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    • 7. 发明申请
    • Coating process
    • 涂层工艺
    • US20030138572A1
    • 2003-07-24
    • US10291944
    • 2002-11-11
    • Hermann Neuhaus-SteinmetzLars GuldbrandsenMaren Klose
    • B05D001/04
    • B05D1/265B05D1/007B05D3/14
    • A process for producing products in web form comprising at least two layers, in which a composition emerging from an applicator is applied as a layer to a substrate in web form which is guided on a transport means, said application taking place with application of electrostatic charges, and in which the substrate coated with the composition is electrostatically neutralized before departing the transport means, electrostatic charges being applied to the web-formed substrate prior to coating, by means of a substrate electrode, so that the substrate is pressed onto the transport means.
    • 一种用于生产纤维网形式的产品的方法,其包括至少两层,其中将从施用器出来的组合物作为一层施加到以传送装置为导向的网状的基材上,所述施用在施加静电荷的情况下发生 ,并且其中涂覆有组合物的基材在离开输送装置之前被静电中和,在涂覆之前通过基底电极将静电荷施加到幅材形成的基底上,使得基底被压在输送装置上 。
    • 10. 发明申请
    • Method and apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
    • 用于将药物粉末静电沉积在基底的预定区域上的方法和装置
    • US20020176926A1
    • 2002-11-28
    • US10047183
    • 2001-10-23
    • Timothy Allen PletcherPabitra DattaChristopher Just PouxRandall Eugene McCoy
    • B05D001/04B05D001/12A61J001/00B05D003/00B01J013/00
    • A61K9/0075A61J3/00A61K9/0073A61M15/0045A61M15/0048A61M15/02A61M15/025B05B5/025B05B5/047G03G15/04045G03G15/221G03G15/323
    • Apparatus and a concomitant method for electrostatically depositing select doses of medicament powder at select locations on a substrate. Specifically, the apparatus contains a charged particle emitter for generating charged particles that charge a predefined region of a substrate and a charge accumulation control circuit for computing the amount of charge accumulated upon the substrate and deactivating the emitter when a selected quantity of charge has accumulated. Additionally, a triboelectric charging apparatus charges the medicament powder and forms a charged medicament cloud proximate the charged region of the substrate. The medicament particles within the medicament cloud electrostatically adhere to the charged region. The quantity of charge accumulated on the substrate at the predefined region and the charge-to-mass ratio of the medicament powder in the cloud control the amount (dose) of medicament deposited and retained by the substrate. Consequently, this apparatus accurately controls both medicament dosage and deposition location. Furthermore, since the substrate can be of any dielectric material that retains an electrostatic charge, the apparatus can be used to deposit medicament on substrates that are presently used in oral medicament consumption, e.g., substrates that are used to fabricate suppositories, inhalants, tablets, capsules and the like.
    • 用于在基底上的选定位置静电沉积选择剂量的药物粉末的装置和伴随方法。 具体地,该装置包含用于产生对基板的预定区域充电的带电粒子的带电粒子发射器和用于计算在基板上累积的电荷量并且在已选择的电荷积累时停用发射极的电荷累积控制电路。 此外,摩擦带电装置对药物粉末进行充电,并在基底的带电区域附近形成带电药物云。 药物云内的药物颗粒静电附着到带电区域。 在预定区域上积累在基底上的电荷量和云中的药物粉末的电荷与质量比控制由基底沉积和保留的药物的量(剂量)。 因此,该装置精确地控制药物剂量和沉积位置。 此外,由于衬底可以是保持静电电荷的任何电介质材料,所以该装置可用于在目前用于口服药物消耗的基底上沉积药物,例如用于制造栓剂,吸入剂,片剂, 胶囊等。