide effective impact for dislodging debris and loosely attached particles from implant surfaces. After blasting, the surface is optionally treated with ultrasonic vibration to further remove debris particulates. The impacted surfaces may also be rinsed with a biocompatible liquid. After cleaning, the surfaces may be passivated by immersion in conventional passivation solutions or a solution of non-aggressive oxyanions.
摘要翻译：一种清洁各种粗糙面或多孔涂层医用植入物的方法。在清洁方法中，将粗糙表面或多孔涂覆的植入物用选自可溶于生物相容性无毒溶剂的固体和溶解，升华或蒸发的固体进行喷砂处理。颗粒固体必须足够硬以便为植入物表面上的碎屑和松散附着的颗粒提供有效的冲击。爆破后，表面任选地用超声波振动处理，以进一步去除碎屑颗粒。受冲击的表面也可以用生物相容性液体冲洗。在清洁之后，可以通过浸入常规钝化溶液或非侵蚀性含氧阴离子溶液来钝化表面。

3. 发明申请

WO1996023908A1 WEAR RESISTANT TRIBOSYSTEM 审中-公开
标题翻译：耐磨性研究
公开(公告)号：WO1996023908A1
公开(公告)日：1996-08-08
申请号：PCT/US1996001123
申请日：1996-01-23
申请人： SMITH & NEPHEW RICHARDS INC.
发明人： SMITH & NEPHEW RICHARDS INC. , MISHRA, Ajit, K. , POGGIE, Robert, A. , DAVIDSON, James, A.
IPC分类号： C22C14/00
CPC分类号： C23C8/10
摘要： Surface and near surface hardened wear resistant tribological system articles of manufacture are provided. These tribological system articles are fabricated from titanium alloys that contain an amount of zirconium sufficient to permit the formation of a significant amount of zirconium oxide at the surface of the article to cause surface hardening and improved wear and abrasion resistance. Further, the zirconium-containing titanium alloy tribological articles are characterized in having an alloy substrate with an oxygen-rich layer surrounding the substrate, and a surface layer, overlying the oxygen-rich layer, including mixed oxides of the metals present in the alloy. A zirconium-rich interface may sometimes be present between the oxygen-rich layer and the mixed-oxide surface layer. The method of producing these surface hardened articles includes the steps of heating the article in an oxygen containing environment at a temperature sufficient to allow oxygen to diffuse to and react with the surface and near surface.
摘要翻译：提供表面和近表面硬化耐磨摩擦学系统制造制品。这些摩擦系统制品由钛合金制成，其含有足以允许在制品表面形成大量氧化锆的量的锆，以引起表面硬化和改善的耐磨性和耐磨性。此外，含锆的钛合金摩擦学制品的特征在于具有围绕基板的富氧层的合金基板和覆盖富氧层的包含合金中存在的金属的混合氧化物的表面层。在富氧层和混合氧化物表面层之间有时可能存在富锆界面。制造这些表面硬化制品的方法包括在足够使氧气扩散到表面和近表面并与其反应的温度下在含氧环境中加热制品的步骤。

4. 发明申请

WO1995034251A1 BIOCOMPATIBLE LOW MODULUS DENTAL DEVICES 审中-公开
标题翻译：生物降解低密度牙科设备
公开(公告)号：WO1995034251A1
公开(公告)日：1995-12-21
申请号：PCT/US1995007607
申请日：1995-06-16
申请人： SMITH & NEPHEW RICHARDS, INC.
发明人： SMITH & NEPHEW RICHARDS, INC. , DAVIDSON, James, A. , MISHRA, Ajit, K. , DAIGLE, Kenneth, P. , KOVACS, Paul
IPC分类号： A61C08/00
CPC分类号： A61K6/024 , A61C7/12 , A61C7/282 , A61C8/0012 , A61C8/0013 , A61F2/0077 , A61K6/04 , A61L27/06 , A61L27/507 , A61L31/022 , A61L33/022 , A61L2430/12 , A61N1/05 , A61N1/056 , C22C14/00
摘要： The invention provides dental devices (including implants (40), abutments (12), bridges, screws (15), and orthodontic appliances (50, 51, 52)) that are fabricated from low modulus, biocompatible, non-toxic Ti-Nb-Zr alloys. The dental implants provide a biomaterial-to-bone interface that results in significant attachment between implant and bone. The implants may be supplied with a porous coating or macro-texture to further promote bone attachment and stabilization of the implant in the jaw bone. Other orthodontic appliances such as brackets (50) and wires (51) have improved elastic toughness and corrosion resistance so that they provide superior performance and corrosion characteristics.
摘要翻译：本发明提供了由低模量，生物相容性，无毒的Ti-Nb制成的牙科设备（包括植入物（40），基台（12），桥梁，螺钉（15）和正畸器具（50,51,52）） -Zr合金。牙种植体提供生物材料与骨界面，其导致植入物和骨之间的显着附着。可以向植入物提供多孔涂层或宏观结构，以进一步促进植入物在颚骨中的骨附着和稳定。其他矫正器具如支架（50）和电线（51）具有改善的弹性韧性和耐腐蚀性，从而提供优异的性能和腐蚀特性。

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