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1. 发明授权

US06821480B2 Water line decontamination system 有权
标题翻译：水线净化系统
公开(公告)号：US06821480B2
公开(公告)日：2004-11-23
申请号：US10052048
申请日：2002-01-17
申请人： James N. Suddath , William Piskorowski , Jerome J. Kasbrick
发明人： James N. Suddath , William Piskorowski , Jerome J. Kasbrick
IPC分类号： A61L200
CPC分类号： A61L2/07 , A61C1/0076 , A61L2/16 , B01D3/42 , C02F1/04 , C02F1/50 , C02F1/685 , C02F5/00 , C02F2103/006
摘要： A self-cleaning system for delivering sanitized water to a workstation has a boiler which produces heat-sanitized water and steam. A diverter valve permits a fluid delivery line of the system to convey either sanitized water or steam to a workstation. The steam serves to sanitize the delivery line and workstation and removes biofilms therefrom.
摘要翻译：将消毒水送至工作站的自清洁系统具有生产热消毒水和蒸汽的锅炉。分流阀允许系统的流体输送管线将消毒水或蒸汽输送到工作站。蒸汽用于消毒输送管线和工作站，并从中除去生物膜。

2. 发明授权

US06814931B2 Method and apparatus for treating an object with ozone 失效
公开(公告)号：US06814931B2
公开(公告)日：2004-11-09
申请号：US10326484
申请日：2002-12-20
申请人： Herbert J. Kaiser
发明人： Herbert J. Kaiser
IPC分类号： A61L200
CPC分类号： A61L2/202 , A61L2/10 , A61L2/24 , C01B13/10
摘要： A treatment system for treating objects (e.g., medical instruments) with ozone gas. The ozone treatment system includes a treatment tank wherein the objects are exposed to ozone. In a preferred embodiment, the ozone is generated within the treatment tank by exposing an oxygen-containing gas to ultraviolet radiation produced by a laser.

3. 发明授权

US06793879B2 Four edge sealed sterilization wrap and method for sterilizing an article 有权
标题翻译：四边密封灭菌包装和物品灭菌方法
公开(公告)号：US06793879B2
公开(公告)日：2004-09-21
申请号：US10119183
申请日：2002-04-09
申请人： Robert T. Bayer , Brian G. Hoge , David G. Pasternack , William F. Church , James F. Whitaker , Stephen R. Everson
发明人： Robert T. Bayer , Brian G. Hoge , David G. Pasternack , William F. Church , James F. Whitaker , Stephen R. Everson
IPC分类号： A61L200
CPC分类号： B32B3/02 , A61B50/3001 , A61L2/26 , A61L2202/181 , A61L2202/24 , B32B7/08 , B32B27/32 , B32B2250/242 , B32B2323/10 , D04H5/08 , Y10T428/1303 , Y10T428/1307 , Y10T428/1334 , Y10T428/1352 , Y10T428/1362 , Y10T428/24777 , Y10T428/24793
摘要： There is provided an improved sterilization wrap and a method for using the improved sterilization wrap to sterilize an article. The wrap is made of a first and second sheets of sterilization material. Each sheet has first, second, third and fourth edges. Each sheet includes a central portion. The first edge of the first sheet is in register with and bonded to the first edge of the second sheet; the second edge of the first sheet is in register with and bonded to the second edge of the second sheet; the third edge of the first sheet is in register with and bonded to the third edge of the second sheet; and the fourth edge of the first sheet is in register with and bonded to the fourth edge of the second sheet. The central portions of the first and second sheets are substantially not bonded together. Thus, two layers of sterilization material is provided for an article to be sterilized.
摘要翻译：提供了改进的灭菌包装和使用改进的灭菌包装来对制品进行灭菌的方法。包装由第一和第二层灭菌材料制成。每个片材具有第一，第二，第三和第四边缘。每个片材包括一个中心部分。第一片材的第一边缘与第二片材的第一边缘对准并且结合到第二片材的第一边缘; 第一片的第二边缘与第二片的第二边缘对准并且结合到第二片的第二边缘; 第一片材的第三边缘与第二片材的第三边缘对准并结合到第二片材的第三边缘; 并且第一片材的第四边缘与第二片材的第四边缘对准并结合到第二片材的第四边缘。第一和第二片的中心部分基本上不结合在一起。因此，为待灭菌的物品提供两层灭菌材料。

4. 发明授权

US06767509B1 Self-sterilizing packaging 有权
标题翻译：自消毒包装
公开(公告)号：US06767509B1
公开(公告)日：2004-07-27
申请号：US09592034
申请日：2000-06-12
申请人： Henry L. Griesbach , Peter N. Gray
发明人： Henry L. Griesbach , Peter N. Gray
IPC分类号： A61L200
CPC分类号： A61L2/28 , A61L2/20 , B65B55/18
摘要： A sterilization system and process is provided which is useful in the chemical sterilization of medical supplies and equipment. The system includes a container having an internal generator of a sterilant such as chlorine dioxide. An internal container activator, such as high humidity or manual manipulation, is provided and stimulates the formation and release of the sterilant. The package includes a first indicator responsive to the release of sterilant and a second indicator which records the passage of a predetermined time interval. The combination of the sterilant indicator and the time interval indicator signals that proper sterilization conditions have been met and that the objects have been suitably sterilized.
摘要翻译：提供灭菌系统和方法，用于医疗用品和设备的化学灭菌。该系统包括具有灭菌剂如二氧化氯的内部发生器的容器。提供内部容器活化剂，例如高湿度或手动操作，并且刺激灭菌剂的形成和释放。包装包括响应于消毒剂释放的第一指示剂和记录预定时间间隔的通过的第二指示剂。消毒剂指示剂和时间间隔指示剂的组合表明已经满足适当的灭菌条件并且物体已被适当地消毒。

5. 发明授权

US06737020B1 Microorganism neutralization device and method 失效
标题翻译：微生物中和装置及方法
公开(公告)号：US06737020B1
公开(公告)日：2004-05-18
申请号：US09723731
申请日：2000-11-28
申请人： Isaac B. Horton, III , Kurt Anthony Garrett
发明人： Isaac B. Horton, III , Kurt Anthony Garrett
IPC分类号： A61L200
CPC分类号： C02F1/325 , A61L2/0011 , C02F1/725 , C02F2103/20 , C02F2201/3224 , C02F2201/3228 , C02F2201/326 , C02F2303/04 , C02F2305/10
摘要： A processing method for treating organics-containing fluids including a ultraviolet (UV) disinfection step and a biological processing step. The UV light source employed in the UV disinfection step is positioned outside the fluid to be disinfected and the fluid is disinfected via exposure to at least one UV dose zone outside the fluid being treated wherein UV light is projected into the at least one dose zone. The UV light source may be presented in a vertical riser configuration, wherein the UV light source is positioned above the fluid to be treated and projecting a UV dose zone downward toward and into the fluid to be treated, with the fluid moving upward toward the UV light source. At least one interface plate is used to provide a surface zone for UV disinfection above the fluid and to provide additional treatment means for balancing pH, affecting effluent chemistry, reducing organic chemicals, and the like. Alternatively, the UV light source may be presented in a planar or horizontal design, wherein the UV light source is positioned above the fluid to be treated and projecting a UV dose zone downward toward and into the fluid to be treated, with the fluid moving in a direction substantially perpendicular to the UV dose zone. After neutralization, the fluid is directed to the biological processing step, wherein microbes or enzymes are contacted with the fluid to effect metabolism of the organics in the fluid. The process may be used to reduce the organic load of animal and non-animal wastes, as well as produce a desired product from microbial foodstocks or enzyme substrates.
摘要翻译：一种处理含有有机物的流体的处理方法，包括紫外（UV）消毒步骤和生物处理步骤。在UV消毒步骤中使用的UV光源位于要消毒的流体的外部，并且通过暴露于待处理流体外的至少一个UV剂量区域来消毒流体，其中UV光投射到至少一个剂量区域中。 UV光源可以呈垂直提升管构造，其中UV光源位于待处理的流体上方，并且将UV剂量区域向下朝向并进入待处理流体中并且流体朝向UV移动光源。使用至少一个界面板来提供用于在流体上方进行紫外消毒的表面区域，并且提供用于平衡pH，影响流出物化学，还原有机化学品等的附加处理装置。或者，UV光源可以以平面或水平设计呈现，其中UV光源位于待处理流体上方，并且将UV剂量区域向下朝向并进入待处理流体中，并且流体移动到大致垂直于UV剂量区的方向。在中和之后，流体被引导到生物处理步骤，其中微生物或酶与流体接触以实现流体中有机物的代谢。该方法可用于减少动物和非动物废物的有机负载，以及从微生物食品原料或酶底物产生所需产物。

6. 发明授权

US06699434B1 Metering valve to deliver liquid 失效
标题翻译：计量阀输送液体
公开(公告)号：US06699434B1
公开(公告)日：2004-03-02
申请号：US09658312
申请日：2000-09-08
申请人： Robert G. Lukasik , Szu-Min Lin
发明人： Robert G. Lukasik , Szu-Min Lin
IPC分类号： A61L200
CPC分类号： A61L2/186 , A61L2/14 , A61L2/26 , A61L2202/122 , A61L2202/15 , Y10T137/86863
摘要： A metering valve for delivering liquids from a reservoir includes a rotatable valve plug having at least one well in the valve plug. The valve plug prevents direct communication across the valve. Rotating the valve plug transfers the liquid from the reservoir into the well on the valve plug. Rotating the valve plug further transfers the liquid in the well from the valve plug to the point of delivery. The rotation of the valve plug can be repeated to transfer more liquid. The metering valve can be used to deliver vaporizable germicides to a sterilization chamber. A single metering valve can be used to deliver varying amounts of vaporizable germicide to different sizes of sterilization chamber by rotating the valve plug an appropriate number of times. The valve plug can contain multiple wells to deliver large volumes of liquid quickly.
摘要翻译：用于从储存器输送液体的计量阀包括具有阀塞中的至少一个井的可旋转阀塞。阀塞可防止阀门间直接连通。旋转阀塞将液体从储存器转移到阀塞上的孔中。旋转阀塞进一步将井中的液体从阀塞转移到输送点。可以重复阀塞的旋转以转移更多的液体。计量阀可用于将可蒸发的杀菌剂输送到灭菌室。单个计量阀可用于通过旋转阀塞适当次数将不同量的可蒸发的杀菌剂输送到不同尺寸的灭菌室。阀塞可以容纳多个井，以快速输送大量的液体。

7. 发明授权

US06680025B2 Device and method for photoactivation 失效
标题翻译：用于光活化的装置和方法
公开(公告)号：US06680025B2
公开(公告)日：2004-01-20
申请号：US10236373
申请日：2002-09-06
申请人： David Paul Hearst , George D. Cimino , John Eugene Hearst , Stephen T. Isaacs
发明人： David Paul Hearst , George D. Cimino , John Eugene Hearst , Stephen T. Isaacs
IPC分类号： A61L200
CPC分类号： B01L7/52 , B01J19/123 , B01L7/00 , C07D493/04 , C12Q1/6848 , G11C11/412 , H01L27/11 , Y10S204/902 , C12Q2523/101 , C12Q2521/531
摘要： A device containing a light source, a sample support and a temperature control compartment. The sample support is positioned to support multiple sample vessels for irradiation by the light source. The temperature control compartment maintains the temperature of the sample vessels within a desired range. The light source, sample support and temperature control compartment are all contained within an opaque housing.
摘要翻译：包含光源，样品支架和温度控制室的装置。样品支架定位成支撑多个样品容器用于照射光源。温度控制室将样品容器的温度保持在所需的范围内。光源，样品支架和温度控制室都包含在不透明的外壳内。

8. 发明授权

US06652818B1 Implant sterilization apparatus 有权
标题翻译：种植体灭菌装置
公开(公告)号：US06652818B1
公开(公告)日：2003-11-25
申请号：US09378527
申请日：1999-08-20
申请人： C. Randal Mills , John F. Wironen , Sean Hanstke , Russell S. Donda , Jamie M. Grooms
发明人： C. Randal Mills , John F. Wironen , Sean Hanstke , Russell S. Donda , Jamie M. Grooms
IPC分类号： A61L200
CPC分类号： A61L2/0088 , A61L2/025
摘要： This invention includes a novel method for safely, effectively and efficiently pooling of tissues for treatment prior to implantation into a recipient in need thereof. In one embodiment, the method includes perfusion of a porous implant which achieves efficient interpenetration of desired factors into and removal of undesirable factors from the pores of the implant, cleaning of the implant, efficient passivation of the implant (inactivation of pathogens, microorganisms, cells, viruses and the like and reduction in antigenicity thereof), and the novel implant produced by such treatment. The process presents a system wherein the rate of pressure cycling, the fact of pressure cycling, and the amplitude of pressure cycling, results in highly cleaned tissues and other implants for implantation. Target decontamination goals for this process include between about a one (1) to twelve (12) log reduction in bacterial contamination, between about a one (1) to fifteen (15) log reduction in enveloped virus contamination, up to about a five (5) log reduction in non-enveloped virus contamination, between about a two (2) to ten (10) fold reduction in endotoxin, maintenance of implant or graft biologic and biomechanical properties, absence of tissue toxicity due to cleaning solutions used, and reduced implant antigenicity.
摘要翻译：本发明包括一种用于在植入有需要的接受者之前安全，有效和有效地汇集用于治疗的组织的新方法。在一个实施方案中，该方法包括灌注多孔植入物，其实现期望因子的有效相互渗透和植入物孔隙中的不期望因子的去除，植入物的清洁，植入物的有效钝化（病原体，微生物，细胞的灭活，病毒等及其抗原性的降低），以及通过这种处理产生的新型植入物。该过程提出了一种系统，其中压力循环的速率，压力循环的事实和压力循环的幅度导致高度清洁的组织和用于植入的其它植入物。该过程的目标去污目标包括细菌污染减少约一（1）至十二（12）次，包膜病毒污染减少约一（1）至十五（15）次，最多约五（ 5）无包膜病毒污染减少，内毒素减少约二（2）至十（10）倍，维持植入物或移植物生物学和生物力学性质，由于使用的清洁溶液不存在组织毒性，并减少植入抗原性。

9. 发明授权

US06645430B1 Method and apparatus for processing device with fluid submersion 有权
标题翻译：流体浸没处理装置的方法和装置
公开(公告)号：US06645430B1
公开(公告)日：2003-11-11
申请号：US09650839
申请日：2000-08-30
申请人： Szu-Min Lin
发明人： Szu-Min Lin
IPC分类号： A61L200
CPC分类号： A61L2/208 , A61L2/14 , A61L2/186 , A61L2/22 , A61L2/24 , A61L2/26 , A61L2202/122 , A61L2202/14 , A61L2202/17 , A61L2202/24
摘要： A container and method for cleaning, rinsing, disinfecting, or sterilizing a device disposes an instrument in a container below partition having an aperture for passing fluid. The container is filled to a level above the partition to ensure that the device is submerged in the fluid.
摘要翻译：用于清洁，冲洗，消毒或消毒设备的容器和方法将仪器置于具有用于通过流体的孔的隔板下方的容器中。将容器填充到隔板上方的水平面上，以确保设备浸没在流体中。

10. 发明授权

US06630105B1 Method and apparatus for the gas phase decontamination of chemical and biological agents 失效
标题翻译：化学和生物制剂气相去污的方法和装置
公开(公告)号：US06630105B1
公开(公告)日：2003-10-07
申请号：US09675898
申请日：2000-09-27
申请人： Hugh J. O'Neill , Kenneth L. Brubaker
发明人： Hugh J. O'Neill , Kenneth L. Brubaker
IPC分类号： A61L200
CPC分类号： A61L2/208 , A61L2/202 , A61L2202/25 , B01D53/007 , B01D53/22
摘要： An apparatus and method for decontaminating chemical and biological agents using the reactive properties of both the single atomic oxygen and the hydroxyl radical for the decontamination of chemical and biological agents. The apparatus is self contained and portable and allows for the application of gas reactants directly at the required decontamination point. The system provides for the use of ultraviolet light of a specific spectral range to photolytically break down ozone into molecular oxygen and hydroxyl radicals where some of the molecular oxygen is in the first excited state. The excited molecular oxygen will combine with water vapor to produce two hydroxyl radicals.
摘要翻译：使用单原子氧和羟基自由基的反应性去除化学和生物试剂的化学和生物试剂去污的装置和方法。该设备是独立的和便携的，并允许气体反应物直接应用于所需的去污点。该系统提供使用特定光谱范围的紫外光光解地将臭氧分解成分子氧和羟基，其中一些分子氧处于第一激发态。激发的分子氧将与水蒸汽结合以产生两个羟基自由基。

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