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    • 2. 发明申请
    • E. coli extract for protein synthesis
    • 大肠杆菌提取物用于蛋白质合成
    • US20020034559A1
    • 2002-03-21
    • US09848449
    • 2001-05-03
    • Yuping AmbuelThomas R. Van OosbreeMark R. McCormickRobert C. Mierendorf
    • A61K035/66A61K035/68C12P021/06A01N063/02
    • C07K14/245C12P21/02
    • There is now a market for kits containing the necessary components for performing protein synthesis reactions using template DNA of the experimenter. One category of existing system for performing protein synthesis reactions is based on an S-30 extract from the bacteria E. coli. It is disclosed here that a simple fractionation process can dramatically improve the performance of an S-30 prokaryotic protein synthesis reaction mixture. In one embodiment, the fractionation is a simple freezing and thawing of an S-30 extract combined with a supplemental mix, followed by centrifugation. The resulting fractionated S-30 reaction mixture yields more full-length target protein and less non-full length or non-target protein than possible using prior art S-30 systems.
    • 现在有一个包含使用实验者的模板DNA进行蛋白质合成反应的必要组分的试剂盒的市场。 用于进行蛋白质合成反应的现有系统的一个类别是基于来自细菌大肠杆菌的S-30提取物。 这里公开了简单的分级方法可以显着改善S-30原核生物蛋白质合成反应混合物的性能。 在一个实施方案中,分馏是与补充混合物组合的S-30提取物的简单冷冻和解冻,然后离心。 所得到的分级的S-30反应混合物比现有技术的S-30系统产生更多的全长靶蛋白和较少的非全长或非靶蛋白。
    • 4. 发明申请
    • Use of emu oil and its various fractions as a carrier for antifungal, antibacterial, and antiviral medications & preparations
    • 使用em油及其各种馏分作为抗真菌,抗菌和抗病毒药物和制剂的载体
    • US20040208860A1
    • 2004-10-21
    • US10843277
    • 2004-05-11
    • Sean Farmer
    • A61K035/12A61K035/66
    • A61K31/496A61K9/0014A61K9/0034A61K31/63A61K31/7034A61K35/74A61K35/742A61K35/744A61K35/745A61K35/747A61K47/44Y02A50/473Y10S514/887A61K2300/00
    • An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatments. This lipid material is extracted from the Emu (Dromais Novae-Hollandiae), an indigenous bird of Australia and New Zealand. The present invention also discloses therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain, comprising a supernatant or filtrate of said culture suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. Additionally, the aforementioned therapeutic composition may also include an anti-microbial, anti-mycotic, and/or anti-viral agent. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain suitable for topical application to the skin or mucosal membranes of a mammal. Similarly, the aforementioned method may also employ a therapeutic composition additionally containing an anti-microbial, anti-mycotic, and/or anti-viral agent.
    • 公开了可用作抗微生物制剂的载体的动物来源的脂质。 包括Em u油在内的药物和其他制剂也被描述为抗菌,抗真菌和抗病毒治疗中非常有用的成分。 这种脂质物质是从澳大利亚和新西兰的一只土着鸟的Emu(Dromais Novae-Hollandiae)中提取出来的。 本发明还公开了包含Em u油与凝结芽孢杆菌或绿脓假单胞菌菌株的细胞外产物组合的治疗组合物,其包含适于局部施用于哺乳动物皮肤或粘膜的所述培养物的上清液或滤液,其用于 抑制细菌,酵母,真菌,病毒及其组合的生长。 另外,上述治疗组合物还可以包括抗微生物,抗真菌和/或抗病毒剂。 本发明还公开了通过局部应用包含Em u油与凝结芽孢杆菌或绿脓假单胞菌菌株的细胞外产物组合的治疗组合物来抑制细菌,酵母,真菌,病毒及其组合的生长的治疗方法和治疗系统 适合局部应用于哺乳动物的皮肤或粘膜。 类似地,上述方法还可以使用另外含有抗微生物,抗真菌和/或抗病毒剂的治疗组合物。
    • 5. 发明申请
    • Direct-fed microbial
    • 直接饲养的微生物
    • US20030129165A1
    • 2003-07-10
    • US09912049
    • 2001-07-24
    • AgTech Products, Inc.
    • Thomas G. RehbergerJohn P. O'Neill
    • C12N001/20A23K001/00A61K035/66A61K035/74
    • C12R1/01A23K10/16A23K10/18A23K50/10C12N1/20
    • An isolated microorganism comprising a Propionibacteria strain. When the microorganism is fed to a ruminant, protein and fat levels in milk produced by the ruminant are increased, while body condition and milk production levels are maintained. When fed to the ruminant, the microorganism also has positive effects on various metabolic hormones and metabolites, e.g, an increase in energy balance, plasma non-esterified fatty acids levels, and plasma leptin level. Supplementation with propionibacteria reduced dry matter intake but did not affect milk production in the cows. Therefore, the propionibacteria of the invention made the cows more energy efficient as cows produced the same amount of milk, yet consumed less dry matter.
    • 包含丙酸杆菌菌株的分离的微生物。 当微生物饲喂反刍动物时,由反刍动物产生的乳汁中的蛋白质和脂肪水平增加,同时维持身体状况和产奶量。 当喂养反刍动物时,微生物也对各种代谢激素和代谢物具有积极作用,例如能量平衡的增加,血浆未酯化的脂肪酸水平和血浆瘦素水平。 补充丙酸杆菌减少干物质摄入量,但不影响奶牛的产奶量。 因此,本发明的丙酸杆菌使得牛产生相同量的牛奶,同时消耗更少的干物质,使奶牛更节能。
    • 8. 发明申请
    • Use of emu oil and its various fractions as a carrier for antifungal, antibacterial, and antiviral medications & preperations
    • 使用em u油及其各种馏分作为抗真菌,抗菌和抗病毒药物和前药的载体
    • US20010033838A1
    • 2001-10-25
    • US09850466
    • 2001-05-07
    • Sean Farmer
    • A61K035/66A61K035/12
    • A61K31/496A61K9/0014A61K9/0034A61K31/63A61K31/7034A61K35/74A61K35/742A61K35/744A61K35/745A61K35/747A61K47/44Y02A50/473Y10S514/887A61K2300/00
    • An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatments. This lipid material is extracted from the Emu (Dromais novae-hollandiae), an indigenous bird of Australia and New Zealand. The present invention also discloses therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain, comprising a supernatant or filtrate of said culture suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. Additionally, the aforementioned therapeutic composition may also include an anti-microbial, anti-mycotic, and/or anti-viral agent. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain suitable for topical application to the skin or mucosal membranes of a mammal. Similarly, the aforementioned method may also employ a therapeutic composition additionally containing an anti-microbial, anti-mycotic, and/or anti-viral agent.
    • 公开了可用作抗微生物制剂的载体的动物来源的脂质。 包括Em u油在内的药物和其他制剂也被描述为抗菌,抗真菌和抗病毒治疗中非常有用的成分。 这种脂质物质是从澳大利亚和新西兰的一只土着鸟的Emu(Dromais novae-hollandiae)提取的。 本发明还公开了包含Em u油与凝结芽孢杆菌或绿脓假单胞菌菌株的细胞外产物组合的治疗组合物,其包含适于局部施用于哺乳动物皮肤或粘膜的所述培养物的上清液或滤液,其用于 抑制细菌,酵母,真菌,病毒及其组合的生长。 另外,上述治疗组合物还可以包括抗微生物剂,抗真菌剂和/或抗病毒剂。 本发明还公开了通过局部应用包含Em u油与凝结芽孢杆菌或绿脓假单胞菌菌株的细胞外产物组合的治疗组合物来抑制细菌,酵母,真菌,病毒及其组合的生长的治疗方法和治疗系统 适合局部应用于哺乳动物的皮肤或粘膜。 类似地,上述方法还可以使用另外含有抗微生物,抗真菌和/或抗病毒剂的治疗组合物。
    • 10. 发明申请
    • Use of Emu Oil and its various fractions as a carrier for antifungal, antibacterial, and antiviral medications & preparations
    • 使用Em油及其各种馏分作为抗真菌,抗菌和抗病毒药物和制剂的载体
    • US20030170334A1
    • 2003-09-11
    • US10384840
    • 2003-03-10
    • Sean Farmer
    • A61K035/66A61K035/00
    • A61K31/496A61K9/0014A61K9/0034A61K31/63A61K31/7034A61K35/74A61K35/742A61K35/744A61K35/745A61K35/747A61K47/44Y02A50/473Y10S514/887A61K2300/00
    • An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatments. This lipid material is extracted from the Emu (Dromais Novae-Hollandiae), an indigenous bird of Australia and New Zealand. The present invention also discloses therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain, comprising a supernatant or filtrate of said culture suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. Additionally, the aforementioned therapeutic composition may also include an anti-microbial, anti-mycotic, and/or anti-viral agent. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain suitable for topical application to the skin or mucosal membranes of a mammal. Similarly, the aforementioned method may also employ a therapeutic composition additionally containing an anti-microbial, anti-mycotic, and/or anti-viral agent.
    • 公开了可用作抗微生物制剂的载体的动物来源的脂质。 包括Em u油在内的药物和其他制剂也被描述为抗菌,抗真菌和抗病毒治疗中非常有用的成分。 这种脂质物质是从澳大利亚和新西兰的一只土着鸟的Emu(Dromais Novae-Hollandiae)中提取出来的。 本发明还公开了包含Em u油与凝结芽孢杆菌或绿脓假单胞菌菌株的细胞外产物组合的治疗组合物,其包含适于局部施用于哺乳动物皮肤或粘膜的所述培养物的上清液或滤液,其用于 抑制细菌,酵母,真菌,病毒及其组合的生长。 另外,上述治疗组合物还可以包括抗微生物剂,抗真菌剂和/或抗病毒剂。 本发明还公开了通过局部应用包含Em u油与凝结芽孢杆菌或绿脓假单胞菌菌株的细胞外产物组合的治疗组合物来抑制细菌,酵母,真菌,病毒及其组合的生长的治疗方法和治疗系统 适合局部应用于哺乳动物的皮肤或粘膜。 类似地,上述方法还可以使用另外含有抗微生物,抗真菌和/或抗病毒剂的治疗组合物。